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Volume 178(5);  May 2011

This month in AJP

This Month in AJP
Am J Pathol. 2011 May; 178(5): 1931. doi: 10.1016/j.ajpath.2011.03.001
PMCID:
PMC3081160
Full Text PDF–65K

Mini-Reviews

The Pathoetiology of Neurofibromatosis 1
Eeva-Mari Jouhilahti, Sirkku Peltonen, Anthony M. Heape, Juha Peltonen
Am J Pathol. 2011 May; 178(5): 1932–1939. doi: 10.1016/j.ajpath.2010.12.056
PMCID:
PMC3081157
Abstract Full Text PDF–586K
Importance of Molecular Features of Non–Small Cell Lung Cancer for Choice of Treatment
Cesar Moran
Am J Pathol. 2011 May; 178(5): 1940–1948. doi: 10.1016/j.ajpath.2010.12.057
PMCID:
PMC3081153
Abstract Full Text PDF–618K

Commentary

Mitochondrial Biogenesis Drives Tumor Cell Proliferation
Ubaldo E. Martinez-Outschoorn, Stephanos Pavlides, Federica Sotgia, Michael P. Lisanti
Am J Pathol. 2011 May; 178(5): 1949–1952. doi: 10.1016/j.ajpath.2011.03.002
PMCID:
PMC3081148
Full Text PDF–757K

Regular Articles

Biomarkers, Genomics, Proteomics, and Gene Regulation

Aberrant Expression of Retinoic Acid Signaling Molecules Influences Patient Survival in Astrocytic Gliomas
Benito Campos, Franz-Simon Centner, Justo Lorenzo Bermejo, Ramadan Ali, Katharina Dorsch, Feng Wan, Jörg Felsberg, Rezvan Ahmadi, Niels Grabe, Guido Reifenberger, Andreas Unterberg, Jürgen Burhenne, Christel Herold-Mende
Am J Pathol. 2011 May; 178(5): 1953–1964. doi: 10.1016/j.ajpath.2011.01.051
PMCID:
PMC3081142
Abstract Full Text PDF–4.0M Supplementary Material
Hypermethylation of a Cluster of Krüppel-Type Zinc Finger Protein Genes on Chromosome 19q13 in Oropharyngeal Squamous Cell Carcinoma
Roberto A. Lleras, Leslie R. Adrien, Richard V. Smith, Benjamin Brown, Naheed Jivraj, Christopher Keller, Cathy Sarta, Nicolas F. Schlecht, Thomas M. Harris, Geoffrey Childs, Michael B. Prystowsky, Thomas J. Belbin
Am J Pathol. 2011 May; 178(5): 1965–1974. doi: 10.1016/j.ajpath.2011.01.049
PMCID:
PMC3081156
Abstract Full Text PDF–1.3M Supplementary Material
Osteopontin Modulates Inflammation, Mucin Production, and Gene Expression Signatures After Inhalation of Asbestos in a Murine Model of Fibrosis
Tara Sabo-Attwood, Maria E. Ramos-Nino, Maria Eugenia-Ariza, Maximilian B. MacPherson, Kelly J. Butnor, Pamela C. Vacek, Sean P. McGee, Jessica C. Clark, Chad Steele, Brooke T. Mossman
Am J Pathol. 2011 May; 178(5): 1975–1985. doi: 10.1016/j.ajpath.2011.01.048
PMCID:
PMC3081197
Abstract Full Text PDF–1.8M
Tissue Microarray Cytometry Reveals Positive Impact of Homeodomain Interacting Protein Kinase 2 in Colon Cancer Survival Irrespective of p53 Function
Isabelle Soubeyran, Isabelle Mahouche, Aude Grigoletto, Thierry Leste-Lasserre, Guillaume Drutel, Christophe Rey, Stephane Pedeboscq, France Blanchard, Veronique Brouste, Jean-Christophe Sabourin, Yves Bécouarn, Josy Reiffers, François Ichas, Francesca De Giorgi
Am J Pathol. 2011 May; 178(5): 1986–1998. doi: 10.1016/j.ajpath.2011.01.021
PMCID:
PMC3081143
Abstract Full Text PDF–2.5M Supplementary Material

Cardiovascular, Pulmonary, and Renal Pathology

A Murine Model of Phosphate Nephropathy
Philipp Eller, Kathrin Eller, Alexander H. Kirsch, Josef J. Patsch, Anna M. Wolf, Andrea Tagwerker, Ursula Stanzl, Reinhard Kaindl, Volker Kahlenberg, Gert Mayer, Josef R. Patsch, Alexander R. Rosenkranz
Am J Pathol. 2011 May; 178(5): 1999–2006. doi: 10.1016/j.ajpath.2011.01.024
PMCID:
PMC3081192
Abstract Full Text PDF–2.1M
Diminished Met Signaling in Podocytes Contributes to the Development of Podocytopenia in Transplant Glomerulopathy
Putri A. Agustian, Mario Schiffer, Wilfried Gwinner, Irini Schäfer, Katharina Theophile, Friedrich Modde, Clemens L. Bockmeyer, Jana Traeder, Ulrich Lehmann, Anika Groβhennig, Hans H. Kreipe, Verena Bröcker, Jan U. Becker
Am J Pathol. 2011 May; 178(5): 2007–2019. doi: 10.1016/j.ajpath.2011.01.042
PMCID:
PMC3081204
Abstract Full Text PDF–1.7M
Mitochondrial Dysfunction Mediates Aldosterone-Induced Podocyte Damage: A Therapeutic Target of PPARγ
Chunhua Zhu, Songming Huang, Yanggang Yuan, Guixia Ding, Ronghua Chen, Bicheng Liu, Tianxin Yang, Aihua Zhang
Am J Pathol. 2011 May; 178(5): 2020–2031. doi: 10.1016/j.ajpath.2011.01.029
PMCID:
PMC3081205
Abstract Full Text PDF–2.8M

Cell Injury, Repair, Aging, and Apoptosis

N-Acetylcysteine Amide (NACA) Prevents Retinal Degeneration by Up-Regulating Reduced Glutathione Production and Reversing Lipid Peroxidation
Andrew M. Schimel, Linu Abraham, Douglas Cox, Abdoulaye Sene, Courtney Kraus, Dru S. Dace, Nuran Ercal, Rajendra S. Apte
Am J Pathol. 2011 May; 178(5): 2032–2043. doi: 10.1016/j.ajpath.2011.01.036
PMCID:
PMC3081196
Abstract Full Text PDF–2.2M
Ubiquitin C-Terminal Hydrolase-L1 Activity Induces Polyubiquitin Accumulation in Podocytes and Increases Proteinuria in Rat Membranous Nephropathy
Catherine Meyer-Schwesinger, Tobias N. Meyer, Henning Sievert, Elion Hoxha, Marlies Sachs, Eva-Maria Klupp, Silvia Münster, Stefan Balabanov, Lucie Carrier, Udo Helmchen, Friedrich Thaiss, Rolf A.K. Stahl
Am J Pathol. 2011 May; 178(5): 2044–2057. doi: 10.1016/j.ajpath.2011.01.017
PMCID:
PMC3081162
Abstract Full Text PDF–4.6M Supplementary Material

Epithelial and Mesenchymal Cell Biology

Dry Eye Symptoms Are Increased in Mice Deficient in Phospholipid Transfer Protein (PLTP)
Niko L. Setälä, Jari Metso, Matti Jauhiainen, Antti Sajantila, Juha M. Holopainen
Am J Pathol. 2011 May; 178(5): 2058–2065. doi: 10.1016/j.ajpath.2011.01.027
PMCID:
PMC3081166
Abstract Full Text PDF–1.5M
Aberrant Cell Proliferation by Enhanced Mitochondrial Biogenesis via mtTFA in Arsenical Skin Cancers
Chih-Hung Lee, Shi-Bei Wu, Chien-Hui Hong, Wei-Ting Liao, Ching-Ying Wu, Gwo-Shing Chen, Yau-Huei Wei, Hsin-Su Yu
Am J Pathol. 2011 May; 178(5): 2066–2076. doi: 10.1016/j.ajpath.2011.01.056
PMCID:
PMC3081159
Abstract Full Text PDF–1.6M
The Early Growth Response Gene Egr2 (Alias Krox20) Is a Novel Transcriptional Target of Transforming Growth Factor-β that Is Up-Regulated in Systemic Sclerosis and Mediates Profibrotic Responses
Feng Fang, Kohtaro Ooka, Swati Bhattachyya, Jun Wei, Minghua Wu, Pan Du, Simon Lin, Francesco Del Galdo, Carol A. Feghali-Bostwick, John Varga
Am J Pathol. 2011 May; 178(5): 2077–2090. doi: 10.1016/j.ajpath.2011.01.035
PMCID:
PMC3081194
Abstract Full Text PDF–3.0M Supplementary Material
Type 2 Helper T-Cell Cytokines Induce Morphologic and Molecular Characteristics of Atopic Dermatitis in Human Skin Equivalent
Marijke Kamsteeg, Mieke Bergers, Roelie de Boer, Patrick L.J.M. Zeeuwen, Stanleyson V. Hato, Joost Schalkwijk, Geuranne S. Tjabringa
Am J Pathol. 2011 May; 178(5): 2091–2099. doi: 10.1016/j.ajpath.2011.01.037
PMCID:
PMC3081201
Abstract Full Text PDF–1.5M

Gastrointestinal, Hepatobiliary, and Pancreatic Pathology

Thymosin-β4 (Tβ4) Blunts PDGF-Dependent Phosphorylation and Binding of AKT to Actin in Hepatic Stellate Cells
Karina Reyes-Gordillo, Ruchi Shah, Anastas Popratiloff, Sidney Fu, Anna Hindle, Frederick Brody, Marcos Rojkind
Am J Pathol. 2011 May; 178(5): 2100–2108. doi: 10.1016/j.ajpath.2011.01.025
PMCID:
PMC3081167
Abstract Full Text PDF–1.7M Supplementary Material
Bortezomib Stabilizes Mitotic Cyclins and Prevents Cell Cycle Progression via Inhibition of UBE2C in Colorectal Carcinoma
Prashant Bavi, Shahab Uddin, Maqbool Ahmed, Zeenath Jehan, Rong Bu, Jehad Abubaker, Mehar Sultana, Nasser Al-Sanea, Alaa Abduljabbar, Luai H. Ashari, Samar Alhomoud, Fouad Al-Dayel, Sarita Prabhakaran, Azhar R. Hussain, Khawla S. Al-Kuraya
Am J Pathol. 2011 May; 178(5): 2109–2120. doi: 10.1016/j.ajpath.2011.01.034
PMCID:
PMC3081207
Abstract Full Text PDF–2.1M Supplementary Material

Immunopathology and Infectious Disease

Recently Infiltrating MAC387+ Monocytes/Macrophages: A Third Macrophage Population Involved in SIV and HIV Encephalitic Lesion Formation
Caroline Soulas, Cecily Conerly, Woong-Ki Kim, Tricia H. Burdo, Xavier Alvarez, Andrew A. Lackner, Kenneth C. Williams
Am J Pathol. 2011 May; 178(5): 2121–2135. doi: 10.1016/j.ajpath.2011.01.023
PMCID:
PMC3081227
Abstract Full Text PDF–7.0M
A2A Adenosine Receptor (A2AAR) as a Therapeutic Target in Diabetic Retinopathy
Ahmed S. Ibrahim, Mamdouh M. El-shishtawy, Wenbo Zhang, Ruth B. Caldwell, Gregory I. Liou
Am J Pathol. 2011 May; 178(5): 2136–2145. doi: 10.1016/j.ajpath.2011.01.018
PMCID:
PMC3081155
Abstract Full Text PDF–2.5M
The Neuropathology of Fatal Cerebral Malaria in Malawian Children
Katerina Dorovini-Zis, Kristopher Schmidt, Hanh Huynh, Wenjiang Fu, Richard O. Whitten, Dan Milner, Steve Kamiza, Malcolm Molyneux, Terrie E. Taylor
Am J Pathol. 2011 May; 178(5): 2146–2158. doi: 10.1016/j.ajpath.2011.01.016
PMCID:
PMC3081150
Abstract Full Text PDF–5.3M
SPLUNC1 Promotes Lung Innate Defense Against Mycoplasma pneumoniae Infection in Mice
Fabienne Gally, Y. Peter Di, Sean K. Smith, Maisha N. Minor, Yang Liu, Donna L. Bratton, S. Courtney Frasch, Nicole M. Michels, Stephanie R. Case, Hong Wei Chu
Am J Pathol. 2011 May; 178(5): 2159–2167. doi: 10.1016/j.ajpath.2011.01.026
PMCID:
PMC3081195
Abstract Full Text PDF–1.3M
Dermatan Sulfate Interacts with Dead Cells and Regulates CD5+ B-Cell Fate: Implications for a Key Role in Autoimmunity
Julia Y. Wang, Jongmin Lee, Ming Yan, Jung-hyun Rho, Michael H.A. Roehrl
Am J Pathol. 2011 May; 178(5): 2168–2176. doi: 10.1016/j.ajpath.2011.01.028
PMCID:
PMC3081202
Abstract Full Text PDF–1.8M Supplementary Material
Human Proteins with Affinity for Dermatan Sulfate Have the Propensity to Become Autoantigens
Jung-hyun Rho, Wei Zhang, Mandakolathur Murali, Michael H.A. Roehrl, Julia Y. Wang
Am J Pathol. 2011 May; 178(5): 2177–2190. doi: 10.1016/j.ajpath.2011.01.031
PMCID:
PMC3081203
Abstract Full Text PDF–1.9M Supplementary Material
Overexpression of Dominant Negative Peroxisome Proliferator-Activated Receptor-γ (PPARγ) in Alveolar Type II Epithelial Cells Causes Inflammation and T-Cell Suppression in the Lung
Lingyan Wu, Guixue Wang, Peng Qu, Cong Yan, Hong Du
Am J Pathol. 2011 May; 178(5): 2191–2204. doi: 10.1016/j.ajpath.2011.01.046
PMCID:
PMC3081168
Abstract Full Text PDF–2.7M Supplementary Material

Metabolic, Endocrine, and Genitourinary Pathobiology

Long-Term Administration of the Histone Deacetylase Inhibitor Vorinostat Attenuates Renal Injury in Experimental Diabetes through an Endothelial Nitric Oxide Synthase-Dependent Mechanism
Andrew Advani, Qingling Huang, Kerri Thai, Suzanne L. Advani, Kathryn E. White, Darren J. Kelly, Darren A. Yuen, Kim A. Connelly, Philip A. Marsden, Richard E. Gilbert
Am J Pathol. 2011 May; 178(5): 2205–2214. doi: 10.1016/j.ajpath.2011.01.044
PMCID:
PMC3081208
Abstract Full Text PDF–2.7M

Metabolic, Endocrine, and Genitourinary Pathogiology

Impaired Biomechanical Properties of Diabetic Skin: Implications in Pathogenesis of Diabetic Wound Complications
Dustin M. Bermudez, Benjamin J. Herdrich, Junwang Xu, Robert Lind, David P. Beason, Marc E. Mitchell, Louis J. Soslowsky, Kenneth W. Liechty
Am J Pathol. 2011 May; 178(5): 2215–2223. doi: 10.1016/j.ajpath.2011.01.015
PMCID:
PMC3081147
Abstract Full Text PDF–1.6M

Molecular Pathogenesis of Genetic and Inherited Disease

Increased Expression of Wild-Type or a Centronuclear Myopathy Mutant of Dynamin 2 in Skeletal Muscle of Adult Mice Leads to Structural Defects and Muscle Weakness
Belinda S. Cowling, Anne Toussaint, Leonela Amoasii, Pascale Koebel, Arnaud Ferry, Laurianne Davignon, Ichizo Nishino, Jean-Louis Mandel, Jocelyn Laporte
Am J Pathol. 2011 May; 178(5): 2224–2235. doi: 10.1016/j.ajpath.2011.01.054
PMCID:
PMC3081151
Abstract Full Text PDF–3.4M Supplementary Material
Transcriptional Repression of Caveolin-1 (CAV1) Gene Expression by GATA-6 in Bladder Smooth Muscle Hypertrophy in Mice and Human Beings
Ettickan Boopathi, Cristiano Mendes Gomes, Robert Goldfarb, Mary John, Vittala Gopal Srinivasan, Jaber Alanzi, S. Bruce Malkowicz, Hasmeena Kathuria, Stephen A. Zderic, Alan J. Wein, Samuel Chacko
Am J Pathol. 2011 May; 178(5): 2236–2251. doi: 10.1016/j.ajpath.2011.01.038
PMCID:
PMC3081182
Abstract Full Text PDF–3.2M
Filaggrin Genotype in Ichthyosis Vulgaris Predicts Abnormalities in Epidermal Structure and Function
Robert Gruber, Peter M. Elias, Debra Crumrine, Tzu-Kai Lin, Johanna M. Brandner, Jean-Pierre Hachem, Richard B. Presland, Philip Fleckman, Andreas R. Janecke, Aileen Sandilands, W.H. Irwin McLean, Peter O. Fritsch, Michael Mildner, Erwin Tschachler, Matthias Schmuth
Am J Pathol. 2011 May; 178(5): 2252–2263. doi: 10.1016/j.ajpath.2011.01.053
PMCID:
PMC3081164
Abstract Full Text PDF–2.9M Supplementary Material

Neurobiology

Induction of Ischemic Tolerance Protects the Retina From Diabetic Retinopathy
Diego C. Fernandez, Pablo H. Sande, Mónica S. Chianelli, Hernán J. Aldana Marcos, Ruth E. Rosenstein
Am J Pathol. 2011 May; 178(5): 2264–2274. doi: 10.1016/j.ajpath.2011.01.040
PMCID:
PMC3081181
Abstract Full Text PDF–3.5M
Tyrosine Nitration within the Proline-Rich Region of Tau in Alzheimer's Disease
Juan F. Reyes, Yifan Fu, Laurel Vana, Nicholas M. Kanaan, Lester I. Binder
Am J Pathol. 2011 May; 178(5): 2275–2285. doi: 10.1016/j.ajpath.2011.01.030
PMCID:
PMC3081178
Abstract Full Text PDF–2.8M Supplementary Material
Observations in APP Bitransgenic Mice Suggest that Diffuse and Compact Plaques Form via Independent Processes in Alzheimer's Disease
Anna Lord, Ola Philipson, Therése Klingstedt, Gunilla Westermark, Per Hammarström, K. Peter R. Nilsson, Lars N.G. Nilsson
Am J Pathol. 2011 May; 178(5): 2286–2298. doi: 10.1016/j.ajpath.2011.01.052
PMCID:
PMC3081149
Abstract Full Text PDF–3.4M Supplementary Material

Stem Cells, Tissue Engineering, and Hematopoietic Elements

Adipose Tissue-Derived Stem Cell in Vitro Differentiation in a Three-Dimensional Dental Bud Structure
Federico Ferro, Renza Spelat, Giuseppe Falini, Annarita Gallelli, Federica D'Aurizio, Elisa Puppato, Maura Pandolfi, Antonio Paolo Beltrami, Daniela Cesselli, Carlo Alberto Beltrami, Francesco Saverio Ambesi-Impiombato, Francesco Curcio
Am J Pathol. 2011 May; 178(5): 2299–2310. doi: 10.1016/j.ajpath.2011.01.055
PMCID:
PMC3081158
Abstract Full Text PDF–5.5M Supplementary Material
Lack of TNF-α–Induced MMP-9 Production and Abnormal E-Cadherin Redistribution Associated with Compromised Fusion in MCP-1–Null Macrophages
Eleni A. Skokos, Antonios Charokopos, Khadija Khan, Jackie Wanjala, Themis R. Kyriakides
Am J Pathol. 2011 May; 178(5): 2311–2321. doi: 10.1016/j.ajpath.2011.01.045
PMCID:
PMC3081180
Abstract Full Text PDF–2.1M Supplementary Material
Adipose Injury–Associated Factors Mitigate Hypoxia in Ischemic Tissues through Activation of Adipose-Derived Stem/Progenitor/Stromal Cells and Induction of Angiogenesis
Hitomi Eto, Hirotaka Suga, Keita Inoue, Noriyuki Aoi, Harunosuke Kato, Jun Araki, Kentaro Doi, Takuya Higashino, Kotaro Yoshimura
Am J Pathol. 2011 May; 178(5): 2322–2332. doi: 10.1016/j.ajpath.2011.01.032
PMCID:
PMC3081200
Abstract Full Text PDF–3.2M Supplementary Material
Protein Phosphatase 2A Catalytic Subunit α (PP2Acα) Maintains Survival of Committed Erythroid Cells in Fetal Liver Erythropoiesis through the STAT5 Pathway
Weiqian Chen, Pengyu Gu, Xuan Jiang, Hai-Bin Ruan, Chaojun Li, Xiang Gao
Am J Pathol. 2011 May; 178(5): 2333–2343. doi: 10.1016/j.ajpath.2011.01.041
PMCID:
PMC3081176
Abstract Full Text PDF–2.1M Supplementary Material

Tumorigenesis and Neoplastic Progression

Identification of Oncostatin M as a STAT5-Dependent Mediator of Bone Marrow Remodeling in KIT D816V-Positive Systemic Mastocytosis
Gregor Hoermann, Sabine Cerny-Reiterer, Andrea Perné, Miriam Klauser, Konrad Hoetzenecker, Katharina Klein, Leonhard Müllauer, Marion Gröger, Sebastian M.B. Nijman, Walter Klepetko, Peter Valent, Matthias Mayerhofer
Am J Pathol. 2011 May; 178(5): 2344–2356. doi: 10.1016/j.ajpath.2011.01.020
PMCID:
PMC3081146
Abstract Full Text PDF–2.9M Supplementary Material
Selection of Brain Metastasis-Initiating Breast Cancer Cells Determined by Growth on Hard Agar
Lixia Guo, Dominic Fan, Fahao Zhang, Janet E. Price, Ju-Seog Lee, Dario Marchetti, Isaiah J. Fidler, Robert R. Langley
Am J Pathol. 2011 May; 178(5): 2357–2366. doi: 10.1016/j.ajpath.2011.01.047
PMCID:
PMC3081177
Abstract Full Text PDF–1.5M Supplementary Material
Skp2 Overexpression Is Associated with Loss of BRCA2 Protein in Human Prostate Cancer
Arnaldo A. Arbini, Margherita Greco, Jorge L. Yao, Patricia Bourne, Ersilia Marra, Jer-Tsong Hsieh, Paul A. di Sant'Agnese, Loredana Moro
Am J Pathol. 2011 May; 178(5): 2367–2376. doi: 10.1016/j.ajpath.2011.01.050
PMCID:
PMC3081144
Abstract Full Text PDF–1.7M Supplementary Material
CCN3 Impairs Osteoblast and Stimulates Osteoclast Differentiation to Favor Breast Cancer Metastasis to Bone
Véronique Ouellet, Kerstin Tiedemann, Anna Mourskaia, Jenna E. Fong, Danh Tran-Thanh, Eitan Amir, Mark Clemons, Bernard Perbal, Svetlana V. Komarova, Peter M. Siegel
Am J Pathol. 2011 May; 178(5): 2377–2388. doi: 10.1016/j.ajpath.2011.01.033
PMCID:
PMC3081179
Abstract Full Text PDF–2.4M Supplementary Material
S100A4 Expression in Xenograft Tumors of Human Carcinoma Cell Lines Is Induced by the Tumor Microenvironment
Hilde Ljones Wetting, Elin Hadler-Olsen, Synnøve Magnussen, Oddveig Rikardsen, Sonja E. Steigen, Elisabeth Sundkvist, Thrina Loennechen, Premasany Kanapathippillai, Hanne Kildalsen, Jan-Olof Winberg, Lars Uhlin-Hansen, Gunbjørg Svineng
Am J Pathol. 2011 May; 178(5): 2389–2396. doi: 10.1016/j.ajpath.2011.01.022
PMCID:
PMC3081199
Abstract Full Text PDF–1.5M Supplementary Material
Pirin Inhibits Cellular Senescence in Melanocytic Cells
Silvia Licciulli, Chiara Luise, Gaia Scafetta, Maria Capra, Giuseppina Giardina, Paolo Nuciforo, Silvano Bosari, Giuseppe Viale, Giovanni Mazzarol, Chiara Tonelli, Luisa Lanfrancone, Myriam Alcalay
Am J Pathol. 2011 May; 178(5): 2397–2406. doi: 10.1016/j.ajpath.2011.01.019
PMCID:
PMC3081152
Abstract Full Text PDF–2.0M Supplementary Material
Overexpression of a Chromatin Remodeling Factor, RSF-1/HBXAP, Correlates with Aggressive Oral Squamous Cell Carcinoma
Fu-Min Fang, Chien-Feng Li, Hsuan-Ying Huang, Ming-Tsong Lai, Chih-Mei Chen, I-Wen Chiu, Tian-Li Wang, Fuu-Jen Tsai, Ie-Ming Shih, Jim Jinn-Chyuan Sheu
Am J Pathol. 2011 May; 178(5): 2407–2415. doi: 10.1016/j.ajpath.2011.01.043
PMCID:
PMC3081206
Abstract Full Text PDF–1.6M Supplementary Material

Vascular Biology, Atherosclerosis, and Endothelium Biology

Interleukin-1β Inhibition Prevents Choroidal Neovascularization and Does Not Exacerbate Photoreceptor Degeneration
Sophie Lavalette, William Raoul, Marianne Houssier, Serge Camelo, Olivier Levy, Bertrand Calippe, Laurent Jonet, Francine Behar-Cohen, Sylvain Chemtob, Xavier Guillonneau, Christophe Combadière, Florian Sennlaub
Am J Pathol. 2011 May; 178(5): 2416–2423. doi: 10.1016/j.ajpath.2011.01.013
PMCID:
PMC3081145
Abstract Full Text PDF–1.6M
Ultrastructural Analysis Reveals cAMP-Dependent Enhancement of Microvascular Endothelial Barrier Functions via Rac1-Mediated Reorganization of Intercellular Junctions
Volker Spindler, Dominik Peter, Gregory S. Harms, Esther Asan, Jens Waschke
Am J Pathol. 2011 May; 178(5): 2424–2436. doi: 10.1016/j.ajpath.2011.01.014
PMCID:
PMC3081154
Abstract Full Text PDF–4.2M Supplementary Material
Physiological Contribution of CD44 as a Ligand for E-Selectin during Inflammatory T-Cell Recruitment
Maria Nácher, Ana Belén Blázquez, Bojing Shao, Adela Matesanz, Colette Prophete, M. Cecilia Berin, Paul S. Frenette, Andrés Hidalgo
Am J Pathol. 2011 May; 178(5): 2437–2446. doi: 10.1016/j.ajpath.2011.01.039
PMCID:
PMC3081198
Abstract Full Text PDF–1.4M Supplementary Material

Correspondence

The Beneficial Effects of Statin Therapy May Not Apply to All Forms of Crescentic Glomerulonephritis
Bahjat Al-Ani, Hamad Al Nuaimi, Caroline Savage, Mark A. Little, Akira Shimizu, Emiko Fujita, Shinya Nagasaka
Am J Pathol. 2011 May; 178(5): 2447–2448. doi: 10.1016/j.ajpath.2010.12.058
PMCID:
PMC3081163
Full Text PDF–83K
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