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Editorial Obituary: Hidesaburo Hanafusa 1929–2009 Stephan M Feller PMCID: PMC2673226 Research Expression of excess receptors and negative feedback control of signal pathways are required for rapid activation and prompt cessation of signal transduction Hiroshi Kobayashi, Ryuzo Azuma, and Takuo Yasunaga PMCID: PMC2666736 Early cellular signaling responses to axonal injury Thomas J Lukas, Ai Ling Wang, Ming Yuan, and Arthur H Neufeld PMCID: PMC2661080 Src, PKCα, and PKCδ are required for αvβ3 integrin-mediated metastatic melanoma invasion Andrew J Putnam, Veronique V Schulz, Eric M Freiter, Heather M Bill, and Cindy K Miranti PMCID: PMC2683837 Distinct phosphorylation requirements regulate cortactin activation by TirEPEC and its binding to N-WASP Elvira Nieto-Pelegrin and Narcisa Martinez-Quiles PMCID: PMC2686683 Rac1 activation inhibits E-cadherin-mediated adherens junctions via binding to IQGAP1 in pancreatic carcinoma cells Beatrix Hage, Katrin Meinel, Iris Baum, Klaudia Giehl, and Andre Menke PMCID: PMC2745413 Reviews Nck adapter proteins: functional versatility in T cells Marcus Lettau, Jennifer Pieper, and Ottmar Janssen PMCID: PMC2661883 Signal Transduction in the Footsteps of Goethe and Schiller Karlheinz Friedrich, Jonathan A Lindquist, Frank Entschladen, Edgar Serfling, Gerald Thiel, Arnd Kieser, Klaudia Giehl, Christina Ehrhardt, Stephan M Feller, Oliver Ullrich, Fred Schaper, Ottmar Janssen, and Ralf Hass PMCID: PMC2645404 Connexins: a myriad of functions extending beyond assembly of gap junction channels Hashem A Dbouk, Rana M Mroue, Marwan E El-Sabban, and Rabih S Talhouk PMCID: PMC2660342 Regulation of cellular proliferation, differentiation and cell death by activated Raf Gerald Thiel, Myriam Ekici, and Oliver G Rössler PMCID: PMC2676293 The roles of ASK family proteins in stress responses and diseases Kazuki Hattori, Isao Naguro, Christopher Runchel, and Hidenori Ichijo PMCID: PMC2685135 The receptor RAGE: Bridging inflammation and cancer Astrid Riehl, Julia Németh, Peter Angel, and Jochen Hess PMCID: PMC2690588 Crk and CrkL adaptor proteins: networks for physiological and pathological signaling Raymond B Birge, Charalampos Kalodimos, Fuyuhiko Inagaki, and Shinya Tanaka PMCID: PMC2689226 Expression and function of the insulin receptor substrate proteins in cancer Katerina Mardilovich, Shannon L Pankratz, and Leslie M Shaw PMCID: PMC2709114 Activin signaling as an emerging target for therapeutic interventions Kunihiro Tsuchida, Masashi Nakatani, Keisuke Hitachi, Akiyoshi Uezumi, Yoshihide Sunada, Hiroshi Ageta, and Kaoru Inokuchi PMCID: PMC2713245 Illuminating the life of GPCRs Ilka Böhme and Annette G Beck-Sickinger PMCID: PMC2726148 Tumor biology and cancer therapy – an evolving relationship Thomas Seufferlein, Johann Ahn, Denis Krndija, Ulrike Lother, Guido Adler, and Götz von Wichert PMCID: PMC2731766 Cholinergic receptor pathways involved in apoptosis, cell proliferation and neuronal differentiation Rodrigo R Resende and Avishek Adhikari PMCID: PMC2744676 Plasma membrane rafts engaged in T cell signalling: new developments in an old concept Thomas Harder and Dhaval Sangani PMCID: PMC2744677 Function, regulation and pathological roles of the Gab/DOS docking proteins Franziska U Wöhrle, Roger J Daly, and Tilman Brummer PMCID: PMC2747914 Eps15: a multifunctional adaptor protein regulating intracellular trafficking Paul MP van Bergen en Henegouwen PMCID: PMC2767346 Novel inhibitors of the calcineurin/NFATc hub - alternatives to CsA and FK506? Matthias Sieber and Ria Baumgrass PMCID: PMC2774854 Leptin and Adiponectin: new players in the field of tumor cell and leukocyte migration Kerstin Lang and Janina Ratke PMCID: PMC2804604 Short Reports Identification of subpopulations in mesenchymal stem cell-like cultures from human umbilical cord Ingrida Majore, Pierre Moretti, Ralf Hass, and Cornelia Kasper PMCID: PMC2676292 HSP90 is essential for Jak-STAT signaling in classical Hodgkin lymphoma cells Nils Schoof, Frederike von Bonin, Lorenz Trümper, and Dieter Kube PMCID: PMC2714310 Short report Differential requirement for MEK Partner 1 in DU145 prostate cancer cell migration Electa R Park, Ashok K Pullikuth, Evangeline M Bailey, Donald E Mercante, and Andrew D Catling PMCID: PMC2788567 Other Issues: Journal List
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