Logo of pnasPNASInfo for AuthorsEditorial BoardAboutSubscriptions

Volume 112(7);  2015 Feb 17

Articles from this journal are usually available in PMC after a 6-month delay (embargo). Some articles may be available sooner.

This Week in PNAS

In This Issue
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1905–1906. Published online 2015 Feb 17. doi: 10.1073/iti0715112
PMCID:
PMC4343092

Letters

Mandibular evidence supports Homo floresiensis as a distinct species
Michael Carrington Westaway, Arthur C. Durband, Colin P. Groves, Mark Collard
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E604–E605. Published online 2015 Feb 6. doi: 10.1073/pnas.1418997112
PMCID:
PMC4343145
Reply to Westaway et al.: Mandibular misrepresentations fail to support the invalid species Homo floresiensis
Robert B. Eckhardt, Maciej Henneberg, Sakdapong Chavanaves, Alexander S. Weller, Kenneth J. Hsü
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E606. Published online 2015 Feb 6. doi: 10.1073/pnas.1422176112
PMCID:
PMC4343134

Opinion

Bruce Alberts, Marc W. Kirschner, Shirley Tilghman, Harold Varmus
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1912–1913. Published online 2015 Feb 17. doi: 10.1073/pnas.1500969112
PMCID:
PMC4343141

Core Concepts

Steven Ashley
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1914. Published online 2015 Feb 17. doi: 10.1073/pnas.1500429112
PMCID:
PMC4343082

Retrospective

Melford E. Spiro, 1920–2014
Roy G. D’Andrade
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1915–1916. Published online 2015 Feb 9. doi: 10.1073/pnas.1500172112
PMCID:
PMC4343101

Profile

Profile of Alberto Kornblihtt
Jennifer Viegas
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1917–1918. Published online 2014 Nov 25. doi: 10.1073/pnas.1421075111
PMCID:
PMC4343084

Commentaries

Reassessment of global gene–language coevolution
Keith Hunley
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1919–1920. Published online 2015 Feb 9. doi: 10.1073/pnas.1425000112
PMCID:
PMC4343119
Chemical proteomics reveals a second family of cyclic-di-AMP hydrolases
John D. Helmann
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1921–1922. Published online 2015 Jan 30. doi: 10.1073/pnas.1500077112
PMCID:
PMC4343114
Interchangeable allies: Exploiting development and selection to swap symbionts
Nicole M. Gerardo
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1923–1924. Published online 2015 Feb 9. doi: 10.1073/pnas.1424099112
PMCID:
PMC4343109

PNAS Plus Significance Statements

PNAS Plus Significance Statements
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1925–1928. Published online 2015 Feb 17. doi: 10.1073/pnas.ss11207
PMCID:
PMC4343162

PNAS Plus

Highly multiplexed profiling of single-cell effector functions reveals deep functional heterogeneity in response to pathogenic ligands
Yao Lu, Qiong Xue, Markus R. Eisele, Endah S. Sulistijo, Kara Brower, Lin Han, El-ad David Amir, Dana Pe’er, Kathryn Miller-Jensen, Rong Fan
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E607–E615. Published online 2015 Feb 2. doi: 10.1073/pnas.1416756112
PMCID:
PMC4343126
Mitochondrial peroxiredoxin functions as crucial chaperone reservoir in Leishmania infantum
Filipa Teixeira, Helena Castro, Tânia Cruz, Eric Tse, Philipp Koldewey, Daniel R. Southworth, Ana M. Tomás, Ursula Jakob
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E616–E624. Published online 2015 Feb 2. doi: 10.1073/pnas.1419682112
PMCID:
PMC4343147
Distinct activation of an E2 ubiquitin-conjugating enzyme by its cognate E3 ligases
Itamar Cohen, Reuven Wiener, Yuval Reiss, Tommer Ravid
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E625–E632. Published online 2015 Feb 2. doi: 10.1073/pnas.1415621112
PMCID:
PMC4343096
Stanislaw K. Jozwiakowski, Farimah Borazjani Gholami, Aidan J. Doherty
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E633–E638. Published online 2015 Feb 2. doi: 10.1073/pnas.1412982112
PMCID:
PMC4343091
CryoEM and mutagenesis reveal that the smallest capsid protein cements and stabilizes Kaposi's sarcoma-associated herpesvirus capsid
Xinghong Dai, Danyang Gong, Yuchen Xiao, Ting-Ting Wu, Ren Sun, Z. Hong Zhou
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E649–E656. Published online 2015 Feb 2. doi: 10.1073/pnas.1420317112
PMCID:
PMC4343125
Autoinhibition and relief mechanism for Polo-like kinase 4
Joseph E. Klebba, Daniel W. Buster, Tiffany A. McLamarrah, Nasser M. Rusan, Gregory C. Rogers
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E657–E666. Published online 2015 Feb 2. doi: 10.1073/pnas.1417967112
PMCID:
PMC4343128
Peter Hoboth, Andreas Müller, Anna Ivanova, Hassan Mziaut, Jaber Dehghany, Anke Sönmez, Martina Lachnit, Michael Meyer-Hermann, Yannis Kalaidzidis, Michele Solimena
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E667–E676. Published online 2015 Feb 2. doi: 10.1073/pnas.1409542112
PMCID:
PMC4343180
Rodrigo Peña-Hernández, Maud Marques, Khalid Hilmi, Teijun Zhao, Amine Saad, Moulay A. Alaoui-Jamali, Sonia V. del Rincon, Todd Ashworth, Ananda L. Roy, Beverly M. Emerson, Michael Witcher
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E677–E686. Published online 2015 Feb 2. doi: 10.1073/pnas.1416674112
PMCID:
PMC4343169
The autophagic machinery ensures nonlytic transmission of mycobacteria
Lilli Gerstenmaier, Rachel Pilla, Lydia Herrmann, Hendrik Herrmann, Monica Prado, Geno J. Villafano, Margot Kolonko, Rudolph Reimer, Thierry Soldati, Jason S. King, Monica Hagedorn
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E687–E692. Published online 2015 Feb 2. doi: 10.1073/pnas.1423318112
PMCID:
PMC4343083
Bacterial proteins pinpoint a single eukaryotic root
Romain Derelle, Guifré Torruella, Vladimír Klimeš, Henner Brinkmann, Eunsoo Kim, Čestmír Vlček, B. Franz Lang, Marek Eliáš
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E693–E699. Published online 2015 Feb 2. doi: 10.1073/pnas.1420657112
PMCID:
PMC4343179
PTEN regulates natural killer cell trafficking in vivo
Jeffrey W. Leong, Stephanie E. Schneider, Ryan P. Sullivan, Bijal A. Parikh, Bryan A. Anthony, Anvita Singh, Brea A. Jewell, Timothy Schappe, Julia A. Wagner, Daniel C. Link, Wayne M. Yokoyama, Todd A. Fehniger
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E700–E709. Published online 2015 Feb 2. doi: 10.1073/pnas.1413886112
PMCID:
PMC4343124
Suppression of systemic autoimmunity by the innate immune adaptor STING
Shruti Sharma, Allison M. Campbell, Jennie Chan, Stefan A. Schattgen, Gregory M. Orlowski, Ribhu Nayar, Annie H. Huyler, Kerstin Nündel, Chandra Mohan, Leslie J. Berg, Mark J. Shlomchik, Ann Marshak-Rothstein, Katherine A. Fitzgerald
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E710–E717. Published online 2015 Feb 2. doi: 10.1073/pnas.1420217112
PMCID:
PMC4343138
The SWI/SNF chromatin remodeling complex regulates germinal center formation by repressing Blimp-1 expression
Jinwook Choi, Shin Jeon, Seungjin Choi, Kyungsoo Park, Rho Hyun Seong
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E718–E727. Published online 2015 Feb 2. doi: 10.1073/pnas.1418592112
PMCID:
PMC4343085
Lirong Wei, Richard Chahwan, Shanzhi Wang, Xiaohua Wang, Phuong T. Pham, Myron F. Goodman, Aviv Bergman, Matthew D. Scharff, Thomas MacCarthy
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E728–E737. Published online 2015 Feb 2. doi: 10.1073/pnas.1500788112
PMCID:
PMC4343087
Adverse childhood experiences and physiological wear-and-tear in midlife: Findings from the 1958 British birth cohort
Cristina Barboza Solís, Michelle Kelly-Irving, Romain Fantin, Muriel Darnaudéry, Jérôme Torrisani, Thierry Lang, Cyrille Delpierre
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E738–E746. Published online 2015 Feb 2. doi: 10.1073/pnas.1417325112
PMCID:
PMC4343178
An HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence
TuAnh Ngoc Huynh, Shukun Luo, Daniel Pensinger, John-Demian Sauer, Liang Tong, Joshua J. Woodward
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E747–E756. Published online 2015 Jan 12. doi: 10.1073/pnas.1416485112
PMCID:
PMC4343097
Novel mixed-linkage β-glucan activated by c-di-GMP in Sinorhizobium meliloti
Daniel Pérez-Mendoza, Miguel Ángel Rodríguez-Carvajal, Lorena Romero-Jiménez, Gabriela de Araujo Farias, Javier Lloret, María Trinidad Gallegos, Juan Sanjuán
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E757–E765. Published online 2015 Feb 3. doi: 10.1073/pnas.1421748112
PMCID:
PMC4343143
Differential RNA-seq of Vibrio cholerae identifies the VqmR small RNA as a regulator of biofilm formation
Kai Papenfort, Konrad U. Förstner, Jian-Ping Cong, Cynthia M. Sharma, Bonnie L. Bassler
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E766–E775. Published online 2015 Feb 2. doi: 10.1073/pnas.1500203112
PMCID:
PMC4343088
Two-photon brightness of azobenzene photoswitches designed for glutamate receptor optogenetics
Elizabeth C. Carroll, Shai Berlin, Joshua Levitz, Michael A. Kienzler, Zhe Yuan, Dorte Madsen, Delmar S. Larsen, Ehud Y. Isacoff
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E776–E785. Published online 2015 Feb 4. doi: 10.1073/pnas.1416942112
PMCID:
PMC4343171
Regulator of G protein signaling 6 is a critical mediator of both reward-related behavioral and pathological responses to alcohol
Adele Stewart, Biswanath Maity, Simon P. Anderegg, Chantal Allamargot, Jianqi Yang, Rory A. Fisher
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E786–E795. Published online 2015 Feb 2. doi: 10.1073/pnas.1418795112
PMCID:
PMC4343156
Potassium channelopathy-like defect underlies early-stage cerebrovascular dysfunction in a genetic model of small vessel disease
Fabrice Dabertrand, Christel Krøigaard, Adrian D. Bonev, Emmanuel Cognat, Thomas Dalsgaard, Valérie Domenga-Denier, David C. Hill-Eubanks, Joseph E. Brayden, Anne Joutel, Mark T. Nelson
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E796–E805. Published online 2015 Feb 2. doi: 10.1073/pnas.1420765112
PMCID:
PMC4343103
Siamsa M. Doyle, Ash Haeger, Thomas Vain, Adeline Rigal, Corrado Viotti, Małgorzata Łangowska, Qian Ma, Jiří Friml, Natasha V. Raikhel, Glenn R. Hicks, Stéphanie Robert
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E806–E815. Published online 2015 Feb 2. doi: 10.1073/pnas.1424856112
PMCID:
PMC4343110

Perspective

Ergodic theorem, ergodic theory, and statistical mechanics
Calvin C. Moore
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1907–1911. Published online 2015 Feb 17. doi: 10.1073/pnas.1421798112
PMCID:
PMC4343160

Physical Sciences

Applied Physical Sciences

Suppression of phase separation and giant enhancement of superconducting transition temperature in FeSe1−xTex thin films
Yoshinori Imai, Yuichi Sawada, Fuyuki Nabeshima, Atsutaka Maeda
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1937–1940. Published online 2015 Feb 2. doi: 10.1073/pnas.1418994112
PMCID:
PMC4343111
The spontaneous emergence of conventions: An experimental study of cultural evolution
Damon Centola, Andrea Baronchelli
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1989–1994. Published online 2015 Feb 2. doi: 10.1073/pnas.1418838112
PMCID:
PMC4343158

Chemistry

Katharina Schücker, Thorge Holm, Christian Franke, Markus Sauer, Ricardo Benavente
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2029–2033. Published online 2015 Feb 2. doi: 10.1073/pnas.1414814112
PMCID:
PMC4343094

Earth, Atmospheric, and Planetary Sciences

Kathryn McKain, Adrian Down, Steve M. Raciti, John Budney, Lucy R. Hutyra, Cody Floerchinger, Scott C. Herndon, Thomas Nehrkorn, Mark S. Zahniser, Robert B. Jackson, Nathan Phillips, Steven C. Wofsy
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1941–1946. Published online 2015 Jan 23. doi: 10.1073/pnas.1416261112
PMCID:
PMC4343086
Droplet fragmentation: 3D imaging of a previously unidentified pore-scale process during multiphase flow in porous media
Tannaz Pak, Ian B. Butler, Sebastian Geiger, Marinus I. J. van Dijke, Ken S. Sorbie
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1947–1952. Published online 2015 Feb 2. doi: 10.1073/pnas.1420202112
PMCID:
PMC4343173
Sulfur-cycling fossil bacteria from the 1.8-Ga Duck Creek Formation provide promising evidence of evolution's null hypothesis
J. William Schopf, Anatoliy B. Kudryavtsev, Malcolm R. Walter, Martin J. Van Kranendonk, Kenneth H. Williford, Reinhard Kozdon, John W. Valley, Victor A. Gallardo, Carola Espinoza, David T. Flannery
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2087–2092. Published online 2015 Feb 2. doi: 10.1073/pnas.1419241112
PMCID:
PMC4343172
Mandibular evidence supports Homo floresiensis as a distinct species
Michael Carrington Westaway, Arthur C. Durband, Colin P. Groves, Mark Collard
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E604–E605. Published online 2015 Feb 6. doi: 10.1073/pnas.1418997112
PMCID:
PMC4343145
Reply to Westaway et al.: Mandibular misrepresentations fail to support the invalid species Homo floresiensis
Robert B. Eckhardt, Maciej Henneberg, Sakdapong Chavanaves, Alexander S. Weller, Kenneth J. Hsü
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E606. Published online 2015 Feb 6. doi: 10.1073/pnas.1422176112
PMCID:
PMC4343134

Engineering

Dynamic phototuning of 3D hydrogel stiffness
Ryan S. Stowers, Shane C. Allen, Laura J. Suggs
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1953–1958. Published online 2015 Feb 2. doi: 10.1073/pnas.1421897112
PMCID:
PMC4343123
Gold–silica quantum rattles for multimodal imaging and therapy
Mathew Hembury, Ciro Chiappini, Sergio Bertazzo, Tammy L. Kalber, Glenna L. Drisko, Olumide Ogunlade, Simon Walker-Samuel, Katla Sai Krishna, Coline Jumeaux, Paul Beard, Challa S. S. R. Kumar, Alexandra E. Porter, Mark F. Lythgoe, Cédric Boissière, Clément Sanchez, Molly M. Stevens
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1959–1964. Published online 2015 Feb 4. doi: 10.1073/pnas.1419622112
PMCID:
PMC4343080
Highly multiplexed profiling of single-cell effector functions reveals deep functional heterogeneity in response to pathogenic ligands
Yao Lu, Qiong Xue, Markus R. Eisele, Endah S. Sulistijo, Kara Brower, Lin Han, El-ad David Amir, Dana Pe’er, Kathryn Miller-Jensen, Rong Fan
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E607–E615. Published online 2015 Feb 2. doi: 10.1073/pnas.1416756112
PMCID:
PMC4343126

Mathematics

Ergodic theorem, ergodic theory, and statistical mechanics
Calvin C. Moore
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1907–1911. Published online 2015 Feb 17. doi: 10.1073/pnas.1421798112
PMCID:
PMC4343160
Steven Ashley
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1914. Published online 2015 Feb 17. doi: 10.1073/pnas.1500429112
PMCID:
PMC4343082

Physics

Scaling laws describe memories of host–pathogen riposte in the HIV population
John P. Barton, Mehran Kardar, Arup K. Chakraborty
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1965–1970. Published online 2015 Feb 2. doi: 10.1073/pnas.1415386112
PMCID:
PMC4343148
Magnetic nanopantograph in the SrCu2(BO3)2 Shastry–Sutherland lattice
Guillaume Radtke, Andrés Saúl, Hanna A. Dabkowska, Myron B. Salamon, Marcelo Jaime
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1971–1976. Published online 2015 Feb 2. doi: 10.1073/pnas.1421414112
PMCID:
PMC4343170

Sustainability Science

Rapid loss of lakes on the Mongolian Plateau
Shengli Tao, Jingyun Fang, Xia Zhao, Shuqing Zhao, Haihua Shen, Huifeng Hu, Zhiyao Tang, Zhiheng Wang, Qinghua Guo
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2281–2286. Published online 2015 Feb 2. doi: 10.1073/pnas.1411748112
PMCID:
PMC4343146

Social Sciences

Psychological and Cognitive Sciences

Self-affirmation alters the brain’s response to health messages and subsequent behavior change
Emily B. Falk, Matthew Brook O’Donnell, Christopher N. Cascio, Francis Tinney, Yoona Kang, Matthew D. Lieberman, Shelley E. Taylor, Lawrence An, Kenneth Resnicow, Victor J. Strecher
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1977–1982. Published online 2015 Feb 2. doi: 10.1073/pnas.1500247112
PMCID:
PMC4343089
Role of the motor system in language knowledge
Iris Berent, Anna-Katharine Brem, Xu Zhao, Erica Seligson, Hong Pan, Jane Epstein, Emily Stern, Albert M. Galaburda, Alvaro Pascual-Leone
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1983–1988. Published online 2015 Feb 2. doi: 10.1073/pnas.1416851112
PMCID:
PMC4343166

Sustainability Science

Kathryn McKain, Adrian Down, Steve M. Raciti, John Budney, Lucy R. Hutyra, Cody Floerchinger, Scott C. Herndon, Thomas Nehrkorn, Mark S. Zahniser, Robert B. Jackson, Nathan Phillips, Steven C. Wofsy
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1941–1946. Published online 2015 Jan 23. doi: 10.1073/pnas.1416261112
PMCID:
PMC4343086

Social Sciences

The spontaneous emergence of conventions: An experimental study of cultural evolution
Damon Centola, Andrea Baronchelli
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1989–1994. Published online 2015 Feb 2. doi: 10.1073/pnas.1418838112
PMCID:
PMC4343158

Biological Sciences

Applied Biological Sciences

Dynamic phototuning of 3D hydrogel stiffness
Ryan S. Stowers, Shane C. Allen, Laura J. Suggs
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1953–1958. Published online 2015 Feb 2. doi: 10.1073/pnas.1421897112
PMCID:
PMC4343123
Tunable control of antibody immobilization using electric field
Sam Emaminejad, Mehdi Javanmard, Chaitanya Gupta, Shuai Chang, Ronald W. Davis, Roger T. Howe
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1995–1999. Published online 2015 Feb 3. doi: 10.1073/pnas.1424592112
PMCID:
PMC4343132
Glycosylation profiles determine extravasation and disease-targeting properties of armed antibodies
Dario Venetz, Christian Hess, Chia-wei Lin, Markus Aebi, Dario Neri
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2000–2005. Published online 2015 Feb 2. doi: 10.1073/pnas.1416694112
PMCID:
PMC4343149

Biochemistry

Structural basis for transcription reactivation by RapA
Bin Liu, Yuhong Zuo, Thomas A. Steitz
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2006–2010. Published online 2015 Feb 2. doi: 10.1073/pnas.1417152112
PMCID:
PMC4343176
Inhibition of the β-barrel assembly machine by a peptide that binds BamD
Christine L. Hagan, Joseph S. Wzorek, Daniel Kahne
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2011–2016. Published online 2015 Feb 2. doi: 10.1073/pnas.1415955112
PMCID:
PMC4343090
Distinct pathways of RNA polymerase regulation by a phage-encoded factor
Daria Esyunina, Evgeny Klimuk, Konstantin Severinov, Andrey Kulbachinskiy
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2017–2022. Published online 2015 Feb 2. doi: 10.1073/pnas.1416330112
PMCID:
PMC4343175
A CaMKII/PDE4D negative feedback regulates cAMP signaling
Delphine Mika, Wito Richter, Marco Conti
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2023–2028. Published online 2015 Feb 2. doi: 10.1073/pnas.1419992112
PMCID:
PMC4343159
Mitochondrial peroxiredoxin functions as crucial chaperone reservoir in Leishmania infantum
Filipa Teixeira, Helena Castro, Tânia Cruz, Eric Tse, Philipp Koldewey, Daniel R. Southworth, Ana M. Tomás, Ursula Jakob
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E616–E624. Published online 2015 Feb 2. doi: 10.1073/pnas.1419682112
PMCID:
PMC4343147
Distinct activation of an E2 ubiquitin-conjugating enzyme by its cognate E3 ligases
Itamar Cohen, Reuven Wiener, Yuval Reiss, Tommer Ravid
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E625–E632. Published online 2015 Feb 2. doi: 10.1073/pnas.1415621112
PMCID:
PMC4343096
Stanislaw K. Jozwiakowski, Farimah Borazjani Gholami, Aidan J. Doherty
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E633–E638. Published online 2015 Feb 2. doi: 10.1073/pnas.1412982112
PMCID:
PMC4343091

Biophysics and Computational Biology

Scaling laws describe memories of host–pathogen riposte in the HIV population
John P. Barton, Mehran Kardar, Arup K. Chakraborty
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1965–1970. Published online 2015 Feb 2. doi: 10.1073/pnas.1415386112
PMCID:
PMC4343148
Katharina Schücker, Thorge Holm, Christian Franke, Markus Sauer, Ricardo Benavente
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2029–2033. Published online 2015 Feb 2. doi: 10.1073/pnas.1414814112
PMCID:
PMC4343094
Residue-level resolution of alphavirus envelope protein interactions in pH-dependent fusion
Xiancheng Zeng, Suchetana Mukhopadhyay, Charles L. Brooks, III
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2034–2039. Published online 2015 Feb 2. doi: 10.1073/pnas.1414190112
PMCID:
PMC4343099
Proton-coupled electron transfer and the role of water molecules in proton pumping by cytochrome c oxidase
Vivek Sharma, Giray Enkavi, Ilpo Vattulainen, Tomasz Róg, Mårten Wikström
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2040–2045. Published online 2015 Feb 2. doi: 10.1073/pnas.1409543112
PMCID:
PMC4343153
Single liposome analysis of peptide translocation by the ABC transporter TAPL
Tina Zollmann, Gemma Moiset, Franz Tumulka, Robert Tampé, Bert Poolman, Rupert Abele
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2046–2051. Published online 2015 Feb 2. doi: 10.1073/pnas.1418100112
PMCID:
PMC4343155
Absence of knots in known RNA structures
Cristian Micheletti, Marco Di Stefano, Henri Orland
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2052–2057. Published online 2015 Feb 2. doi: 10.1073/pnas.1418445112
PMCID:
PMC4343165
Phylogenomics with paralogs
Marc Hellmuth, Nicolas Wieseke, Marcus Lechner, Hans-Peter Lenhof, Martin Middendorf, Peter F. Stadler
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2058–2063. Published online 2015 Jan 30. doi: 10.1073/pnas.1412770112
PMCID:
PMC4343152
Molecular mechanisms underlying the effect of the novel BK channel opener GoSlo: Involvement of the S4/S5 linker and the S6 segment
Timothy I. Webb, Aravind Singh Kshatri, Roddy J. Large, Adebola Morayo Akande, Subhrangsu Roy, Gerard P. Sergeant, Noel G. McHale, Keith D. Thornbury, Mark A. Hollywood
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2064–2069. Published online 2015 Feb 4. doi: 10.1073/pnas.1400555112
PMCID:
PMC4343142
CryoEM and mutagenesis reveal that the smallest capsid protein cements and stabilizes Kaposi's sarcoma-associated herpesvirus capsid
Xinghong Dai, Danyang Gong, Yuchen Xiao, Ting-Ting Wu, Ren Sun, Z. Hong Zhou
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E649–E656. Published online 2015 Feb 2. doi: 10.1073/pnas.1420317112
PMCID:
PMC4343125

Cell Biology

Autoinhibition and relief mechanism for Polo-like kinase 4
Joseph E. Klebba, Daniel W. Buster, Tiffany A. McLamarrah, Nasser M. Rusan, Gregory C. Rogers
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E657–E666. Published online 2015 Feb 2. doi: 10.1073/pnas.1417967112
PMCID:
PMC4343128
Peter Hoboth, Andreas Müller, Anna Ivanova, Hassan Mziaut, Jaber Dehghany, Anke Sönmez, Martina Lachnit, Michael Meyer-Hermann, Yannis Kalaidzidis, Michele Solimena
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E667–E676. Published online 2015 Feb 2. doi: 10.1073/pnas.1409542112
PMCID:
PMC4343180
Rodrigo Peña-Hernández, Maud Marques, Khalid Hilmi, Teijun Zhao, Amine Saad, Moulay A. Alaoui-Jamali, Sonia V. del Rincon, Todd Ashworth, Ananda L. Roy, Beverly M. Emerson, Michael Witcher
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E677–E686. Published online 2015 Feb 2. doi: 10.1073/pnas.1416674112
PMCID:
PMC4343169
The autophagic machinery ensures nonlytic transmission of mycobacteria
Lilli Gerstenmaier, Rachel Pilla, Lydia Herrmann, Hendrik Herrmann, Monica Prado, Geno J. Villafano, Margot Kolonko, Rudolph Reimer, Thierry Soldati, Jason S. King, Monica Hagedorn
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E687–E692. Published online 2015 Feb 2. doi: 10.1073/pnas.1423318112
PMCID:
PMC4343083

Developmental Biology

Analysis of gene–environment interactions in postnatal development of the mammalian intestine
Seth Rakoff-Nahoum, Yong Kong, Steven H. Kleinstein, Sathish Subramanian, Philip P. Ahern, Jeffrey I. Gordon, Ruslan Medzhitov
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1929–1936. Published online 2015 Feb 10. doi: 10.1073/pnas.1424886112
PMCID:
PMC4343130
Adipogenesis and epicardial adipose tissue: A novel fate of the epicardium induced by mesenchymal transformation and PPARγ activation
Yukiko Yamaguchi, Susana Cavallero, Michaela Patterson, Hua Shen, Jian Xu, S. Ram Kumar, Henry M. Sucov
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2070–2075. Published online 2015 Feb 2. doi: 10.1073/pnas.1417232112
PMCID:
PMC4343131

Ecology

Matthieu Leray, Nancy Knowlton
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2076–2081. Published online 2015 Feb 2. doi: 10.1073/pnas.1424997112
PMCID:
PMC4343139

Environmental Sciences

Breakdown of coral colonial form under reduced pH conditions is initiated in polyps and mediated through apoptosis
Hagit Kvitt, Esti Kramarsky-Winter, Keren Maor-Landaw, Keren Zandbank, Ariel Kushmaro, Hanna Rosenfeld, Maoz Fine, Dan Tchernov
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2082–2086. Published online 2015 Feb 2. doi: 10.1073/pnas.1419621112
PMCID:
PMC4343167

Evolution

Reassessment of global gene–language coevolution
Keith Hunley
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1919–1920. Published online 2015 Feb 9. doi: 10.1073/pnas.1425000112
PMCID:
PMC4343119
Interchangeable allies: Exploiting development and selection to swap symbionts
Nicole M. Gerardo
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1923–1924. Published online 2015 Feb 9. doi: 10.1073/pnas.1424099112
PMCID:
PMC4343109
Sulfur-cycling fossil bacteria from the 1.8-Ga Duck Creek Formation provide promising evidence of evolution's null hypothesis
J. William Schopf, Anatoliy B. Kudryavtsev, Malcolm R. Walter, Martin J. Van Kranendonk, Kenneth H. Williford, Reinhard Kozdon, John W. Valley, Victor A. Gallardo, Carola Espinoza, David T. Flannery
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2087–2092. Published online 2015 Feb 2. doi: 10.1073/pnas.1419241112
PMCID:
PMC4343172
Experimental replacement of an obligate insect symbiont
Nancy A. Moran, Yueli Yun
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2093–2096. Published online 2015 Jan 5. doi: 10.1073/pnas.1420037112
PMCID:
PMC4343100
Rate of language evolution is affected by population size
Lindell Bromham, Xia Hua, Thomas G. Fitzpatrick, Simon J. Greenhill
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2097–2102. Published online 2015 Feb 2. doi: 10.1073/pnas.1419704112
PMCID:
PMC4343108
Alba Jiménez, Andreea Munteanu, James Sharpe
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2103–2108. Published online 2015 Feb 2. doi: 10.1073/pnas.1411065112
PMCID:
PMC4343095
Barbara Arbeithuber, Andrea J. Betancourt, Thomas Ebner, Irene Tiemann-Boege
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2109–2114. Published online 2015 Feb 2. doi: 10.1073/pnas.1416622112
PMCID:
PMC4343121
Bernhard Voelkl, Steven J. Portugal, Markus Unsöld, James R. Usherwood, Alan M. Wilson, Johannes Fritz
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2115–2120. Published online 2015 Feb 2. doi: 10.1073/pnas.1413589112
PMCID:
PMC4343164
Mandibular evidence supports Homo floresiensis as a distinct species
Michael Carrington Westaway, Arthur C. Durband, Colin P. Groves, Mark Collard
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E604–E605. Published online 2015 Feb 6. doi: 10.1073/pnas.1418997112
PMCID:
PMC4343145
Reply to Westaway et al.: Mandibular misrepresentations fail to support the invalid species Homo floresiensis
Robert B. Eckhardt, Maciej Henneberg, Sakdapong Chavanaves, Alexander S. Weller, Kenneth J. Hsü
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E606. Published online 2015 Feb 6. doi: 10.1073/pnas.1422176112
PMCID:
PMC4343134
Bacterial proteins pinpoint a single eukaryotic root
Romain Derelle, Guifré Torruella, Vladimír Klimeš, Henner Brinkmann, Eunsoo Kim, Čestmír Vlček, B. Franz Lang, Marek Eliáš
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E693–E699. Published online 2015 Feb 2. doi: 10.1073/pnas.1420657112
PMCID:
PMC4343179

Genetics

Urbain Weyemi, Christophe E. Redon, Towqir Aziz, Rohini Choudhuri, Daisuke Maeda, Palak R. Parekh, Michael Y. Bonner, Jack L. Arbiser, William M. Bonner
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2121–2126. Published online 2015 Feb 2. doi: 10.1073/pnas.1418139112
PMCID:
PMC4343117
Simon Fortier, Tara MacRae, Mélanie Bilodeau, Tobias Sargeant, Guy Sauvageau
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2127–2132. Published online 2015 Feb 2. doi: 10.1073/pnas.1418845112
PMCID:
PMC4343140
Double-stranded RNA made in C. elegans neurons can enter the germline and cause transgenerational gene silencing
Sindhuja Devanapally, Snusha Ravikumar, Antony M. Jose
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2133–2138. Published online 2015 Feb 2. doi: 10.1073/pnas.1423333112
PMCID:
PMC4343102

Immunology and Inflammation

Noninvasive mapping of pancreatic inflammation in recent-onset type-1 diabetes patients
Jason L. Gaglia, Mukesh Harisinghani, Iman Aganj, Gregory R. Wojtkiewicz, Sandeep Hedgire, Christophe Benoist, Diane Mathis, Ralph Weissleder
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2139–2144. Published online 2015 Feb 3. doi: 10.1073/pnas.1424993112
PMCID:
PMC4343112
Mingye Feng, James Y. Chen, Rachel Weissman-Tsukamoto, Jens-Peter Volkmer, Po Yi Ho, Kelly M. McKenna, Samuel Cheshier, Michael Zhang, Nan Guo, Phung Gip, Siddhartha S. Mitra, Irving L. Weissman
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2145–2150. Published online 2015 Feb 2. doi: 10.1073/pnas.1424907112
PMCID:
PMC4343163
Physical detection of influenza A epitopes identifies a stealth subset on human lung epithelium evading natural CD8 immunity
Derin B. Keskin, Bruce B. Reinhold, Guang Lan Zhang, Alexander R. Ivanov, Barry L. Karger, Ellis L. Reinherz
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2151–2156. Published online 2015 Feb 2. doi: 10.1073/pnas.1423482112
PMCID:
PMC4343122
Andrea Björkman, Per Qvist, Likun Du, Margarita Bartish, Apostolos Zaravinos, Konstantinos Georgiou, Anders D. Børglum, Richard A. Gatti, Therese Törngren, Qiang Pan-Hammarström
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2157–2162. Published online 2015 Feb 2. doi: 10.1073/pnas.1418947112
PMCID:
PMC4343177
Emmanuella Guenova, Yuliya Skabytska, Wolfram Hoetzenecker, Günther Weindl, Karin Sauer, Manuela Tham, Kyu-Won Kim, Ji-Hyeon Park, Ji Hae Seo, Desislava Ignatova, Antonio Cozzio, Mitchell P. Levesque, Thomas Volz, Martin Köberle, Susanne Kaesler, Peter Thomas, Reinhard Mailhammer, Kamran Ghoreschi, Knut Schäkel, Boyko Amarov, Martin Eichner, Martin Schaller, Rachael A. Clark, Martin Röcken, Tilo Biedermann
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2163–2168. Published online 2015 Feb 2. doi: 10.1073/pnas.1416922112
PMCID:
PMC4343151
PTEN regulates natural killer cell trafficking in vivo
Jeffrey W. Leong, Stephanie E. Schneider, Ryan P. Sullivan, Bijal A. Parikh, Bryan A. Anthony, Anvita Singh, Brea A. Jewell, Timothy Schappe, Julia A. Wagner, Daniel C. Link, Wayne M. Yokoyama, Todd A. Fehniger
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E700–E709. Published online 2015 Feb 2. doi: 10.1073/pnas.1413886112
PMCID:
PMC4343124
Suppression of systemic autoimmunity by the innate immune adaptor STING
Shruti Sharma, Allison M. Campbell, Jennie Chan, Stefan A. Schattgen, Gregory M. Orlowski, Ribhu Nayar, Annie H. Huyler, Kerstin Nündel, Chandra Mohan, Leslie J. Berg, Mark J. Shlomchik, Ann Marshak-Rothstein, Katherine A. Fitzgerald
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E710–E717. Published online 2015 Feb 2. doi: 10.1073/pnas.1420217112
PMCID:
PMC4343138
The SWI/SNF chromatin remodeling complex regulates germinal center formation by repressing Blimp-1 expression
Jinwook Choi, Shin Jeon, Seungjin Choi, Kyungsoo Park, Rho Hyun Seong
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E718–E727. Published online 2015 Feb 2. doi: 10.1073/pnas.1418592112
PMCID:
PMC4343085
Lirong Wei, Richard Chahwan, Shanzhi Wang, Xiaohua Wang, Phuong T. Pham, Myron F. Goodman, Aviv Bergman, Matthew D. Scharff, Thomas MacCarthy
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E728–E737. Published online 2015 Feb 2. doi: 10.1073/pnas.1500788112
PMCID:
PMC4343087

Medical Sciences

Gold–silica quantum rattles for multimodal imaging and therapy
Mathew Hembury, Ciro Chiappini, Sergio Bertazzo, Tammy L. Kalber, Glenna L. Drisko, Olumide Ogunlade, Simon Walker-Samuel, Katla Sai Krishna, Coline Jumeaux, Paul Beard, Challa S. S. R. Kumar, Alexandra E. Porter, Mark F. Lythgoe, Cédric Boissière, Clément Sanchez, Molly M. Stevens
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1959–1964. Published online 2015 Feb 4. doi: 10.1073/pnas.1419622112
PMCID:
PMC4343080
TCL1 targeting miR-3676 is codeleted with tumor protein p53 in chronic lymphocytic leukemia
Veronica Balatti, Lara Rizzotto, Cecelia Miller, Alexey Palamarchuk, Paolo Fadda, Rosantony Pandolfo, Laura Z. Rassenti, Erin Hertlein, Amy S. Ruppert, Arletta Lozanski, Gerard Lozanski, Thomas J. Kipps, John C. Byrd, Carlo M. Croce, Yuri Pekarsky
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2169–2174. Published online 2015 Feb 2. doi: 10.1073/pnas.1500010112
PMCID:
PMC4343115
Adverse childhood experiences and physiological wear-and-tear in midlife: Findings from the 1958 British birth cohort
Cristina Barboza Solís, Michelle Kelly-Irving, Romain Fantin, Muriel Darnaudéry, Jérôme Torrisani, Thierry Lang, Cyrille Delpierre
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E738–E746. Published online 2015 Feb 2. doi: 10.1073/pnas.1417325112
PMCID:
PMC4343178

Microbiology

Chemical proteomics reveals a second family of cyclic-di-AMP hydrolases
John D. Helmann
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1921–1922. Published online 2015 Jan 30. doi: 10.1073/pnas.1500077112
PMCID:
PMC4343114
Age-related immune clearance of hepatitis B virus infection requires the establishment of gut microbiota
Han-Hsuan Chou, Wei-Hung Chien, Li-Ling Wu, Chi-Hung Cheng, Chen-Han Chung, Jau-Haw Horng, Yen-Hsuan Ni, Hong-Tai Tseng, Dafei Wu, Xuemei Lu, Hurng-Yi Wang, Pei-Jer Chen, Ding-Shinn Chen
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2175–2180. Published online 2015 Feb 2. doi: 10.1073/pnas.1424775112
PMCID:
PMC4343154
Generation of reactive oxygen species by lethal attacks from competing microbes
Tao G. Dong, Shiqi Dong, Christy Catalano, Richard Moore, Xiaoye Liang, John J. Mekalanos
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2181–2186. Published online 2015 Feb 2. doi: 10.1073/pnas.1425007112
PMCID:
PMC4343105
Quorum sensing and policing of Pseudomonas aeruginosa social cheaters
Meizhen Wang, Amy L. Schaefer, Ajai A. Dandekar, E. Peter Greenberg
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2187–2191. Published online 2015 Feb 2. doi: 10.1073/pnas.1500704112
PMCID:
PMC4343120
Characterization of nonprimate hepacivirus and construction of a functional molecular clone
Troels K. H. Scheel, Amit Kapoor, Eiko Nishiuchi, Kenny V. Brock, Yingpu Yu, Linda Andrus, Meigang Gu, Randall W. Renshaw, Edward J. Dubovi, Sean P. McDonough, Gerlinde R. Van de Walle, W. Ian Lipkin, Thomas J. Divers, Bud C. Tennant, Charles M. Rice
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2192–2197. Published online 2015 Feb 2. doi: 10.1073/pnas.1500265112
PMCID:
PMC4343093
Cross-talk and regulatory interactions between the essential response regulator RpaB and cyanobacterial circadian clock output
Javier Espinosa, Joseph S. Boyd, Raquel Cantos, Paloma Salinas, Susan S. Golden, Asuncion Contreras
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2198–2203. Published online 2015 Feb 4. doi: 10.1073/pnas.1424632112
PMCID:
PMC4343135
An intermolecular electrostatic interaction controls the prepore-to-pore transition in a cholesterol-dependent cytolysin
Kristin R. Wade, Eileen M. Hotze, Michael J. Kuiper, Craig J. Morton, Michael W. Parker, Rodney K. Tweten
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2204–2209. Published online 2015 Feb 2. doi: 10.1073/pnas.1423754112
PMCID:
PMC4343107
Noncanonical coproporphyrin-dependent bacterial heme biosynthesis pathway that does not use protoporphyrin
Harry A. Dailey, Svetlana Gerdes, Tamara A. Dailey, Joseph S. Burch, John D. Phillips
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2210–2215. Published online 2015 Feb 2. doi: 10.1073/pnas.1416285112
PMCID:
PMC4343137
TCF1 and LEF1 act as T-cell intrinsic HTLV-1 antagonists by targeting Tax
Guangyong Ma, Jun-ichirou Yasunaga, Hirofumi Akari, Masao Matsuoka
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2216–2221. Published online 2015 Feb 2. doi: 10.1073/pnas.1419198112
PMCID:
PMC4343127
N2 gas is an effective fertilizer for bioethanol production by Zymomonas mobilis
Timothy A. Kremer, Breah LaSarre, Amanda L. Posto, James B. McKinlay
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2222–2226. Published online 2015 Feb 2. doi: 10.1073/pnas.1420663112
PMCID:
PMC4343144
Nikesh Patel, Eric C. Dykeman, Robert H. A. Coutts, George P. Lomonossoff, David J. Rowlands, Simon E. V. Phillips, Neil Ranson, Reidun Twarock, Roman Tuma, Peter G. Stockley
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2227–2232. Published online 2015 Feb 2. doi: 10.1073/pnas.1420812112
PMCID:
PMC4343168
An HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence
TuAnh Ngoc Huynh, Shukun Luo, Daniel Pensinger, John-Demian Sauer, Liang Tong, Joshua J. Woodward
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E747–E756. Published online 2015 Jan 12. doi: 10.1073/pnas.1416485112
PMCID:
PMC4343097
Novel mixed-linkage β-glucan activated by c-di-GMP in Sinorhizobium meliloti
Daniel Pérez-Mendoza, Miguel Ángel Rodríguez-Carvajal, Lorena Romero-Jiménez, Gabriela de Araujo Farias, Javier Lloret, María Trinidad Gallegos, Juan Sanjuán
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E757–E765. Published online 2015 Feb 3. doi: 10.1073/pnas.1421748112
PMCID:
PMC4343143
Differential RNA-seq of Vibrio cholerae identifies the VqmR small RNA as a regulator of biofilm formation
Kai Papenfort, Konrad U. Förstner, Jian-Ping Cong, Cynthia M. Sharma, Bonnie L. Bassler
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E766–E775. Published online 2015 Feb 2. doi: 10.1073/pnas.1500203112
PMCID:
PMC4343088

Neuroscience

Self-affirmation alters the brain’s response to health messages and subsequent behavior change
Emily B. Falk, Matthew Brook O’Donnell, Christopher N. Cascio, Francis Tinney, Yoona Kang, Matthew D. Lieberman, Shelley E. Taylor, Lawrence An, Kenneth Resnicow, Victor J. Strecher
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1977–1982. Published online 2015 Feb 2. doi: 10.1073/pnas.1500247112
PMCID:
PMC4343089
Behavioral training reverses global cortical network dysfunction induced by perinatal antidepressant exposure
Xiaoming Zhou, Jordan Y.-F. Lu, Ryan D. Darling, Kimberly L. Simpson, Xiaoqing Zhu, Fang Wang, Liping Yu, Xinde Sun, Michael M. Merzenich, Rick C. S. Lin
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2233–2238. Published online 2015 Feb 2. doi: 10.1073/pnas.1416582111
PMCID:
PMC4343129
Yumei Cao, David Bartolomé-Martín, Naama Rotem, Carlos Rozas, Shlomo S. Dellal, Marcelo A. Chacon, Bashkim Kadriu, Maria Gulinello, Kamran Khodakhah, Donald S. Faber
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2239–2244. Published online 2015 Feb 2. doi: 10.1073/pnas.1405748112
PMCID:
PMC4343133
Keri J. Fogle, Lisa S. Baik, Jerry H. Houl, Tri T. Tran, Logan Roberts, Nicole A. Dahm, Yu Cao, Ming Zhou, Todd C. Holmes
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2245–2250. Published online 2015 Feb 2. doi: 10.1073/pnas.1416586112
PMCID:
PMC4343116
Vicky Ping Chen, Yang Gao, Liyi Geng, Robin J. Parks, Yuan-Ping Pang, Stephen Brimijoin
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2251–2256. Published online 2015 Feb 2. doi: 10.1073/pnas.1421536112
PMCID:
PMC4343161
Network-based metaanalysis identifies HNF4A and PTBP1 as longitudinally dynamic biomarkers for Parkinson’s disease
Jose A. Santiago, Judith A. Potashkin
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2257–2262. Published online 2015 Feb 2. doi: 10.1073/pnas.1423573112
PMCID:
PMC4343174
Two-photon brightness of azobenzene photoswitches designed for glutamate receptor optogenetics
Elizabeth C. Carroll, Shai Berlin, Joshua Levitz, Michael A. Kienzler, Zhe Yuan, Dorte Madsen, Delmar S. Larsen, Ehud Y. Isacoff
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E776–E785. Published online 2015 Feb 4. doi: 10.1073/pnas.1416942112
PMCID:
PMC4343171

Pharmacology

Regulator of G protein signaling 6 is a critical mediator of both reward-related behavioral and pathological responses to alcohol
Adele Stewart, Biswanath Maity, Simon P. Anderegg, Chantal Allamargot, Jianqi Yang, Rory A. Fisher
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E786–E795. Published online 2015 Feb 2. doi: 10.1073/pnas.1418795112
PMCID:
PMC4343156

Physiology

A fluid secretion pathway unmasked by acinar-specific Tmem16A gene ablation in the adult mouse salivary gland
Marcelo A. Catalán, Yusuke Kondo, Gaspar Peña-Munzenmayer, Yasna Jaramillo, Frances Liu, Sooji Choi, Edward Crandall, Zea Borok, Per Flodby, Gary E. Shull, James E. Melvin
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2263–2268. Published online 2015 Feb 2. doi: 10.1073/pnas.1415739112
PMCID:
PMC4343136
Potassium channelopathy-like defect underlies early-stage cerebrovascular dysfunction in a genetic model of small vessel disease
Fabrice Dabertrand, Christel Krøigaard, Adrian D. Bonev, Emmanuel Cognat, Thomas Dalsgaard, Valérie Domenga-Denier, David C. Hill-Eubanks, Joseph E. Brayden, Anne Joutel, Mark T. Nelson
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E796–E805. Published online 2015 Feb 2. doi: 10.1073/pnas.1420765112
PMCID:
PMC4343103

Plant Biology

A methyltransferase required for proper timing of the vernalization response in Arabidopsis
Joohyun Lee, Jae-Young Yun, Wei Zhao, Wen-Hui Shen, Richard M. Amasino
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2269–2274. Published online 2015 Jan 20. doi: 10.1073/pnas.1423585112
PMCID:
PMC4343098
Auxin binding protein 1 (ABP1) is not required for either auxin signaling or Arabidopsis development
Yangbin Gao, Yi Zhang, Da Zhang, Xinhua Dai, Mark Estelle, Yunde Zhao
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2275–2280. Published online 2015 Feb 2. doi: 10.1073/pnas.1500365112
PMCID:
PMC4343106
Siamsa M. Doyle, Ash Haeger, Thomas Vain, Adeline Rigal, Corrado Viotti, Małgorzata Łangowska, Qian Ma, Jiří Friml, Natasha V. Raikhel, Glenn R. Hicks, Stéphanie Robert
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E806–E815. Published online 2015 Feb 2. doi: 10.1073/pnas.1424856112
PMCID:
PMC4343110

Psychological and Cognitive Sciences

Role of the motor system in language knowledge
Iris Berent, Anna-Katharine Brem, Xu Zhao, Erica Seligson, Hong Pan, Jane Epstein, Emily Stern, Albert M. Galaburda, Alvaro Pascual-Leone
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 1983–1988. Published online 2015 Feb 2. doi: 10.1073/pnas.1416851112
PMCID:
PMC4343166

Sustainability Science

Rapid loss of lakes on the Mongolian Plateau
Shengli Tao, Jingyun Fang, Xia Zhao, Shuqing Zhao, Haihua Shen, Huifeng Hu, Zhiyao Tang, Zhiheng Wang, Qinghua Guo
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2281–2286. Published online 2015 Feb 2. doi: 10.1073/pnas.1411748112
PMCID:
PMC4343146

Systems Biology

A strategy for tissue self-organization that is robust to cellular heterogeneity and plasticity
Alec E. Cerchiari, James C. Garbe, Noel Y. Jee, Michael E. Todhunter, Kyle E. Broaders, Donna M. Peehl, Tejal A. Desai, Mark A. LaBarge, Matthew Thomson, Zev J. Gartner
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2287–2292. Published online 2015 Jan 29. doi: 10.1073/pnas.1410776112
PMCID:
PMC4343104
Highly multiplexed profiling of single-cell effector functions reveals deep functional heterogeneity in response to pathogenic ligands
Yao Lu, Qiong Xue, Markus R. Eisele, Endah S. Sulistijo, Kara Brower, Lin Han, El-ad David Amir, Dana Pe’er, Kathryn Miller-Jensen, Rong Fan
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E607–E615. Published online 2015 Feb 2. doi: 10.1073/pnas.1416756112
PMCID:
PMC4343126

Corrections

Correction for Das et al., Structure of CrgA, a cell division structural and regulatory protein from Mycobacterium tuberculosis, in lipid bilayers
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E816. Published online 2015 Jan 23. doi: 10.1073/pnas.1500959112
PMCID:
PMC4343150
Correction for Liu et al., Altered ubiquitin causes perturbed calcium homeostasis, hyperactivation of calpain, dysregulated differentiation, and cataract
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E817. Published online 2015 Jan 27. doi: 10.1073/pnas.1501368112
PMCID:
PMC4343118
Correction for Jeon et al., Human 3D vascularized organotypic microfluidic assays to study breast cancer cell extravasation
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): E818. Published online 2015 Feb 2. doi: 10.1073/pnas.1501426112
PMCID:
PMC4343157

Retraction


Articles from Proceedings of the National Academy of Sciences of the United States of America are provided here courtesy of National Academy of Sciences