• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of pnasPNASInfo for AuthorsEditorial BoardAboutSubscriptions

Volume 111(34);  August 26, 2014

Articles from this journal are usually available in PMC after a 6-month delay (embargo). Some articles may be available sooner.

This Week in PNAS

In This Issue
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12271–12272. Published online Aug 26, 2014. doi: 10.1073/iti3414111
PMCID:
PMC4151731

Letters

Female hurricanes are not deadlier than male hurricanes
Daniel Malter
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): E3496. Published online Aug 4, 2014. doi: 10.1073/pnas.1411428111
PMCID:
PMC4151744
Are female hurricanes really deadlier than male hurricanes?
Björn Christensen, Sören Christensen
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): E3497–E3498. Published online Aug 4, 2014. doi: 10.1073/pnas.1410910111
PMCID:
PMC4151713
Reply to Christensen and Christensen and to Malter: Pitfalls of erroneous analyses of hurricanes names
Kiju Jung, Sharon Shavitt, Madhu Viswanathan, Joseph M. Hilbe
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): E3499–E3500. Published online Aug 4, 2014. doi: 10.1073/pnas.1411652111
PMCID:
PMC4151722

Inner Workings

Rino Rappuoli
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12273. Published online Aug 26, 2014. doi: 10.1073/pnas.1414226111
PMCID:
PMC4151773

Commentaries

Pharmacological chaperones in the age of proteomic pathology
Scott A. Small
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12274–12275. Published online Aug 13, 2014. doi: 10.1073/pnas.1413111111
PMCID:
PMC4151756
Clovis at the end of the world
David J. Meltzer
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12276–12277. Published online Aug 13, 2014. doi: 10.1073/pnas.1412945111
PMCID:
PMC4151755
Fungal polyketide engineering comes of age
Vinayak Agarwal, Bradley S. Moore
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12278–12279. Published online Aug 12, 2014. doi: 10.1073/pnas.1412946111
PMCID:
PMC4151771

PNAS Plus Significance Statements

PNAS Plus Significance Statements
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12280–12281. Published online Aug 26, 2014. doi: 10.1073/pnas.ss11134
PMCID:
PMC4151729

PNAS Plus

Zhengyu Liu, Jiang Zhu, Yair Rosenthal, Xu Zhang, Bette L. Otto-Bliesner, Axel Timmermann, Robin S. Smith, Gerrit Lohmann, Weipeng Zheng, Oliver Elison Timm
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): E3501–E3505. Published online Aug 11, 2014. doi: 10.1073/pnas.1407229111
PMCID:
PMC4151775
A sequence-specific transcription activator motif and powerful synthetic variants that bind Mediator using a fuzzy protein interface
Linda Warfield, Lisa M. Tuttle, Derek Pacheco, Rachel E. Klevit, Steven Hahn
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): E3506–E3513. Published online Aug 13, 2014. doi: 10.1073/pnas.1412088111
PMCID:
PMC4151740
Structural basis for the recruitment and activation of the Legionella phospholipase VipD by the host GTPase Rab5
María Lucas, Andrew H. Gaspar, Chiara Pallara, Adriana Lucely Rojas, Juan Fernández-Recio, Matthias P. Machner, Aitor Hierro
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): E3514–E3523. Published online Aug 11, 2014. doi: 10.1073/pnas.1405391111
PMCID:
PMC4151760
Luca Turin, Efthimios M. C. Skoulakis, Andrew P. Horsfield
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): E3524–E3533. Published online Aug 11, 2014. doi: 10.1073/pnas.1404387111
PMCID:
PMC4151765
Distinct isoform of FABP7 revealed by screening for retroelement-activated genes in diffuse large B-cell lymphoma
Frances E. Lock, Rita Rebollo, Katharine Miceli-Royer, Liane Gagnier, Sabrina Kuah, Artem Babaian, Maialen Sistiaga-Poveda, C. Benjamin Lai, Oksana Nemirovsky, Isabel Serrano, Christian Steidl, Mohammad M. Karimi, Dixie L. Mager
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): E3534–E3543. Published online Aug 11, 2014. doi: 10.1073/pnas.1405507111
PMCID:
PMC4151764
Calcineurin determines toxic versus beneficial responses to α-synuclein
Gabriela Caraveo, Pavan K. Auluck, Luke Whitesell, Chee Yeun Chung, Valeriya Baru, Eugene V. Mosharov, Xiaohui Yan, Manu Ben-Johny, Martin Soste, Paola Picotti, Hanna Kim, Kim A. Caldwell, Guy A. Caldwell, David Sulzer, David T. Yue, Susan Lindquist
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): E3544–E3552. Published online Aug 13, 2014. doi: 10.1073/pnas.1413201111
PMCID:
PMC4151770
Small RNA combination therapy for lung cancer
Wen Xue, James E. Dahlman, Tuomas Tammela, Omar F. Khan, Sabina Sood, Apeksha Dave, Wenxin Cai, Leilani M. Chirino, Gillian R. Yang, Roderick Bronson, Denise G. Crowley, Gaurav Sahay, Avi Schroeder, Robert Langer, Daniel G. Anderson, Tyler Jacks
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): E3553–E3561. Published online Aug 11, 2014. doi: 10.1073/pnas.1412686111
PMCID:
PMC4151750
Margarida Rei, Natacha Gonçalves-Sousa, Telma Lança, Richard G. Thompson, Sofia Mensurado, Frances R. Balkwill, Hagen Kulbe, Daniel J. Pennington, Bruno Silva-Santos
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): E3562–E3570. Published online Aug 11, 2014. doi: 10.1073/pnas.1403424111
PMCID:
PMC4151711
Kai Graeber, Ada Linkies, Tina Steinbrecher, Klaus Mummenhoff, Danuše Tarkowská, Veronika Turečková, Michael Ignatz, Katja Sperber, Antje Voegele, Hans de Jong, Terezie Urbanová, Miroslav Strnad, Gerhard Leubner-Metzger
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): E3571–E3580. Published online Aug 11, 2014. doi: 10.1073/pnas.1403851111
PMCID:
PMC4151772

Introduction

Rino Rappuoli
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12282. Published online Aug 19, 2014. doi: 10.1073/pnas.1413559111
PMCID:
PMC4151739

Vaccines PNAS 100th Anniversary Special Feature

Rino Rappuoli
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12282. Published online Aug 19, 2014. doi: 10.1073/pnas.1413559111
PMCID:
PMC4151739
Stanley Plotkin
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12283–12287. Published online Aug 18, 2014. doi: 10.1073/pnas.1400472111
PMCID:
PMC4151719
Rino Rappuoli, Mariagrazia Pizza, Giuseppe Del Giudice, Ennio De Gregorio
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12288–12293. Published online Aug 18, 2014. doi: 10.1073/pnas.1402981111
PMCID:
PMC4151714
Charles Maisonneuve, Sylvie Bertholet, Dana J. Philpott, Ennio De Gregorio
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12294–12299. Published online Aug 18, 2014. doi: 10.1073/pnas.1400478111
PMCID:
PMC4151741
Bali Pulendran
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12300–12306. Published online Aug 18, 2014. doi: 10.1073/pnas.1400476111
PMCID:
PMC4151766
Calman A. MacLennan, Allan Saul
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12307–12312. Published online Aug 18, 2014. doi: 10.1073/pnas.1400473111
PMCID:
PMC4151718
Till Bärnighausen, David E. Bloom, Elizabeth T. Cafiero-Fonseca, Jennifer Carroll O’Brien
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12313–12319. Published online Aug 18, 2014. doi: 10.1073/pnas.1400475111
PMCID:
PMC4151736

Perspective

Stanley Plotkin
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12283–12287. Published online Aug 18, 2014. doi: 10.1073/pnas.1400472111
PMCID:
PMC4151719
Rino Rappuoli, Mariagrazia Pizza, Giuseppe Del Giudice, Ennio De Gregorio
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12288–12293. Published online Aug 18, 2014. doi: 10.1073/pnas.1402981111
PMCID:
PMC4151714
Charles Maisonneuve, Sylvie Bertholet, Dana J. Philpott, Ennio De Gregorio
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12294–12299. Published online Aug 18, 2014. doi: 10.1073/pnas.1400478111
PMCID:
PMC4151741
Bali Pulendran
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12300–12306. Published online Aug 18, 2014. doi: 10.1073/pnas.1400476111
PMCID:
PMC4151766
Calman A. MacLennan, Allan Saul
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12307–12312. Published online Aug 18, 2014. doi: 10.1073/pnas.1400473111
PMCID:
PMC4151718
Till Bärnighausen, David E. Bloom, Elizabeth T. Cafiero-Fonseca, Jennifer Carroll O’Brien
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12313–12319. Published online Aug 18, 2014. doi: 10.1073/pnas.1400475111
PMCID:
PMC4151736

Physical Sciences

Applied Physical Sciences

Brett H. Hokr, Joel N. Bixler, Gary D. Noojin, Robert J. Thomas, Benjamin A. Rockwell, Vladislav V. Yakovlev, Marlan O. Scully
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12320–12324. Published online Aug 11, 2014. doi: 10.1073/pnas.1412535111
PMCID:
PMC4151747
Collective credit allocation in science
Hua-Wei Shen, Albert-László Barabási
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12325–12330. Published online Aug 11, 2014. doi: 10.1073/pnas.1401992111
PMCID:
PMC4151753
A cellular solution to an information-processing problem
Garud Iyengar, Madan Rao
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12402–12407. Published online Aug 11, 2014. doi: 10.1073/pnas.1406608111
PMCID:
PMC4151762

Earth, Atmospheric, and Planetary Sciences

Clovis at the end of the world
David J. Meltzer
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12276–12277. Published online Aug 13, 2014. doi: 10.1073/pnas.1412945111
PMCID:
PMC4151755
Dim Coumou, Vladimir Petoukhov, Stefan Rahmstorf, Stefan Petri, Hans Joachim Schellnhuber
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12331–12336. Published online Aug 11, 2014. doi: 10.1073/pnas.1412797111
PMCID:
PMC4151761

Environmental Sciences

Zhengyu Liu, Jiang Zhu, Yair Rosenthal, Xu Zhang, Bette L. Otto-Bliesner, Axel Timmermann, Robin S. Smith, Gerrit Lohmann, Weipeng Zheng, Oliver Elison Timm
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): E3501–E3505. Published online Aug 11, 2014. doi: 10.1073/pnas.1407229111
PMCID:
PMC4151775

Physics

Fair sampling perspective on an apparent violation of duality
Eliot Bolduc, Jonathan Leach, Filippo M. Miatto, Gerd Leuchs, Robert W. Boyd
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12337–12341. Published online Aug 11, 2014. doi: 10.1073/pnas.1400106111
PMCID:
PMC4151752
Coevolutionary information, protein folding landscapes, and the thermodynamics of natural selection
Faruck Morcos, Nicholas P. Schafer, Ryan R. Cheng, José N. Onuchic, Peter G. Wolynes
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12408–12413. Published online Aug 11, 2014. doi: 10.1073/pnas.1413575111
PMCID:
PMC4151759

Social Sciences

Anthropology

Clovis at the end of the world
David J. Meltzer
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12276–12277. Published online Aug 13, 2014. doi: 10.1073/pnas.1412945111
PMCID:
PMC4151755
Simone Riehl, Konstantin E. Pustovoytov, Heike Weippert, Stefan Klett, Frank Hole
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12348–12353. Published online Aug 11, 2014. doi: 10.1073/pnas.1409516111
PMCID:
PMC4151733

Economic Sciences

Till Bärnighausen, David E. Bloom, Elizabeth T. Cafiero-Fonseca, Jennifer Carroll O’Brien
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12313–12319. Published online Aug 18, 2014. doi: 10.1073/pnas.1400475111
PMCID:
PMC4151736

Psychological and Cognitive Sciences

Female hurricanes are not deadlier than male hurricanes
Daniel Malter
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): E3496. Published online Aug 4, 2014. doi: 10.1073/pnas.1411428111
PMCID:
PMC4151744
Are female hurricanes really deadlier than male hurricanes?
Björn Christensen, Sören Christensen
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): E3497–E3498. Published online Aug 4, 2014. doi: 10.1073/pnas.1410910111
PMCID:
PMC4151713
Reply to Christensen and Christensen and to Malter: Pitfalls of erroneous analyses of hurricanes names
Kiju Jung, Sharon Shavitt, Madhu Viswanathan, Joseph M. Hilbe
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): E3499–E3500. Published online Aug 4, 2014. doi: 10.1073/pnas.1411652111
PMCID:
PMC4151722

Sustainability Science

Global agriculture and carbon trade-offs
Justin Andrew Johnson, Carlisle Ford Runge, Benjamin Senauer, Jonathan Foley, Stephen Polasky
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12342–12347. Published online Aug 11, 2014. doi: 10.1073/pnas.1412835111
PMCID:
PMC4151777

Biological Sciences

Anthropology

Simone Riehl, Konstantin E. Pustovoytov, Heike Weippert, Stefan Klett, Frank Hole
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12348–12353. Published online Aug 11, 2014. doi: 10.1073/pnas.1409516111
PMCID:
PMC4151733

Applied Biological Sciences

Pharmacological chaperones in the age of proteomic pathology
Scott A. Small
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12274–12275. Published online Aug 13, 2014. doi: 10.1073/pnas.1413111111
PMCID:
PMC4151756
Fungal polyketide engineering comes of age
Vinayak Agarwal, Bradley S. Moore
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12278–12279. Published online Aug 12, 2014. doi: 10.1073/pnas.1412946111
PMCID:
PMC4151771
Diversity-oriented combinatorial biosynthesis of benzenediol lactone scaffolds by subunit shuffling of fungal polyketide synthases
Yuquan Xu, Tong Zhou, Shuwei Zhang, Patricia Espinosa-Artiles, Luoyi Wang, Wei Zhang, Min Lin, A. A. Leslie Gunatilaka, Jixun Zhan, István Molnár
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12354–12359. Published online Jul 21, 2014. doi: 10.1073/pnas.1406999111
PMCID:
PMC4151742
Charles H. Jones, Anitha Ravikrishnan, Mingfu Chen, Ryan Reddinger, Mahmoud Kamal Ahmadi, Snehal Rane, Anders P. Hakansson, Blaine A. Pfeifer
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12360–12365. Published online Aug 11, 2014. doi: 10.1073/pnas.1411355111
PMCID:
PMC4151754

Biochemistry

Mapping the λ Integrase bridges in the nucleoprotein Holliday junction intermediates of viral integrative and excisive recombination
Wenjun Tong, David Warren, Nicole E. Seah, Gurunathan Laxmikanthan, Gregory D. Van Duyne, Arthur Landy
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12366–12371. Published online Aug 11, 2014. doi: 10.1073/pnas.1413007111
PMCID:
PMC4151763
Nicole E. Seah, David Warren, Wenjun Tong, Gurunathan Laxmikanthan, Gregory D. Van Duyne, Arthur Landy
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12372–12377. Published online Aug 11, 2014. doi: 10.1073/pnas.1413019111
PMCID:
PMC4151757
EFA6 controls Arf1 and Arf6 activation through a negative feedback loop
Dominique Padovani, Marcia Folly-Klan, Audrey Labarde, Sonia Boulakirba, Valérie Campanacci, Michel Franco, Mahel Zeghouf, Jacqueline Cherfils
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12378–12383. Published online Aug 11, 2014. doi: 10.1073/pnas.1409832111
PMCID:
PMC4151748
α-Fluorophosphonates reveal how a phosphomutase conserves transition state conformation over hexose recognition in its two-step reaction
Yi Jin, Debabrata Bhattasali, Erika Pellegrini, Stephanie M. Forget, Nicola J. Baxter, Matthew J. Cliff, Matthew W. Bowler, David L. Jakeman, G. Michael Blackburn, Jonathan P. Waltho
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12384–12389. Published online Aug 7, 2014. doi: 10.1073/pnas.1402850111
PMCID:
PMC4151737
Jonathan E. Bird, Yasuharu Takagi, Neil Billington, Marie-Paule Strub, James R. Sellers, Thomas B. Friedman
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12390–12395. Published online Aug 11, 2014. doi: 10.1073/pnas.1409459111
PMCID:
PMC4151768
André Schütte, Anna Ermund, Christoph Becker-Pauly, Malin E. V. Johansson, Ana M. Rodriguez-Pineiro, Fredrik Bäckhed, Stefan Müller, Daniel Lottaz, Judith S. Bond, Gunnar C. Hansson
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12396–12401. Published online Aug 11, 2014. doi: 10.1073/pnas.1407597111
PMCID:
PMC4151749
A sequence-specific transcription activator motif and powerful synthetic variants that bind Mediator using a fuzzy protein interface
Linda Warfield, Lisa M. Tuttle, Derek Pacheco, Rachel E. Klevit, Steven Hahn
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): E3506–E3513. Published online Aug 13, 2014. doi: 10.1073/pnas.1412088111
PMCID:
PMC4151740

Biophysics and Computational Biology

A cellular solution to an information-processing problem
Garud Iyengar, Madan Rao
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12402–12407. Published online Aug 11, 2014. doi: 10.1073/pnas.1406608111
PMCID:
PMC4151762
Coevolutionary information, protein folding landscapes, and the thermodynamics of natural selection
Faruck Morcos, Nicholas P. Schafer, Ryan R. Cheng, José N. Onuchic, Peter G. Wolynes
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12408–12413. Published online Aug 11, 2014. doi: 10.1073/pnas.1413575111
PMCID:
PMC4151759
Characterizing the proton loading site in cytochrome c oxidase
Jianxun Lu, M. R. Gunner
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12414–12419. Published online Aug 11, 2014. doi: 10.1073/pnas.1407187111
PMCID:
PMC4151712
Engineered kinase activation reveals unique morphodynamic phenotypes and associated trafficking for Src family isoforms
Pei-Hsuan Chu, Denis Tsygankov, Matthew E. Berginski, Onur Dagliyan, Shawn M. Gomez, Timothy C. Elston, Andrei V. Karginov, Klaus M. Hahn
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12420–12425. Published online Aug 12, 2014. doi: 10.1073/pnas.1404487111
PMCID:
PMC4151743
Structural basis for the recruitment and activation of the Legionella phospholipase VipD by the host GTPase Rab5
María Lucas, Andrew H. Gaspar, Chiara Pallara, Adriana Lucely Rojas, Juan Fernández-Recio, Matthias P. Machner, Aitor Hierro
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): E3514–E3523. Published online Aug 11, 2014. doi: 10.1073/pnas.1405391111
PMCID:
PMC4151760
Luca Turin, Efthimios M. C. Skoulakis, Andrew P. Horsfield
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): E3524–E3533. Published online Aug 11, 2014. doi: 10.1073/pnas.1404387111
PMCID:
PMC4151765

Cell Biology

Mari Ohnuki, Koji Tanabe, Kenta Sutou, Ito Teramoto, Yuka Sawamura, Megumi Narita, Michiko Nakamura, Yumie Tokunaga, Masahiro Nakamura, Akira Watanabe, Shinya Yamanaka, Kazutoshi Takahashi
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12426–12431. Published online Aug 5, 2014. doi: 10.1073/pnas.1413299111
PMCID:
PMC4151758
Francis Impens, Lilliana Radoshevich, Pascale Cossart, David Ribet
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12432–12437. Published online Aug 11, 2014. doi: 10.1073/pnas.1413825111
PMCID:
PMC4151716
Distinct isoform of FABP7 revealed by screening for retroelement-activated genes in diffuse large B-cell lymphoma
Frances E. Lock, Rita Rebollo, Katharine Miceli-Royer, Liane Gagnier, Sabrina Kuah, Artem Babaian, Maialen Sistiaga-Poveda, C. Benjamin Lai, Oksana Nemirovsky, Isabel Serrano, Christian Steidl, Mohammad M. Karimi, Dixie L. Mager
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): E3534–E3543. Published online Aug 11, 2014. doi: 10.1073/pnas.1405507111
PMCID:
PMC4151764
Calcineurin determines toxic versus beneficial responses to α-synuclein
Gabriela Caraveo, Pavan K. Auluck, Luke Whitesell, Chee Yeun Chung, Valeriya Baru, Eugene V. Mosharov, Xiaohui Yan, Manu Ben-Johny, Martin Soste, Paola Picotti, Hanna Kim, Kim A. Caldwell, Guy A. Caldwell, David Sulzer, David T. Yue, Susan Lindquist
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): E3544–E3552. Published online Aug 13, 2014. doi: 10.1073/pnas.1413201111
PMCID:
PMC4151770

Developmental Biology

Primary cilia are required in a unique subpopulation of neural progenitors
Cheuk Ka Tong, Young-Goo Han, Jugal K. Shah, Kirsten Obernier, Cristina D. Guinto, Arturo Alvarez-Buylla
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12438–12443. Published online Aug 11, 2014. doi: 10.1073/pnas.1321425111
PMCID:
PMC4151724
Wnt ligand/Frizzled 2 receptor signaling regulates tube shape and branch-point formation in the lung through control of epithelial cell shape
Rachel S. Kadzik, Ethan David Cohen, Michael P. Morley, Kathleen M. Stewart, Min Min Lu, Edward E. Morrisey
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12444–12449. Published online Aug 11, 2014. doi: 10.1073/pnas.1406639111
PMCID:
PMC4151720

Genetics

Molecular pathogenesis of congenital diaphragmatic hernia revealed by exome sequencing, developmental data, and bioinformatics
Mauro Longoni, Frances A. High, Meaghan K. Russell, Alireza Kashani, Adam A. Tracy, Caroline M. Coletti, Regis Hila, Ahmed Shamia, Julie Wells, Kate G. Ackerman, Jay M. Wilson, Carol J. Bult, Charles Lee, Kasper Lage, Barbara R. Pober, Patricia K. Donahoe
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12450–12455. Published online Aug 8, 2014. doi: 10.1073/pnas.1412509111
PMCID:
PMC4151769
Predicting hybrid performance in rice using genomic best linear unbiased prediction
Shizhong Xu, Dan Zhu, Qifa Zhang
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12456–12461. Published online Aug 11, 2014. doi: 10.1073/pnas.1413750111
PMCID:
PMC4151732
Allen A. Cheng, Huiming Ding, Timothy K. Lu
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12462–12467. Published online Aug 11, 2014. doi: 10.1073/pnas.1400093111
PMCID:
PMC4151723
Small RNA combination therapy for lung cancer
Wen Xue, James E. Dahlman, Tuomas Tammela, Omar F. Khan, Sabina Sood, Apeksha Dave, Wenxin Cai, Leilani M. Chirino, Gillian R. Yang, Roderick Bronson, Denise G. Crowley, Gaurav Sahay, Avi Schroeder, Robert Langer, Daniel G. Anderson, Tyler Jacks
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): E3553–E3561. Published online Aug 11, 2014. doi: 10.1073/pnas.1412686111
PMCID:
PMC4151750

Immunology and Inflammation

Stanley Plotkin
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12283–12287. Published online Aug 18, 2014. doi: 10.1073/pnas.1400472111
PMCID:
PMC4151719
Charles Maisonneuve, Sylvie Bertholet, Dana J. Philpott, Ennio De Gregorio
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12294–12299. Published online Aug 18, 2014. doi: 10.1073/pnas.1400478111
PMCID:
PMC4151741
Bali Pulendran
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12300–12306. Published online Aug 18, 2014. doi: 10.1073/pnas.1400476111
PMCID:
PMC4151766
Thomas B. Sundberg, Hwan Geun Choi, Joo-Hye Song, Caitlin N. Russell, Mahmud M. Hussain, Daniel B. Graham, Bernard Khor, John Gagnon, Daniel J. O’Connell, Kavitha Narayan, Vlado Dančík, Jose R. Perez, Hans-Christian Reinecker, Nathanael S. Gray, Stuart L. Schreiber, Ramnik J. Xavier, Alykhan F. Shamji
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12468–12473. Published online Aug 11, 2014. doi: 10.1073/pnas.1412308111
PMCID:
PMC4151730
KLRG+ invariant natural killer T cells are long-lived effectors
Kanako Shimizu, Yusuke Sato, Jun Shinga, Takashi Watanabe, Takaho Endo, Miki Asakura, Satoru Yamasaki, Kazuyoshi Kawahara, Yuki Kinjo, Hiroshi Kitamura, Hiroshi Watarai, Yasuyuki Ishii, Moriya Tsuji, Masaru Taniguchi, Osamu Ohara, Shin-ichiro Fujii
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12474–12479. Published online Aug 12, 2014. doi: 10.1073/pnas.1406240111
PMCID:
PMC4151776
Autophagy protects C. elegans against necrosis during Pseudomonas aeruginosa infection
Cheng-Gang Zou, Yi-Cheng Ma, Li-Li Dai, Ke-Qin Zhang
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12480–12485. Published online Aug 11, 2014. doi: 10.1073/pnas.1405032111
PMCID:
PMC4151725
Margarida Rei, Natacha Gonçalves-Sousa, Telma Lança, Richard G. Thompson, Sofia Mensurado, Frances R. Balkwill, Hagen Kulbe, Daniel J. Pennington, Bruno Silva-Santos
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): E3562–E3570. Published online Aug 11, 2014. doi: 10.1073/pnas.1403424111
PMCID:
PMC4151711

Medical Sciences

Rino Rappuoli
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12282. Published online Aug 19, 2014. doi: 10.1073/pnas.1413559111
PMCID:
PMC4151739
Rino Rappuoli, Mariagrazia Pizza, Giuseppe Del Giudice, Ennio De Gregorio
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12288–12293. Published online Aug 18, 2014. doi: 10.1073/pnas.1402981111
PMCID:
PMC4151714
Calman A. MacLennan, Allan Saul
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12307–12312. Published online Aug 18, 2014. doi: 10.1073/pnas.1400473111
PMCID:
PMC4151718
Anne Le, Zachary E. Stine, Christopher Nguyen, Junaid Afzal, Peng Sun, Max Hamaker, Nicholas M. Siegel, Arvin M. Gouw, Byung-hak Kang, Shu-Han Yu, Rory L. Cochran, Kurt A. Sailor, Hongjun Song, Chi V. Dang
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12486–12491. Published online Aug 11, 2014. doi: 10.1073/pnas.1402012111
PMCID:
PMC4151727
Interleukin-1 deficiency prolongs ovarian lifespan in mice
Shiri Uri-Belapolsky, Aviv Shaish, Efrat Eliyahu, Hadas Grossman, Mattan Levi, Dana Chuderland, Lihi Ninio-Many, Noa Hasky, David Shashar, Tal Almog, Michal Kandel-Kfir, Dror Harats, Ruth Shalgi, Yehuda Kamari
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12492–12497. Published online Aug 11, 2014. doi: 10.1073/pnas.1323955111
PMCID:
PMC4151745

Microbiology

Native microbiome impedes vertical transmission of Wolbachia in Anopheles mosquitoes
Grant L. Hughes, Brittany L. Dodson, Rebecca M. Johnson, Courtney C. Murdock, Hitoshi Tsujimoto, Yasutsugu Suzuki, Alyssa A. Patt, Long Cui, Carlos W. Nossa, Rhiannon M. Barry, Joyce M. Sakamoto, Emily A. Hornett, Jason L. Rasgon
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12498–12503. Published online Aug 11, 2014. doi: 10.1073/pnas.1408888111
PMCID:
PMC4151774
Marine ammonia-oxidizing archaeal isolates display obligate mixotrophy and wide ecotypic variation
Wei Qin, Shady A. Amin, Willm Martens-Habbena, Christopher B. Walker, Hidetoshi Urakawa, Allan H. Devol, Anitra E. Ingalls, James W. Moffett, E. Virginia Armbrust, David A. Stahl
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12504–12509. Published online Aug 11, 2014. doi: 10.1073/pnas.1324115111
PMCID:
PMC4151751
Compound-gene interaction mapping reveals distinct roles for Staphylococcus aureus teichoic acids
John P. Santa Maria, Jr., Ama Sadaka, Samir H. Moussa, Stephanie Brown, Yanjia J. Zhang, Eric J. Rubin, Michael S. Gilmore, Suzanne Walker
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12510–12515. Published online Aug 7, 2014. doi: 10.1073/pnas.1404099111
PMCID:
PMC4151746
Receptor usage and cell entry of bat coronavirus HKU4 provide insight into bat-to-human transmission of MERS coronavirus
Yang Yang, Lanying Du, Chang Liu, Lili Wang, Cuiqing Ma, Jian Tang, Ralph S. Baric, Shibo Jiang, Fang Li
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12516–12521. Published online Aug 11, 2014. doi: 10.1073/pnas.1405889111
PMCID:
PMC4151778
Patterned progression of bacterial populations in the premature infant gut
Patricio S. La Rosa, Barbara B. Warner, Yanjiao Zhou, George M. Weinstock, Erica Sodergren, Carla M. Hall-Moore, Harold J. Stevens, William E. Bennett, Jr., Nurmohammad Shaikh, Laura A. Linneman, Julie A. Hoffmann, Aaron Hamvas, Elena Deych, Berkley A. Shands, William D. Shannon, Phillip I. Tarr
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12522–12527. Published online Aug 11, 2014. doi: 10.1073/pnas.1409497111
PMCID:
PMC4151715
Vectored antibody gene delivery protects against Plasmodium falciparum sporozoite challenge in mice
Cailin Deal, Alejandro B. Balazs, Diego A. Espinosa, Fidel Zavala, David Baltimore, Gary Ketner
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12528–12532. Published online Aug 11, 2014. doi: 10.1073/pnas.1407362111
PMCID:
PMC4151717

Neuroscience

Hongmei Li-Byarlay, Clare C. Rittschof, Jonathan H. Massey, Barry R. Pittendrigh, Gene E. Robinson
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12533–12537. Published online Aug 4, 2014. doi: 10.1073/pnas.1412306111
PMCID:
PMC4151721
Nicotinic and muscarinic agonists and acetylcholinesterase inhibitors stimulate a common pathway to enhance GluN2B-NMDAR responses
Masaru Ishibashi, Yoshihiko Yamazaki, Ricardo Miledi, Katumi Sumikawa
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12538–12543. Published online Aug 11, 2014. doi: 10.1073/pnas.1408805111
PMCID:
PMC4151735
DRK/DOS/SOS converge with Crk/Mbc/dCed-12 to activate Rac1 during glial engulfment of axonal debris
Tsai-Yi Lu, Johnna Doherty, Marc R. Freeman
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12544–12549. Published online Aug 6, 2014. doi: 10.1073/pnas.1403450111
PMCID:
PMC4151738
MRI-localized biopsies reveal subtype-specific differences in molecular and cellular composition at the margins of glioblastoma
Brian J. Gill, David J. Pisapia, Hani R. Malone, Hannah Goldstein, Liang Lei, Adam Sonabend, Jonathan Yun, Jorge Samanamud, Jennifer S. Sims, Matei Banu, Athanassios Dovas, Andrew F. Teich, Sameer A. Sheth, Guy M. McKhann, Michael B. Sisti, Jeffrey N. Bruce, Peter A. Sims, Peter Canoll
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12550–12555. Published online Aug 11, 2014. doi: 10.1073/pnas.1405839111
PMCID:
PMC4151734

Pharmacology

Inhibitor of MYC identified in a Kröhnke pyridine library
Jonathan R. Hart, Amanda L. Garner, Jing Yu, Yoshihiro Ito, Minghao Sun, Lynn Ueno, Jin-Kyu Rhee, Michael M. Baksh, Eduard Stefan, Markus Hartl, Klaus Bister, Peter K. Vogt, Kim D. Janda
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12556–12561. Published online Aug 11, 2014. doi: 10.1073/pnas.1319488111
PMCID:
PMC4151726

Physiology

Genetic–epigenetic dysregulation of thymic TSH receptor gene expression triggers thyroid autoimmunity
Mihaela Stefan, Chengguo Wei, Angela Lombardi, Cheuk Wun Li, Erlinda S. Concepcion, William B. Inabnet, III, Randall Owen, Weijia Zhang, Yaron Tomer
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12562–12567. Published online Aug 13, 2014. doi: 10.1073/pnas.1408821111
PMCID:
PMC4151767

Plant Biology

Kai Graeber, Ada Linkies, Tina Steinbrecher, Klaus Mummenhoff, Danuše Tarkowská, Veronika Turečková, Michael Ignatz, Katja Sperber, Antje Voegele, Hans de Jong, Terezie Urbanová, Miroslav Strnad, Gerhard Leubner-Metzger
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): E3571–E3580. Published online Aug 11, 2014. doi: 10.1073/pnas.1403851111
PMCID:
PMC4151772

Correction

Correction for Poulson-Ellestad et al., Metabolomics and proteomics reveal impacts of chemically mediated competition on marine plankton
Proc Natl Acad Sci U S A. Aug 26, 2014; 111(34): 12568. Published online Aug 11, 2014. doi: 10.1073/pnas.1413432111
PMCID:
PMC4151728

Articles from Proceedings of the National Academy of Sciences of the United States of America are provided here courtesy of National Academy of Sciences