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Front-Matter/Back-Matter Nucleic Acids Research: VOLUME 37 ISSUE 20 2009 Nucleic Acids Res. 2009 November; 37(20): i. Published online 2009 November. doi: 10.1093/nar/gkp1111.PMCID: PMC2777441 Nucleic Acids Res. 2009 November; 37(20): ii. Published online 2009 November. doi: 10.1093/nar/gkp1110.PMCID: PMC2777449 Nucleic Acids Res. 2009 November; 37(20): iii. Published online 2009 November. doi: 10.1093/nar/gkp1112.PMCID: PMC2777436 Gene Regulation, Chromatin and Epigenetics Transcription from bacteriophage λ pR promoter is regulated independently and antagonistically by DksA and ppGpp Robert Łyżeń, Maja Kochanowska, Grzegorz Węgrzyn, and Agnieszka Szalewska-Pałasz Nucleic Acids Res. 2009 November; 37(20): 6655–6664. Published online 2009 November. doi: 10.1093/nar/gkp676.PMCID: PMC2777414 The loss of histone H3 lysine 9 acetylation due to dSAGA-specific dAda2b mutation influences the expression of only a small subset of genes Nóra Zsindely, Tibor Pankotai, Zsuzsanna Újfaludi, Dániel Lakatos, Orbán Komonyi, László Bodai, László Tora, and Imre M. Boros Nucleic Acids Res. 2009 November; 37(20): 6665–6680. Published online 2009 November. doi: 10.1093/nar/gkp722.PMCID: PMC2777428 MeCP2/H3meK9 are involved in IL-6 gene silencing in pancreatic adenocarcinoma cell lines Mario Dandrea, Massimo Donadelli, Chiara Costanzo, Aldo Scarpa, and Marta Palmieri Nucleic Acids Res. 2009 November; 37(20): 6681–6690. Published online 2009 November. doi: 10.1093/nar/gkp723.PMCID: PMC2777443 GSK3β is a negative regulator of the transcriptional coactivator MAML1 Mariana Saint Just Ribeiro, Magnus L. Hansson, Mikael J. Lindberg, Anita E. Popko-Ścibor, and Annika E. Wallberg Nucleic Acids Res. 2009 November; 37(20): 6691–6700. Published online 2009 November. doi: 10.1093/nar/gkp724.PMCID: PMC2777432 In vivo methylation of mtDNA reveals the dynamics of protein–mtDNA interactions Adriana P. Rebelo, Sion L. Williams, and Carlos T. Moraes Nucleic Acids Res. 2009 November; 37(20): 6701–6715. Published online 2009 November. doi: 10.1093/nar/gkp727.PMCID: PMC2777446 Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression Himesh Fernando, Sven Sewitz, Jeremy Darot, Simon Tavaré, Julian Leon Huppert, and Shankar Balasubramanian Nucleic Acids Res. 2009 November; 37(20): 6716–6722. Published online 2009 November. doi: 10.1093/nar/gkp740.PMCID: PMC2777450 Regulation of transcription termination in the nematode Caenorhabditis elegans Simon Haenni, Helen E. Sharpe, Maria Gravato Nobre, Kerstin Zechner, Cathy Browne, Jonathan Hodgkin, and André Furger Nucleic Acids Res. 2009 November; 37(20): 6723–6736. Published online 2009 November. doi: 10.1093/nar/gkp744.PMCID: PMC2777434 Genome Integrity, Repair and Replication Translesion DNA synthesis-assisted non-homologous end-joining of complex double-strand breaks prevents loss of DNA sequences in mammalian cells Shay Covo, Jean-Pierre de Villartay, Penny A. Jeggo, and Zvi Livneh Nucleic Acids Res. 2009 November; 37(20): 6737–6745. Published online 2009 November. doi: 10.1093/nar/gkp703.PMCID: PMC2777433 Involvement of p54(nrb), a PSF partner protein, in DNA double-strand break repair and radioresistance Shuyi Li, Wendy W. Kuhne, Anita Kulharya, Farlyn Z. Hudson, Kyungsoo Ha, Zhen Cao, and William S. Dynan Nucleic Acids Res. 2009 November; 37(20): 6746–6753. Published online 2009 November. doi: 10.1093/nar/gkp741.PMCID: PMC2777424 Functional significance of the Rad51-Srs2 complex in Rad51 presynaptic filament disruption Sierra Colavito, Margaret Macris-Kiss, Changhyun Seong, Olive Gleeson, Eric C. Greene, Hannah L. Klein, Lumir Krejci, and Patrick Sung Nucleic Acids Res. 2009 November; 37(20): 6754–6764. Published online 2009 November. doi: 10.1093/nar/gkp748.PMCID: PMC2777448 Biophysical characterizations of human mitochondrial transcription factor A and its binding to tumor suppressor p53 Tuck Seng Wong, Sridharan Rajagopalan, Stefan M. Freund, Trevor J. Rutherford, Antonina Andreeva, Fiona M. Townsley, Miriana Petrovich, and Alan R. Fersht Nucleic Acids Res. 2009 November; 37(20): 6765–6783. Published online 2009 November. doi: 10.1093/nar/gkp750.PMCID: PMC2777442 Molecular Biology Predictable suppression of gene expression by 5′-UTR-based RNA quadruplexes Kangkan Halder, Markus Wieland, and Jörg S. Hartig Nucleic Acids Res. 2009 November; 37(20): 6811–6817. Published online 2009 November. doi: 10.1093/nar/gkp696.PMCID: PMC2777418 Characterization of RNA aptamers that disrupt the RUNX1–CBFβ/DNA complex Jenny L. Barton, David H. J. Bunka, Stuart E. Knowling, Pascal Lefevre, Alan J. Warren, Constanze Bonifer, and Peter G. Stockley Nucleic Acids Res. 2009 November; 37(20): 6818–6830. Published online 2009 November. doi: 10.1093/nar/gkp728.PMCID: PMC2777437 DNA translocation activity of the multifunctional replication protein ORF904 from the archaeal plasmid pRN1 Martin Sanchez, Markus Drechsler, Holger Stark, and Georg Lipps Nucleic Acids Res. 2009 November; 37(20): 6831–6848. Published online 2009 November. doi: 10.1093/nar/gkp742.PMCID: PMC2777425 RNA Tertiary network in mammalian mitochondrial tRNAAsp revealed by solution probing and phylogeny Marie Messmer, Joern Pütz, Takeo Suzuki, Tsutomu Suzuki, Claude Sauter, Marie Sissler, and Florentz Catherine Nucleic Acids Res. 2009 November; 37(20): 6881–6895. Published online 2009 November. doi: 10.1093/nar/gkp697.PMCID: PMC2777451 Translation of the FMR1 mRNA is not influenced by AGG interruptions Anna L. Ludwig, Christopher Raske, Flora Tassone, Dolores Garcia-Arocena, John W. Hershey, and Paul J. Hagerman Nucleic Acids Res. 2009 November; 37(20): 6896–6904. Published online 2009 November. doi: 10.1093/nar/gkp713.PMCID: PMC2777427 Evidence for large diversity in the human transcriptome created by Alu RNA editing Michal Barak, Erez Y. Levanon, Eli Eisenberg, Nurit Paz, Gideon Rechavi, George M. Church, and Ramit Mehr Nucleic Acids Res. 2009 November; 37(20): 6905–6915. Published online 2009 November. doi: 10.1093/nar/gkp729.PMCID: PMC2777429 Recognition and coupling of A-to-I edited sites are determined by the tertiary structure of the RNA Mats Ensterö, Chammiran Daniel, Helene Wahlstedt, François Major, and Marie Öhman Nucleic Acids Res. 2009 November; 37(20): 6916–6926. Published online 2009 November. doi: 10.1093/nar/gkp731.PMCID: PMC2777444 Off-target and a portion of target-specific siRNA mediated mRNA degradation is Ago2 ‘Slicer’ independent and can be mediated by Ago1 Timothy A. Vickers, Walt F. Lima, Hongjiang Wu, Josh G. Nichols, Peter S. Linsley, and Stanley T. Crooke Nucleic Acids Res. 2009 November; 37(20): 6927–6941. Published online 2009 November. doi: 10.1093/nar/gkp735.PMCID: PMC2777430 Recognition of tRNAGln by Helicobacter pylori GluRS2—a tRNAGln-specific glutamyl-tRNA synthetase Keng-Ming Chang and Tamara L. Hendrickson Nucleic Acids Res. 2009 November; 37(20): 6942–6949. Published online 2009 November. doi: 10.1093/nar/gkp754.PMCID: PMC2777447 The 5′-end heterogeneity of adenovirus virus-associated RNAI contributes to the asymmetric guide strand incorporation into the RNA-induced silencing complex Ning Xu, Sofia Gkountela, Khalid Saeed, and Göran Akusjärvi Nucleic Acids Res. 2009 November; 37(20): 6950–6959. Published online 2009 November. doi: 10.1093/nar/gkp764.PMCID: PMC2777419 Structural Biology The fragment structure of a putative HsdR subunit of a type I restriction enzyme from Vibrio vulnificus YJ016: implications for DNA restriction and translocation activity Nguyen To Uyen, Suk-Youl Park, Ji-Woo Choi, Hyun-Ju Lee, Kosuke Nishi, and Jeong-Sun Kim Nucleic Acids Res. 2009 November; 37(20): 6960–6969. Published online 2009 November. doi: 10.1093/nar/gkp603.PMCID: PMC2777439 The Staphylococcus aureus pSK41 plasmid-encoded ArtA protein is a master regulator of plasmid transmission genes and contains a RHH motif used in alternate DNA-binding modes Lisheng Ni, Slade O. Jensen, Nam Ky Tonthat, Tracey Berg, Stephen M. Kwong, Fiona H. X. Guan, Melissa H. Brown, Ronald A. Skurray, Neville Firth, and Maria A. Schumacher Nucleic Acids Res. 2009 November; 37(20): 6970–6983. Published online 2009 November. doi: 10.1093/nar/gkp756.PMCID: PMC2777438 Synthetic Biology and Chemistry Synthesis of DNA fragments in yeast by one-step assembly of overlapping oligonucleotides Daniel G. Gibson Nucleic Acids Res. 2009 November; 37(20): 6984–6990. Published online 2009 November. doi: 10.1093/nar/gkp687.PMCID: PMC2777417 Genomics Genome-wide colonization of gene regulatory elements by G4 DNA motifs Zhuo Du, Yiqiang Zhao, and Ning Li Nucleic Acids Res. 2009 November; 37(20): 6784–6798. Published online 2009 November. doi: 10.1093/nar/gkp710.PMCID: PMC2777415 Selection for minimization of translational frameshifting errors as a factor in the evolution of codon usage Yang Huang, Eugene V. Koonin, David J. Lipman, and Teresa M. Przytycka Nucleic Acids Res. 2009 November; 37(20): 6799–6810. Published online 2009 November. doi: 10.1093/nar/gkp712.PMCID: PMC2777431 Methods Online In vivo expression and purification of aptamer-tagged small RNA regulators Nelly Said, Renate Rieder, Robert Hurwitz, Jochen Deckert, Henning Urlaub, and Jörg Vogel Nucleic Acids Res. 2009 November; 37(20): e133. Published online 2009 November. doi: 10.1093/nar/gkp719.PMCID: PMC2777422 Alternative-splicing-based bicistronic vectors for ratio-controlled protein expression and application to recombinant antibody production Stéphanie Fallot, Raouia Ben Naya, Corinne Hieblot, Philippe Mondon, Eric Lacazette, Khalil Bouayadi, Abdelhakim Kharrat, Christian Touriol, and Hervé Prats Nucleic Acids Res. 2009 November; 37(20): e134. Published online 2009 November. doi: 10.1093/nar/gkp716.PMCID: PMC2777421 A generalized conformational energy function of DNA derived from molecular dynamics simulations Satoshi Yamasaki, Tohru Terada, Kentaro Shimizu, Hidetoshi Kono, and Akinori Sarai Nucleic Acids Res. 2009 November; 37(20): e135. Published online 2009 November. doi: 10.1093/nar/gkp718.PMCID: PMC2777435 A high-resolution magnetic tweezer for single-molecule measurements Kipom Kim and Omar A. Saleh Nucleic Acids Res. 2009 November; 37(20): e136. Published online 2009 November. doi: 10.1093/nar/gkp725.PMCID: PMC2777445 A high throughput experimental approach to identify miRNA targets in human cells Lu Ping Tan, Erwin Seinen, Gerben Duns, Debora de Jong, Ody C. M. Sibon, Sibrand Poppema, Bart-Jan Kroesen, Klaas Kok, and Anke van den Berg Nucleic Acids Res. 2009 November; 37(20): e137. Published online 2009 November. doi: 10.1093/nar/gkp715.PMCID: PMC2777426 Computational Biology FIGfams: yet another set of protein families Folker Meyer, Ross Overbeek, and Alex Rodriguez Nucleic Acids Res. 2009 November; 37(20): 6643–6654. Published online 2009 November. doi: 10.1093/nar/gkp698.PMCID: PMC2777423 Nucleic Acid Enzymes Evidence of the crucial role of the linker domain on the catalytic activity of human topoisomerase I by experimental and simulative characterization of the Lys681Ala mutant Paola Fiorani, Cinzia Tesauro, Giordano Mancini, Giovanni Chillemi, Ilda D'A;nnessa, Grazia Graziani, Lucio Tentori, Alessia Muzi, and Alessandro Desideri Nucleic Acids Res. 2009 November; 37(20): 6849–6858. Published online 2009 November. doi: 10.1093/nar/gkp669.PMCID: PMC2777420 Time-resolved fluorescence studies of nucleotide flipping by restriction enzymes Robert K. Neely, Gintautas Tamulaitis, Kai Chen, Marta Kubala, Virginijus Siksnys, and Anita C. Jones Nucleic Acids Res. 2009 November; 37(20): 6859–6870. Published online 2009 November. doi: 10.1093/nar/gkp688.PMCID: PMC2777440 High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display Jordan Jarjour, Hoku West-Foyle, Michael T. Certo, Christopher G. Hubert, Lindsey Doyle, Melissa M. Getz, Barry L. Stoddard, and Andrew M. Scharenberg Nucleic Acids Res. 2009 November; 37(20): 6871–6880. Published online 2009 November. doi: 10.1093/nar/gkp726.PMCID: PMC2777416
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