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Volume 163(2);  May 2011

Statistics Editorials

Statistics: all together now, one step at a time
Gordon B Drummond, David J Paterson, P McLoughlin, John C McGrath
Br J Pharmacol. 2011 May; 163(2): 207. doi: 10.1111/j.1476-5381.2011.01252.x
PMCID:
PMC3087124
Full Text PDF–72K
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GB Drummond, SL Vowler
Br J Pharmacol. 2011 May; 163(2): 208–210. doi: 10.1111/j.1476-5381.2011.01251.x
PMCID:
PMC3087125
Abstract Full Text PDF–294K Supplementary Material

Reviews

Alzheimer's disease & metals: therapeutic opportunities
Vijaya B Kenche, Kevin J Barnham
Br J Pharmacol. 2011 May; 163(2): 211–219. doi: 10.1111/j.1476-5381.2011.01221.x
PMCID:
PMC3087126
Abstract Full Text PDF–698K Supplementary Material
Role of the endothelin axis and its antagonists in the treatment of cancer
A Bagnato, M Loizidou, BR Pflug, J Curwen, J Growcott
Br J Pharmacol. 2011 May; 163(2): 220–233. doi: 10.1111/j.1476-5381.2011.01217.x
PMCID:
PMC3087127
Abstract Full Text PDF–768K Supplementary Material
Flavonoid modulation of GABAA receptors
Jane R Hanrahan, Mary Chebib, Graham A R Johnston
Br J Pharmacol. 2011 May; 163(2): 234–245. doi: 10.1111/j.1476-5381.2011.01228.x
PMCID:
PMC3087128
Abstract Full Text PDF–869K Supplementary Material
G protein-coupled receptors: walking hand-in-hand, talking hand-in-hand?
Henry F Vischer, Anne O Watts, Saskia Nijmeijer, Rob Leurs
Br J Pharmacol. 2011 May; 163(2): 246–260. doi: 10.1111/j.1476-5381.2011.01229.x
PMCID:
PMC3087129
Abstract Full Text PDF–1.8M Supplementary Material

Research Papers

Role of phosphodiesterase and adenylate cyclase isozymes in murine colonic glucagon-like peptide 1 secreting cells
Ronn S Friedlander, Catherine E Moss, Jessica Mace, Helen E Parker, Gwen Tolhurst, Abdella M Habib, Sebastian Wachten, Dermot M Cooper, Fiona M Gribble, Frank Reimann
Br J Pharmacol. 2011 May; 163(2): 261–271. doi: 10.1111/j.1476-5381.2010.01107.x
PMCID:
PMC3087130
Abstract Full Text PDF–1.2M Supplementary Material
Nicorandil ameliorates ischaemia-reperfusion injury in the rat kidney
Shogo Shimizu, Motoaki Saito, Yukako Kinoshita, Fumiya Ohmasa, Fotios Dimitriadis, Kohei Shomori, Atsushi Hayashi, Keisuke Satoh
Br J Pharmacol. 2011 May; 163(2): 272–282. doi: 10.1111/j.1476-5381.2011.01231.x
PMCID:
PMC3087131
Abstract Full Text PDF–2.0M Supplementary Material
γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent
Peramaiyan Rajendran, Feng Li, Kanjoormana Aryan Manu, Muthu K Shanmugam, Ser Yue Loo, Alan Prem Kumar, Gautam Sethi
Br J Pharmacol. 2011 May; 163(2): 283–298. doi: 10.1111/j.1476-5381.2010.01187.x
PMCID:
PMC3087132
Abstract Full Text PDF–1.8M Supplementary Material
Role of hypoxia-inducible factors in the dexrazoxane-mediated protection of cardiomyocytes from doxorubicin-induced toxicity
RD Spagnuolo, S Recalcati, L Tacchini, G Cairo
Br J Pharmacol. 2011 May; 163(2): 299–312. doi: 10.1111/j.1476-5381.2011.01208.x
PMCID:
PMC3087133
Abstract Full Text PDF–1.3M Supplementary Material
Stable expression and functional characterization of a human nicotinic acetylcholine receptor with α6β2 properties: discovery of selective antagonists
Anna Maria Capelli, Laura Castelletti, Yu Hua Chen, Harjeet Van der Keyl, Luca Pucci, Beatrice Oliosi, Cristian Salvagno, Barbara Bertani, Cecilia Gotti, Andrew Powell, Manolo Mugnaini
Br J Pharmacol. 2011 May; 163(2): 313–329. doi: 10.1111/j.1476-5381.2011.01213.x
PMCID:
PMC3087134
Abstract Full Text PDF–1.2M Supplementary Material
Capsaicin in the periaqueductal gray induces analgesia via metabotropic glutamate receptor-mediated endocannabinoid retrograde disinhibition
H-T Liao, H-J Lee, Y-C Ho, L-C Chiou
Br J Pharmacol. 2011 May; 163(2): 330–345. doi: 10.1111/j.1476-5381.2011.01214.x
PMCID:
PMC3087135
Abstract Full Text PDF–2.0M Supplementary Material
bPiDI: a novel selective α6β2* nicotinic receptor antagonist and preclinical candidate treatment for nicotine abuse
Thomas E Wooters, Andrew M Smith, Marharyta Pivavarchyk, Kiran B Siripurapu, J Michael McIntosh, Zhenfa Zhang, Peter A Crooks, Michael T Bardo, Linda P Dwoskin
Br J Pharmacol. 2011 May; 163(2): 346–357. doi: 10.1111/j.1476-5381.2011.01220.x
PMCID:
PMC3087136
Abstract Full Text PDF–1.1M Supplementary Material
Inhibitor of PI3Kγ ameliorates TNBS-induced colitis in mice by affecting the functional activity of CD4+CD25+FoxP3+ regulatory T cells
RC Dutra, M Cola, DFP Leite, AF Bento, RF Claudino, AFZ Nascimento, PC Leal, JB Calixto
Br J Pharmacol. 2011 May; 163(2): 358–374. doi: 10.1111/j.1476-5381.2011.01226.x
PMCID:
PMC3087137
Abstract Full Text PDF–3.6M Supplementary Material
Chronic treatment with a novel γ-secretase modulator, JNJ-40418677, inhibits amyloid plaque formation in a mouse model of Alzheimer's disease
B Van Broeck, J-M Chen, G Tréton, M Desmidt, C Hopf, N Ramsden, E Karran, M Mercken, A Rowley
Br J Pharmacol. 2011 May; 163(2): 375–389. doi: 10.1111/j.1476-5381.2011.01207.x
PMCID:
PMC3087138
Abstract Full Text PDF–1.0M Supplementary Material
Characterization of the mechanisms of the increase in PPARδ expression induced by digoxin in the heart using the H9c2 cell line
Zhih-Cherng Chen, Bu-Chin Yu, Li-Jen Chen, Kai-Chun Cheng, Hung Jung Lin, Juei-Tang Cheng
Br J Pharmacol. 2011 May; 163(2): 390–398. doi: 10.1111/j.1476-5381.2011.01212.x
PMCID:
PMC3087139
Abstract Full Text PDF–1.0M Supplementary Material
Site-specific PEGylation of exenatide analogues markedly improved their glucoregulatory activity
Nian Gong, Ai-Niu Ma, Li-Jie Zhang, Xiao-Su Luo, Yin-Hui Zhang, Michael Xu, Yong-Xiang Wang
Br J Pharmacol. 2011 May; 163(2): 399–412. doi: 10.1111/j.1476-5381.2011.01227.x
PMCID:
PMC3087140
Abstract Full Text PDF–1.7M Supplementary Material
Lymphocyte function antigen-1 regulates neutrophil recruitment and tissue damage in acute pancreatitis
Darbaz Awla, Aree Abdulla, Su Zhang, Jonas Roller, Michael D Menger, Sara Regnér, Henrik Thorlacius
Br J Pharmacol. 2011 May; 163(2): 413–423. doi: 10.1111/j.1476-5381.2011.01225.x
PMCID:
PMC3087141
Abstract Full Text PDF–1.3M Supplementary Material
Metformin restores endothelial function in aorta of diabetic rats
Cristina M Sena, Paulo Matafome, Teresa Louro, Elsa Nunes, Rosa Fernandes, Raquel M Seiça
Br J Pharmacol. 2011 May; 163(2): 424–437. doi: 10.1111/j.1476-5381.2011.01230.x
PMCID:
PMC3087142
Abstract Full Text PDF–2.1M Supplementary Material
Regulation of renal sympathetic neurotransmission by renal α2A-adrenoceptors is impaired in chronic renal failure
Henning Hoch, Johannes Stegbauer, Sebastian A Potthoff, Lutz Hein, Ivo Quack, Lars Christian Rump, Oliver Vonend
Br J Pharmacol. 2011 May; 163(2): 438–446. doi: 10.1111/j.1476-5381.2011.01223.x
PMCID:
PMC3087143
Abstract Full Text PDF–1.0M Supplementary Material
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