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Volume 13(6);  2011

Viewpoints

Cancer's sweet tooth for serine
Ji Luo
Breast Cancer Res. 2011; 13(6): 317. Published online 2011 November 28. doi: 10.1186/bcr2932
PMCID:
PMC3315682
Abstract Full Text PDF–175K
New insights into the role of androgen and oestrogen receptors in molecular apocrine breast tumours
Richard D Iggo
Breast Cancer Res. 2011; 13(6): 318. Published online 2011 December 8. doi: 10.1186/bcr3036
PMCID:
PMC3326548
Free in PMC on 2012/06/08

Research Articles

Protein expression, survival and docetaxel benefit in node-positive breast cancer treated with adjuvant chemotherapy in the FNCLCC - PACS 01 randomized trial
Jocelyne Jacquemier, Jean-Marie Boher, Henri Roche, Benjamin Esterni, Daniel Serin, Pierre Kerbrat, Fabrice Andre, Pascal Finetti, Emmanuelle Charafe-Jauffret, Anne-Laure Martin, Mario Campone, Patrice Viens, Daniel Birnbaum, Frédérique Penault-Llorca, François Bertucci
Breast Cancer Res. 2011; 13(6): R109. Published online 2011 November 1. doi: 10.1186/bcr3051
PMCID:
PMC3326551
Abstract Full Text PDF–438K Supplementary Material
Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2
Anna Marie Mulligan, Fergus J Couch, Daniel Barrowdale, Susan M Domchek, Diana Eccles, Heli Nevanlinna, Susan J Ramus, Mark Robson, Mark Sherman, Amanda B Spurdle, Barbara Wappenschmidt, Andrew Lee, Lesley McGuffog, Sue Healey, Olga M Sinilnikova, Ramunas Janavicius, Thomas vO Hansen, Finn C Nielsen, Bent Ejlertsen, Ana Osorio, Iván Muñoz-Repeto, Mercedes Durán, Javier Godino, Maroulio Pertesi, Javier Benítez, Paolo Peterlongo, Siranoush Manoukian, Bernard Peissel, Daniela Zaffaroni, Elisa Cattaneo, Bernardo Bonanni, Alessandra Viel, Barbara Pasini, Laura Papi, Laura Ottini, Antonella Savarese, Loris Bernard, Paolo Radice, Ute Hamann, Martijn Verheus, Hanne EJ Meijers-Heijboer, Juul Wijnen, Encarna B Gómez García, Marcel R Nelen, C Marleen Kets, Caroline Seynaeve, Madeleine MA Tilanus-Linthorst, Rob B van der Luijt, Theo van Os, Matti Rookus, Debra Frost, J Louise Jones, D Gareth Evans, Fiona Lalloo, Ros Eeles, Louise Izatt, Julian Adlard, Rosemarie Davidson, Jackie Cook, Alan Donaldson, Huw Dorkins, Helen Gregory, Jacqueline Eason, Catherine Houghton, Julian Barwell, Lucy E Side, Emma McCann, Alex Murray, Susan Peock, Andrew K Godwin, Rita K Schmutzler, Kerstin Rhiem, Christoph Engel, Alfons Meindl, Ina Ruehl, Norbert Arnold, Dieter Niederacher, Christian Sutter, Helmut Deissler, Dorothea Gadzicki, Karin Kast, Sabine Preisler-Adams, Raymonda Varon-Mateeva, Ines Schoenbuchner, Britta Fiebig, Wolfram Heinritz, Dieter Schäfer, Heidrun Gevensleben, Virginie Caux-Moncoutier, Marion Fassy-Colcombet, François Cornelis, Sylvie Mazoyer, Mélanie Léoné, Nadia Boutry-Kryza, Agnès Hardouin, Pascaline Berthet, Danièle Muller, Jean-Pierre Fricker, Isabelle Mortemousque, Pascal Pujol, Isabelle Coupier, Marine Lebrun, Caroline Kientz, Michel Longy, Nicolas Sevenet, Dominique Stoppa-Lyonnet, Claudine Isaacs, Trinidad Caldes, Miguel de la Hoya, Tuomas Heikkinen, Kristiina Aittomäki, Ignacio Blanco, Conxi Lazaro, Rosa B Barkardottir, Penny Soucy, Martine Dumont, Jacques Simard, Marco Montagna, Silvia Tognazzo, Emma D'Andrea, Stephen Fox, Max Yan, Tim Rebbeck, Olufunmilayo I Olopade, Jeffrey N Weitzel, Henry T Lynch, Patricia A Ganz, Gail E Tomlinson, Xianshu Wang, Zachary Fredericksen, Vernon S Pankratz, Noralane M Lindor, Csilla Szabo, Kenneth Offit, Rita Sakr, Mia Gaudet, Jasmine Bhatia, Noah Kauff, Christian F Singer, Muy-Kheng Tea, Daphne Gschwantler-Kaulich, Anneliese Fink-Retter, Phuong L Mai, Mark H Greene, Evgeny Imyanitov, Frances P O'Malley, Hilmi Ozcelik, Gordon Glendon, Amanda E Toland, Anne-Marie Gerdes, Mads Thomassen, Torben A Kruse, Uffe Birk Jensen, Anne-Bine Skytte, Maria A Caligo, Maria Soller, Karin Henriksson, von Anna Wachenfeldt, Brita Arver, Marie Stenmark-Askmalm, Per Karlsson, Yuan Chun Ding, Susan L Neuhausen, Mary Beattie, Paul DP Pharoah, Kirsten B Moysich, Katherine L Nathanson, Beth Y Karlan, Jenny Gross, Esther M John, Mary B Daly, Saundra M Buys, Melissa C Southey, John L Hopper, Mary Beth Terry, Wendy Chung, Alexander F Miron, David Goldgar, Georgia Chenevix-Trench, Douglas F Easton, Irene L Andrulis, Antonis C Antoniou
Breast Cancer Res. 2011; 13(6): R110. Published online 2011 November 2. doi: 10.1186/bcr3052
PMCID:
PMC3326552
Abstract Full Text PDF–471K Supplementary Material
Loss of interferon regulatory factor 5 (IRF5) expression in human ductal carcinoma correlates with disease stage and contributes to metastasis
Xiaohui Bi, Meera Hameed, Neena Mirani, Erica Maria Pimenta, Jason Anari, Betsy J Barnes
Breast Cancer Res. 2011; 13(6): R111. Published online 2011 November 4. doi: 10.1186/bcr3053
PMCID:
PMC3326553
Abstract Full Text PDF–1.3M Supplementary Material
ARTEMIN synergizes with TWIST1 to promote metastasis and poor survival outcome in patients with ER negative mammary carcinoma
Arindam Banerjee, Zheng-Sheng Wu, PengXu Qian, Jian Kang, Vijay Pandey, Dong-Xu Liu, Tao Zhu, Peter E Lobie
Breast Cancer Res. 2011; 13(6): R112. Published online 2011 November 7. doi: 10.1186/bcr3054
PMCID:
PMC3326554
Abstract Full Text PDF–1.1M Supplementary Material
Sensitization of epithelial growth factor receptors by nicotine exposure to promote breast cancer cell growth
Takashi Nishioka, Hyun-Seok Kim, Ling-Yu Luo, Yi Huang, Jinjin Guo, Chang Yan Chen
Breast Cancer Res. 2011; 13(6): R113. Published online 2011 November 15. doi: 10.1186/bcr3055
PMCID:
PMC3326555
Abstract Full Text PDF–531K
Single nucleotide polymorphisms associated with risk for contralateral breast cancer in the Women's Environment, Cancer, and Radiation Epidemiology (WECARE) Study
Sharon N Teraoka, Jonine L Bernstein, Anne S Reiner, Robert W Haile, Leslie Bernstein, Charles F Lynch, Kathleen E Malone, Marilyn Stovall, Marinela Capanu, Xiaolin Liang, Susan A Smith, Josyf Mychaleckyj, Xuanlin Hou, Lene Mellemkjaer, John D Boice, Jr, Ashley Siniard, David Duggan, Duncan C Thomas
Breast Cancer Res. 2011; 13(6): R114. Published online 2011 November 17. doi: 10.1186/bcr3057
PMCID:
PMC3326556
Abstract Full Text PDF–282K Supplementary Material
Inhibition of cathepsin B activity attenuates extracellular matrix degradation and inflammatory breast cancer invasion
Bernadette C Victor, Arulselvi Anbalagan, Mona M Mohamed, Bonnie F Sloane, Dora Cavallo-Medved
Breast Cancer Res. 2011; 13(6): R115. Published online 2011 November 17. doi: 10.1186/bcr3058
PMCID:
PMC3326557
Abstract Full Text PDF–1.9M Supplementary Material
miRNA-34b as a tumor suppressor in estrogen-dependent growth of breast cancer cells
Yee-Ming Lee, Jen-Yi Lee, Chao-Chi Ho, Qi-Sheng Hong, Sung-Liang Yu, Chii-Ruey Tzeng, Pan-Chyr Yang, Huei-Wen Chen
Breast Cancer Res. 2011; 13(6): R116. Published online 2011 November 23. doi: 10.1186/bcr3059
PMCID:
PMC3326558
Abstract Full Text PDF–4.9M Supplementary Material
A different immunologic profile characterizes patients with HER-2-overexpressing and HER-2-negative locally advanced breast cancer: implications for immune-based therapies
Elena Muraro, Debora Martorelli, Elisa Turchet, Gianmaria Miolo, Simona Scalone, Elisa Comaro, Renato Talamini, Katy Mastorci, Davide Lombardi, Tiziana Perin, Antonino Carbone, Andrea Veronesi, Diana Crivellari, Riccardo Dolcetti
Breast Cancer Res. 2011; 13(6): R117. Published online 2011 November 23. doi: 10.1186/bcr3060
PMCID:
PMC3326559
Abstract Full Text PDF–2.8M
Cancer stem cell markers in breast cancer: pathological, clinical and prognostic significance
H Raza Ali, Sarah-Jane Dawson, Fiona M Blows, Elena Provenzano, Paul D Pharoah, Carlos Caldas
Breast Cancer Res. 2011; 13(6): R118. Published online 2011 November 23. doi: 10.1186/bcr3061
PMCID:
PMC3326560
Abstract Full Text PDF–2.0M Supplementary Material
CHEK2 contribution to hereditary breast cancer in non-BRCA families
Alexis Desrichard, Yannick Bidet, Nancy Uhrhammer, Yves-Jean Bignon
Breast Cancer Res. 2011; 13(6): R119. Published online 2011 November 24. doi: 10.1186/bcr3062
PMCID:
PMC3326561
Abstract Full Text PDF–680K Supplementary Material
Targeting cholesterol-rich microdomains to circumvent tamoxifen-resistant breast cancer
Richa Tiwary, Weiping Yu, Linda A deGraffenried, Bob G Sanders, Kimberly Kline
Breast Cancer Res. 2011; 13(6): R120. Published online 2011 November 24. doi: 10.1186/bcr3063
PMCID:
PMC3326562
Abstract Full Text PDF–3.0M
Different mechanisms for resistance to trastuzumab versus lapatinib in HER2- positive breast cancers -- role of estrogen receptor and HER2 reactivation
Yen-Chao Wang, Gladys Morrison, Ryan Gillihan, Jun Guo, Robin M Ward, Xiaoyong Fu, Maria F Botero, Nuala A Healy, Susan G Hilsenbeck, Gail Lewis Phillips, Gary C Chamness, Mothaffar F Rimawi, C Kent Osborne, Rachel Schiff
Breast Cancer Res. 2011; 13(6): R121. Published online 2011 November 28. doi: 10.1186/bcr3067
PMCID:
PMC3326563
Abstract Full Text PDF–2.5M Supplementary Material
Advantages of adjuvant chemotherapy for patients with triple-negative breast cancer at Stage II: usefulness of prognostic markers E-cadherin and Ki67
Shinichiro Kashiwagi, Masakazu Yashiro, Tsutomu Takashima, Naoki Aomatsu, Katsumi Ikeda, Yoshinari Ogawa, Tetsuro Ishikawa, Kosei Hirakawa
Breast Cancer Res. 2011; 13(6): R122. Published online 2011 November 30. doi: 10.1186/bcr3068
PMCID:
PMC3326564
Abstract Full Text PDF–611K Supplementary Material
Anti-tumor activity and toxicokinetics analysis of MGAH22, an anti-HER2 monoclonal antibody with enhanced Fcγ receptor binding properties
Jeffrey L Nordstrom, Sergey Gorlatov, Wenjun Zhang, Yinhua Yang, Ling Huang, Steve Burke, Hua Li, Valentina Ciccarone, Tengfei Zhang, Jeffrey Stavenhagen, Scott Koenig, Stanford J Stewart, Paul A Moore, Syd Johnson, Ezio Bonvini
Breast Cancer Res. 2011; 13(6): R123. Published online 2011 November 30. doi: 10.1186/bcr3069
PMCID:
PMC3326565
Abstract Full Text PDF–618K
Activator protein 1 (AP-1) contributes to EpCAM-dependent breast cancer invasion
Narendra V Sankpal, John D Mayfield, Mike W Willman, Timothy P Fleming, William E Gillanders
Breast Cancer Res. 2011; 13(6): R124. Published online 2011 December 1. doi: 10.1186/bcr3070
PMCID:
PMC3326566
Abstract Full Text PDF–1.3M
Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases
Barbara Adamo, Allison M Deal, Emily Burrows, Joseph Geradts, Erika Hamilton, Kimberly L Blackwell, Chad Livasy, Karen Fritchie, Aleix Prat, J Chuck Harrell, Matthew G Ewend, Lisa A Carey, C Ryan Miller, Carey K Anders
Breast Cancer Res. 2011; 13(6): R125. Published online 2011 December 1. doi: 10.1186/bcr3071
PMCID:
PMC3326567
Abstract Full Text PDF–1.9M
Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer
Nathan R West, Katy Milne, Pauline T Truong, Nicol Macpherson, Brad H Nelson, Peter H Watson
Breast Cancer Res. 2011; 13(6): R126. Published online 2011 December 8. doi: 10.1186/bcr3072
PMCID:
PMC3326568
Abstract Full Text PDF–2.2M Supplementary Material
Regulation of breast cancer metastasis by Runx2 and estrogen signaling: the role of SNAI2
Nyam-Osor Chimge, Sanjeev K Baniwal, Gillian H Little, Yi-bu Chen, Michael Kahn, Debu Tripathy, Zea Borok, Baruch Frenkel
Breast Cancer Res. 2011; 13(6): R127. Published online 2011 December 9. doi: 10.1186/bcr3073
PMCID:
PMC3326569
Abstract Full Text PDF–836K Supplementary Material
Opposing roles of CXCR4 and CXCR7 in breast cancer metastasis
Lorena Hernandez, Marco AO Magalhaes, Salvatore J Coniglio, John S Condeelis, Jeffrey E Segall
Breast Cancer Res. 2011; 13(6): R128. Published online 2011 December 9. doi: 10.1186/bcr3074
PMCID:
PMC3326570
Abstract Full Text PDF–1009K Supplementary Material
Landscape of somatic allelic imbalances and copy number alterations in HER2-amplified breast cancer
Johan Staaf, Göran Jönsson, Markus Ringnér, Bo Baldetorp, Åke Borg
Breast Cancer Res. 2011; 13(6): R129. Published online 2011 December 14. doi: 10.1186/bcr3075
PMCID:
PMC3326571
Abstract Full Text PDF–845K Supplementary Material
Variants on the promoter region of PTEN affect breast cancer progression and patient survival
Tuomas Heikkinen, Dario Greco, Liisa M Pelttari, Johanna Tommiska, Pia Vahteristo, Päivi Heikkilä, Carl Blomqvist, Kristiina Aittomäki, Heli Nevanlinna
Breast Cancer Res. 2011; 13(6): R130. Published online 2011 December 15. doi: 10.1186/bcr3076
PMCID:
PMC3326572
Abstract Full Text PDF–628K Supplementary Material
A novel inhibitor of fatty acid synthase shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines
Teresa Puig, Helena Aguilar, Sílvia Cufí, Glòria Oliveras, Carlos Turrado, Sílvia Ortega-Gutiérrez, Bellinda Benhamú, María Luz López-Rodríguez, Ander Urruticoechea, Ramon Colomer
Breast Cancer Res. 2011; 13(6): R131. Published online 2011 December 16. doi: 10.1186/bcr3077
PMCID:
PMC3326573
Abstract Full Text PDF–4.5M Supplementary Material
A genome-wide linkage study of mammographic density, a risk factor for breast cancer
Celia MT Greenwood, Andrew D Paterson, Linda Linton, Irene L Andrulis, Carmel Apicella, Apostolos Dimitromanolakis, Valentina Kriukov, Lisa J Martin, Ayesha Salleh, Elena Samiltchuk, Rashmi V Parekh, Melissa C Southey, Esther M John, John L Hopper, Norman F Boyd, Johanna M Rommens
Breast Cancer Res. 2011; 13(6): R132. Published online 2011 December 21. doi: 10.1186/bcr3078
PMCID:
PMC3326574
Abstract Full Text PDF–2.2M Supplementary Material
Lack of EGFR-activating mutations in European patients with triple-negative breast cancer could emphasise geographic and ethnic variations in breast cancer mutation profiles
William Jacot, Evelyne Lopez-Crapez, Simon Thezenas, Romain Senal, Frédéric Fina, Frédéric Bibeau, Gilles Romieu, Pierre-Jean Lamy
Breast Cancer Res. 2011; 13(6): R133. Published online 2011 December 22. doi: 10.1186/bcr3079
PMCID:
PMC3326575
Abstract Full Text PDF–306K
Long-term prognosis of breast cancer detected by mammography screening or other methods
Tiina Lehtimäki, Mikael Lundin, Nina Linder, Harri Sihto, Kaija Holli, Taina Turpeenniemi-Hujanen, Vesa Kataja, Jorma Isola, Heikki Joensuu, Johan Lundin
Breast Cancer Res. 2011; 13(6): R134. Published online 2011 December 28. doi: 10.1186/bcr3080
PMCID:
PMC3326576
Abstract Full Text PDF–337K Supplementary Material

Reviews

Luminal-B breast cancer and novel therapeutic targets
Ben Tran, Philippe L Bedard
Breast Cancer Res. 2011; 13(6): 221. Published online 2011 November 30. doi: 10.1186/bcr2904
PMCID:
PMC3326541
Free in PMC on 2012/05/30
Mammographic density and breast cancer risk: current understanding and future prospects
Norman F Boyd, Lisa J Martin, Martin J Yaffe, Salomon Minkin
Breast Cancer Res. 2011; 13(6): 223. Published online 2011 November 1. doi: 10.1186/bcr2942
PMCID:
PMC3326547
Abstract Full Text PDF–560K
Mutations in the phosphatidylinositol 3-kinase pathway: role in tumor progression and therapeutic implications in breast cancer
Todd W Miller, Brent N Rexer, Joan T Garrett, Carlos L Arteaga
Breast Cancer Res. 2011; 13(6): 224. Published online 2011 November 1. doi: 10.1186/bcr3039
PMCID:
PMC3315683
Abstract Full Text PDF–766K
Epigenetics in breast cancer: what's new?
Yi Huang, Shweta Nayak, Rachel Jankowitz, Nancy E Davidson, Steffi Oesterreich
Breast Cancer Res. 2011; 13(6): 225. Published online 2011 November 1. doi: 10.1186/bcr2925
PMCID:
PMC3326545
Abstract Full Text PDF–309K
Breast cancer epithelial-to-mesenchymal transition: examining the functional consequences of plasticity
David J Drasin, Tyler P Robin, Heide L Ford
Breast Cancer Res. 2011; 13(6): 226. Published online 2011 November 1. doi: 10.1186/bcr3037
PMCID:
PMC3326549
Abstract Full Text PDF–274K
The microenvironment in breast cancer progression: biology and implications for treatment
Andrew E Place, Sung Jin Huh, Kornelia Polyak
Breast Cancer Res. 2011; 13(6): 227. Published online 2011 November 1. doi: 10.1186/bcr2912
PMCID:
PMC3326543
Abstract Full Text PDF–1.5M
Clinical relevance and biology of circulating tumor cells
Natalia Bednarz-Knoll, Catherine Alix-Panabières, Klaus Pantel
Breast Cancer Res. 2011; 13(6): 228. Published online 2011 November 1. doi: 10.1186/bcr2940
PMCID:
PMC3326546
Abstract Full Text PDF–257K
β1-integrins signaling and mammary tumor progression in transgenic mouse models: implications for human breast cancer
Hicham Lahlou, William J Muller
Breast Cancer Res. 2011; 13(6): 229. Published online 2011 November 30. doi: 10.1186/bcr2905
PMCID:
PMC3326542
Free in PMC on 2012/05/30
'Omic approaches to preventing or managing metastatic breast cancer
Obi L Griffith, Joe W Gray
Breast Cancer Res. 2011; 13(6): 230. Published online 2011 December 8. doi: 10.1186/bcr2923
PMCID:
PMC3326544
Free in PMC on 2012/06/08

Editorial

Breast cancer: current state and future promise
Lewis A Chodosh
Breast Cancer Res. 2011; 13(6): 113. Published online 2011 November 1. doi: 10.1186/bcr3045
PMCID:
PMC3326550
Full Text PDF–122K
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