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Volume 10;  2012

Commentaries

Outbreaks of virulent diarrheagenic Escherichia coli - are we in control?
Dirk Werber, Gérard Krause, Christina Frank, Angelika Fruth, Antje Flieger, Martin Mielke, Lars Schaade, Klaus Stark
BMC Med. 2012; 10: 11. Published online 2012 February 2. doi: 10.1186/1741-7015-10-11
PMCID:
PMC3350439
Abstract Full Text PDF–290K
Treatment of enterohemorrhagic Escherichia coli (EHEC) infection and hemolytic uremic syndrome (HUS)
Paul N Goldwater, Karl A Bettelheim
BMC Med. 2012; 10: 12. Published online 2012 February 2. doi: 10.1186/1741-7015-10-12
PMCID:
PMC3286370
Abstract Full Text PDF–287K
Can racial disparities in optimal gout treatment be reduced? evidence from a randomized trial
Jasvinder A Singh
BMC Med. 2012; 10: 15. Published online 2012 February 9. doi: 10.1186/1741-7015-10-15
PMCID:
PMC3337326
Abstract Full Text PDF–210K
Is the efficacy of psychopharmacological drugs comparable to the efficacy of general medicine medication?
Florian Seemüller, Hans-Jürgen Möller, Sandra Dittmann, Richard Musil
BMC Med. 2012; 10: 17. Published online 2012 February 15. doi: 10.1186/1741-7015-10-17
PMCID:
PMC3308206
Abstract Full Text PDF–154K
Location, location, location: the BRMS1 protein and melanoma progression
Adam I Riker, Rajeev S Samant
BMC Med. 2012; 10: 19. Published online 2012 February 22. doi: 10.1186/PREACCEPT-2032291833666638
PMCID:
PMC3298489
Abstract Full Text PDF–380K
Transcriptome changes in age-related macular degeneration
S Scott Whitmore, Robert F Mullins
BMC Med. 2012; 10: 21. Published online 2012 February 27. doi: 10.1186/1741-7015-10-21
PMCID:
PMC3307472
Abstract Full Text PDF–316K
Sufficient blood, safe blood: can we have both?
Halvard Bönig, Michael Schmidt, Kai Hourfar, Jörg Schüttrumpf, Erhard Seifried
BMC Med. 2012; 10: 29. Published online 2012 March 23. doi: 10.1186/1741-7015-10-29
PMCID:
PMC3326707
Abstract Full Text PDF–211K
Crosstalk between HIV and hepatitis C virus during co-infection
Paul J Rider, Fenyong Liu
BMC Med. 2012; 10: 32. Published online 2012 April 3. doi: 10.1186/1741-7015-10-32
PMCID:
PMC3339559
Abstract Full Text PDF–202K
Evidence that an APOE ε4 'double whammy' increases risk for Alzheimer's disease
Ina Caesar, Sam Gandy
BMC Med. 2012; 10: 36. Published online 2012 April 13. doi: 10.1186/1741-7015-10-36
PMCID:
PMC3356233
Abstract Full Text PDF–1.2M
Differential susceptibility to plasticity: a 'missing link' between gene-culture co-evolution and neuropsychiatric spectrum disorders?
Rachel Wurzman, James Giordano
BMC Med. 2012; 10: 37. Published online 2012 April 17. doi: 10.1186/1741-7015-10-37
PMCID:
PMC3348034
Abstract Full Text PDF–171K

Debate

A public health approach to understanding and preventing violent radicalization
Kamaldeep S Bhui, Madelyn H Hicks, Myrna Lashley, Edgar Jones
BMC Med. 2012; 10: 16. Published online 2012 February 14. doi: 10.1186/1741-7015-10-16
PMCID:
PMC3305506
Abstract Full Text PDF–277K

Minireviews

Clinical application of stem cell therapy in Parkinson's disease
Marios Politis, Olle Lindvall
BMC Med. 2012; 10: 1. Published online 2012 January 4. doi: 10.1186/1741-7015-10-1
PMCID:
PMC3261810
Abstract Full Text PDF–993K
suPAR as a prognostic biomarker in sepsis
Katia Donadello, Sabino Scolletta, Cecilia Covajes, Jean-Louis Vincent
BMC Med. 2012; 10: 2. Published online 2012 January 5. doi: 10.1186/1741-7015-10-2
PMCID:
PMC3275545
Abstract Full Text PDF–636K
The role of copeptin as a diagnostic and prognostic biomarker for risk stratification in the emergency department
Christian H Nickel, Roland Bingisser, Nils G Morgenthaler
BMC Med. 2012; 10: 7. Published online 2012 January 20. doi: 10.1186/1741-7015-10-7
PMCID:
PMC3275505
Abstract Full Text PDF–329K
Is inhibition of kinase activity the only therapeutic strategy for LRRK2-associated Parkinson's disease?
Iakov N Rudenko, Ruth Chia, Mark R Cookson
BMC Med. 2012; 10: 20. Published online 2012 February 23. doi: 10.1186/1741-7015-10-20
PMCID:
PMC3308210
Abstract Full Text PDF–338K
Advances in using PARP inhibitors to treat cancer
Shivaani Kummar, Alice Chen, Ralph E Parchment, Robert J Kinders, Jay Ji, Joseph E Tomaszewski, James H Doroshow
BMC Med. 2012; 10: 25. Published online 2012 March 9. doi: 10.1186/1741-7015-10-25
PMCID:
PMC3312820
Abstract Full Text PDF–227K Supplementary Material

Opinion

Spectrum of gluten-related disorders: consensus on new nomenclature and classification
Anna Sapone, Julio C Bai, Carolina Ciacci, Jernej Dolinsek, Peter HR Green, Marios Hadjivassiliou, Katri Kaukinen, Kamran Rostami, David S Sanders, Michael Schumann, Reiner Ullrich, Danilo Villalta, Umberto Volta, Carlo Catassi, Alessio Fasano
BMC Med. 2012; 10: 13. Published online 2012 February 7. doi: 10.1186/1741-7015-10-13
PMCID:
PMC3292448
Abstract Full Text PDF–775K
Viral hemorrhagic fevers: advancing the level of treatment
Giuseppe Ippolito, Heinz Feldmann, Simone Lanini, Francesco Vairo, Antonino Di Caro, Maria Rosaria Capobianchi, Emanuele Nicastri
BMC Med. 2012; 10: 31. Published online 2012 March 29. doi: 10.1186/1741-7015-10-31
PMCID:
PMC3325866
Abstract Full Text PDF–268K

Research Articles

Reversal of type 1 diabetes via islet β cell regeneration following immune modulation by cord blood-derived multipotent stem cells
Yong Zhao, Zhaoshun Jiang, Tingbao Zhao, Mingliang Ye, Chengjin Hu, Zhaohui Yin, Heng Li, Ye Zhang, Yalin Diao, Yunxiang Li, Yingjian Chen, Xiaoming Sun, Mary Beth Fisk, Randal Skidgel, Mark Holterman, Bellur Prabhakar, Theodore Mazzone
BMC Med. 2012; 10: 3. Published online 2012 January 10. doi: 10.1186/1741-7015-10-3
PMCID:
PMC3322343
Abstract Full Text PDF–838K Supplementary Material
Systematic review and meta-analysis of the value of initial biomarkers in predicting adverse outcome in febrile neutropenic episodes in children and young people with cancer
Robert S Phillips, Ros Wade, Thomas Lehrnbecher, Lesley A Stewart, Alex J Sutton
BMC Med. 2012; 10: 6. Published online 2012 January 18. doi: 10.1186/1741-7015-10-6
PMCID:
PMC3331823
Abstract Full Text PDF–621K Supplementary Material
Clinical evaluation of iron treatment efficiency among non-anemic but iron-deficient female blood donors: a randomized controlled trial
Sophie Waldvogel, Baptiste Pedrazzini, Paul Vaucher, Raphael Bize, Jacques Cornuz, Jean-Daniel Tissot, Bernard Favrat
BMC Med. 2012; 10: 8. Published online 2012 January 24. doi: 10.1186/1741-7015-10-8
PMCID:
PMC3292842
Abstract Full Text PDF–518K
Diindolylmethane suppresses ovarian cancer growth and potentiates the effect of cisplatin in tumor mouse model by targeting signal transducer and activator of transcription 3 (STAT3)
Prabodh K Kandala, Sanjay K Srivastava
BMC Med. 2012; 10: 9. Published online 2012 January 26. doi: 10.1186/1741-7015-10-9
PMCID:
PMC3298725
Abstract Full Text PDF–1.2M
Zinc adjunct therapy reduces case fatality in severe childhood pneumonia: a randomized double blind placebo-controlled trial
Maheswari G Srinivasan, Grace Ndeezi, Cordelia Katureebe Mboijana, Sarah Kiguli, Gabriel S Bimenya, Victoria Nankabirwa, James K Tumwine
BMC Med. 2012; 10: 14. Published online 2012 February 8. doi: 10.1186/1741-7015-10-14
PMCID:
PMC3296597
Abstract Full Text PDF–306K
Rest versus exercise as treatment for patients with low back pain and Modic changes. a randomized controlled clinical trial
Rikke K Jensen, Charlotte Leboeuf-Yde, Niels Wedderkopp, Joan S Sorensen, Claus Manniche
BMC Med. 2012; 10: 22. Published online 2012 February 29. doi: 10.1186/1741-7015-10-22
PMCID:
PMC3348080
Abstract Full Text PDF–725K Supplementary Material
Fasudil improves survival and promotes skeletal muscle development in a mouse model of spinal muscular atrophy
Melissa Bowerman, Lyndsay M Murray, Justin G Boyer, Carrie L Anderson, Rashmi Kothary
BMC Med. 2012; 10: 24. Published online 2012 March 7. doi: 10.1186/1741-7015-10-24
PMCID:
PMC3310724
Abstract Full Text PDF–9.6M Supplementary Material
Insufficient maintenance DNA methylation is associated with abnormal embryonic development
Li-Jun Yin, Yu Zhang, Ping-Ping Lv, Wei-Hua He, Yan-Ting Wu, Ai-Xia Liu, Guo-Lian Ding, Min-Yue Dong, Fan Qu, Chen-Ming Xu, Xiao-Ming Zhu, He-Feng Huang
BMC Med. 2012; 10: 26. Published online 2012 March 13. doi: 10.1186/1741-7015-10-26
PMCID:
PMC3355050
Abstract Full Text PDF–2.0M
Targeting the epidermal growth factor receptor in non-small cell lung cancer cells: the effect of combining RNA interference with tyrosine kinase inhibitors or cetuximab
Gang Chen, Peter Kronenberger, Erik Teugels, Ijeoma Adaku Umelo, Jacques De Grève
BMC Med. 2012; 10: 28. Published online 2012 March 21. doi: 10.1186/1741-7015-10-28
PMCID:
PMC3334713
Abstract Full Text PDF–6.4M
Comparative effectiveness of antihypertensive medication for primary prevention of cardiovascular disease: systematic review and multiple treatments meta-analysis
Atle Fretheim, Jan Odgaard-Jensen, Odd Brørs, Steinar Madsen, Inger Njølstad, Ole F Norheim, Arne Svilaas, Ivar S Kristiansen, Hanne Thürmer, Signe Flottorp
BMC Med. 2012; 10: 33. Published online 2012 April 5. doi: 10.1186/1741-7015-10-33
PMCID:
PMC3354999
Abstract Full Text PDF–358K Supplementary Material
Apolipoprotein epsilon 3 alleles are associated with indicators of neuronal resilience
Orwa Aboud, Robert E Mrak, Frederick Boop, Sue T Griffin
BMC Med. 2012; 10: 35. Published online 2012 April 13. doi: 10.1186/1741-7015-10-35
PMCID:
PMC3352297
Abstract Full Text PDF–4.2M
Lifestyle factors affecting gastroesophageal reflux disease symptoms: a cross-sectional study of healthy 19864 adults using FSSG scores
Nobutake Yamamichi, Satoshi Mochizuki, Itsuko Asada-Hirayama, Rie Mikami-Matsuda, Takeshi Shimamoto, Maki Konno-Shimizu, Yu Takahashi, Chihiro Takeuchi, Keiko Niimi, Satoshi Ono, Shinya Kodashima, Chihiro Minatsuki, Mitsuhiro Fujishiro, Toru Mitsushima, Kazuhiko Koike
BMC Med. 2012; 10: 45. Published online 2012 May 3. doi: 10.1186/1741-7015-10-45
PMCID:
PMC3353848
Abstract Full Text PDF–372K Supplementary Material
Lifestyle interventions for overweight and obese pregnant women to improve pregnancy outcome: systematic review and meta-analysis
Eugene Oteng-Ntim, Rajesh Varma, Helen Croker, Lucilla Poston, Pat Doyle
BMC Med. 2012; 10: 47. Published online 2012 May 10. doi: 10.1186/1741-7015-10-47
PMCID:
PMC3355057
Abstract Full Text PDF–437K

Reviews

Frailty in primary care: a review of its conceptualization and implications for practice
Alethea Lacas, Kenneth Rockwood
BMC Med. 2012; 10: 4. Published online 2012 January 11. doi: 10.1186/1741-7015-10-4
PMCID:
PMC3271962
Abstract Full Text PDF–283K
Therapy for metastatic melanoma: the past, present, and future
Laura Finn, Svetomir N Markovic, Richard W Joseph
BMC Med. 2012; 10: 23. Published online 2012 March 2. doi: 10.1186/1741-7015-10-23
PMCID:
PMC3308914
Abstract Full Text PDF–821K
Viruses exacerbating chronic pulmonary disease: the role of immune modulation
Aran Singanayagam, Priya V Joshi, Patrick Mallia, Sebastian L Johnston
BMC Med. 2012; 10: 27. Published online 2012 March 15. doi: 10.1186/1741-7015-10-27
PMCID:
PMC3353868
Abstract Full Text PDF–528K
Novel therapeutic strategies targeting HIV integrase
Peter K Quashie, Richard D Sloan, Mark A Wainberg
BMC Med. 2012; 10: 34. Published online 2012 April 12. doi: 10.1186/1741-7015-10-34
PMCID:
PMC3348091
Abstract Full Text PDF–435K
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