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Volume 37(20);  November 2009
Front-Matter/Back-Matter
Nucleic Acids Research: VOLUME 37 ISSUE 20 2009
Nucleic Acids Res. 2009 November; 37(20): i. Published online 2009 November. doi: 10.1093/nar/gkp1111.
PMCID: PMC2777441
Nucleic Acids Research
Nucleic Acids Res. 2009 November; 37(20): ii. Published online 2009 November. doi: 10.1093/nar/gkp1110.
PMCID: PMC2777449
Subscriptions
Nucleic Acids Res. 2009 November; 37(20): iii. Published online 2009 November. doi: 10.1093/nar/gkp1112.
PMCID: PMC2777436
Gene Regulation, Chromatin and Epigenetics
Transcription from bacteriophage λ pR promoter is regulated independently and antagonistically by DksA and ppGpp
Robert Łyżeń, Maja Kochanowska, Grzegorz Węgrzyn, and Agnieszka Szalewska-Pałasz
Nucleic Acids Res. 2009 November; 37(20): 6655–6664. Published online 2009 November. doi: 10.1093/nar/gkp676.
PMCID: PMC2777414
The loss of histone H3 lysine 9 acetylation due to dSAGA-specific dAda2b mutation influences the expression of only a small subset of genes
Nóra Zsindely, Tibor Pankotai, Zsuzsanna Újfaludi, Dániel Lakatos, Orbán Komonyi, László Bodai, László Tora, and Imre M. Boros
Nucleic Acids Res. 2009 November; 37(20): 6665–6680. Published online 2009 November. doi: 10.1093/nar/gkp722.
PMCID: PMC2777428
MeCP2/H3meK9 are involved in IL-6 gene silencing in pancreatic adenocarcinoma cell lines
Mario Dandrea, Massimo Donadelli, Chiara Costanzo, Aldo Scarpa, and Marta Palmieri
Nucleic Acids Res. 2009 November; 37(20): 6681–6690. Published online 2009 November. doi: 10.1093/nar/gkp723.
PMCID: PMC2777443
GSK3β is a negative regulator of the transcriptional coactivator MAML1
Mariana Saint Just Ribeiro, Magnus L. Hansson, Mikael J. Lindberg, Anita E. Popko-Ścibor, and Annika E. Wallberg
Nucleic Acids Res. 2009 November; 37(20): 6691–6700. Published online 2009 November. doi: 10.1093/nar/gkp724.
PMCID: PMC2777432
In vivo methylation of mtDNA reveals the dynamics of protein–mtDNA interactions
Adriana P. Rebelo, Sion L. Williams, and Carlos T. Moraes
Nucleic Acids Res. 2009 November; 37(20): 6701–6715. Published online 2009 November. doi: 10.1093/nar/gkp727.
PMCID: PMC2777446
Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression
Himesh Fernando, Sven Sewitz, Jeremy Darot, Simon Tavaré, Julian Leon Huppert, and Shankar Balasubramanian
Nucleic Acids Res. 2009 November; 37(20): 6716–6722. Published online 2009 November. doi: 10.1093/nar/gkp740.
PMCID: PMC2777450
Regulation of transcription termination in the nematode Caenorhabditis elegans
Simon Haenni, Helen E. Sharpe, Maria Gravato Nobre, Kerstin Zechner, Cathy Browne, Jonathan Hodgkin, and André Furger
Nucleic Acids Res. 2009 November; 37(20): 6723–6736. Published online 2009 November. doi: 10.1093/nar/gkp744.
PMCID: PMC2777434
Genome Integrity, Repair and Replication
Translesion DNA synthesis-assisted non-homologous end-joining of complex double-strand breaks prevents loss of DNA sequences in mammalian cells
Shay Covo, Jean-Pierre de Villartay, Penny A. Jeggo, and Zvi Livneh
Nucleic Acids Res. 2009 November; 37(20): 6737–6745. Published online 2009 November. doi: 10.1093/nar/gkp703.
PMCID: PMC2777433
Involvement of p54(nrb), a PSF partner protein, in DNA double-strand break repair and radioresistance
Shuyi Li, Wendy W. Kuhne, Anita Kulharya, Farlyn Z. Hudson, Kyungsoo Ha, Zhen Cao, and William S. Dynan
Nucleic Acids Res. 2009 November; 37(20): 6746–6753. Published online 2009 November. doi: 10.1093/nar/gkp741.
PMCID: PMC2777424
Functional significance of the Rad51-Srs2 complex in Rad51 presynaptic filament disruption
Sierra Colavito, Margaret Macris-Kiss, Changhyun Seong, Olive Gleeson, Eric C. Greene, Hannah L. Klein, Lumir Krejci, and Patrick Sung
Nucleic Acids Res. 2009 November; 37(20): 6754–6764. Published online 2009 November. doi: 10.1093/nar/gkp748.
PMCID: PMC2777448
Biophysical characterizations of human mitochondrial transcription factor A and its binding to tumor suppressor p53
Tuck Seng Wong, Sridharan Rajagopalan, Stefan M. Freund, Trevor J. Rutherford, Antonina Andreeva, Fiona M. Townsley, Miriana Petrovich, and Alan R. Fersht
Nucleic Acids Res. 2009 November; 37(20): 6765–6783. Published online 2009 November. doi: 10.1093/nar/gkp750.
PMCID: PMC2777442
Molecular Biology
Predictable suppression of gene expression by 5′-UTR-based RNA quadruplexes
Kangkan Halder, Markus Wieland, and Jörg S. Hartig
Nucleic Acids Res. 2009 November; 37(20): 6811–6817. Published online 2009 November. doi: 10.1093/nar/gkp696.
PMCID: PMC2777418
Characterization of RNA aptamers that disrupt the RUNX1–CBFβ/DNA complex
Jenny L. Barton, David H. J. Bunka, Stuart E. Knowling, Pascal Lefevre, Alan J. Warren, Constanze Bonifer, and Peter G. Stockley
Nucleic Acids Res. 2009 November; 37(20): 6818–6830. Published online 2009 November. doi: 10.1093/nar/gkp728.
PMCID: PMC2777437
DNA translocation activity of the multifunctional replication protein ORF904 from the archaeal plasmid pRN1
Martin Sanchez, Markus Drechsler, Holger Stark, and Georg Lipps
Nucleic Acids Res. 2009 November; 37(20): 6831–6848. Published online 2009 November. doi: 10.1093/nar/gkp742.
PMCID: PMC2777425
RNA
Tertiary network in mammalian mitochondrial tRNAAsp revealed by solution probing and phylogeny
Marie Messmer, Joern Pütz, Takeo Suzuki, Tsutomu Suzuki, Claude Sauter, Marie Sissler, and Florentz Catherine
Nucleic Acids Res. 2009 November; 37(20): 6881–6895. Published online 2009 November. doi: 10.1093/nar/gkp697.
PMCID: PMC2777451
Translation of the FMR1 mRNA is not influenced by AGG interruptions
Anna L. Ludwig, Christopher Raske, Flora Tassone, Dolores Garcia-Arocena, John W. Hershey, and Paul J. Hagerman
Nucleic Acids Res. 2009 November; 37(20): 6896–6904. Published online 2009 November. doi: 10.1093/nar/gkp713.
PMCID: PMC2777427
Evidence for large diversity in the human transcriptome created by Alu RNA editing
Michal Barak, Erez Y. Levanon, Eli Eisenberg, Nurit Paz, Gideon Rechavi, George M. Church, and Ramit Mehr
Nucleic Acids Res. 2009 November; 37(20): 6905–6915. Published online 2009 November. doi: 10.1093/nar/gkp729.
PMCID: PMC2777429
Recognition and coupling of A-to-I edited sites are determined by the tertiary structure of the RNA
Mats Ensterö, Chammiran Daniel, Helene Wahlstedt, François Major, and Marie Öhman
Nucleic Acids Res. 2009 November; 37(20): 6916–6926. Published online 2009 November. doi: 10.1093/nar/gkp731.
PMCID: PMC2777444
Off-target and a portion of target-specific siRNA mediated mRNA degradation is Ago2 ‘Slicer’ independent and can be mediated by Ago1
Timothy A. Vickers, Walt F. Lima, Hongjiang Wu, Josh G. Nichols, Peter S. Linsley, and Stanley T. Crooke
Nucleic Acids Res. 2009 November; 37(20): 6927–6941. Published online 2009 November. doi: 10.1093/nar/gkp735.
PMCID: PMC2777430
Recognition of tRNAGln by Helicobacter pylori GluRS2—a tRNAGln-specific glutamyl-tRNA synthetase
Keng-Ming Chang and Tamara L. Hendrickson
Nucleic Acids Res. 2009 November; 37(20): 6942–6949. Published online 2009 November. doi: 10.1093/nar/gkp754.
PMCID: PMC2777447
The 5′-end heterogeneity of adenovirus virus-associated RNAI contributes to the asymmetric guide strand incorporation into the RNA-induced silencing complex
Ning Xu, Sofia Gkountela, Khalid Saeed, and Göran Akusjärvi
Nucleic Acids Res. 2009 November; 37(20): 6950–6959. Published online 2009 November. doi: 10.1093/nar/gkp764.
PMCID: PMC2777419
Structural Biology
The fragment structure of a putative HsdR subunit of a type I restriction enzyme from Vibrio vulnificus YJ016: implications for DNA restriction and translocation activity
Nguyen To Uyen, Suk-Youl Park, Ji-Woo Choi, Hyun-Ju Lee, Kosuke Nishi, and Jeong-Sun Kim
Nucleic Acids Res. 2009 November; 37(20): 6960–6969. Published online 2009 November. doi: 10.1093/nar/gkp603.
PMCID: PMC2777439
The Staphylococcus aureus pSK41 plasmid-encoded ArtA protein is a master regulator of plasmid transmission genes and contains a RHH motif used in alternate DNA-binding modes
Lisheng Ni, Slade O. Jensen, Nam Ky Tonthat, Tracey Berg, Stephen M. Kwong, Fiona H. X. Guan, Melissa H. Brown, Ronald A. Skurray, Neville Firth, and Maria A. Schumacher
Nucleic Acids Res. 2009 November; 37(20): 6970–6983. Published online 2009 November. doi: 10.1093/nar/gkp756.
PMCID: PMC2777438
Synthetic Biology and Chemistry
Synthesis of DNA fragments in yeast by one-step assembly of overlapping oligonucleotides
Daniel G. Gibson
Nucleic Acids Res. 2009 November; 37(20): 6984–6990. Published online 2009 November. doi: 10.1093/nar/gkp687.
PMCID: PMC2777417
Genomics
Genome-wide colonization of gene regulatory elements by G4 DNA motifs
Zhuo Du, Yiqiang Zhao, and Ning Li
Nucleic Acids Res. 2009 November; 37(20): 6784–6798. Published online 2009 November. doi: 10.1093/nar/gkp710.
PMCID: PMC2777415
Selection for minimization of translational frameshifting errors as a factor in the evolution of codon usage
Yang Huang, Eugene V. Koonin, David J. Lipman, and Teresa M. Przytycka
Nucleic Acids Res. 2009 November; 37(20): 6799–6810. Published online 2009 November. doi: 10.1093/nar/gkp712.
PMCID: PMC2777431
Methods Online
In vivo expression and purification of aptamer-tagged small RNA regulators
Nelly Said, Renate Rieder, Robert Hurwitz, Jochen Deckert, Henning Urlaub, and Jörg Vogel
Nucleic Acids Res. 2009 November; 37(20): e133. Published online 2009 November. doi: 10.1093/nar/gkp719.
PMCID: PMC2777422
Alternative-splicing-based bicistronic vectors for ratio-controlled protein expression and application to recombinant antibody production
Stéphanie Fallot, Raouia Ben Naya, Corinne Hieblot, Philippe Mondon, Eric Lacazette, Khalil Bouayadi, Abdelhakim Kharrat, Christian Touriol, and Hervé Prats
Nucleic Acids Res. 2009 November; 37(20): e134. Published online 2009 November. doi: 10.1093/nar/gkp716.
PMCID: PMC2777421
A generalized conformational energy function of DNA derived from molecular dynamics simulations
Satoshi Yamasaki, Tohru Terada, Kentaro Shimizu, Hidetoshi Kono, and Akinori Sarai
Nucleic Acids Res. 2009 November; 37(20): e135. Published online 2009 November. doi: 10.1093/nar/gkp718.
PMCID: PMC2777435
A high-resolution magnetic tweezer for single-molecule measurements
Kipom Kim and Omar A. Saleh
Nucleic Acids Res. 2009 November; 37(20): e136. Published online 2009 November. doi: 10.1093/nar/gkp725.
PMCID: PMC2777445
A high throughput experimental approach to identify miRNA targets in human cells
Lu Ping Tan, Erwin Seinen, Gerben Duns, Debora de Jong, Ody C. M. Sibon, Sibrand Poppema, Bart-Jan Kroesen, Klaas Kok, and Anke van den Berg
Nucleic Acids Res. 2009 November; 37(20): e137. Published online 2009 November. doi: 10.1093/nar/gkp715.
PMCID: PMC2777426
Computational Biology
FIGfams: yet another set of protein families
Folker Meyer, Ross Overbeek, and Alex Rodriguez
Nucleic Acids Res. 2009 November; 37(20): 6643–6654. Published online 2009 November. doi: 10.1093/nar/gkp698.
PMCID: PMC2777423
Nucleic Acid Enzymes
Evidence of the crucial role of the linker domain on the catalytic activity of human topoisomerase I by experimental and simulative characterization of the Lys681Ala mutant
Paola Fiorani, Cinzia Tesauro, Giordano Mancini, Giovanni Chillemi, Ilda D'A;nnessa, Grazia Graziani, Lucio Tentori, Alessia Muzi, and Alessandro Desideri
Nucleic Acids Res. 2009 November; 37(20): 6849–6858. Published online 2009 November. doi: 10.1093/nar/gkp669.
PMCID: PMC2777420
Time-resolved fluorescence studies of nucleotide flipping by restriction enzymes
Robert K. Neely, Gintautas Tamulaitis, Kai Chen, Marta Kubala, Virginijus Siksnys, and Anita C. Jones
Nucleic Acids Res. 2009 November; 37(20): 6859–6870. Published online 2009 November. doi: 10.1093/nar/gkp688.
PMCID: PMC2777440
High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display
Jordan Jarjour, Hoku West-Foyle, Michael T. Certo, Christopher G. Hubert, Lindsey Doyle, Melissa M. Getz, Barry L. Stoddard, and Andrew M. Scharenberg
Nucleic Acids Res. 2009 November; 37(20): 6871–6880. Published online 2009 November. doi: 10.1093/nar/gkp726.
PMCID: PMC2777416
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