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Commentaries Marketing data: Has the rise of impact factor led to the fall of objective language in the scientific article? Véronique J Fraser and James G Martin Respir Res. 2009; 10(1): 35. Published online 2009 May 11. doi: 10.1186/1465-9921-10-35.PMCID: PMC2685417 Reporting and evaluating genetic association studies Stephen P Peters Respir Res. 2009; 10(1): 109. Published online 2009 November 12. doi: 10.1186/1465-9921-10-109.PMCID: PMC2780405 Reviews EAACI position paper on occupational rhinitis Gianna Moscato, Olivier Vandenplas, Roy Gerth Van Wijk, Jean-Luc Malo, Luca Perfetti, Santiago Quirce, Jolanta Walusiak, Roberto Castano, Gianni Pala, Denyse Gautrin, Hans De Groot, Ilenia Folletti, Mona Rita Yacoub, and Andrea Siracusa Respir Res. 2009; 10(1): 16. Published online 2009 March 3. doi: 10.1186/1465-9921-10-16.PMCID: PMC2654869 Mechanisms of the noxious inflammatory cycle in cystic fibrosis Mathilde Rottner, Jean-Marie Freyssinet, and M Carmen Martínez Respir Res. 2009; 10(1): 23. Published online 2009 March 13. doi: 10.1186/1465-9921-10-23.PMCID: PMC2660284 Systems biology coupled with label-free high-throughput detection as a novel approach for diagnosis of chronic obstructive pulmonary disease Joanna L Richens, Richard A Urbanowicz, Elizabeth AM Lunt, Rebecca Metcalf, Jonathan Corne, Lucy Fairclough, and Paul O'Shea Respir Res. 2009; 10(1): 29. Published online 2009 April 22. doi: 10.1186/1465-9921-10-29.PMCID: PMC2678087 Diet and asthma: looking back, moving forward June-Ho Kim, Philippa E Ellwood, and M Innes Asher Respir Res. 2009; 10(1): 49. Published online 2009 June 12. doi: 10.1186/1465-9921-10-49.PMCID: PMC2703624 Alveolar hypoxia, alveolar macrophages, and systemic inflammation Jie Chao, John G Wood, and Norberto C Gonzalez Respir Res. 2009; 10(1): 54. Published online 2009 June 22. doi: 10.1186/1465-9921-10-54.PMCID: PMC2705912 Does unrestrained single-chamber plethysmography provide a valid assessment of airway responsiveness in allergic BALB/c mice? Qingling Zhang, Kefang Lai, Jiaxing Xie, Guoqin Chen, and Nanshan Zhong Respir Res. 2009; 10(1): 61. Published online 2009 July 3. doi: 10.1186/1465-9921-10-61.PMCID: PMC2719610 Endothelial cells and pulmonary arterial hypertension: apoptosis, proliferation, interaction and transdifferentiation Seiichiro Sakao, Koichiro Tatsumi, and Norbert F Voelkel Respir Res. 2009; 10(1): 95. Published online 2009 October 13. doi: 10.1186/1465-9921-10-95.PMCID: PMC2768704 Research BODE index versus GOLD classification for explaining anxious and depressive symptoms in patients with COPD – a cross-sectional study Georg-Christian Funk, Kathrin Kirchheiner, Otto Chris Burghuber, and Sylvia Hartl Respir Res. 2009; 10(1): 1. Published online 2009 January 9. doi: 10.1186/1465-9921-10-1.PMCID: PMC2626579 Transcriptome profiling of primary murine monocytes, lung macrophages and lung dendritic cells reveals a distinct expression of genes involved in cell trafficking Zbigniew Zasłona, Jochen Wilhelm, Lidija Cakarova, Leigh M Marsh, Werner Seeger, Jürgen Lohmeyer, and Werner von Wulffen Respir Res. 2009; 10(1): 2. Published online 2009 January 16. doi: 10.1186/1465-9921-10-2.PMCID: PMC2639356 Nitric oxide gas phase release in human small airway epithelial cells Jingjing Jiang, Nikita Malavia, Vinod Suresh, and Steven C George Respir Res. 2009; 10(1): 3. Published online 2009 January 19. doi: 10.1186/1465-9921-10-3.PMCID: PMC2633284 Comparison of mannitol and methacholine to predict exercise-induced bronchoconstriction and a clinical diagnosis of asthma Sandra D Anderson, Brett Charlton, John M Weiler, Sara Nichols, Sheldon L Spector, David S Pearlman, and A305 Study Group Respir Res. 2009; 10(1): 4. Published online 2009 January 23. doi: 10.1186/1465-9921-10-4.PMCID: PMC2644668 Impact of interleukin-6 on hypoxia-induced pulmonary hypertension and lung inflammation in mice Laurent Savale, Ly Tu, Dominique Rideau, Mohamed Izziki, Bernard Maitre, Serge Adnot, and Saadia Eddahibi Respir Res. 2009; 10(1): 6. Published online 2009 January 27. doi: 10.1186/1465-9921-10-6.PMCID: PMC2644669 Exercise intolerance and systemic manifestations of pulmonary emphysema in a mouse model Lars Lüthje, Tobias Raupach, Hellmuth Michels, Bernhard Unsöld, Gerd Hasenfuss, Harald Kögler, and Stefan Andreas Respir Res. 2009; 10(1): 7. Published online 2009 January 28. doi: 10.1186/1465-9921-10-7.PMCID: PMC2644670 Calcitonin gene-related peptide stimulates proliferation of alveolar epithelial cells Yukiko Kawanami, Yasuo Morimoto, Heungnam Kim, Takehiro Nakamura, Kazuhiko Machida, Takashi Kido, Etsuko Asonuma, Kazuhiro Yatera, Chiharu Yoshii, and Masamitsu Kido Respir Res. 2009; 10(1): 8. Published online 2009 February 3. doi: 10.1186/1465-9921-10-8.PMCID: PMC2651852 Mechanical compression attenuates normal human bronchial epithelial wound healing Stephen P Arold, Nikita Malavia, and Steven C George Respir Res. 2009; 10(1): 9. Published online 2009 February 12. doi: 10.1186/1465-9921-10-9.PMCID: PMC2672070 Pneumocystis murina colonization in immunocompetent surfactant protein A deficient mice following environmental exposure Michael J Linke, Alan D Ashbaugh, Jeffery A Demland, and Peter D Walzer Respir Res. 2009; 10(1): 10. Published online 2009 February 19. doi: 10.1186/1465-9921-10-10.PMCID: PMC2650685 Budesonide/formoterol as effective as prednisolone plus formoterol in acute exacerbations of COPD A double-blind, randomised, non-inferiority, parallel-group, multicentre study Björn Ställberg, Olof Selroos, Claus Vogelmeier, Eva Andersson, Tommy Ekström, and Kjell Larsson Respir Res. 2009; 10(1): 11. Published online 2009 February 19. doi: 10.1186/1465-9921-10-11.PMCID: PMC2653467 The effect of tiotropium therapy on markers of elastin degradation in COPD Shuren Ma, Yong Y Lin, Lori Tartell, and Gerard M Turino Respir Res. 2009; 10(1): 12. Published online 2009 February 25. doi: 10.1186/1465-9921-10-12.PMCID: PMC2682791 Activated mammalian target of rapamycin is associated with T regulatory cell insufficiency in nasal polyps Geng Xu, Jiahong Xia, Xiaoyang Hua, Han Zhou, Chuanzhao Yu, Zheng Liu, Kemin Cai, Jianbo Shi, and Huabin Li Respir Res. 2009; 10(1): 13. Published online 2009 February 27. doi: 10.1186/1465-9921-10-13.PMCID: PMC2651851 Down-regulation of the inhibitor of growth family member 4 (ING4) in different forms of pulmonary fibrosis Argyris Tzouvelekis, Vassilis Aidinis, Vagelis Harokopos, Andreas Karameris, George Zacharis, Dimitrios Mikroulis, Fotios Konstantinou, Paschalis Steiropoulos, Ioannis Sotiriou, Marios Froudarakis, Ioannis Pneumatikos, Rodoula Tringidou, and Demosthenes Bouros Respir Res. 2009; 10(1): 14. Published online 2009 February 27. doi: 10.1186/1465-9921-10-14.PMCID: PMC2662808 Diagnosing asthma in general practice with portable exhaled nitric oxide measurement – results of a prospective diagnostic study Antonius Schneider, Lisa Tilemann, Tjard Schermer, Lena Gindner, Gunter Laux, Joachim Szecsenyi, and Franz Joachim Meyer Respir Res. 2009; 10(1): 15. Published online 2009 March 3. doi: 10.1186/1465-9921-10-15.PMCID: PMC2660901 Hypoxia regulates human lung fibroblast proliferation via p53-dependent and -independent pathways Shiro Mizuno, Herman J Bogaard, Norbert F Voelkel, Yukihiro Umeda, Maiko Kadowaki, Shingo Ameshima, Isamu Miyamori, and Takeshi Ishizaki Respir Res. 2009; 10(1): 17. Published online 2009 March 6. doi: 10.1186/1465-9921-10-17.PMCID: PMC2663549 Synthetic RGDS peptide attenuates lipopolysaccharide-induced pulmonary inflammation by inhibiting integrin signaled MAP kinase pathways Changsuk Moon, Jeong Ran Han, Hyun-Jung Park, Jong Sik Hah, and Jihee Lee Kang Respir Res. 2009; 10(1): 18. Published online 2009 March 9. doi: 10.1186/1465-9921-10-18.PMCID: PMC2666640 Early biomarkers and potential mediators of ventilation-induced lung injury in very preterm lambs Megan J Wallace, Megan E Probyn, Valerie A Zahra, Kelly Crossley, Timothy J Cole, Peter G Davis, Colin J Morley, and Stuart B Hooper Respir Res. 2009; 10(1): 19. Published online 2009 March 10. doi: 10.1186/1465-9921-10-19.PMCID: PMC2662809 Novel autoantigens immunogenic in COPD patients Petra Leidinger, Andreas Keller, Sabrina Heisel, Nicole Ludwig, Stefanie Rheinheimer, Veronika Klein, Claudia Andres, Jürg Hamacher, Hanno Huwer, Bernhard Stephan, Ingo Stehle, Hans-Peter Lenhof, and Eckart Meese Respir Res. 2009; 10(1): 20. Published online 2009 March 12. doi: 10.1186/1465-9921-10-20.PMCID: PMC2667165 Adam33 polymorphisms are associated with COPD and lung function in long-term tobacco smokers Alireza Sadeghnejad, Jill A Ohar, Siqun L Zheng, David A Sterling, Gregory A Hawkins, Deborah A Meyers, and Eugene R Bleecker Respir Res. 2009; 10(1): 21. Published online 2009 March 12. doi: 10.1186/1465-9921-10-21.PMCID: PMC2664793 Particles induce apical plasma membrane enlargement in epithelial lung cell line depending on particle surface area dose Christina Brandenberger, Barbara Rothen-Rutishauser, Fabian Blank, Peter Gehr, and Christian Mühlfeld Respir Res. 2009; 10(1): 22. Published online 2009 March 12. doi: 10.1186/1465-9921-10-22.PMCID: PMC2661036 Dysregulated apoptosis and NFκB expression in COPD subjects Vanessa Brown, J Stuart Elborn, Judy Bradley, and Madeleine Ennis Respir Res. 2009; 10(1): 24. Published online 2009 March 18. doi: 10.1186/1465-9921-10-24.PMCID: PMC2667166 Ascorbic acid pre-treated quartz stimulates TNF-α release in RAW 264.7 murine macrophages through ROS production and membrane lipid peroxidation Sonia Scarfì, Mirko Magnone, Chiara Ferraris, Marina Pozzolini, Federica Benvenuto, Umberto Benatti, and Marco Giovine Respir Res. 2009; 10(1): 25. Published online 2009 March 19. doi: 10.1186/1465-9921-10-25.PMCID: PMC2662810 Influence of the cystic fibrosis transmembrane conductance regulator on expression of lipid metabolism-related genes in dendritic cells Yaqin Xu, Christine Tertilt, Anja Krause, Luis EN Quadri, Ronald G Crystal, and Stefan Worgall Respir Res. 2009; 10(1): 26. Published online 2009 April 3. doi: 10.1186/1465-9921-10-26.PMCID: PMC2683168 Vascular Endothelial Growth Factor (VEGF) isoform expression and activity in human and murine lung injury Andrew RL Medford, Samantha K Douglas, Sofia IH Godinho, Kay M Uppington, Lynne Armstrong, Kathleen M Gillespie, Berendine van Zyl, Terry D Tetley, Nassif BN Ibrahim, and Ann B Millar Respir Res. 2009; 10(1): 27. Published online 2009 April 9. doi: 10.1186/1465-9921-10-27.PMCID: PMC2674417 Exhaled nitric oxide in a population-based study of Southern California Schoolchildren William S Linn, Edward B Rappaport, Kiros T Berhane, Tracy M Bastain, Edward L Avol, and Frank D Gilliland Respir Res. 2009; 10(1): 28. Published online 2009 April 21. doi: 10.1186/1465-9921-10-28.PMCID: PMC2678086 Sildenafil attenuates pulmonary inflammation and fibrin deposition, mortality and right ventricular hypertrophy in neonatal hyperoxic lung injury Yvonne P de Visser, Frans J Walther, El Houari Laghmani, Hester Boersma, Arnoud van der Laarse, and Gerry TM Wagenaar Respir Res. 2009; 10(1): 30. Published online 2009 April 29. doi: 10.1186/1465-9921-10-30.PMCID: PMC2681457 Extracellular Hsp72, an endogenous DAMP, is released by virally infected airway epithelial cells and activates neutrophils via Toll-like receptor (TLR)-4 Derek S Wheeler, Margaret A Chase, Albert P Senft, Sue E Poynter, Hector R Wong, and Kristen Page Respir Res. 2009; 10(1): 31. Published online 2009 April 30. doi: 10.1186/1465-9921-10-31.PMCID: PMC2679007 Simvastatin ameliorates established pulmonary hypertension through a heme oxygenase-1 dependent pathway in rats Hsao-Hsun Hsu, Wen-Je Ko, Jo-Yu Hsu, Jin-Shing Chen, Yung-Chie Lee, I-Rue Lai, and Chau-Fong Chen Respir Res. 2009; 10(1): 32. Published online 2009 May 2. doi: 10.1186/1465-9921-10-32.PMCID: PMC2681458 Macrophage CD74 contributes to MIF-induced pulmonary inflammation Koichiro Takahashi, Kiyokazu Koga, Helena M Linge, Yinzhong Zhang, Xinchun Lin, Christine N Metz, Yousef Al-Abed, Kaie Ojamaa, and Edmund J Miller Respir Res. 2009; 10(1): 33. Published online 2009 May 4. doi: 10.1186/1465-9921-10-33.PMCID: PMC2681459 Adult onset lung disease following transient disruption of fetal stretch-induced differentiation Joseph J Hudak, Erin Killeen, Ashok Chandran, J Craig Cohen, and Janet E Larson Respir Res. 2009; 10(1): 34. Published online 2009 May 6. doi: 10.1186/1465-9921-10-34.PMCID: PMC2685416 Silencing CD36 gene expression results in the inhibition of latent-TGF-β1 activation and suppression of silica-induced lung fibrosis in the rat Xin Wang, Ying Chen, Lina Lv, and Jie Chen Respir Res. 2009; 10(1): 36. Published online 2009 May 13. doi: 10.1186/1465-9921-10-36.PMCID: PMC2698900 Role of the tachykinin NK1 receptor in a murine model of cigarette smoke-induced pulmonary inflammation Katelijne O De Swert, Ken R Bracke, Tine Demoor, Guy G Brusselle, and Guy F Joos Respir Res. 2009; 10(1): 37. Published online 2009 May 15. doi: 10.1186/1465-9921-10-37.PMCID: PMC2689186 N-α-PGP and PGP, potential biomarkers and therapeutic targets for COPD Philip O'Reilly, Patricia L Jackson, Brett Noerager, Suzanne Parker, Mark Dransfield, Amit Gaggar, and J Edwin Blalock Respir Res. 2009; 10(1): 38. Published online 2009 May 18. doi: 10.1186/1465-9921-10-38.PMCID: PMC2693492 A multi-target antisense approach against PDE4 and PDE7 reduces smoke-induced lung inflammation in mice Marylène Fortin, Hélène D'Anjou, Marie-Ève Higgins, Jasmine Gougeon, Paméla Aubé, Kamel Moktefi, Sonia Mouissi, Serge Séguin, Rosanne Séguin, Paolo M Renzi, Luc Paquet, and Nicolay Ferrari Respir Res. 2009; 10(1): 39. Published online 2009 May 20. doi: 10.1186/1465-9921-10-39.PMCID: PMC2696437 Expression of transforming growth factor-β (TGF-β) in chronic idiopathic cough Shaoping Xie, Patricia Macedo, Mark Hew, Christina Nassenstein, Kang-Yun Lee, and Kian Fan Chung Respir Res. 2009; 10(1): 40. Published online 2009 May 22. doi: 10.1186/1465-9921-10-40.PMCID: PMC2688489 COPD phenotype description using principal components analysis Kay Roy, Jacky Smith, Umme Kolsum, Zöe Borrill, Jørgen Vestbo, and Dave Singh Respir Res. 2009; 10(1): 41. Published online 2009 May 29. doi: 10.1186/1465-9921-10-41.PMCID: PMC2698901 Altered expression of T cell Immunoglobulin-Mucin (TIM) molecules in bronchoalveolar lavage CD4+ T cells in sarcoidosis Farah Idali, Jan Wahlström, Benita Dahlberg, Mohsen Khademi, Tomas Olsson, Anders Eklund, and Johan Grunewald Respir Res. 2009; 10(1): 42. Published online 2009 May 29. doi: 10.1186/1465-9921-10-42.PMCID: PMC2694180 Long-term activation of TLR3 by Poly(I:C) induces inflammation and impairs lung function in mice Nicole C Stowell, Jonathan Seideman, Holly A Raymond, Karen A Smalley, Roberta J Lamb, Devon D Egenolf, Peter J Bugelski, Lynne A Murray, Paul A Marsters, Rachel A Bunting, Richard A Flavell, Lena Alexopoulou, Lani R San Mateo, Don E Griswold, Robert T Sarisky, M Lamine Mbow, and Anuk M Das Respir Res. 2009; 10(1): 43. Published online 2009 June 1. doi: 10.1186/1465-9921-10-43.PMCID: PMC2694181 Cyclic hydrostatic pressure and cotton particles stimulate synthesis by human lung macrophages of cytokines in vitro Sarah Lewis, Dave Singh, and Carol E Evans Respir Res. 2009; 10(1): 44. Published online 2009 June 2. doi: 10.1186/1465-9921-10-44.PMCID: PMC2708140 Impact of statins and ACE inhibitors on mortality after COPD exacerbations Eric M Mortensen, Laurel A Copeland, Mary Jo V Pugh, Marcos I Restrepo, Rosa Malo de Molina, Brandy Nakashima, and Antonio Anzueto Respir Res. 2009; 10(1): 45. Published online 2009 June 3. doi: 10.1186/1465-9921-10-45.PMCID: PMC2697974 Specific mediator inhibition by the NO donors SNP and NCX 2057 in the peripheral lung: implications for allergen-induced bronchoconstriction Anna-Karin Larsson, Magnus Bäck, Jon O Lundberg, and Sven-Erik Dahlén Respir Res. 2009; 10(1): 46. Published online 2009 June 4. doi: 10.1186/1465-9921-10-46.PMCID: PMC2696438 Cigarette smoke attenuates the production of cytokines by human plasmacytoid dendritic cells and enhances the release of IL-8 in response to TLR-9 stimulation Esmaeil Mortaz, Zsofia Lazar, Leo Koenderman, Aletta D Kraneveld, Frans P Nijkamp, and Gert Folkerts Respir Res. 2009; 10(1): 47. Published online 2009 June 10. doi: 10.1186/1465-9921-10-47.PMCID: PMC2701931 Inhaled steroid/tobacco smoke particle interactions: a new light on steroid resistance Giovanni Invernizzi, Ario Ruprecht, Cinzia De Marco, Roberto Mazza, Gabriele Nicolini, and Roberto Boffi Respir Res. 2009; 10(1): 48. Published online 2009 June 11. doi: 10.1186/1465-9921-10-48.PMCID: PMC2703623 Oxidative stress augments toll-like receptor 8 mediated neutrophilic responses in healthy subjects Satoru Yanagisawa, Akira Koarai, Hisatoshi Sugiura, Tomohiro Ichikawa, Masae Kanda, Rie Tanaka, Keiichiro Akamatsu, Tsunahiko Hirano, Kazuto Matsunaga, Yoshiaki Minakata, and Masakazu Ichinose Respir Res. 2009; 10(1): 50. Published online 2009 June 15. doi: 10.1186/1465-9921-10-50.PMCID: PMC2704194 Ag85B DNA vaccine suppresses airway inflammation in a murine model of asthma Jian Wu, Jun Xu, Chuang Cai, Xinglin Gao, Li Li, and Nanshan Zhong Respir Res. 2009; 10(1): 51. Published online 2009 June 16. doi: 10.1186/1465-9921-10-51.PMCID: PMC2713210 Control of allergic rhinitis and asthma test – a formal approach to the development of a measuring tool Luis Nogueira-Silva, Sonia V Martins, Ricardo Cruz-Correia, Luis F Azevedo, Mario Morais-Almeida, António Bugalho-Almeida, Marianela Vaz, Altamiro Costa-Pereira, and Joao A Fonseca Respir Res. 2009; 10(1): 52. Published online 2009 June 17. doi: 10.1186/1465-9921-10-52.PMCID: PMC2706215 Altered effector function of peripheral cytotoxic cells in COPD Richard A Urbanowicz, Jonathan R Lamb, Ian Todd, Jonathan M Corne, and Lucy C Fairclough Respir Res. 2009; 10(1): 53. Published online 2009 June 22. doi: 10.1186/1465-9921-10-53.PMCID: PMC2705911 Blockade of advanced glycation end product formation attenuates bleomycin-induced pulmonary fibrosis in rats Lei Chen, Tao Wang, Xun Wang, Bei-Bei Sun, Ji-Qiong Li, Dai-Shun Liu, Shang-Fu Zhang, Lin Liu, Dan Xu, Ya-Juan Chen, and Fu-Qiang Wen Respir Res. 2009; 10(1): 55. Published online 2009 June 24. doi: 10.1186/1465-9921-10-55.PMCID: PMC2712463 Soy consumption and risk of COPD and respiratory symptoms: a case-control study in Japan Fumi Hirayama, Andy H Lee, Colin W Binns, Yun Zhao, Tetsuo Hiramatsu, Yoshimasa Tanikawa, Koichi Nishimura, and Hiroyuki Taniguchi Respir Res. 2009; 10(1): 56. Published online 2009 June 26. doi: 10.1186/1465-9921-10-56.PMCID: PMC2708141 Lymphocyte apoptosis in murine Pneumocystis pneumonia Xin Shi, Nicole J LeCapitaine, Xiaowen L Rudner, Sanbao Ruan, and Judd E Shellito Respir Res. 2009; 10(1): 57. Published online 2009 June 26. doi: 10.1186/1465-9921-10-57.PMCID: PMC2714500 Protection from pulmonary ischemia-reperfusion injury by adenosine A2A receptor activation Ashish K Sharma, Joel Linden, Irving L Kron, and Victor E Laubach Respir Res. 2009; 10(1): 58. Published online 2009 June 26. doi: 10.1186/1465-9921-10-58.PMCID: PMC2711962 Efficacy of salmeterol/fluticasone propionate by GOLD stage of chronic obstructive pulmonary disease: analysis from the randomised, placebo-controlled TORCH study Christine R Jenkins, Paul W Jones, Peter MA Calverley, Bartolome Celli, Julie A Anderson, Gary T Ferguson, Julie C Yates, Lisa R Willits, and Jörgen Vestbo Respir Res. 2009; 10(1): 59. Published online 2009 June 30. doi: 10.1186/1465-9921-10-59.PMCID: PMC2714501 Mitogen-activated protein kinases and NFκB are involved in SP-A-enhanced responses of macrophages to mycobacteria Joseph P Lopez, David J Vigerust, and Virginia L Shepherd Respir Res. 2009; 10(1): 60. Published online 2009 July 1. doi: 10.1186/1465-9921-10-60.PMCID: PMC2717924 Arginine deficiency augments inflammatory mediator production by airway epithelial cells in vitro Xiao-Yun Fan, Arjen van den Berg, Mieke Snoek, Laurens G van der Flier, Barbara Smids, Henk M Jansen, Rong-Yu Liu, and René Lutter Respir Res. 2009; 10(1): 62. Published online 2009 July 3. doi: 10.1186/1465-9921-10-62.PMCID: PMC2714041 Macrorheology of cystic fibrosis, chronic obstructive pulmonary disease & normal sputum David J Serisier, Mary P Carroll, Janis K Shute, and Simon A Young Respir Res. 2009; 10(1): 63. Published online 2009 July 6. doi: 10.1186/1465-9921-10-63.PMCID: PMC2712464 Inflammatory parameters predict etiologic patterns but do not allow for individual prediction of etiology in patients with CAP – Results from the German competence network CAPNETZ Stefan Krüger, Santiago Ewig, Jana Papassotiriou, Jan Kunde, Reinhard Marre, Heike von Baum, Norbert Suttor, Tobias Welte, and the CAPNETZ study group Respir Res. 2009; 10(1): 65. Published online 2009 July 12. doi: 10.1186/1465-9921-10-65.PMCID: PMC2714042 Modulation of lung inflammation by vessel dilator in a mouse model of allergic asthma Xiaoqin Wang, Weidong Xu, Xiaoyuan Kong, Dongqing Chen, Gary Hellermann, Terry A Ahlert, Joseph D Giaimo, Stephania A Cormier, Xu Li, Richard F Lockey, Subhra Mohapatra, and Shyam S Mohapatra Respir Res. 2009; 10(1): 66. Published online 2009 July 17. doi: 10.1186/1465-9921-10-66.PMCID: PMC2716304 Importin-13 genetic variation is associated with improved airway responsiveness in childhood asthma Benjamin A Raby, Kristel Van Steen, Jessica Lasky-Su, Kelan Tantisira, Feige Kaplan, and Scott T Weiss Respir Res. 2009; 10(1): 67. Published online 2009 July 20. doi: 10.1186/1465-9921-10-67.PMCID: PMC2724419 Candida soluble cell wall β-glucan facilitates ovalbumin-induced allergic airway inflammation in mice: Possible role of antigen-presenting cells Ken-ichiro Inoue, Hirohisa Takano, Eiko Koike, Rie Yanagisawa, Toshio Oda, Hiroshi Tamura, Yoshiyuki Adachi, Ken-ichi Ishibashi, and Naohito Ohno Respir Res. 2009; 10(1): 68. Published online 2009 July 21. doi: 10.1186/1465-9921-10-68.PMCID: PMC2731726 Concomitant therapy with Cineole (Eucalyptole) reduces exacerbations in COPD: A placebo-controlled double-blind trial Heinrich Worth, Christian Schacher, and Uwe Dethlefsen Respir Res. 2009; 10(1): 69. Published online 2009 July 22. doi: 10.1186/1465-9921-10-69.PMCID: PMC2720945 Allergic lung inflammation alters neither susceptibility to Streptococcus pneumoniae infection nor inducibility of innate resistance in mice Cecilia G Clement, Michael J Tuvim, Christopher M Evans, Daniel M Tuvin, Burton F Dickey, and Scott E Evans Respir Res. 2009; 10(1): 70. Published online 2009 July 27. doi: 10.1186/1465-9921-10-70.PMCID: PMC2724420 Responses of FEV6, FVC, and FET to inhaled bronchodilator in the adult general population Annette Kainu, Ari Lindqvist, Seppo Sarna, Bo Lundbäck, and Anssi Sovijärvi Respir Res. 2009; 10(1): 71. Published online 2009 July 28. doi: 10.1186/1465-9921-10-71.PMCID: PMC2729739 MMP/TIMP expression profiles in distinct lung disease models: implications for possible future therapies Sissie Wong, Maria G Belvisi, and Mark A Birrell Respir Res. 2009; 10(1): 72. Published online 2009 August 3. doi: 10.1186/1465-9921-10-72.PMCID: PMC2728516 Level and course of FEV1 in relation to polymorphisms in NFE2L2 and KEAP1 in the general population Mateusz Siedlinski, Dirkje S Postma, Jolanda MA Boer, Gerrit van der Steege, Jan P Schouten, Henriette A Smit, and H Marike Boezen Respir Res. 2009; 10(1): 73. Published online 2009 August 11. doi: 10.1186/1465-9921-10-73.PMCID: PMC2738671 Corticomotor control of the genioglossus in awake OSAS patients: a transcranial magnetic stimulation study Frédéric Sériès, Wei Wang, and Thomas Similowski Respir Res. 2009; 10(1): 74. Published online 2009 August 13. doi: 10.1186/1465-9921-10-74.PMCID: PMC2738672 Exploring the optimum approach to the use of CT densitometry in a randomised placebo-controlled study of augmentation therapy in alpha 1-antitrypsin deficiency David G Parr, Asger Dirksen, Eeva Piitulainen, Chunqin Deng, Marion Wencker, and Robert A Stockley Respir Res. 2009; 10(1): 75. Published online 2009 August 13. doi: 10.1186/1465-9921-10-75.PMCID: PMC2740846 The angiogenic factor midkine is regulated by dexamethasone and retinoic acid during alveolarization and in alveolar epithelial cells Huayan Zhang, Samuel J Garber, Zheng Cui, Joseph P Foley, Gopi S Mohan, Minesh Jobanputra, Feige Kaplan, Neil B Sweezey, Linda W Gonzales, and Rashmin C Savani Respir Res. 2009; 10(1): 77. Published online 2009 August 21. doi: 10.1186/1465-9921-10-77.PMCID: PMC2739515 Comparison of exhaled breath condensate pH using two commercially available devices in healthy controls, asthma and COPD patients Rembert Koczulla, Silvano Dragonieri, Robert Schot, Robert Bals, Stefanie A Gauw, Claus Vogelmeier, Klaus F Rabe, Peter J Sterk, and Pieter S Hiemstra Respir Res. 2009; 10(1): 78. Published online 2009 August 24. doi: 10.1186/1465-9921-10-78.PMCID: PMC2747836 Effects of intratracheal administration of nuclear factor-kappaB decoy oligodeoxynucleotides on long-term cigarette smoke-induced lung inflammation and pathology in mice Yu-Tao Li, Bei He, Yu-Zhu Wang, and Jing Wang Respir Res. 2009; 10(1): 79. Published online 2009 August 25. doi: 10.1186/1465-9921-10-79.PMCID: PMC2751757 Macrophage derived chemokine (CCL22), thymus and activation-regulated chemokine (CCL17), and CCR4 in idiopathic pulmonary fibrosis Yurika Yogo, Seitaro Fujishima, Takashi Inoue, Fumitake Saito, Takayuki Shiomi, Kazuhiro Yamaguchi, and Akitoshi Ishizaka Respir Res. 2009; 10(1): 80. Published online 2009 August 29. doi: 10.1186/1465-9921-10-80.PMCID: PMC2741459 Expression profiling identifies genes involved in emphysema severity Santiyagu M Savarimuthu Francis, Jill E Larsen, Sandra J Pavey, Rayleen V Bowman, Nicholas K Hayward, Kwun M Fong, and Ian A Yang Respir Res. 2009; 10(1): 81. Published online 2009 September 2. doi: 10.1186/1465-9921-10-81.PMCID: PMC2746189 The mode of lymphoblastoid cell death in response to gas phase cigarette smoke is dose-dependent Nadia D Sdralia, Alexandra L Patmanidi, Athanassios D Velentzas, Loukas H Margaritis, George E Baltatzis, Dimitris G Hatzinikolaou, and Anastasia Stavridou Respir Res. 2009; 10(1): 82. Published online 2009 September 10. doi: 10.1186/1465-9921-10-82.PMCID: PMC2753584 Inflammatory cytokines, goblet cell hyperplasia and altered lung mechanics in Lgl1+/- mice Jie Lan, Leslie Ribeiro, Isabel Mandeville, Katia Nadeau, Tim Bao, Salomon Cornejo, Neil B Sweezey, and Feige Kaplan Respir Res. 2009; 10(1): 83. Published online 2009 September 21. doi: 10.1186/1465-9921-10-83.PMCID: PMC2760518 Intratracheal synthetic CpG oligodeoxynucleotide causes acute lung injury with systemic inflammatory response Sadatomo Tasaka, Hirofumi Kamata, Keisuke Miyamoto, Yasushi Nakano, Hiromi Shinoda, Yoshifumi Kimizuka, Hiroshi Fujiwara, Naoki Hasegawa, Seitaro Fujishima, Taku Miyasho, and Akitoshi Ishizaka Respir Res. 2009; 10(1): 84. Published online 2009 September 23. doi: 10.1186/1465-9921-10-84.PMCID: PMC2761862 Systemic T-helper and T-regulatory cell type cytokine responses in rhinovirus vs. respiratory syncytial virus induced early wheezing: an observational study Tuomas Jartti, Maria Paul-Anttila, Pasi Lehtinen, Vilhelmiina Parikka, Tytti Vuorinen, Olli Simell, and Olli Ruuskanen Respir Res. 2009; 10(1): 85. Published online 2009 September 25. doi: 10.1186/1465-9921-10-85.PMCID: PMC2762974 Gene promoter methylation assayed in exhaled breath, with differences in smokers and lung cancer patients Weiguo Han, Tao Wang, Andrew A Reilly, Steven M Keller, and Simon D Spivack Respir Res. 2009; 10(1): 86. Published online 2009 September 25. doi: 10.1186/1465-9921-10-86.PMCID: PMC2759916 Truncating and missense BMPR2 mutations differentially affect the severity of heritable pulmonary arterial hypertension Eric D Austin, John A Phillips, Joy D Cogan, Rizwan Hamid, Chang Yu, Krista C Stanton, Charles A Phillips, Lisa A Wheeler, Ivan M Robbins, John H Newman, and James E Loyd Respir Res. 2009; 10(1): 87. Published online 2009 September 28. doi: 10.1186/1465-9921-10-87.PMCID: PMC2762975 PKA and Epac cooperate to augment bradykinin-induced interleukin-8 release from human airway smooth muscle cells Sara S Roscioni, Loes EM Kistemaker, Mark H Menzen, Carolina RS Elzinga, Reinoud Gosens, Andrew J Halayko, Herman Meurs, and Martina Schmidt Respir Res. 2009; 10(1): 88. Published online 2009 September 29. doi: 10.1186/1465-9921-10-88.PMCID: PMC2764632 Anti-inflammatory effects of antibacterials on human bronchial epithelial cells Gregor S Zimmermann, Claus Neurohr, Heidrun Villena-Hermoza, Rudolf Hatz, and Juergen Behr Respir Res. 2009; 10(1): 89. Published online 2009 September 29. doi: 10.1186/1465-9921-10-89.PMCID: PMC2764633 The effect of titanium dioxide nanoparticles on pulmonary surfactant function and ultrastructure Carsten Schleh, Christian Mühlfeld, Karin Pulskamp, Andreas Schmiedl, Matthias Nassimi, Hans D Lauenstein, Armin Braun, Norbert Krug, Veit J Erpenbeck, and Jens M Hohlfeld Respir Res. 2009; 10(1): 90. Published online 2009 September 30. doi: 10.1186/1465-9921-10-90.PMCID: PMC2765946 Ethyl pyruvate reduces mortality in an endotoxin-induced severe acute lung injury mouse model Guan-Hong Shang, Dian-Jie Lin, Wei Xiao, Chong-Qi Jia, Yu Li, Ai-Hua Wang, and Liang Dong Respir Res. 2009; 10(1): 91. Published online 2009 October 2. doi: 10.1186/1465-9921-10-91.PMCID: PMC2768703 Global gene expression patterns in the post-pneumonectomy lung of adult mice Julia A Paxson, Christopher D Parkin, Lakshmanan K Iyer, Melissa R Mazan, Edward P Ingenito, and Andrew M Hoffman Respir Res. 2009; 10(1): 92. Published online 2009 October 5. doi: 10.1186/1465-9921-10-92.PMCID: PMC2770038 GITR signaling potentiates airway hyperresponsiveness by enhancing Th2 cell activity in a mouse model of asthma Alexandre C Motta, Joost LM Vissers, Renée Gras, Betty CAM Van Esch, Antoon JM Van Oosterhout, and Martijn C Nawijn Respir Res. 2009; 10(1): 93. Published online 2009 October 7. doi: 10.1186/1465-9921-10-93.PMCID: PMC2767348 West Sweden Asthma Study: Prevalence trends over the last 18 years argues no recent increase in asthma Jan Lötvall, Linda Ekerljung, Erik P Rönmark, Göran Wennergren, Anders Lindén, Eva Rönmark, Kjell Torén, and Bo Lundbäck Respir Res. 2009; 10(1): 94. Published online 2009 October 12. doi: 10.1186/1465-9921-10-94.PMCID: PMC2772988 Differential effects of cytokines and corticosteroids on Toll-like receptor 2 expression and activity in human airway epithelia Audra A Winder, Christine Wohlford-Lenane, Todd E Scheetz, Brie N Nardy, Lori J Manzel, Dwight C Look, and Paul B McCray, Jr Respir Res. 2009; 10(1): 96. Published online 2009 October 16. doi: 10.1186/1465-9921-10-96.PMCID: PMC2772856 Expression of endothelia and lymphocyte adhesion molecules in bronchus-associated lymphoid tissue (BALT) in adult human lung Nakaaki Kawamata, Baohui Xu, Hiroo Nishijima, Kohji Aoyama, Mayumi Kusumoto, Toru Takeuchi, Chuwa Tei, Sara A Michie, and Takami Matsuyama Respir Res. 2009; 10(1): 97. Published online 2009 October 22. doi: 10.1186/1465-9921-10-97.PMCID: PMC2772857 Asthma and genes encoding components of the vitamin D pathway Yohan Bossé, Mathieu Lemire, Audrey H Poon, Denise Daley, Jian-Qing He, Andrew Sandford, John H White, Alan L James, Arthur William Musk, Lyle J Palmer, Benjamin A Raby, Scott T Weiss, Anita L Kozyrskyj, Allan Becker, Thomas J Hudson, and Catherine Laprise Respir Res. 2009; 10(1): 98. Published online 2009 October 24. doi: 10.1186/1465-9921-10-98.PMCID: PMC2779188 Successful establishment of primary small airway cell cultures in human lung transplantation Balarka Banerjee, Anthony Kicic, Michael Musk, Erika N Sutanto, Stephen M Stick, and Daniel C Chambers Respir Res. 2009; 10(1): 99. Published online 2009 October 26. doi: 10.1186/1465-9921-10-99.PMCID: PMC2774672 TGF-β1 induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells is enhanced by IL-1β but not abrogated by corticosteroids Astrid M Doerner and Bruce L Zuraw Respir Res. 2009; 10(1): 100. Published online 2009 October 27. doi: 10.1186/1465-9921-10-100.PMCID: PMC2774671 Lung function in idiopathic pulmonary fibrosis - extended analyses of the IFIGENIA trial Jürgen Behr, Maurits Demedts, Roland Buhl, Ulrich Costabel, Richard PN Dekhuijzen, Henk M Jansen, William MacNee, Michiel Thomeer, Benoit Wallaert, Francois Laurent, Andrew G Nicholson, Eric K Verbeken, Johny Verschakelen, CDR Flower, Stefano Petruzzelli, Paul De Vuyst, JMM van den Bosch, Eulogio Rodriguez-Becerra, Ida Lankhorst, Marco Sardina, Gabrielle Boissard, and the Ifigenia study group* Respir Res. 2009; 10(1): 101. Published online 2009 October 27. doi: 10.1186/1465-9921-10-101.PMCID: PMC2774307 Influenza H5N1 virus infection of polarized human alveolar epithelial cells and lung microvascular endothelial cells Michael CW Chan, Renee WY Chan, Wendy CL Yu, Carol CC Ho, WH Chui, CK Lo, Kit M Yuen, Yi Guan, John M Nicholls, and JS Malik Peiris Respir Res. 2009; 10(1): 102. Published online 2009 October 30. doi: 10.1186/1465-9921-10-102.PMCID: PMC2780994 Fibrocytes are associated with vascular and parenchymal remodelling in patients with obliterative bronchiolitis Annika Andersson-Sjöland, Jonas S Erjefält, Leif Bjermer, Leif Eriksson, and Gunilla Westergren-Thorsson Respir Res. 2009; 10(1): 103. Published online 2009 October 30. doi: 10.1186/1465-9921-10-103.PMCID: PMC2774308 The bioavailability and airway clearance of the steroid component of budesonide/formoterol and salmeterol/fluticasone after inhaled administration in patients with COPD and healthy subjects: a randomized controlled trial Chris Dalby, Tomasz Polanowski, Thomas Larsson, Lars Borgström, Staffan Edsbäcker, and Tim W Harrison Respir Res. 2009; 10(1): 104. Published online 2009 October 31. doi: 10.1186/1465-9921-10-104.PMCID: PMC2780403 Generation of lung epithelial-like tissue from human embryonic stem cells Lindsey Van Haute, Gert De Block, Inge Liebaers, Karen Sermon, and Martine De Rycke Respir Res. 2009; 10(1): 105. Published online 2009 November 5. doi: 10.1186/1465-9921-10-105.PMCID: PMC2777141 Long-term gas exchange characteristics as markers of deterioration in patients with cystic fibrosis Richard Kraemer, Philipp Latzin, Isabelle Pramana, Pietro Ballinari, Sabina Gallati, and Urs Frey Respir Res. 2009; 10(1): 106. Published online 2009 November 12. doi: 10.1186/1465-9921-10-106.PMCID: PMC2780404 Increased levels of (class switched) memory B cells in peripheral blood of current smokers Corry-Anke Brandsma, Machteld N Hylkema, Marie Geerlings, Wouter H van Geffen, Dirkje S Postma, Wim Timens, and Huib AM Kerstjens Respir Res. 2009; 10(1): 108. Published online 2009 November 12. doi: 10.1186/1465-9921-10-108.PMCID: PMC2779187 Nitric oxide synthases in infants and children with pulmonary hypertension and congenital heart disease Thomas Hoehn, Brigitte Stiller, Allan R McPhaden, and Roger M Wadsworth Respir Res. 2009; 10(1): 110. Published online 2009 November 13. doi: 10.1186/1465-9921-10-110.PMCID: PMC2780406 Correction 'Diagnosing Asthma in General Practice with Portable Exhaled Nitric Oxide Measurement – Results of a Prospective Diagnostic Study: FENO ≤ 16 ppb better than FENO ≤ 12 ppb to rule out mild and moderate to severe asthma Antonius Schneider, Lisa Tilemann, Tjard Schermer, Lena Gindner, Gunter Laux, Joachim Szecsenyi, and Franz Joachim Meyer Respir Res. 2009; 10(1): 64. Published online 2009 July 7. doi: 10.1186/1465-9921-10-64.PMCID: PMC2713211 Corrects: Antonius Schneider, et al. Diagnosing asthma in general practice with portable exhaled nitric oxide measurement – results of a prospective diagnostic study. Respir Res. 2009; 10(1): 15.
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