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Volume 106(46);  November 17, 2009
Letters
Parameters that influence the prediction of epidemiological benefits of more-effective tuberculosis vaccines, drugs, and diagnosis
Janakiraman Vani, Mohan S. Maddur, Sébastien Lacroix-Desmazes, Srini V. Kaveri, and Jagadeesh Bayry
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): E129. Published online 2009 October 26. doi: 10.1073/pnas.0911020106.
PMCID: PMC2780754
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Reply to Vani et al.: Tuberculosis models and complexity
M. Elizabeth Halloran, Jerusha T. Achterberg, Lorenzo Sabatelli, Jonathan D. Sugimoto, Christopher Dye, and Ira M. Longini, Jr.
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): E130. Published online 2009 October 26. doi: 10.1073/pnas.0911578106.
PMCID: PMC2780744
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This Week in PNAS
In This Issue
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19205–19206. doi: 10.1073/iti4609106.
PMCID: PMC2780788
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Commentaries
How to learn new and interesting things from model systems based on “exotic” biological species
John M. Sedivy
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19207–19208. Published online 2009 November 11. doi: 10.1073/pnas.0911232106.
PMCID: PMC2780764
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Enter the ratrix
Bijan Pesaran and David Kleinfeld
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19209–19210. Published online 2009 November 11. doi: 10.1073/pnas.0911424106.
PMCID: PMC2780815
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Perspective
Climate, carbon cycling, and deep-ocean ecosystems
K. L. Smith, Jr, H. A. Ruhl, B. J. Bett, D. S. M. Billett, R. S. Lampitt, and R. S. Kaufmann
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19211–19218. Published online 2009 November 9. doi: 10.1073/pnas.0908322106.
PMCID: PMC2780780
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Physical Sciences
Applied Physical Sciences
Propulsion of African trypanosomes is driven by bihelical waves with alternating chirality separated by kinks
Jose A. Rodríguez, Miguel A. Lopez, Michelle C. Thayer, Yunzhe Zhao, Michael Oberholzer, Donald D. Chang, Neville K. Kisalu, Manuel L. Penichet, Gustavo Helguera, Robijn Bruinsma, Kent L. Hill, and Jianwei Miao
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19322–19327. Published online 2009 October 30. doi: 10.1073/pnas.0907001106.
PMCID: PMC2780783
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Engineering
Ultra-sensitive vibrational spectroscopy of protein monolayers with plasmonic nanoantenna arrays
Ronen Adato, Ahmet A. Yanik, Jason J. Amsden, David L. Kaplan, Fiorenzo G. Omenetto, Mi K. Hong, Shyamsunder Erramilli, and Hatice Altug
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19227–19232. Published online 2009 October 30. doi: 10.1073/pnas.0907459106.
PMCID: PMC2770897
Environmental Sciences
Sodium shortage as a constraint on the carbon cycle in an inland tropical rainforest
Michael Kaspari, Stephen P. Yanoviak, Robert Dudley, May Yuan, and Natalie A. Clay
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19405–19409. Published online 2009 November 2. doi: 10.1073/pnas.0906448106.
PMCID: PMC2780770
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Geophysics
High-pressure highly reduced nitrides and oxides from chromitite of a Tibetan ophiolite
Larissa F. Dobrzhinetskaya, Richard Wirth, Jingsui Yang, Ian D. Hutcheon, Peter K. Weber, and Harry W. Green, II
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19233–19238. Published online 2009 October 30. doi: 10.1073/pnas.0905514106.
PMCID: PMC2780801
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Physics
Emergent gene order in a model of modular polyketide synthases
Benjamin Callahan, Mukund Thattai, and Boris I. Shraiman
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19410–19415. Published online 2009 October 28. doi: 10.1073/pnas.0902364106.
PMCID: PMC2780807
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Statistics
Direct observation of twisting steps during Rad51 polymerization on DNA
Hideyuki Arata, Aurélie Dupont, Judith Miné-Hattab, Ludovic Disseau, Axelle Renodon-Cornière, Masayuki Takahashi, Jean-Louis Viovy, and Giovanni Cappello
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19239–19244. Published online 2009 November 2. doi: 10.1073/pnas.0902234106.
PMCID: PMC2780809
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Biological Sciences
Agricultural Sciences
A nonsense mutation in cGMP-dependent type II protein kinase (PRKG2) causes dwarfism in American Angus cattle
James E. Koltes, Bishnu P. Mishra, Dinesh Kumar, Ranjit S. Kataria, Liviu R. Totir, Rohan L. Fernando, Rowland Cobbold, David Steffen, Wouter Coppieters, Michel Georges, and James M. Reecy
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19250–19255. Published online 2009 November 3. doi: 10.1073/pnas.0904513106.
PMCID: PMC2780805
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A dominant, coordinated T regulatory cell-IgA response to the intestinal microbiota
Yingzi Cong, Ting Feng, Kohtaro Fujihashi, Trenton R. Schoeb, and Charles O. Elson
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19256–19261. Published online 2009 November 4. doi: 10.1073/pnas.0812681106.
PMCID: PMC2780781
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Anthropology
Contagious yawning in gelada baboons as a possible expression of empathy
E. Palagi, A. Leone, G. Mancini, and P. F. Ferrari
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19262–19267. Published online 2009 November 4. doi: 10.1073/pnas.0910891106.
PMCID: PMC2780782
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Applied Biological Sciences
From the Cover:
Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier
Benjamin C. Tang, Michelle Dawson, Samuel K. Lai, Ying-Ying Wang, Jung Soo Suk, Ming Yang, Pamela Zeitlin, Michael P. Boyle, Jie Fu, and Justin Hanes
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19268–19273. Published online 2009 November 9. doi: 10.1073/pnas.0905998106.
PMCID: PMC2780804
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Biochemistry
Crystal structures of the noncatalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor
Masashi Akiyama, Soichi Takeda, Koichi Kokame, Junichi Takagi, and Toshiyuki Miyata
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19274–19279. Published online 2009 October 30. doi: 10.1073/pnas.0909755106.
PMCID: PMC2780749
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Relapsing fever Borrelia binds to neolacto glycans and mediates rosetting of human erythrocytes
Betty P. Guo, Susann Teneberg, Robert Münch, Daiyo Terunuma, Ken Hatano, Koji Matsuoka, Jonas Ångström, Thomas Borén, and Sven Bergström
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19280–19285. Published online 2009 November 2. doi: 10.1073/pnas.0905470106.
PMCID: PMC2771742
Dynamic bookmarking of primary response genes by p300 and RNA polymerase II complexes
Jung S. Byun, Madeline M. Wong, Wenwu Cui, Gila Idelman, Quentin Li, Adriana De Siervi, Sven Bilke, Cynthia M. Haggerty, Audrey Player, Yong Hong Wang, Michael J. Thirman, Joseph J. Kaberlein, Constantinos Petrovas, Richard A. Koup, Dan Longo, Keiko Ozato, and Kevin Gardner
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19286–19291. Published online 2009 October 30. doi: 10.1073/pnas.0905469106.
PMCID: PMC2780808
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Structure of Escherichia coli Hfq bound to polyriboadenylate RNA
Todd M. Link, Poul Valentin-Hansen, and Richard G. Brennan
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19292–19297. Published online 2009 November 4. doi: 10.1073/pnas.0908744106.
PMCID: PMC2773200
Telomere capping proteins are structurally related to RPA with an additional telomere-specific domain
Amy D. Gelinas, Margherita Paschini, Francis E. Reyes, Annie Héroux, Robert T. Batey, Victoria Lundblad, and Deborah S. Wuttke
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19298–19303. Published online 2009 November 2. doi: 10.1073/pnas.0909203106.
PMCID: PMC2780795
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Functional genomic screens identify CINP as a genome maintenance protein
Courtney A. Lovejoy, Xin Xu, Carol E. Bansbach, Gloria G. Glick, Runxiang Zhao, Fei Ye, Bianca M. Sirbu, Laura C. Titus, Yu Shyr, and David Cortez
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19304–19309. Published online 2009 November 4. doi: 10.1073/pnas.0909345106.
PMCID: PMC2780779
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Global profiling of protease cleavage sites by chemoselective labeling of protein N-termini
Guoqiang Xu, Sung Bin Y. Shin, and Samie R. Jaffrey
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19310–19315. Published online 2009 November 5. doi: 10.1073/pnas.0908958106.
PMCID: PMC2780798
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Cyclodextrin overcomes deficient lysosome-to-endoplasmic reticulum transport of cholesterol in Niemann-Pick type C cells
Lina Abi-Mosleh, Rodney E. Infante, Arun Radhakrishnan, Joseph L. Goldstein, and Michael S. Brown
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19316–19321. Published online 2009 November 2. doi: 10.1073/pnas.0910916106.
PMCID: PMC2780767
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Biophysics and Computational Biology
Ultra-sensitive vibrational spectroscopy of protein monolayers with plasmonic nanoantenna arrays
Ronen Adato, Ahmet A. Yanik, Jason J. Amsden, David L. Kaplan, Fiorenzo G. Omenetto, Mi K. Hong, Shyamsunder Erramilli, and Hatice Altug
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19227–19232. Published online 2009 October 30. doi: 10.1073/pnas.0907459106.
PMCID: PMC2770897
Direct observation of twisting steps during Rad51 polymerization on DNA
Hideyuki Arata, Aurélie Dupont, Judith Miné-Hattab, Ludovic Disseau, Axelle Renodon-Cornière, Masayuki Takahashi, Jean-Louis Viovy, and Giovanni Cappello
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19239–19244. Published online 2009 November 2. doi: 10.1073/pnas.0902234106.
PMCID: PMC2780809
| Free in PMC on 2010/05/17 |
Propulsion of African trypanosomes is driven by bihelical waves with alternating chirality separated by kinks
Jose A. Rodríguez, Miguel A. Lopez, Michelle C. Thayer, Yunzhe Zhao, Michael Oberholzer, Donald D. Chang, Neville K. Kisalu, Manuel L. Penichet, Gustavo Helguera, Robijn Bruinsma, Kent L. Hill, and Jianwei Miao
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19322–19327. Published online 2009 October 30. doi: 10.1073/pnas.0907001106.
PMCID: PMC2780783
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Kinetic enhancement of NF-κB·DNA dissociation by IκBα
Simon Bergqvist, Vera Alverdi, Benedicte Mengel, Alexander Hoffmann, Gourisankar Ghosh, and Elizabeth A. Komives
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19328–19333. Published online 2009 November 3. doi: 10.1073/pnas.0908797106.
PMCID: PMC2780789
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The physical state of water in bacterial spores
Erik P. Sunde, Peter Setlow, Lars Hederstedt, and Bertil Halle
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19334–19339. Published online 2009 November 5. doi: 10.1073/pnas.0908712106.
PMCID: PMC2780810
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Single-molecule denaturation and degradation of proteins by the AAA+ ClpXP protease
Yongdae Shin, Joseph H. Davis, Ricardo R. Brau, Andreas Martin, Jon A. Kenniston, Tania A. Baker, Robert T. Sauer, and Matthew J. Lang
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19340–19345. Published online 2009 November 5. doi: 10.1073/pnas.0910484106.
PMCID: PMC2773733
Conformational selection and induced fit mechanism underlie specificity in noncovalent interactions with ubiquitin
Tomasz Wlodarski and Bojan Zagrovic
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19346–19351. Published online 2009 November 3. doi: 10.1073/pnas.0906966106.
PMCID: PMC2780739
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Cell Biology
From the Cover:
Hypersensitivity to contact inhibition provides a clue to cancer resistance of naked mole-rat
Andrei Seluanov, Christopher Hine, Jorge Azpurua, Marina Feigenson, Michael Bozzella, Zhiyong Mao, Kenneth C. Catania, and Vera Gorbunova
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19352–19357. Published online 2009 October 26. doi: 10.1073/pnas.0905252106.
PMCID: PMC2780760
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From the Cover:
STIM1-induced precortical and cortical subdomains of the endoplasmic reticulum
Lelio Orci, Mariella Ravazzola, Marion Le Coadic, Wei-wei Shen, Nicolas Demaurex, and Pierre Cosson
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19358–19362. Published online 2009 November 11. doi: 10.1073/pnas.0911280106.
PMCID: PMC2775999
G9a selectively represses a class of late-replicating genes at the nuclear periphery
Tomoki Yokochi, Kristina Poduch, Tyrone Ryba, Junjie Lu, Ichiro Hiratani, Makoto Tachibana, Yoichi Shinkai, and David M. Gilbert
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19363–19368. Published online 2009 November 4. doi: 10.1073/pnas.0906142106.
PMCID: PMC2780741
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Movement and equipositioning of plasmids by ParA filament disassembly
Simon Ringgaard, Jeroen van Zon, Martin Howard, and Kenn Gerdes
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19369–19374. Published online 2009 November 11. doi: 10.1073/pnas.0908347106.
PMCID: PMC2775997
Soft X-ray tomography of phenotypic switching and the cellular response to antifungal peptoids in Candida albicans
Maho Uchida, Gerry McDermott, Modi Wetzler, Mark A. Le Gros, Markko Myllys, Christian Knoechel, Annelise E. Barron, and Carolyn A. Larabell
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19375–19380. Published online 2009 October 30. doi: 10.1073/pnas.0906145106.
PMCID: PMC2780763
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Tug-of-war between dissimilar teams of microtubule motors regulates transport and fission of endosomes
Virupakshi Soppina, Arpan Kumar Rai, Avin Jayesh Ramaiya, Pradeep Barak, and Roop Mallik
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19381–19386. Published online 2009 October 28. doi: 10.1073/pnas.0906524106.
PMCID: PMC2770008
Oscillatory recruitment of signaling proteins to cell tips promotes coordinated behavior during cell fusion
André Fleissner, Abigail C. Leeder, M. Gabriela Roca, Nick D. Read, and N. Louise Glass
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19387–19392. Published online 2009 November 2. doi: 10.1073/pnas.0907039106.
PMCID: PMC2780775
| Free in PMC on 2010/05/17 |
Telomere shortening relaxes X chromosome inactivation and forces global transcriptome alterations
Stefan Schoeftner, Raquel Blanco, Isabel Lopez de Silanes, Purificación Muñoz, Gonzalo Gómez-López, Juana M. Flores, and Maria A. Blasco
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19393–19398. Published online 2009 November 3. doi: 10.1073/pnas.0909265106.
PMCID: PMC2772818
Developmental Biology
The receptor protein tyrosine phosphatase LAR promotes R7 photoreceptor axon targeting by a phosphatase-independent signaling mechanism
Kerstin Hofmeyer and Jessica E. Treisman
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19399–19404. Published online 2009 November 4. doi: 10.1073/pnas.0903961106.
PMCID: PMC2780745
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Ecology
Sodium shortage as a constraint on the carbon cycle in an inland tropical rainforest
Michael Kaspari, Stephen P. Yanoviak, Robert Dudley, May Yuan, and Natalie A. Clay
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19405–19409. Published online 2009 November 2. doi: 10.1073/pnas.0906448106.
PMCID: PMC2780770
| Free in PMC on 2010/05/17 |
Evolution
Emergent gene order in a model of modular polyketide synthases
Benjamin Callahan, Mukund Thattai, and Boris I. Shraiman
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19410–19415. Published online 2009 October 28. doi: 10.1073/pnas.0902364106.
PMCID: PMC2780807
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How blood-derived odor influences mate-choice decisions by a mosquito-eating predator
Fiona R. Cross, Robert R. Jackson, and Simon D. Pollard
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19416–19419. Published online 2009 November 3. doi: 10.1073/pnas.0904125106.
PMCID: PMC2780784
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A mechanism for functional segregation of mitochondrial and cytosolic genetic codes
Yaiza Español, Daniel Thut, André Schneider, and Lluís Ribas de Pouplana
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19420–19425. Published online 2009 October 30. doi: 10.1073/pnas.0909937106.
PMCID: PMC2780774
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Ecologically dependent postmating isolation between sympatric host forms of Neochlamisus bebbianae leaf beetles
Scott P. Egan and Daniel J. Funk
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19426–19431. Published online 2009 October 29. doi: 10.1073/pnas.0909424106.
PMCID: PMC2780776
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Genetics
From the Cover:
Age-related hearing loss in C57BL/6J mice is mediated by Bak-dependent mitochondrial apoptosis
Shinichi Someya, Jinze Xu, Kenji Kondo, Dalian Ding, Richard J. Salvi, Tatsuya Yamasoba, Peter S. Rabinovitch, Richard Weindruch, Christiaan Leeuwenburgh, Masaru Tanokura, and Tomas A. Prolla
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19432–19437. Published online 2009 November 9. doi: 10.1073/pnas.0908786106.
PMCID: PMC2780799
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Loss of parity between IL-2 and IL-21 in the NOD Idd3 locus
Helen M. McGuire, Alexis Vogelzang, Natasha Hill, Malin Flodström-Tullberg, Jonathan Sprent, and Cecile King
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19438–19443. Published online 2009 October 30. doi: 10.1073/pnas.0903561106.
PMCID: PMC2780811
| Free in PMC on 2010/05/17 |
Rescue and characterization of episomally replicating DNA from the moss Physcomitrella
Eva Murén, Anders Nilsson, Mikael Ulfstedt, Monika Johansson, and Hans Ronne
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19444–19449. Published online 2009 November 5. doi: 10.1073/pnas.0908037106.
PMCID: PMC2780769
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Immunology
Adenovirus E3 MHC inhibitory genes but not TNF/Fas apoptotic inhibitory genes expressed in β cells prevent autoimmune diabetes
Marshall S. Horwitz, Shimon Efrat, Urs Christen, Matthias G. von Herrath, and Michael B. A. Oldstone
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19450–19454. Published online 2009 November 3. doi: 10.1073/pnas.0910648106.
PMCID: PMC2780797
| Free in PMC on 2010/05/17 |
Successful immunotherapy with IL-2/anti-CD40 induces the chemokine-mediated mitigation of an immunosuppressive tumor microenvironment
Jonathan M. Weiss, Timothy C. Back, Anthony J. Scarzello, Jeff J. Subleski, Veronica L. Hall, Jimmy K. Stauffer, Xin Chen, Dejan Micic, Kory Alderson, William J. Murphy, and Robert H. Wiltrout
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19455–19460. Published online 2009 November 5. doi: 10.1073/pnas.0909474106.
PMCID: PMC2773732
Transcriptional regulator Id2 controls survival of hepatic NKT cells
Laurel A. Monticelli, Yang Yang, Jamie Knell, Louise M. D'Cruz, Michael A. Cannarile, Isaac Engel, Mitchell Kronenberg, and Ananda W. Goldrath
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19461–19466. Published online 2009 November 2. doi: 10.1073/pnas.0908249106.
PMCID: PMC2780802
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Medical Sciences
Prevention and treatment of cervical cancer in mice using estrogen receptor antagonists
Sang-Hyuk Chung and Paul F. Lambert
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19467–19472. Published online 2009 November 9. doi: 10.1073/pnas.0911436106.
PMCID: PMC2780740
| Free in PMC on 2010/05/17 |
A t-butyloxycarbonyl-modified Wnt5a-derived hexapeptide functions as a potent antagonist of Wnt5a-dependent melanoma cell invasion
Veronika Jenei, Victoria Sherwood, Jillian Howlin, Rickard Linnskog, Annette Säfholm, Lena Axelsson, and Tommy Andersson
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19473–19478. Published online 2009 November 9. doi: 10.1073/pnas.0909409106.
PMCID: PMC2780806
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PTEN dosage is essential for neurofibroma development and malignant transformation
Caroline Gregorian, Jonathan Nakashima, Sarah M. Dry, P. Leia Nghiemphu, Kate Barzan Smith, Yan Ao, Julie Dang, Gregory Lawson, Ingo K. Mellinghoff, Paul S. Mischel, Michael Phelps, Luis F. Parada, Xin Liu, Michael V. Sofroniew, Fritz C. Eilber, and Hong Wu
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19479–19484. Published online 2009 October 21. doi: 10.1073/pnas.0910398106.
PMCID: PMC2765459
Hypoxia-induced pathological angiogenesis mediates tumor cell dissemination, invasion, and metastasis in a zebrafish tumor model
Samantha Lin Chiou Lee, Pegah Rouhi, Lasse Dahl Jensen, Danfang Zhang, Hong Ji, Giselbert Hauptmann, Philip Ingham, and Yihai Cao
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19485–19490. Published online 2009 November 3. doi: 10.1073/pnas.0909228106.
PMCID: PMC2780785
| Free in PMC on 2010/05/17 |
Alpha 1,3 fucosyltransferases are master regulators of prostate cancer cell trafficking
Steven R. Barthel, Georg K. Wiese, Jaehyung Cho, Matthew J. Opperman, Danielle L. Hays, Javed Siddiqui, Kenneth J. Pienta, Bruce Furie, and Charles J. Dimitroff
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19491–19496. Published online 2009 November 4. doi: 10.1073/pnas.0906074106.
PMCID: PMC2780742
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Alternatively spliced tissue factor induces angiogenesis through integrin ligation
Y. W. van den Berg, L. G. van den Hengel, H. R. Myers, O. Ayachi, E. Jordanova, W. Ruf, C. A. Spek, P. H. Reitsma, V. Y. Bogdanov, and H. H. Versteeg
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19497–19502. Published online 2009 October 29. doi: 10.1073/pnas.0905325106.
PMCID: PMC2780792
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Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition
Anthony C. Faber, Danan Li, YoungChul Song, Mei-Chih Liang, Beow Y. Yeap, Roderick T. Bronson, Eugene Lifshits, Zhao Chen, Sauveur-Michel Maira, Carlos García-Echeverría, Kwok-Kin Wong, and Jeffrey A. Engelman
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19503–19508. Published online 2009 October 22. doi: 10.1073/pnas.0905056106.
PMCID: PMC2765921
Microbiology
Hydrodynamic gene delivery of baboon trypanosome lytic factor eliminates both animal and human-infective African trypanosomes
Russell Thomson, Pilar Molina-Portela, Helen Mott, Mark Carrington, and Jayne Raper
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19509–19514. Published online 2009 October 26. doi: 10.1073/pnas.0905669106.
PMCID: PMC2780755
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Cellular stress created by intermediary metabolite imbalances
Sang Jun Lee, Andrei Trostel, Phuoc Le, Rajendran Harinarayanan, Peter C. FitzGerald, and Sankar Adhya
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19515–19520. Published online 2009 November 3. doi: 10.1073/pnas.0910586106.
PMCID: PMC2780772
| Free in PMC on 2010/05/17 |
Nitrogen recycling and nutritional provisioning by Blattabacterium, the cockroach endosymbiont
Zakee L. Sabree, Srinivas Kambhampati, and Nancy A. Moran
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19521–19526. Published online 2009 October 30. doi: 10.1073/pnas.0907504106.
PMCID: PMC2780778
| Free in PMC on 2010/05/17 |
Cell cycle deregulation by a poxvirus partial mimic of anaphase-promoting complex subunit 11
Min Mo, Stephen B. Fleming, and Andrew A. Mercer
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19527–19532. Published online 2009 November 3. doi: 10.1073/pnas.0905893106.
PMCID: PMC2780751
| Free in PMC on 2010/05/17 |
A key role for vesicles in fungal secondary metabolism
Anindya Chanda, Ludmila V. Roze, Suil Kang, Katherine A. Artymovich, Glenn R. Hicks, Natasha V. Raikhel, Ana M. Calvo, and John E. Linz
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19533–19538. Published online 2009 November 4. doi: 10.1073/pnas.0907416106.
PMCID: PMC2773199
HIV-1 Vif-mediated ubiquitination/degradation of APOBEC3G involves four critical lysine residues in its C-terminal domain
Yasumasa Iwatani, Denise S. B. Chan, Lin Liu, Hiroaki Yoshii, Junko Shibata, Naoki Yamamoto, Judith G. Levin, Angela M. Gronenborn, and Wataru Sugiura
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19539–19544. Published online 2009 November 3. doi: 10.1073/pnas.0906652106.
PMCID: PMC2772817
Recent human-to-poultry host jump, adaptation, and pandemic spread of Staphylococcus aureus
Bethan V. Lowder, Caitriona M. Guinane, Nouri L. Ben Zakour, Lucy A. Weinert, Andrew Conway-Morris, Robyn A. Cartwright, A. John Simpson, Andrew Rambaut, Ulrich Nübel, and J. Ross Fitzgerald
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19545–19550. Published online 2009 November 2. doi: 10.1073/pnas.0909285106.
PMCID: PMC2780746
| Free in PMC on 2010/05/17 |
Neuroscience
Neural correlates of behavior in the moth Manduca sexta in response to complex odors
Jeffrey A. Riffell, H. Lei, and John G. Hildebrand
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19219–19226. Published online 2009 November 11. doi: 10.1073/pnas.0910592106.
PMCID: PMC2780752
| Free in PMC on 2010/05/17 |
Evolution amplified processing with temporally dispersed slow neuronal connectivity in primates
Roberto Caminiti, Hassan Ghaziri, Ralf Galuske, Patrick R. Hof, and Giorgio M. Innocenti
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19551–19556. Published online 2009 October 29. doi: 10.1073/pnas.0907655106.
PMCID: PMC2770441
From the Cover:
Visually evoked activity in cortical cells imaged in freely moving animals
Juergen Sawinski, Damian J. Wallace, David S. Greenberg, Silvie Grossmann, Winfried Denk, and Jason N. D. Kerr
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19557–19562. Published online 2009 November 4. doi: 10.1073/pnas.0903680106.
PMCID: PMC2773198
Stability of muscle synergies for voluntary actions after cortical stroke in humans
Vincent C. K. Cheung, Lamberto Piron, Michela Agostini, Stefano Silvoni, Andrea Turolla, and Emilio Bizzi
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19563–19568. Published online 2009 October 30. doi: 10.1073/pnas.0910114106.
PMCID: PMC2780765
| Free in PMC on 2010/05/17 |
Shape-specific preparatory activity mediates attention to targets in human visual cortex
Mark Stokes, Russell Thompson, Anna C. Nobre, and John Duncan
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19569–19574. Published online 2009 November 3. doi: 10.1073/pnas.0905306106.
PMCID: PMC2772815
Rapid modulation of spine morphology by the 5-HT2A serotonin receptor through kalirin-7 signaling
Kelly A. Jones, Deepak P. Srivastava, John A. Allen, Ryan T. Strachan, Bryan L. Roth, and Peter Penzes
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19575–19580. Published online 2009 November 4. doi: 10.1073/pnas.0905884106.
PMCID: PMC2780750
| Free in PMC on 2010/05/17 |
A homologous genetic basis of the murine cpfl1 mutant and human achromatopsia linked to mutations in the PDE6C gene
Bo Chang, Tanja Grau, Susann Dangel, Ron Hurd, Bernhard Jurklies, E. Cumhur Sener, Sten Andreasson, Helene Dollfus, Britta Baumann, Sylvia Bolz, Nikolai Artemyev, Susanne Kohl, John Heckenlively, and Bernd Wissinger
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19581–19586. Published online 2009 November 3. doi: 10.1073/pnas.0907720106.
PMCID: PMC2780790
| Free in PMC on 2010/05/17 |
Oncomodulin links inflammation to optic nerve regeneration
Yuqin Yin, Qi Cui, Hui-ya Gilbert, Yang Yang, Zhiyong Yang, Cynthia Berlinicke, Zhiwei Li, Camila Zaverucha-do-Valle, Huamei He, Victoria Petkova, Donald J. Zack, and Larry I. Benowitz
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19587–19592. Published online 2009 October 29. doi: 10.1073/pnas.0907085106.
PMCID: PMC2780793
| Free in PMC on 2010/05/17 |
Role of dysbindin in dopamine receptor trafficking and cortical GABA function
Yuanyuan Ji, Feng Yang, Francesco Papaleo, Huai-Xing Wang, Wen-Jun Gao, Daniel R. Weinberger, and Bai Lu
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19593–19598. Published online 2009 November 3. doi: 10.1073/pnas.0904289106.
PMCID: PMC2780743
| Free in PMC on 2010/05/17 |
HDAC6 is a target for protection and regeneration following injury in the nervous system
Mark A. Rivieccio, Camille Brochier, Dianna E. Willis, Breset A. Walker, Melissa A. D'Annibale, Kathryn McLaughlin, Ambreena Siddiq, Alan P. Kozikowski, Samie R. Jaffrey, Jeffery L. Twiss, Rajiv R. Ratan, and Brett Langley
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19599–19604. Published online 2009 November 2. doi: 10.1073/pnas.0907935106.
PMCID: PMC2780768
| Free in PMC on 2010/05/17 |
Synaptic scaffolding protein SYD-2 clusters and activates kinesin-3 UNC-104 in C. elegans
Oliver I. Wagner, Alessandro Esposito, Barbara Köhler, Chih-Wei Chen, Che-Piao Shen, Gong-Her Wu, Eugenia Butkevich, Sailaja Mandalapu, Dirk Wenzel, Fred S. Wouters, and Dieter R. Klopfenstein
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19605–19610. Published online 2009 October 30. doi: 10.1073/pnas.0902949106.
PMCID: PMC2780759
| Free in PMC on 2010/05/17 |
Pharmacology
Sulindac confers high level ischemic protection to the heart through late preconditioning mechanisms
Ian Moench, Howard Prentice, Zach Rickaway, and Herbert Weissbach
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19611–19616. Published online 2009 November 2. doi: 10.1073/pnas.0911046106.
PMCID: PMC2780796
| Free in PMC on 2010/05/17 |
Physiology
Deletion of Drosophila insulin-like peptides causes growth defects and metabolic abnormalities
Hua Zhang, Jingnan Liu, Caroline R. Li, Bahram Momen, Ronald A. Kohanski, and Leslie Pick
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19617–19622. Published online 2009 November 3. doi: 10.1073/pnas.0905083106.
PMCID: PMC2780814
| Free in PMC on 2010/05/17 |
Plasticity in Ca2+ selectivity of Orai1/Orai3 heteromeric channel
Rainer Schindl, Irene Frischauf, Judith Bergsmann, Martin Muik, Isabella Derler, Barbara Lackner, Klaus Groschner, and Christoph Romanin
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19623–19628. Published online 2009 November 3. doi: 10.1073/pnas.0907714106.
PMCID: PMC2780800
| Free in PMC on 2010/05/17 |
Social Sciences
Anthropology
Daily life of the ancient Maya recorded on murals at Calakmul, Mexico
Ramón Carrasco Vargas, Verónica A. Vázquez López, and Simon Martin
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19245–19249. Published online 2009 November 9. doi: 10.1073/pnas.0904374106.
PMCID: PMC2780771
| Free in PMC on 2010/05/17 |
Corrections
Correction for Lee et al., A robust method for searching the smallest set of smallest rings with a path-included distance matrix
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19629. Published online 2009 October 30. doi: 10.1073/pnas.0911801106.
PMCID: PMC2780757
Corrects: Chang Joon Lee, et al. A robust method for searching the smallest set of smallest rings with a path-included distance matrix. Proc Natl Acad Sci U S A. 2009 October 13; 106(41): 17355–17358.
Correction for Yoon et al., CIB1 functions as a Ca2+-sensitive modulator of stress-induced signaling by targeting ASK1
Proc Natl Acad Sci U S A. 2009 November 17; 106(46): 19629. Published online 2009 October 30. doi: 10.1073/pnas.0911831106.
PMCID: PMC2780758
Corrects: Kyoung Wan Yoon, et al. CIB1 functions as a Ca2+-sensitive modulator of stress-induced signaling by targeting ASK1. Proc Natl Acad Sci U S A. 2009 October 13; 106(41): 17389–17394.
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