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Volume 8;  2010
Commentaries
Basic and clinical significance of IGF-I-induced signatures in cancer
Haim Werner and Ilan Bruchim
BMC Med. 2010; 8: 2. Published online 2010 January 5. doi: 10.1186/1741-7015-8-2.
PMCID: PMC2806256
The interleukin-1 cluster, dyslipidaemia and risk of myocardial infarction
Bernard Keavney
BMC Med. 2010; 8: 6. Published online 2010 January 13. doi: 10.1186/1741-7015-8-6.
PMCID: PMC2822811
Transparent and accurate reporting increases reliability, utility, and impact of your research: reporting guidelines and the EQUATOR Network
Iveta Simera, David Moher, Allison Hirst, John Hoey, Kenneth F Schulz, and Douglas G Altman
BMC Med. 2010; 8: 24. Published online 2010 April 26. doi: 10.1186/1741-7015-8-24.
PMCID: PMC2874506
Hypoxia-specific targets in cancer therapy: role of splice variants
Dirk Vordermark
BMC Med. 2010; 8: 45. Published online 2010 July 12. doi: 10.1186/1741-7015-8-45.
PMCID: PMC2909930
Enhancement drugs: are there limits to what we should enhance and why?
Morten Hesse
BMC Med. 2010; 8: 50. Published online 2010 August 3. doi: 10.1186/1741-7015-8-50.
PMCID: PMC2922074
Correspondence
CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials
Kenneth F Schulz, Douglas G Altman, and David Moher
BMC Med. 2010; 8: 18. Published online 2010 March 24. doi: 10.1186/1741-7015-8-18.
PMCID: PMC2860339
What is a clinical pathway? Development of a definition to inform the debate
Leigh Kinsman, Thomas Rotter, Erica James, Pamela Snow, and Jon Willis
BMC Med. 2010; 8: 31. Published online 2010 May 27. doi: 10.1186/1741-7015-8-31.
PMCID: PMC2893088
Chronic fatigue syndrome: Harvey and Wessely's (bio)psychosocial model versus a bio(psychosocial) model based on inflammatory and oxidative and nitrosative stress pathways
Michael Maes and Frank NM Twisk
BMC Med. 2010; 8: 35. Published online 2010 June 15. doi: 10.1186/1741-7015-8-35.
PMCID: PMC2901228
Debates
Access to pain treatment as a human right
Diederik Lohman, Rebecca Schleifer, and Joseph J Amon
BMC Med. 2010; 8: 8. Published online 2010 January 20. doi: 10.1186/1741-7015-8-8.
PMCID: PMC2823656
Current sample size conventions: Flaws, harms, and alternatives
Peter Bacchetti
BMC Med. 2010; 8: 17. Published online 2010 March 22. doi: 10.1186/1741-7015-8-17.
PMCID: PMC2856520
Cardiovascular risk assessment - From individual risk prediction to estimation of global risk and change in risk in the population
John A Batsis and Francisco Lopez-Jimenez
BMC Med. 2010; 8: 29. Published online 2010 May 25. doi: 10.1186/1741-7015-8-29.
PMCID: PMC2890533
The impact of herpes zoster and post-herpetic neuralgia on quality-of-life
Robert W Johnson, Didier Bouhassira, George Kassianos, Alain Leplège, Kenneth E Schmader, and Thomas Weinke
BMC Med. 2010; 8: 37. Published online 2010 June 21. doi: 10.1186/1741-7015-8-37.
PMCID: PMC2905321
Minireview
Recent advances in radiotherapy
SA Bhide and CM Nutting
BMC Med. 2010; 8: 25. Published online 2010 April 28. doi: 10.1186/1741-7015-8-25.
PMCID: PMC2873246
Research Articles
Brief psychological therapies for anxiety and depression in primary care: meta-analysis and meta-regression
John Cape, Craig Whittington, Marta Buszewicz, Paul Wallace, and Lisa Underwood
BMC Med. 2010; 8: 38. Published online 2010 June 25. doi: 10.1186/1741-7015-8-38.
PMCID: PMC2908553
Does chocolate reduce blood pressure? A meta-analysis
Karin Ried, Thomas Sullivan, Peter Fakler, Oliver R Frank, and Nigel P Stocks
BMC Med. 2010; 8: 39. Published online 2010 June 28. doi: 10.1186/1741-7015-8-39.
PMCID: PMC2908554
Reduced acquisition and reactivation of human papillomavirus infections among older women treated with cryotherapy: results from a randomized trial in South Africa
Sylvia Taylor, Chunhui Wang, Thomas C Wright, Lynette Denny, Wei-Yann Tsai, and Louise Kuhn
BMC Med. 2010; 8: 40. Published online 2010 June 29. doi: 10.1186/1741-7015-8-40.
PMCID: PMC2907297
Neonatal hypothermia and associated risk factors among newborns of southern Nepal
Luke C Mullany, Joanne Katz, Subarna K Khatry, Steven C LeClerq, Gary L Darmstadt, and James M Tielsch
BMC Med. 2010; 8: 43. Published online 2010 July 8. doi: 10.1186/1741-7015-8-43.
PMCID: PMC2911389
Hypoxia inducible factor 1α gene (HIF-1α) splice variants: potential prognostic biomarkers in breast cancer
Jean-Philippe Dales, Nathalie Beaufils, Monique Silvy, Christophe Picard, Vanessa Pauly, Vincent Pradel, Christine Formisano-Tréziny, Pascal Bonnier, Sophie Giusiano, Colette Charpin, and Jean Gabert
BMC Med. 2010; 8: 44. Published online 2010 July 12. doi: 10.1186/1741-7015-8-44.
PMCID: PMC2917392
Targeted exercise against osteoporosis: A systematic review and meta-analysis for optimising bone strength throughout life
Riku Nikander, Harri Sievänen, Ari Heinonen, Robin M Daly, Kirsti Uusi-Rasi, and Pekka Kannus
BMC Med. 2010; 8: 47. Published online 2010 July 21. doi: 10.1186/1741-7015-8-47.
PMCID: PMC2918523
Relationship between knee and ankle degeneration in a population of organ donors
Carol Muehleman, Arkady Margulis, Won C Bae, and Koichi Masuda
BMC Med. 2010; 8: 48. Published online 2010 July 28. doi: 10.1186/1741-7015-8-48.
PMCID: PMC2925325
Research articles
IGF-I induced genes in stromal fibroblasts predict the clinical outcome of breast and lung cancer patients
Michal Rajski, Rosanna Zanetti-Dällenbach, Brigitte Vogel, Richard Herrmann, Christoph Rochlitz, and Martin Buess
BMC Med. 2010; 8: 1. Published online 2010 January 5. doi: 10.1186/1741-7015-8-1.
PMCID: PMC2823652
A randomized phase II study of carboplatin plus pegylated liposomal doxorubicin versus carboplatin plus paclitaxel in platinum sensitive ovarian cancer patients: a Hellenic Cooperative Oncology Group study
Dimitrios Bafaloukos, Helena Linardou, Gerasimos Aravantinos, Christos Papadimitriou, Aristotelis Bamias, George Fountzilas, Haralabos P Kalofonos, Paris Kosmidis, Eleni Timotheadou, Thomas Makatsoris, Epaminondas Samantas, Evangelos Briasoulis, Christos Christodoulou, Pavlos Papakostas, Dimitrios Pectasides, and Athanasios M Dimopoulos
BMC Med. 2010; 8: 3. Published online 2010 January 7. doi: 10.1186/1741-7015-8-3.
PMCID: PMC2823653
Suicide-related behaviors in older patients with new anti-epileptic drug use: data from the VA hospital system
Anne C VanCott, Joyce A Cramer, Laurel A Copeland, John E Zeber, Michael A Steinman, Jeffrey J Dersh, Mark E Glickman, Eric M Mortensen, Megan E Amuan, and Mary Jo Pugh
BMC Med. 2010; 8: 4. Published online 2010 January 11. doi: 10.1186/1741-7015-8-4.
PMCID: PMC2823654
An evaluation of inflammatory gene polymorphisms in sibships discordant for premature coronary artery disease: the GRACE-IMMUNE study
Benjamin D Brown, Jérémie Nsengimana, Jennifer H Barrett, Richard A Lawrence, Lori Steiner, Suzanne Cheng, D Timothy Bishop, Nilesh J Samani, Stephen G Ball, Anthony J Balmforth, and Alistair S Hall
BMC Med. 2010; 8: 5. Published online 2010 January 13. doi: 10.1186/1741-7015-8-5.
PMCID: PMC2823655
An in-depth assessment of a diagnosis-based risk adjustment model based on national health insurance claims: the application of the Johns Hopkins Adjusted Clinical Group case-mix system in Taiwan
Hsien-Yen Chang and Jonathan P Weiner
BMC Med. 2010; 8: 7. Published online 2010 January 18. doi: 10.1186/1741-7015-8-7.
PMCID: PMC2830174
Ruling out coronary heart disease in primary care patients with chest pain: a clinical prediction score
Baris Gencer, Paul Vaucher, Lilli Herzig, François Verdon, Christiane Ruffieux, Stefan Bösner, Bernard Burnand, Thomas Bischoff, Norbert Donner-Banzhoff, and Bernard Favrat
BMC Med. 2010; 8: 9. Published online 2010 January 21. doi: 10.1186/1741-7015-8-9.
PMCID: PMC2832616
The effectiveness of the McKenzie method in addition to first-line care for acute low back pain: a randomized controlled trial
Luciana AC Machado, Chris G Maher, Rob D Herbert, Helen Clare, and James H McAuley
BMC Med. 2010; 8: 10. Published online 2010 January 26. doi: 10.1186/1741-7015-8-10.
PMCID: PMC2842230
Incidence, detection, and tumour stage of breast cancer in a cohort of Italian women with negative screening mammography report recommending early (short-interval) rescreen
Alessandra Ravaioli, Flavia Foca, Americo Colamartini, Fabio Falcini, Carlo Naldoni, Alba C Finarelli, Priscilla Sassoli de Bianchi, and Lauro Bucchi
BMC Med. 2010; 8: 11. Published online 2010 February 1. doi: 10.1186/1741-7015-8-11.
PMCID: PMC2829482
A functional polymorphism in the DNA methyltransferase-3A promoter modifies the susceptibility in gastric cancer but not in esophageal carcinoma
Hong Fan, Dongsheng Liu, Xuemei Qiu, Fengchang Qiao, Qingxiang Wu, Xianwei Su, Feng Zhang, Yunwei Song, Zhujiang Zhao, and Wei Xie
BMC Med. 2010; 8: 12. Published online 2010 February 3. doi: 10.1186/1741-7015-8-12.
PMCID: PMC2829483
Reduced levels of hydroxylated, polyunsaturated ultra long-chain fatty acids in the serum of colorectal cancer patients: implications for early screening and detection
Shawn A Ritchie, Pearson WK Ahiahonu, Dushmanthi Jayasinghe, Doug Heath, Jun Liu, Yingshen Lu, Wei Jin, Amir Kavianpour, Yasuyo Yamazaki, Amin M Khan, Mohammad Hossain, Khine Khine Su-Myat, Paul L Wood, Kevin Krenitsky, Ichiro Takemasa, Masakazu Miyake, Mitsugu Sekimoto, Morito Monden, Hisahiro Matsubara, Fumio Nomura, and Dayan B Goodenowe
BMC Med. 2010; 8: 13. Published online 2010 February 15. doi: 10.1186/1741-7015-8-13.
PMCID: PMC2833138
Mitf-Mdel, a novel melanocyte/melanoma-specific isoform of microphthalmia-associated transcription factor-M, as a candidate biomarker for melanoma
Yixiang Wang, Soroosh Radfar, Suhu Liu, Adam I Riker, and Hung T Khong
BMC Med. 2010; 8: 14. Published online 2010 February 17. doi: 10.1186/1741-7015-8-14.
PMCID: PMC2839965
Frequency and circumstances of placebo use in clinical practice - a systematic review of empirical studies
Margrit Fässler, Karin Meissner, Antonius Schneider, and Klaus Linde
BMC Med. 2010; 8: 15. Published online 2010 February 23. doi: 10.1186/1741-7015-8-15.
PMCID: PMC2837612
Neonatal seizures in a rural Kenyan District Hospital: aetiology, Incidence and outcome of hospitalization
Michael Mwaniki, Ali Mathenge, Samson Gwer, Neema Mturi, Evasius Bauni, Charles RJC Newton, James Berkley, and Richard Idro
BMC Med. 2010; 8: 16. Published online 2010 March 17. doi: 10.1186/1741-7015-8-16.
PMCID: PMC2846860
The cytoprotective drug amifostine modifies both expression and activity of the pro-angiogenic factor VEGF-A
S Dedieu, X Canron, HR Rezvani, M Bouchecareilh, F Mazurier, R Sinisi, M Zanda, M Moenner, A Bikfalvi, and S North
BMC Med. 2010; 8: 19. Published online 2010 March 24. doi: 10.1186/1741-7015-8-19.
PMCID: PMC2859403
Reporting methods in studies developing prognostic models in cancer: a review
Susan Mallett, Patrick Royston, Susan Dutton, Rachel Waters, and Douglas G Altman
BMC Med. 2010; 8: 20. Published online 2010 March 30. doi: 10.1186/1741-7015-8-20.
PMCID: PMC2856521
Reporting performance of prognostic models in cancer: a review
Susan Mallett, Patrick Royston, Rachel Waters, Susan Dutton, and Douglas G Altman
BMC Med. 2010; 8: 21. Published online 2010 March 30. doi: 10.1186/1741-7015-8-21.
PMCID: PMC2857810
Does targeting manual therapy and/or exercise improve patient outcomes in nonspecific low back pain? A systematic review
Peter Kent, Hanne L Mjøsund, and Ditte HD Petersen
BMC Med. 2010; 8: 22. Published online 2010 April 8. doi: 10.1186/1741-7015-8-22.
PMCID: PMC2873245
Temporal trends in hospitalisation for stroke recurrence following incident hospitalisation for stroke in Scotland
James Lewsey, Pardeep S Jhund, Michelle Gillies, Jim WT Chalmers, Adam Redpath, Andrew Briggs, Matthew Walters, Peter Langhorne, Simon Capewell, John JV McMurray, and Kate MacIntyre
BMC Med. 2010; 8: 23. Published online 2010 April 9. doi: 10.1186/1741-7015-8-23.
PMCID: PMC2859404
Chromosome copy number changes carry prognostic information independent of KIT/PDGFRA point mutations in gastrointestinal stromal tumors
Mara Silva, Isabel Veiga, Franclim R Ribeiro, Joana Vieira, Carla Pinto, Manuela Pinheiro, Bárbara Mesquita, Catarina Santos, Marta Soares, José Dinis, Lúcio Santos, Paula Lopes, Mariana Afonso, Carlos Lopes, and Manuel R Teixeira
BMC Med. 2010; 8: 26. Published online 2010 May 14. doi: 10.1186/1741-7015-8-26.
PMCID: PMC2876987
The normal breast microenvironment of premenopausal women differentially influences the behavior of breast cancer cells in vitro and in vivo
Jodie M Fleming, Tyler C Miller, Mariam Quinones, Zhen Xiao, Xia Xu, Matthew J Meyer, Erika Ginsburg, Timothy D Veenstra, and Barbara K Vonderhaar
BMC Med. 2010; 8: 27. Published online 2010 May 21. doi: 10.1186/1741-7015-8-27.
PMCID: PMC2894739
BODE-Index vs HADO-Score in Chronic Obstructive Pulmonary Disease: Which one to use in general practice?
Cristóbal Esteban, José M Quintana, Javier Moraza, Myriam Aburto, Urko Aguirre, José I Aguirregomoscorta, Susana Aizpiri, Luis V Basualdo, and Alberto Capelastegui
BMC Med. 2010; 8: 28. Published online 2010 May 24. doi: 10.1186/1741-7015-8-28.
PMCID: PMC2880999
Symptomatic treatment (ibuprofen) or antibiotics (ciprofloxacin) for uncomplicated urinary tract infection? - Results of a randomized controlled pilot trial
Jutta Bleidorn, Ildikó Gágyor, Michael M Kochen, Karl Wegscheider, and Eva Hummers-Pradier
BMC Med. 2010; 8: 30. Published online 2010 May 26. doi: 10.1186/1741-7015-8-30.
PMCID: PMC2890534
Physical activity and depressive symptoms in adolescents: a prospective study
Catherine Rothon, Phil Edwards, Kamaldeep Bhui, Russell M Viner, Stephanie Taylor, and Stephen A Stansfeld
BMC Med. 2010; 8: 32. Published online 2010 May 28. doi: 10.1186/1741-7015-8-32.
PMCID: PMC2895574
US public opinion regarding proposed limits on resident physician work hours
Alexander B Blum, Farbod Raiszadeh, Sandra Shea, David Mermin, Peter Lurie, Christopher P Landrigan, and Charles A Czeisler
BMC Med. 2010; 8: 33. Published online 2010 June 1. doi: 10.1186/1741-7015-8-33.
PMCID: PMC2901227
Triple antiplatelet therapy for preventing vascular events: a systematic review and meta-analysis
Chamila Geeganage, Robert Wilcox, and Philip MW Bath
BMC Med. 2010; 8: 36. Published online 2010 June 16. doi: 10.1186/1741-7015-8-36.
PMCID: PMC2893089
Reviews
Biomarkers in acute myocardial infarction
Daniel Chan and Leong L Ng
BMC Med. 2010; 8: 34. Published online 2010 June 7. doi: 10.1186/1741-7015-8-34.
PMCID: PMC2898678
Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan
H Teede, A Deeks, and L Moran
BMC Med. 2010; 8: 41. Published online 2010 June 30. doi: 10.1186/1741-7015-8-41.
PMCID: PMC2909929
Zinc Finger Nucleases as tools to understand and treat human diseases
David Davis and David Stokoe
BMC Med. 2010; 8: 42. Published online 2010 July 1. doi: 10.1186/1741-7015-8-42.
PMCID: PMC2904710
Managing hyperemesis gravidarum: a multimodal challenge
JK Jueckstock, R Kaestner, and I Mylonas
BMC Med. 2010; 8: 46. Published online 2010 July 15. doi: 10.1186/1741-7015-8-46.
PMCID: PMC2913953
Correction
Development of lower limb range of motion from early childhood to adolescence in cerebral palsy: a population-based study
Eva Nordmark, Gunnar Hägglund, Henrik Lauge-Pedersen, Philippe Wagner, and Lena Westbom
BMC Med. 2010; 8: 49. Published online 2010 July 28. doi: 10.1186/1741-7015-8-49.
PMCID: PMC2917393
Corrects: Eva Nordmark, et al. Development of lower limb range of motion from early childhood to adolescence in cerebral palsy: a population-based study. BMC Med. 2009; 7: 65.
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