Logo of aacJournal InfoAuthorsReviewersSubscribersPermissionsJournals.ASM.orgJournalAAC ArticleJournal InfoAuthorsReviewers

Volume 59(1);  January 2015

Articles from this journal are usually available in PMC after a 6-month delay (embargo). Some articles may be available sooner.

Minireview

Anke E. Kip, Manica Balasegaram, Jos H. Beijnen, Jan H. M. Schellens, Peter J. de Vries, Thomas P. C. Dorlo
Antimicrob Agents Chemother. Jan 2015; 59(1): 1–14. Published online Nov 3, 2014. doi: 10.1128/AAC.04298-14
PMCID:
PMC4291336

Mechanisms of Action: Physiological Effects

Probing the Molecular Mechanism of Hypericin-Induced Parasite Death Provides Insight into the Role of Spermidine beyond Redox Metabolism in Leishmania donovani
Shalini Singh, Shyamali Sarma, Shashank P. Katiyar, Mousumi Das, Ruchika Bhardwaj, Durai Sundar, Vikash Kumar Dubey
Antimicrob Agents Chemother. Jan 2015; 59(1): 15–24. Published online Oct 13, 2014. doi: 10.1128/AAC.04169-14
PMCID:
PMC4291343
Shawn Flanagan, Edward E. McKee, Debaditya Das, Paul M. Tulkens, Hiromi Hosako, Jill Fiedler-Kelly, Julie Passarell, Ann Radovsky, Philippe Prokocimer
Antimicrob Agents Chemother. Jan 2015; 59(1): 178–185. Published online Oct 20, 2014. doi: 10.1128/AAC.03684-14
PMCID:
PMC4291347
Identification of Inhibitors of a Bacterial Sigma Factor Using a New High-Throughput Screening Assay
S. A. El-Mowafi, E. Sineva, J. N. Alumasa, H. Nicoloff, J. W. Tomsho, S. E. Ades, K. C. Keiler
Antimicrob Agents Chemother. Jan 2015; 59(1): 193–205. Published online Oct 20, 2014. doi: 10.1128/AAC.03979-14
PMCID:
PMC4291351
Antimalarial Action of Artesunate Involves DNA Damage Mediated by Reactive Oxygen Species
Anusha M. Gopalakrishnan, Nirbhay Kumar
Antimicrob Agents Chemother. Jan 2015; 59(1): 317–325. Published online Oct 27, 2014. doi: 10.1128/AAC.03663-14
PMCID:
PMC4291367
Michael J. Schlosser, Hiromi Hosako, Ann Radovsky, Mark T. Butt, Dragomir Draganov, Jenifer Vija, Frederick Oleson
Antimicrob Agents Chemother. Jan 2015; 59(1): 475–481. Published online Nov 10, 2014. doi: 10.1128/AAC.03950-14
PMCID:
PMC4291389
Mechanism of β-Lactam Action in Streptococcus pneumoniae: the Piperacillin Paradox
Jules Philippe, Benoit Gallet, Cécile Morlot, Dalia Denapaite, Regine Hakenbeck, Yuxin Chen, Thierry Vernet, André Zapun
Antimicrob Agents Chemother. Jan 2015; 59(1): 609–621. Published online Nov 10, 2014. doi: 10.1128/AAC.04283-14
PMCID:
PMC4291406
Novel Strategy for Biofilm Inhibition by Using Small Molecules Targeting Molecular Chaperone DnaK
Ken-ichi Arita-Morioka, Kunitoshi Yamanaka, Yoshimitsu Mizunoe, Teru Ogura, Shinya Sugimoto
Antimicrob Agents Chemother. Jan 2015; 59(1): 633–641. Published online Nov 17, 2014. doi: 10.1128/AAC.04465-14
PMCID:
PMC4291377

Mechanisms of Resistance

Activity Spectrum of Colicins Produced by Shigella sonnei and Genetic Mechanism of Colicin Resistance in Conspecific S. sonnei Strains and Escherichia coli
Fatema Calcuttawala, Chellaram Hariharan, Gururaja P. Pazhani, Santanu Ghosh, Thandavarayan Ramamurthy
Antimicrob Agents Chemother. Jan 2015; 59(1): 152–158. Published online Oct 20, 2014. doi: 10.1128/AAC.04122-14
PMCID:
PMC4291344
Oxidative Stress Enhances Cephalosporin Resistance of Enterococcus faecalis through Activation of a Two-Component Signaling System
Dušanka Djorić, Christopher J. Kristich
Antimicrob Agents Chemother. Jan 2015; 59(1): 159–169. Published online Oct 20, 2014. doi: 10.1128/AAC.03984-14
PMCID:
PMC4291345
Genomic Analysis of Reduced Susceptibility to Tigecycline in Enterococcus faecium
Vincent Cattoir, Christophe Isnard, Thibaud Cosquer, Arlène Odhiambo, Fiona Bucquet, François Guérin, Jean-Christophe Giard
Antimicrob Agents Chemother. Jan 2015; 59(1): 239–244. Published online Oct 27, 2014. doi: 10.1128/AAC.04174-14
PMCID:
PMC4291356
Bacterial Resistance to Leucyl-tRNA Synthetase Inhibitor GSK2251052 Develops during Treatment of Complicated Urinary Tract Infections
Karen O'Dwyer, Aaron T. Spivak, Karen Ingraham, Sharon Min, David J. Holmes, Charles Jakielaszek, Stephen Rittenhouse, Alan L. Kwan, George P. Livi, Ganesh Sathe, Elizabeth Thomas, Stephanie Van Horn, Linda A. Miller, Monique Twynholm, John Tomayko, Marybeth Dalessandro, Madelyn Caltabiano, Nicole E. Scangarella-Oman, James R. Brown
Antimicrob Agents Chemother. Jan 2015; 59(1): 289–298. Published online Oct 27, 2014. doi: 10.1128/AAC.03774-14
PMCID:
PMC4291364
Evaluation of Antimalarial Resistance Marker Polymorphism in Returned Migrant Workers in China
Jun Feng, Jun Li, He Yan, Xinyu Feng, Zhigui Xia
Antimicrob Agents Chemother. Jan 2015; 59(1): 326–330. Published online Oct 27, 2014. doi: 10.1128/AAC.04144-14
PMCID:
PMC4291368
Target-Based Resistance in Pseudomonas aeruginosa and Escherichia coli to NBTI 5463, a Novel Bacterial Type II Topoisomerase Inhibitor
Asha S. Nayar, Thomas J. Dougherty, Folkert Reck, Jason Thresher, Ning Gao, Adam B. Shapiro, David E. Ehmann
Antimicrob Agents Chemother. Jan 2015; 59(1): 331–337. Published online Oct 27, 2014. doi: 10.1128/AAC.04077-14
PMCID:
PMC4291369
First Report of a Clinical, Multidrug-Resistant Enterobacteriaceae Isolate Coharboring Fosfomycin Resistance Gene fosA3 and Carbapenemase Gene blaKPC-2 on the Same Transposon, Tn1721
Gang Li, Ying Zhang, Dexi Bi, Pinghua Shen, Fuqi Ai, Hong Liu, Yueru Tian, Yiming Ma, Bei Wang, Kumar Rajakumar, Hong-Yu Ou, Xiaofei Jiang
Antimicrob Agents Chemother. Jan 2015; 59(1): 338–343. Published online Nov 3, 2014. doi: 10.1128/AAC.03061-14
PMCID:
PMC4291370
Artemisinins, New Miconazole Potentiators Resulting in Increased Activity against Candida albicans Biofilms
Kaat De Cremer, Ellen Lanckacker, Tanne L. Cools, Marijke Bax, Katrijn De Brucker, Paul Cos, Bruno P. A. Cammue, Karin Thevissen
Antimicrob Agents Chemother. Jan 2015; 59(1): 421–426. Published online Nov 3, 2014. doi: 10.1128/AAC.04229-14
PMCID:
PMC4291436
The Resistome of Pseudomonas aeruginosa in Relationship to Phenotypic Susceptibility
Veronica N. Kos, Maxime Déraspe, Robert E. McLaughlin, James D. Whiteaker, Paul H. Roy, Richard A. Alm, Jacques Corbeil, Humphrey Gardner
Antimicrob Agents Chemother. Jan 2015; 59(1): 427–436. Published online Nov 3, 2014. doi: 10.1128/AAC.03954-14
PMCID:
PMC4291382
Disparities in Capreomycin Resistance Levels Associated with the rrs A1401G Mutation in Clinical Isolates of Mycobacterium tuberculosis
Analise Z. Reeves, Patricia J. Campbell, Melisa J. Willby, James E. Posey
Antimicrob Agents Chemother. Jan 2015; 59(1): 444–449. Published online Nov 10, 2014. doi: 10.1128/AAC.04438-14
PMCID:
PMC4291384
Contribution of Clinically Derived Mutations in ERG11 to Azole Resistance in Candida albicans
Stephanie A. Flowers, Brendan Colón, Sarah G. Whaley, Mary A. Schuler, P. David Rogers
Antimicrob Agents Chemother. Jan 2015; 59(1): 450–460. Published online Nov 10, 2014. doi: 10.1128/AAC.03470-14
PMCID:
PMC4291385
Molecular Characterization of Fluoroquinolone Resistance in Nontypeable Haemophilus influenzae Clinical Isolates
Carmen Puig, José Manuel Tirado-Vélez, Laura Calatayud, Fe Tubau, Junkal Garmendia, Carmen Ardanuy, Sara Marti, Adela G. de la Campa, Josefina Liñares
Antimicrob Agents Chemother. Jan 2015; 59(1): 461–466. Published online Nov 10, 2014. doi: 10.1128/AAC.04005-14
PMCID:
PMC4291387
Genomic and Transcriptomic Analyses of Colistin-Resistant Clinical Isolates of Klebsiella pneumoniae Reveal Multiple Pathways of Resistance
Meredith S. Wright, Yo Suzuki, Marcus B. Jones, Steven H. Marshall, Susan D. Rudin, David van Duin, Keith Kaye, Michael R. Jacobs, Robert A. Bonomo, Mark D. Adams
Antimicrob Agents Chemother. Jan 2015; 59(1): 536–543. Published online Nov 10, 2014. doi: 10.1128/AAC.04037-14
PMCID:
PMC4291396
Induction of Candida albicans Drug Resistance Genes by Hybrid Zinc Cluster Transcription Factors
Sabrina Schneider, Joachim Morschhäuser
Antimicrob Agents Chemother. Jan 2015; 59(1): 558–569. Published online Nov 10, 2014. doi: 10.1128/AAC.04448-14
PMCID:
PMC4291399
Clostridium difficile Isolates with High Linezolid MICs Harbor the Multiresistance Gene cfr
Mercedes Marín, Adoración Martín, Luis Alcalá, Emilia Cercenado, Cristina Iglesias, Elena Reigadas, Emilio Bouza
Antimicrob Agents Chemother. Jan 2015; 59(1): 586–589. Published online Nov 10, 2014. doi: 10.1128/AAC.04082-14
PMCID:
PMC4291439
Metallo-β-Lactamase-Producing Bacteroides Species Can Shield Other Members of the Gut Microbiota from Antibiotics
Usha Stiefel, Mary Ann Tima, Michelle M. Nerandzic
Antimicrob Agents Chemother. Jan 2015; 59(1): 650–653. Published online Oct 6, 2014. doi: 10.1128/AAC.03719-14
PMCID:
PMC4291410
Molecular Characterization of blaNDM-5 Carried on an IncFII Plasmid in an Escherichia coli Isolate from a Nontraveler Patient in Spain
Cristina Pitart, Mar Solé, Ignasi Roca, Angely Román, Asunción Moreno, Jordi Vila, Francesc Marco
Antimicrob Agents Chemother. Jan 2015; 59(1): 659–662. Published online Oct 13, 2014. doi: 10.1128/AAC.04040-14
PMCID:
PMC4291412
Surface Glycosaminoglycans Protect Eukaryotic Cells against Membrane-Driven Peptide Bacteriocins
Rebeca Martín, Susana Escobedo, Carla Martín, Ainara Crespo, Luis M. Quiros, Juan E. Suarez
Antimicrob Agents Chemother. Jan 2015; 59(1): 677–681. Published online Oct 20, 2014. doi: 10.1128/AAC.04427-14
PMCID:
PMC4291419
Atovaquone Tolerance in Plasmodium falciparum Parasites Selected for High-Level Resistance to a Dihydroorotate Dehydrogenase Inhibitor
Jennifer L. Guler, John White, III, Margaret A. Phillips, Pradipsinh K. Rathod
Antimicrob Agents Chemother. Jan 2015; 59(1): 686–689. Published online Oct 20, 2014. doi: 10.1128/AAC.02347-14
PMCID:
PMC4291421
Contaminated Handwashing Sinks as the Source of a Clonal Outbreak of KPC-2-Producing Klebsiella oxytoca on a Hematology Ward
Eva Leitner, Gernot Zarfel, Josefa Luxner, Kathrin Herzog, Shiva Pekard-Amenitsch, Martin Hoenigl, Thomas Valentin, Gebhard Feierl, Andrea J. Grisold, Christoph Högenauer, Heinz Sill, Robert Krause, Ines Zollner-Schwetz
Antimicrob Agents Chemother. Jan 2015; 59(1): 714–716. Published online Oct 27, 2014. doi: 10.1128/AAC.04306-14
PMCID:
PMC4291428
Identification of TEM-135 β-Lactamase in Neisseria gonorrhoeae Strains Carrying African and Toronto Plasmids in Argentina
R. Gianecini, C. Oviedo, A. Littvik, E. Mendez, L. Piccoli, S. Montibello, P. Galarza
Antimicrob Agents Chemother. Jan 2015; 59(1): 717–720. Published online Nov 3, 2014. doi: 10.1128/AAC.03838-14
PMCID:
PMC4291429
Chromosome-Mediated Multidrug Resistance in Salmonella enterica Serovar Typhi
Chien-Shun Chiou, Munirul Alam, Jung-Che Kuo, Yen-Yi Liu, Pei-Jen Wang
Antimicrob Agents Chemother. Jan 2015; 59(1): 721–723. Published online Nov 3, 2014. doi: 10.1128/AAC.04081-14
PMCID:
PMC4291426
Overproduction of the MtrCDE Efflux Pump in Neisseria gonorrhoeae Produces Unexpected Changes in Cellular Transcription Patterns
Elizabeth A. Ohneck, Maira Goytia, Corinne E. Rouquette-Loughlin, Sandeep J. Joseph, Timothy D. Read, Ann E. Jerse, William M. Shafer
Antimicrob Agents Chemother. Jan 2015; 59(1): 724–726. Published online Nov 3, 2014. doi: 10.1128/AAC.04148-14
PMCID:
PMC4291417
Reduced Polymorphism in the Kelch Propeller Domain in Plasmodium vivax Isolates from Cambodia
Jean Popovici, Sokheng Kao, Leanghor Eal, Sophalai Bin, Saorin Kim, Didier Ménard
Antimicrob Agents Chemother. Jan 2015; 59(1): 730–733. Published online Nov 10, 2014. doi: 10.1128/AAC.03908-14
PMCID:
PMC4291442
In Vivo Selection of Plasmodium falciparum Pfcrt and Pfmdr1 Variants by Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine in Burkina Faso
Vito Baraka, Halidou Tinto, Innocent Valea, Robert Fitzhenry, Christopher Delgado-Ratto, Martin K. Mbonye, Chantal Van Overmeir, Anna Rosanas-Urgell, Jean-Pierre Van geertruyden, Umberto D'Alessandro, Annette Erhart
Antimicrob Agents Chemother. Jan 2015; 59(1): 734–737. Published online Nov 17, 2014. doi: 10.1128/AAC.03647-14
PMCID:
PMC4291431
Complete Nucleotide Sequence of cfr-Carrying IncX4 Plasmid pSD11 from Escherichia coli
Jian Sun, Hui Deng, Liang Li, Mu-Ya Chen, Liang-Xing Fang, Qiu-E Yang, Ya-Hong Liu, Xiao-Ping Liao
Antimicrob Agents Chemother. Jan 2015; 59(1): 738–741. Published online Nov 17, 2014. doi: 10.1128/AAC.04388-14
PMCID:
PMC4291432

Susceptibility

JPC-2997, a New Aminomethylphenol with High In Vitro and In Vivo Antimalarial Activities against Blood Stages of Plasmodium
Geoffrey W. Birrell, Marina Chavchich, Arba L. Ager, Hong-Ming Shieh, Gavin D. Heffernan, Wenyi Zhao, Peter E. Krasucki, Kurt W. Saionz, Jacek Terpinski, Guy A. Schiehser, Laura R. Jacobus, G. Dennis Shanks, David P. Jacobus, Michael D. Edstein
Antimicrob Agents Chemother. Jan 2015; 59(1): 170–177. Published online Oct 20, 2014. doi: 10.1128/AAC.03762-14
PMCID:
PMC4291346
Antimicrobial Susceptibility among Clinical Nocardia Species Identified by Multilocus Sequence Analysis
Lisa R. McTaggart, Jennifer Doucet, Maria Witkowska, Susan E. Richardson
Antimicrob Agents Chemother. Jan 2015; 59(1): 269–275. Published online Oct 27, 2014. doi: 10.1128/AAC.02770-14
PMCID:
PMC4291361
Synergistic Interactions of Vancomycin with Different Antibiotics against Escherichia coli: Trimethoprim and Nitrofurantoin Display Strong Synergies with Vancomycin against Wild-Type E. coli
Alice Zhou, Tina Manzhu Kang, Jessica Yuan, Casey Beppler, Caroline Nguyen, Zhiyuan Mao, Minh Quan Nguyen, Pamela Yeh, Jeffrey H. Miller
Antimicrob Agents Chemother. Jan 2015; 59(1): 276–281. Published online Oct 27, 2014. doi: 10.1128/AAC.03502-14
PMCID:
PMC4291362
Optimization of a Nucleic Acid-Based Reporter System To Detect Mycobacterium tuberculosis Antibiotic Sensitivity
Matthew C. Mulvey, Margaret Lemmon, Stephanie Rotter, Jonathan Lees, Leo Einck, Carol A. Nacy
Antimicrob Agents Chemother. Jan 2015; 59(1): 407–413. Published online Nov 3, 2014. doi: 10.1128/AAC.03135-14
PMCID:
PMC4291379
Evaluation of Pyrosequencing for Detecting Extensively Drug-Resistant Mycobacterium tuberculosis among Clinical Isolates from Four High-Burden Countries
Kanchan Ajbani, Shou-Yean Grace Lin, Camilla Rodrigues, Duylinh Nguyen, Francine Arroyo, Janice Kaping, Lynn Jackson, Richard S. Garfein, Donald Catanzaro, Kathleen Eisenach, Thomas C. Victor, Valeru Crudu, Maria Tarcela Gler, Nazir Ismail, Edward Desmond, Antonino Catanzaro, Timothy C. Rodwell
Antimicrob Agents Chemother. Jan 2015; 59(1): 414–420. Published online Nov 3, 2014. doi: 10.1128/AAC.03614-14
PMCID:
PMC4291380
In Vitro Antibacterial Activity of AZD0914, a New Spiropyrimidinetrione DNA Gyrase/Topoisomerase Inhibitor with Potent Activity against Gram-Positive, Fastidious Gram-Negative, and Atypical Bacteria
Michael D. Huband, Patricia A. Bradford, Linda G. Otterson, Gregory S. Basarab, Amy C. Kutschke, Robert A. Giacobbe, Sara A. Patey, Richard A. Alm, Michele R. Johnstone, Marie E. Potter, Paul F. Miller, John P. Mueller
Antimicrob Agents Chemother. Jan 2015; 59(1): 467–474. Published online Nov 10, 2014. doi: 10.1128/AAC.04124-14
PMCID:
PMC4291388
Multicenter Study of Isavuconazole MIC Distributions and Epidemiological Cutoff Values for the Cryptococcus neoformans-Cryptococcus gattii Species Complex Using the CLSI M27-A3 Broth Microdilution Method
A. Espinel-Ingroff, A. Chowdhary, G. M. Gonzalez, J. Guinea, F. Hagen, J. F. Meis, G. R. Thompson, III, J. Turnidge
Antimicrob Agents Chemother. Jan 2015; 59(1): 666–668. Published online Oct 13, 2014. doi: 10.1128/AAC.04055-14
PMCID:
PMC4291414
High-Content Screening Technology Combined with a Human Granuloma Model as a New Approach To Evaluate the Activities of Drugs against Mycobacterium tuberculosis
Mayra Silva-Miranda, Euloge Ekaza, Adrien Breiman, Karim Asehnoune, David Barros-Aguirre, Kevin Pethe, Fanny Ewann, Priscille Brodin, Lluís Ballell-Pages, Frédéric Altare
Antimicrob Agents Chemother. Jan 2015; 59(1): 693–697. Published online Oct 27, 2014. doi: 10.1128/AAC.03705-14
PMCID:
PMC4291390
In Vitro and Intracellular Activities of Peptide Deformylase Inhibitor GSK1322322 against Legionella pneumophila Isolates
Jacques Dubois, Maïtée Dubois, Jean-François Martel, Kelly Aubart, Deborah Butler
Antimicrob Agents Chemother. Jan 2015; 59(1): 707–710. Published online Oct 27, 2014. doi: 10.1128/AAC.04006-14
PMCID:
PMC4291349
In Vitro Efficacy of High-Dose Tobramycin against Burkholderia cepacia Complex and Stenotrophomonas maltophilia Isolates from Cystic Fibrosis Patients
Anina Ratjen, Yvonne Yau, Jillian Wettlaufer, Larissa Matukas, James E. A. Zlosnik, David P. Speert, John J. LiPuma, Elizabeth Tullis, Valerie Waters
Antimicrob Agents Chemother. Jan 2015; 59(1): 711–713. Published online Oct 27, 2014. doi: 10.1128/AAC.04123-14
PMCID:
PMC4291427

Analytical Procedures

Detection of Single-Nucleotide Polymorphisms in Plasmodium falciparum by PCR Primer Extension and Lateral Flow Immunoassay
A. P. H. A. Moers, R. L. Hallett, R. Burrow, H. D. F. H. Schallig, C. J. Sutherland, A. van Amerongen
Antimicrob Agents Chemother. Jan 2015; 59(1): 365–371. Published online Nov 3, 2014. doi: 10.1128/AAC.03395-14
PMCID:
PMC4291373
L. M. Upton, P. M. Brock, T. S. Churcher, A. C. Ghani, P. W. Gething, M. J. Delves, K. A. Sala, D. Leroy, R. E. Sinden, A. M. Blagborough
Antimicrob Agents Chemother. Jan 2015; 59(1): 490–497. Published online Nov 10, 2014. doi: 10.1128/AAC.03942-14
PMCID:
PMC4291391

Antiviral Agents

The Bioactive Lipid 4-Hydroxyphenyl Retinamide Inhibits Flavivirus Replication
Margot Carocci, Stephen M. Hinshaw, Mary A. Rodgers, Valerie A. Villareal, Dominique J. Burri, Rajendra Pilankatta, Natalya P. Maharaj, Michaela U. Gack, Eric J. Stavale, Kelly L. Warfield, Priscilla L. Yang
Antimicrob Agents Chemother. Jan 2015; 59(1): 85–95. Published online Oct 13, 2014. doi: 10.1128/AAC.04177-14
PMCID:
PMC4291433
Laurence H. Arnold, Simone Kunzelmann, Martin R. Webb, Ian A. Taylor
Antimicrob Agents Chemother. Jan 2015; 59(1): 186–192. Published online Oct 20, 2014. doi: 10.1128/AAC.03903-14
PMCID:
PMC4291348
Inhibition of Endoplasmic Reticulum-Resident Glucosidases Impairs Severe Acute Respiratory Syndrome Coronavirus and Human Coronavirus NL63 Spike Protein-Mediated Entry by Altering the Glycan Processing of Angiotensin I-Converting Enzyme 2
Xuesen Zhao, Fang Guo, Mary Ann Comunale, Anand Mehta, Mohit Sehgal, Pooja Jain, Andrea Cuconati, Hanxin Lin, Timothy M. Block, Jinhong Chang, Ju-Tao Guo
Antimicrob Agents Chemother. Jan 2015; 59(1): 206–216. Published online Oct 27, 2014. doi: 10.1128/AAC.03999-14
PMCID:
PMC4291352
Human Cytomegalovirus Resistance to Deoxyribosylindole Nucleosides Maps to a Transversion Mutation in the Terminase Subunit-Encoding Gene UL89
Brian G. Gentry, Quang Phan, Ellie D. Hall, Julie M. Breitenbach, Katherine Z. Borysko, Jeremy P. Kamil, Leroy B. Townsend, John C. Drach
Antimicrob Agents Chemother. Jan 2015; 59(1): 226–232. Published online Oct 27, 2014. doi: 10.1128/AAC.03686-14
PMCID:
PMC4291354
Pharmacokinetics, Safety, and Tolerability of Faldaprevir in Patients with Renal Impairment
Fenglei Huang, Viktoria Moschetti, Benjamin Lang, Atef Halabi, Marc Petersen-Sylla, Chan-Loi Yong, Mabrouk Elgadi
Antimicrob Agents Chemother. Jan 2015; 59(1): 251–257. Published online Oct 27, 2014. doi: 10.1128/AAC.03359-14
PMCID:
PMC4291359
The R262K Substitution Combined with H51Y in HIV-1 Subtype B Integrase Confers Low-Level Resistance against Dolutegravir
Vincent Cutillas, Thibault Mesplede, Kaitlin Anstett, Said Hassounah, Mark A. Wainberg
Antimicrob Agents Chemother. Jan 2015; 59(1): 310–316. Published online Oct 27, 2014. doi: 10.1128/AAC.04274-14
PMCID:
PMC4291366
Antiviral Characteristics of GSK1265744, an HIV Integrase Inhibitor Dosed Orally or by Long-Acting Injection
Tomokazu Yoshinaga, Masanori Kobayashi, Takahiro Seki, Shigeru Miki, Chiaki Wakasa-Morimoto, Akemi Suyama-Kagitani, Shinobu Kawauchi-Miki, Teruhiko Taishi, Takashi Kawasuji, Brian A. Johns, Mark R. Underwood, Edward P. Garvey, Akihiko Sato, Tamio Fujiwara
Antimicrob Agents Chemother. Jan 2015; 59(1): 397–406. Published online Dec 3, 2014. doi: 10.1128/AAC.03909-14
PMCID:
PMC4291378
Effect of Steady-State Faldaprevir on the Pharmacokinetics of Steady-State Methadone and Buprenorphine-Naloxone in Subjects Receiving Stable Addiction Management Therapy
David Joseph, Michael J. Schobelock, Robert R. Riesenberg, Bradley D. Vince, Lynn R. Webster, Abidemi Adeniji, Mabrouk Elgadi, Fenglei Huang
Antimicrob Agents Chemother. Jan 2015; 59(1): 498–504. Published online Nov 10, 2014. doi: 10.1128/AAC.04046-14
PMCID:
PMC4291392
Effect of the Hepatitis C Virus Protease Inhibitor Faldaprevir on the Pharmacokinetics of an Oral Contraceptive Containing Ethinylestradiol and Levonorgestrel in Healthy Female Volunteers
John P. Sabo, Benjamin Lang, Mabrouk Elgadi, Fenglei Huang
Antimicrob Agents Chemother. Jan 2015; 59(1): 514–519. Published online Nov 10, 2014. doi: 10.1128/AAC.03589-14
PMCID:
PMC4291440
Enhanced Efficacy of Cidofovir Combined with Vaccinia Immune Globulin in Treating Progressive Cutaneous Vaccinia Virus Infections in Immunosuppressed Hairless Mice
Donald F. Smee, Ashley Dagley, Brittney Downs, Joseph Hagloch, E. Bart Tarbet
Antimicrob Agents Chemother. Jan 2015; 59(1): 520–526. Published online Nov 10, 2014. doi: 10.1128/AAC.04289-14
PMCID:
PMC4291394
Antiviral Activity of a Single-Domain Antibody Immunotoxin Binding to Glycoprotein D of Herpes Simplex Virus 2
Eileen M. Geoghegan, Hong Zhang, Prashant J. Desai, Arya Biragyn, Richard B. Markham
Antimicrob Agents Chemother. Jan 2015; 59(1): 527–535. Published online Nov 10, 2014. doi: 10.1128/AAC.03818-14
PMCID:
PMC4291438
In Vitro Resistance Selection with Doravirine (MK-1439), a Novel Nonnucleoside Reverse Transcriptase Inhibitor with Distinct Mutation Development Pathways
Meizhen Feng, Deping Wang, Jay A. Grobler, Daria J. Hazuda, Michael D. Miller, Ming-Tain Lai
Antimicrob Agents Chemother. Jan 2015; 59(1): 590–598. Published online Nov 10, 2014. doi: 10.1128/AAC.04201-14
PMCID:
PMC4291404
In Vitro Antiviral Activity and Preclinical and Clinical Resistance Profile of Miravirsen, a Novel Anti-Hepatitis C Virus Therapeutic Targeting the Human Factor miR-122
Søren Ottosen, Todd B. Parsley, Lu Yang, Karin Zeh, Leen-Jan van Doorn, Eva van der Veer, Anneke K. Raney, Michael R. Hodges, Amy K. Patick
Antimicrob Agents Chemother. Jan 2015; 59(1): 599–608. Published online Nov 10, 2014. doi: 10.1128/AAC.04220-14
PMCID:
PMC4291405

Epidemiology and Surveillance

Seasonal Variation in Penicillin Use in Mexico and Brazil: Analysis of the Impact of Over-the-Counter Restrictions
Yared Santa-Ana-Tellez, Aukje K. Mantel-Teeuwisse, Hubert G. M. Leufkens, Veronika J. Wirtz
Antimicrob Agents Chemother. Jan 2015; 59(1): 105–110. Published online Oct 13, 2014. doi: 10.1128/AAC.03629-14
PMCID:
PMC4291337
Antibiotic Use before Chlamydia and Gonorrhea Genital and Extragenital Screening in the Sexually Transmitted Infection Clinical Setting
Nicole H. T. M. Dukers-Muijrers, Genevieve A. F. S. van Liere, Petra F. G. Wolffs, Casper Den Heijer, Marita I. L. S. Werner, Christian J. P. A. Hoebe
Antimicrob Agents Chemother. Jan 2015; 59(1): 121–128. Published online Oct 13, 2014. doi: 10.1128/AAC.03932-14
PMCID:
PMC4291339
Genomic Epidemiology of Klebsiella pneumoniae in Italy and Novel Insights into the Origin and Global Evolution of Its Resistance to Carbapenem Antibiotics
Stefano Gaiarsa, Francesco Comandatore, Paolo Gaibani, Marta Corbella, Claudia Dalla Valle, Sara Epis, Erika Scaltriti, Edoardo Carretto, Claudio Farina, Maria Labonia, Maria Paola Landini, Stefano Pongolini, Vittorio Sambri, Claudio Bandi, Piero Marone, Davide Sassera
Antimicrob Agents Chemother. Jan 2015; 59(1): 389–396. Published online Nov 3, 2014. doi: 10.1128/AAC.04224-14
PMCID:
PMC4291437
Efficacy of Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine for Treatment of Uncomplicated Malaria in Children in Zaire and Uíge Provinces, Angola
Mateusz M. Plucinski, Eldin Talundzic, Lindsay Morton, Pedro Rafael Dimbu, Aleixo Panzo Macaia, Filomeno Fortes, Ira Goldman, Naomi Lucchi, Gail Stennies, John R. MacArthur, Venkatachalam Udhayakumar
Antimicrob Agents Chemother. Jan 2015; 59(1): 437–443. Published online Nov 3, 2014. doi: 10.1128/AAC.04181-14
PMCID:
PMC4291383
Trends in Serotype Distribution and Antimicrobial Susceptibility in Salmonella enterica Isolates from Humans in Belgium, 2009 to 2013
Pieter-Jan Ceyssens, Wesley Mattheus, Raymond Vanhoof, Sophie Bertrand
Antimicrob Agents Chemother. Jan 2015; 59(1): 544–552. Published online Nov 10, 2014. doi: 10.1128/AAC.04203-14
PMCID:
PMC4291397
Carbapenem-Resistant Klebsiella pneumoniae Urinary Tract Infection following Solid Organ Transplantation
Kyle D. Brizendine, Sandra S. Richter, Eric D. Cober, David van Duin
Antimicrob Agents Chemother. Jan 2015; 59(1): 553–557. Published online Nov 10, 2014. doi: 10.1128/AAC.04284-14
PMCID:
PMC4291398
Identification of VIM-2-Producing Pseudomonas aeruginosa from Tanzania Is Associated with Sequence Types 244 and 640 and the Location of blaVIM-2 in a TniC Integron
Sabrina Moyo, Bjørg Haldorsen, Said Aboud, Bjørn Blomberg, Samuel Y. Maselle, Arnfinn Sundsfjord, Nina Langeland, Ørjan Samuelsen
Antimicrob Agents Chemother. Jan 2015; 59(1): 682–685. Published online Oct 20, 2014. doi: 10.1128/AAC.01436-13
PMCID:
PMC4291420
Association of Class 1 and 2 Integrons with Multidrug-Resistant Acinetobacter baumannii International Clones and Acinetobacter nosocomialis Isolates
Natacha Martins, Renata Cristina Picão, Sheila Adams-Sapper, Lee W. Riley, Beatriz Meurer Moreira
Antimicrob Agents Chemother. Jan 2015; 59(1): 698–701. Published online Oct 27, 2014. doi: 10.1128/AAC.02415-14
PMCID:
PMC4291415
Rodrigo E. Mendes, David J. Farrell, Helio S. Sader, Robert K. Flamm, Ronald N. Jones
Antimicrob Agents Chemother. Jan 2015; 59(1): 702–706. Published online Oct 27, 2014. doi: 10.1128/AAC.04052-14
PMCID:
PMC4291425

Experimental Therapeutics

Mass Balance, Metabolite Profile, and In Vitro-In Vivo Comparison of Clearance Pathways of Deleobuvir, a Hepatitis C Virus Polymerase Inhibitor
Lin-Zhi Chen, John P. Sabo, Elsy Philip, Lois Rowland, Yan Mao, Bachir Latli, Diane Ramsden, Debra A. Mandarino, Rucha S. Sane
Antimicrob Agents Chemother. Jan 2015; 59(1): 25–37. Published online Oct 13, 2014. doi: 10.1128/AAC.03861-14
PMCID:
PMC4291358
Impact on Resistance of the Use of Therapeutically Equivalent Generics: the Case of Ciprofloxacin
Carlos A. Rodriguez, Maria Agudelo, Andres F. Zuluaga, Omar Vesga
Antimicrob Agents Chemother. Jan 2015; 59(1): 53–58. Published online Oct 13, 2014. doi: 10.1128/AAC.03633-14
PMCID:
PMC4291395
Inhibition of Salmonella enterica Biofilm Formation Using Small-Molecule Adenosine Mimetics
Jacob A. Koopman, Joanna M. Marshall, Aditi Bhatiya, Tadesse Eguale, Jesse J. Kwiek, John S. Gunn
Antimicrob Agents Chemother. Jan 2015; 59(1): 76–84. Published online Oct 13, 2014. doi: 10.1128/AAC.03407-14
PMCID:
PMC4291424
Contribution of the Nitroimidazoles PA-824 and TBA-354 to the Activity of Novel Regimens in Murine Models of Tuberculosis
Rokeya Tasneen, Kathy Williams, Opokua Amoabeng, Austin Minkowski, Khisimuzi E. Mdluli, Anna M. Upton, Eric L. Nuermberger
Antimicrob Agents Chemother. Jan 2015; 59(1): 129–135. Published online Oct 20, 2014. doi: 10.1128/AAC.03822-14
PMCID:
PMC4291340
In Vitro and In Vivo Activities of the Nitroimidazole TBA-354 against Mycobacterium tuberculosis
A. M. Upton, S. Cho, T. J. Yang, Y. Kim, Y. Wang, Y. Lu, B. Wang, J. Xu, K. Mdluli, Z. Ma, S. G. Franzblau
Antimicrob Agents Chemother. Jan 2015; 59(1): 136–144. Published online Oct 20, 2014. doi: 10.1128/AAC.03823-14
PMCID:
PMC4291341
An Optimized Mouse Thigh Infection Model for Enterococci and Its Impact on Antimicrobial Pharmacodynamics
Carlos A. Rodriguez, Maria Agudelo, Javier M. Gonzalez, Omar Vesga, Andres F. Zuluaga
Antimicrob Agents Chemother. Jan 2015; 59(1): 233–238. Published online Oct 27, 2014. doi: 10.1128/AAC.02352-13
PMCID:
PMC4291355
Anti-Alpha-Toxin Monoclonal Antibody and Antibiotic Combination Therapy Improves Disease Outcome and Accelerates Healing in a Staphylococcus aureus Dermonecrosis Model
Jamese J. Hilliard, Vivekananda Datta, Christine Tkaczyk, Melissa Hamilton, Agnieszka Sadowska, Omari Jones-Nelson, Terrence O'Day, William J. Weiss, Szabolcs Szarka, Vien Nguyen, Laszlo Prokai, JoAnn Suzich, C. Kendall Stover, Bret R. Sellman
Antimicrob Agents Chemother. Jan 2015; 59(1): 299–309. Published online Oct 27, 2014. doi: 10.1128/AAC.03918-14
PMCID:
PMC4291365
Cationic Liposomal Sodium Stibogluconate (SSG), a Potent Therapeutic Tool for Treatment of Infection by SSG-Sensitive and -Resistant Leishmania donovani
Roma Sinha, Jayeeta Roychoudhury, Partha Palit, Nahid Ali
Antimicrob Agents Chemother. Jan 2015; 59(1): 344–355. Published online Nov 3, 2014. doi: 10.1128/AAC.03305-14
PMCID:
PMC4291371
A Chemical Rescue Screen Identifies a Plasmodium falciparum Apicoplast Inhibitor Targeting MEP Isoprenoid Precursor Biosynthesis
Wesley Wu, Zachary Herrera, Danny Ebert, Katie Baska, Seok H. Cho, Joseph L. DeRisi, Ellen Yeh
Antimicrob Agents Chemother. Jan 2015; 59(1): 356–364. Published online Nov 3, 2014. doi: 10.1128/AAC.03342-14
PMCID:
PMC4291372
Pharmacodynamic Evaluation of the Activities of Six Parenteral Vancomycin Products Available in the United States
Arnold Louie, Michael T. Boyne, II, Vikram Patel, Clayton Huntley, Weiguo Liu, Steven Fikes, Stephanie Kurhanewicz, Jaime Rodriquez, Nichole Robbins, David Brown, Dodge Baluya, G. L. Drusano
Antimicrob Agents Chemother. Jan 2015; 59(1): 622–632. Published online Nov 10, 2014. doi: 10.1128/AAC.03710-14
PMCID:
PMC4291350
Radioiodinated DPA-713 Imaging Correlates with Bactericidal Activity of Tuberculosis Treatments in Mice
Alvaro A. Ordonez, Supriya Pokkali, Vincent P. DeMarco, Mariah Klunk, Ronnie C. Mease, Catherine A. Foss, Martin G. Pomper, Sanjay K. Jain
Antimicrob Agents Chemother. Jan 2015; 59(1): 642–649. Published online Nov 17, 2014. doi: 10.1128/AAC.04180-14
PMCID:
PMC4291409
In Vitro Activity of wALADin Benzimidazoles against Different Life Cycle Stages of Plasmodium Parasites
Christian S. Lentz, Julia M. Sattler, Martina Fendler, Simon Gottwalt, Victoria S. Halls, Silke Strassel, Sandra Arriens, Jeffrey S. Hannam, Sabine Specht, Michael Famulok, Ann-Kristin Mueller, Achim Hoerauf, Kenneth M. Pfarr
Antimicrob Agents Chemother. Jan 2015; 59(1): 654–658. Published online Oct 13, 2014. doi: 10.1128/AAC.02383-14
PMCID:
PMC4291411
Antimalarial Activity of Granzyme B and Its Targeted Delivery by a Granzyme B–Single-Chain Fv Fusion Protein
Stephanie Kapelski, Melanie de Almeida, Rainer Fischer, Stefan Barth, Rolf Fendel
Antimicrob Agents Chemother. Jan 2015; 59(1): 669–672. Published online Oct 13, 2014. doi: 10.1128/AAC.04190-14
PMCID:
PMC4291407
Verapamil Increases the Bactericidal Activity of Bedaquiline against Mycobacterium tuberculosis in a Mouse Model
Shashank Gupta, Sandeep Tyagi, William R. Bishai
Antimicrob Agents Chemother. Jan 2015; 59(1): 673–676. Published online Oct 20, 2014. doi: 10.1128/AAC.04019-14
PMCID:
PMC4291418
The Investigational Agent E1210 Is Effective in Treatment of Experimental Invasive Candidiasis Caused by Resistant Candida albicans
Nathan P. Wiederhold, Laura K. Najvar, Annette W. Fothergill, Dora I. McCarthy, Rosie Bocanegra, Marcos Olivo, William R. Kirkpatrick, Michael P. Everson, Frederick P. Duncanson, Thomas F. Patterson
Antimicrob Agents Chemother. Jan 2015; 59(1): 690–692. Published online Oct 20, 2014. doi: 10.1128/AAC.03944-14
PMCID:
PMC4291422

Clinical Therapeutics

Impact of Nonlinear Interactions of Pharmacokinetics and MICs on Sputum Bacillary Kill Rates as a Marker of Sterilizing Effect in Tuberculosis
Emmanuel Chigutsa, Jotam G. Pasipanodya, Marianne E. Visser, Paul D. van Helden, Peter J. Smith, Frederick A. Sirgel, Tawanda Gumbo, Helen McIlleron
Antimicrob Agents Chemother. Jan 2015; 59(1): 38–45. Published online Oct 13, 2014. doi: 10.1128/AAC.03931-14
PMCID:
PMC4291375
Antibiotic-Loaded Synthetic Calcium Sulfate Beads for Prevention of Bacterial Colonization and Biofilm Formation in Periprosthetic Infections
R. P. Howlin, M. J. Brayford, J. S. Webb, J. J. Cooper, S. S. Aiken, P. Stoodley
Antimicrob Agents Chemother. Jan 2015; 59(1): 111–120. Published online Oct 13, 2014. doi: 10.1128/AAC.03676-14
PMCID:
PMC4291338
Anna C. Nilsson, Håkan Janson, Hedda Wold, Anders Fugelli, Karin Andersson, Camilla Håkangård, Pernilla Olsson, Wenche Marie Olsen
Antimicrob Agents Chemother. Jan 2015; 59(1): 145–151. Published online Oct 20, 2014. doi: 10.1128/AAC.03513-14
PMCID:
PMC4291342
A Hybrid Cationic Peptide Composed of Human β-Defensin-1 and Humanized θ-Defensin Sequences Exhibits Salt-Resistant Antimicrobial Activity
Sudar Olli, Ramakrishnan Nagaraj, Swapna R. Motukupally
Antimicrob Agents Chemother. Jan 2015; 59(1): 217–225. Published online Oct 27, 2014. doi: 10.1128/AAC.03901-14
PMCID:
PMC4291353
Stratification of the Impact of Inappropriate Empirical Antimicrobial Therapy for Gram-Negative Bloodstream Infections by Predicted Prognosis
Sarah E. Cain, Joseph Kohn, P. Brandon Bookstaver, Helmut Albrecht, Majdi N. Al-Hasan
Antimicrob Agents Chemother. Jan 2015; 59(1): 245–250. Published online Oct 27, 2014. doi: 10.1128/AAC.03935-14
PMCID:
PMC4291357
Population Pharmacokinetics of Gentamicin and Dosing Optimization for Infants
Susanna E. Medellín-Garibay, Aída Rueda-Naharro, Silvia Peña-Cabia, Benito García, Silvia Romano-Moreno, Emilia Barcia
Antimicrob Agents Chemother. Jan 2015; 59(1): 482–489. Published online Nov 10, 2014. doi: 10.1128/AAC.03464-14
PMCID:
PMC4291441
Pharmacokinetics, Microbial Response, and Pulmonary Outcomes of Multidose Intravenous Azithromycin in Preterm Infants at Risk for Ureaplasma Respiratory Colonization
L. Marcela Merchan, Hazem E. Hassan, Michael L. Terrin, Ken B. Waites, David A. Kaufman, Namasivayam Ambalavanan, Pamela Donohue, Susan J. Dulkerian, Robert Schelonka, Laurence S. Magder, Sagar Shukla, Natalie D. Eddington, Rose M. Viscardi
Antimicrob Agents Chemother. Jan 2015; 59(1): 570–578. Published online Nov 10, 2014. doi: 10.1128/AAC.03951-14
PMCID:
PMC4291400
Effect of Rifampin and Rifabutin on Serum Itraconazole Levels in Patients with Chronic Pulmonary Aspergillosis and Coexisting Nontuberculous Mycobacterial Infection
Seong Mi Moon, Hye Yun Park, Byeong-Ho Jeong, Kyeongman Jeon, Soo-Youn Lee, Won-Jung Koh
Antimicrob Agents Chemother. Jan 2015; 59(1): 663–665. Published online Oct 13, 2014. doi: 10.1128/AAC.04075-14
PMCID:
PMC4291413
Arthritis and Benznidazole: More Closely Related than We Thought
E. Aldasoro, M. J. Pinazo, I. Oliveira, J. Munoz, E. Posada, A. Requena-Méndez, N. Serret, J. Gascon
Antimicrob Agents Chemother. Jan 2015; 59(1): 727–729. Published online Nov 10, 2014. doi: 10.1128/AAC.04078-14
PMCID:
PMC4291430

Pharmacology

Colistin Pharmacokinetics in Burn Patients during Continuous Venovenous Hemofiltration
Kevin S. Akers, Matthew P. Rowan, Krista L. Niece, Ian J. Stewart, Katrin Mende, Jason M. Cota, Clinton K. Murray, Kevin K. Chung
Antimicrob Agents Chemother. Jan 2015; 59(1): 46–52. Published online Oct 13, 2014. doi: 10.1128/AAC.03783-14
PMCID:
PMC4291386
Pharmacokinetics of Injectable, Long-Acting Nevirapine for HIV Prophylaxis in Breastfeeding Infants
John M. Cortez, Jr., Rafaela Quintero, John A. Moss, Martin Beliveau, Thomas J. Smith, Marc M. Baum
Antimicrob Agents Chemother. Jan 2015; 59(1): 59–66. Published online Oct 13, 2014. doi: 10.1128/AAC.03906-14
PMCID:
PMC4291403
Continuous versus Short-Term Infusion of Cefuroxime: Assessment of Concept Based on Plasma, Subcutaneous Tissue, and Bone Pharmacokinetics in an Animal Model
Mikkel Tøttrup, Bo M. Bibby, Tore F. Hardlei, Mats Bue, Sigrid Kerrn-Jespersen, Kurt Fuursted, Kjeld Søballe, Hanne Birke-Sørensen
Antimicrob Agents Chemother. Jan 2015; 59(1): 67–75. Published online Oct 13, 2014. doi: 10.1128/AAC.03857-14
PMCID:
PMC4291408
Carboxymefloquine, the Major Metabolite of the Antimalarial Drug Mefloquine, Induces Drug-Metabolizing Enzyme and Transporter Expression by Activation of Pregnane X Receptor
Rita Piedade, Stefanie Traub, Andreas Bitter, Andreas K. Nüssler, José P. Gil, Matthias Schwab, Oliver Burk
Antimicrob Agents Chemother. Jan 2015; 59(1): 96–104. Published online Oct 13, 2014. doi: 10.1128/AAC.04140-14
PMCID:
PMC4291335
Activities of Antibiotic Combinations against Resistant Strains of Pseudomonas aeruginosa in a Model of Infected THP-1 Monocytes
Julien M. Buyck, Paul M. Tulkens, Françoise Van Bambeke
Antimicrob Agents Chemother. Jan 2015; 59(1): 258–268. Published online Oct 27, 2014. doi: 10.1128/AAC.04011-14
PMCID:
PMC4291360
Population Pharmacokinetic Analyses for BC-3781 Using Phase 2 Data from Patients with Acute Bacterial Skin and Skin Structure Infections
C. M. Rubino, B. Xue, S. M. Bhavnani, W. T. Prince, Z. Ivezic-Schoenfeld, W. W. Wicha, P. G. Ambrose
Antimicrob Agents Chemother. Jan 2015; 59(1): 282–288. Published online Oct 27, 2014. doi: 10.1128/AAC.02033-13
PMCID:
PMC4291363
Pharmacokinetic-Pharmacodynamic Analysis for Efficacy of Ceftaroline Fosamil in Patients with Acute Bacterial Skin and Skin Structure Infections
Sujata M. Bhavnani, Jeffrey P. Hammel, Scott A. Van Wart, Christopher M. Rubino, Daniel K. Reynolds, Alan Forrest, George L. Drusano, Tatiana Khariton, H. David Friedland, Todd A. Riccobene, Paul G. Ambrose
Antimicrob Agents Chemother. Jan 2015; 59(1): 372–380. Published online Nov 3, 2014. doi: 10.1128/AAC.02531-14
PMCID:
PMC4291374
Novel Rate-Area-Shape Modeling Approach To Quantify Bacterial Killing and Regrowth for In Vitro Static Time-Kill Studies
Soon-Ee Cheah, Jian Li, Roger L. Nation, Jürgen B. Bulitta
Antimicrob Agents Chemother. Jan 2015; 59(1): 381–388. Published online Nov 3, 2014. doi: 10.1128/AAC.04182-14
PMCID:
PMC4291376
Podjanee Jittamala, Sasithon Pukrittayakamee, Elizabeth A. Ashley, François Nosten, Borimas Hanboonkunupakarn, Sue J. Lee, Praiya Thana, Kalayanee Chairat, Daniel Blessborn, Salwaluk Panapipat, Nicholas J. White, Nicholas P. J. Day, Joel Tarning
Antimicrob Agents Chemother. Jan 2015; 59(1): 505–513. Published online Nov 10, 2014. doi: 10.1128/AAC.03829-14
PMCID:
PMC4291381
Lycopene Attenuates Colistin-Induced Nephrotoxicity in Mice via Activation of the Nrf2/HO-1 Pathway
Chongshan Dai, Shusheng Tang, Sijun Deng, Shen Zhang, Yan Zhou, Tony Velkov, Jian Li, Xilong Xiao
Antimicrob Agents Chemother. Jan 2015; 59(1): 579–585. Published online Nov 10, 2014. doi: 10.1128/AAC.03925-14
PMCID:
PMC4291401

Letters to the Editor

Testing of Middle East Respiratory Syndrome Coronavirus Replication Inhibitors for the Ability To Block Viral Entry
Qi Liu, Shuai Xia, Zhiwu Sun, Qian Wang, Lanying Du, Lu Lu, Shibo Jiang
Antimicrob Agents Chemother. Jan 2015; 59(1): 742–744. Published online Oct 20, 2014. doi: 10.1128/AAC.03977-14
PMCID:
PMC4291393
Emergence of OXA-48-Producing Escherichia coli Clone ST38 in Fowl
Charbel Al Bayssari, Abiola Olumuyiwa Olaitan, Fouad Dabboussi, Monzer Hamze, Jean-Marc Rolain
Antimicrob Agents Chemother. Jan 2015; 59(1): 745–746. Published online Oct 27, 2014. doi: 10.1128/AAC.03552-14
PMCID:
PMC4291434
Analyses of Multidrug Efflux Pump-Like Proteins Encoded on the Staphylococcus aureus Chromosome
Bryan D. Schindler, Emmanuel Frempong-Manso, Carmen E. DeMarco, Christos Kosmidis, Varun Matta, Susan M. Seo, Glenn W. Kaatz
Antimicrob Agents Chemother. Jan 2015; 59(1): 747–748. Published online Nov 17, 2014. doi: 10.1128/AAC.04678-14
PMCID:
PMC4291402
Insight into the Role of Chlorhexidine in Delftia acidovorans Biofilm Formation
Carlos Henrique Camargo, Ariane Bruder-Nascimento
Antimicrob Agents Chemother. Jan 2015; 59(1): 749. Published online Dec 23, 2014. doi: 10.1128/AAC.04008-14
PMCID:
PMC4291443
Simple Solutions Reflect Misunderstanding of Animal Antibiotic Use
Richard Carnevale
Antimicrob Agents Chemother. Jan 2015; 59(1): 750. Published online Dec 23, 2014. doi: 10.1128/AAC.04451-14
PMCID:
PMC4291416
Reply to “Simple Solutions Reflect Misunderstanding of Animal Antibiotic Use”
Matthew Metz, David M. Shlaes
Antimicrob Agents Chemother. Jan 2015; 59(1): 751. Published online Dec 23, 2014. doi: 10.1128/AAC.04604-14
PMCID:
PMC4291435

Masthead

Editorial Board
Antimicrob Agents Chemother. Jan 2015; 59(1): A1. Published online Dec 23, 2014. doi: 10.1128/AAC.masthead.59-1
PMCID:
PMC4291423

Articles from Antimicrobial Agents and Chemotherapy are provided here courtesy of American Society for Microbiology (ASM)