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Volume 111(31);  August 5, 2014

Articles from this journal are usually available in PMC after a 6-month delay (embargo). Some articles may be available sooner.

This Week in PNAS

In This Issue
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11225–11226. Published online Aug 5, 2014. doi: 10.1073/iti3114111
PMCID:
PMC4128103

News Feature

Sarah C. P. Williams
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11227–11229. Published online Aug 5, 2014. doi: 10.1073/pnas.1413117111
PMCID:
PMC4128104

Commentaries

RABbing cancer the wrong way
Prashant K. Khade, Paraskevi Giannakakou
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11230–11231. Published online Jul 22, 2014. doi: 10.1073/pnas.1410788111
PMCID:
PMC4128146
Vapor-deposited glasses provide clearer view of two-level systems
M. D. Ediger
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11232–11233. Published online Jul 22, 2014. doi: 10.1073/pnas.1411278111
PMCID:
PMC4128156
Sequence specificity of human telomerase
Robert Alexander Wu, Kathleen Collins
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11234–11235. Published online Jul 23, 2014. doi: 10.1073/pnas.1411276111
PMCID:
PMC4128130

PNAS Plus Significance Statements

PNAS Plus Significance Statements
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11236–11237. Published online Aug 5, 2014. doi: 10.1073/pnas.ss11131
PMCID:
PMC4128126

PNAS Plus

Garvin A. Heath, Patrick O’Donoughue, Douglas J. Arent, Morgan Bazilian
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): E3167–E3176. Published online Jul 21, 2014. doi: 10.1073/pnas.1309334111
PMCID:
PMC4128108
Phosphatidylinositol 4,5-bisphosphate triggers activation of focal adhesion kinase by inducing clustering and conformational changes
Guillermina M. Goñi, Carolina Epifano, Jasminka Boskovic, Marta Camacho-Artacho, Jing Zhou, Agnieszka Bronowska, M. Teresa Martín, Michael J. Eck, Leonor Kremer, Frauke Gräter, Francesco Luigi Gervasio, Mirna Perez-Moreno, Daniel Lietha
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): E3177–E3186. Published online Jul 21, 2014. doi: 10.1073/pnas.1317022111
PMCID:
PMC4128148
Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G
Evangelos Papadopoulos, Simon Jenni, Eihab Kabha, Khuloud J. Takrouri, Tingfang Yi, Nicola Salvi, Rafael E. Luna, Evripidis Gavathiotis, Poornachandran Mahalingam, Haribabu Arthanari, Ricard Rodriguez-Mias, Revital Yefidoff-Freedman, Bertal H. Aktas, Michael Chorev, Jose A. Halperin, Gerhard Wagner
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): E3187–E3195. Published online Jul 21, 2014. doi: 10.1073/pnas.1410250111
PMCID:
PMC4128100
Side-chain conformation at the selectivity filter shapes the permeation free-energy landscape of an ion channel
Tyler J. Harpole, Claudio Grosman
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): E3196–E3205. Published online Jul 21, 2014. doi: 10.1073/pnas.1408950111
PMCID:
PMC4128128
Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages
Scott McComb, Erin Cessford, Norah A. Alturki, Julie Joseph, Bojan Shutinoski, Justyna B. Startek, Ana M. Gamero, Karen L. Mossman, Subash Sad
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): E3206–E3213. Published online Jul 21, 2014. doi: 10.1073/pnas.1407068111
PMCID:
PMC4128105
Pablo F. Céspedes, Susan M. Bueno, Bruno A. Ramírez, Roberto S. Gomez, Sebastián A. Riquelme, Christian E. Palavecino, Juan Pablo Mackern-Oberti, Jorge E. Mora, David Depoil, Catarina Sacristán, Michael Cammer, Alison Creneguy, Tuan H. Nguyen, Claudia A. Riedel, Michael L. Dustin, Alexis M. Kalergis
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): E3214–E3223. Published online Jul 23, 2014. doi: 10.1073/pnas.1400760111
PMCID:
PMC4128097
Toll-like receptor 9 signaling acts on multiple elements of the germinal center to enhance antibody responses
Derek C. Rookhuizen, Anthony L. DeFranco
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): E3224–E3233. Published online Jul 22, 2014. doi: 10.1073/pnas.1323985111
PMCID:
PMC4128120
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
Ting Wang, Daniele M. Gilkes, Naoharu Takano, Lisha Xiang, Weibo Luo, Corey J. Bishop, Pallavi Chaturvedi, Jordan J. Green, Gregg L. Semenza
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): E3234–E3242. Published online Jun 17, 2014. doi: 10.1073/pnas.1410041111
PMCID:
PMC4128139
Subpolar addition of new cell wall is directed by DivIVA in mycobacteria
Xavier Meniche, Renee Otten, M. Sloan Siegrist, Christina E. Baer, Kenan C. Murphy, Carolyn R. Bertozzi, Christopher M. Sassetti
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): E3243–E3251. Published online Jul 21, 2014. doi: 10.1073/pnas.1402158111
PMCID:
PMC4128124

Physical Sciences

Applied Mathematics

Predicting fruit fly’s sensing rate with insect flight simulations
Song Chang, Z. Jane Wang
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11246–11251. Published online Jul 21, 2014. doi: 10.1073/pnas.1314738111
PMCID:
PMC4128102

Applied Physical Sciences

Helical motion of the cell body enhances Caulobacter crescentus motility
Bin Liu, Marco Gulino, Michael Morse, Jay X. Tang, Thomas R. Powers, Kenneth S. Breuer
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11252–11256. Published online Jul 22, 2014. doi: 10.1073/pnas.1407636111
PMCID:
PMC4128131
Intravital imaging of cardiac function at the single-cell level
Aaron D. Aguirre, Claudio Vinegoni, Matt Sebas, Ralph Weissleder
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11257–11262. Published online Jul 22, 2014. doi: 10.1073/pnas.1401316111
PMCID:
PMC4128110

Earth, Atmospheric, and Planetary Sciences

Oceanographic dynamics and the end of the last interglacial in the subpolar North Atlantic
Zohra Mokeddem, Jerry F. McManus, Delia W. Oppo
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11263–11268. Published online Jul 21, 2014. doi: 10.1073/pnas.1322103111
PMCID:
PMC4128163

Engineering

Synthesis of bioactive protein hydrogels by genetically encoded SpyTag-SpyCatcher chemistry
Fei Sun, Wen-Bin Zhang, Alborz Mahdavi, Frances H. Arnold, David A. Tirrell
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11269–11274. Published online Jul 21, 2014. doi: 10.1073/pnas.1401291111
PMCID:
PMC4128157
Stationary nanoliter droplet array with a substrate of choice for single adherent/nonadherent cell incubation and analysis
Jonathan Shemesh, Tom Ben Arye, Jonathan Avesar, Joo H. Kang, Amir Fine, Michael Super, Amit Meller, Donald E. Ingber, Shulamit Levenberg
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11293–11298. Published online Jul 22, 2014. doi: 10.1073/pnas.1404472111
PMCID:
PMC4128147

Environmental Sciences

An obligately aerobic soil bacterium activates fermentative hydrogen production to survive reductive stress during hypoxia
Michael Berney, Chris Greening, Ralf Conrad, William R. Jacobs, Jr., Gregory M. Cook
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11479–11484. Published online Jul 21, 2014. doi: 10.1073/pnas.1407034111
PMCID:
PMC4128101
Sebastian Bubendorfer, Mihaly Koltai, Florian Rossmann, Victor Sourjik, Kai M. Thormann
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11485–11490. Published online Jul 21, 2014. doi: 10.1073/pnas.1405820111
PMCID:
PMC4128160

Physics

Vapor-deposited glasses provide clearer view of two-level systems
M. D. Ediger
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11232–11233. Published online Jul 22, 2014. doi: 10.1073/pnas.1411278111
PMCID:
PMC4128156
Suppression of tunneling two-level systems in ultrastable glasses of indomethacin
Tomás Pérez-Castañeda, Cristian Rodríguez-Tinoco, Javier Rodríguez-Viejo, Miguel A. Ramos
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11275–11280. Published online Jul 7, 2014. doi: 10.1073/pnas.1405545111
PMCID:
PMC4128158
Quantum nonlocality does not exist
Frank J. Tipler
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11281–11286. Published online Jul 11, 2014. doi: 10.1073/pnas.1324238111
PMCID:
PMC4128114

Sustainability Science

Garvin A. Heath, Patrick O’Donoughue, Douglas J. Arent, Morgan Bazilian
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): E3167–E3176. Published online Jul 21, 2014. doi: 10.1073/pnas.1309334111
PMCID:
PMC4128108

Social Sciences

Psychological and Cognitive Sciences

Patricia K. Kuhl, Rey R. Ramírez, Alexis Bosseler, Jo-Fu Lotus Lin, Toshiaki Imada
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11238–11245. Published online Jul 14, 2014. doi: 10.1073/pnas.1410963111
PMCID:
PMC4128155
A family-oriented psychosocial intervention reduces inflammation in low-SES African American youth
Gregory E. Miller, Gene H. Brody, Tianyi Yu, Edith Chen
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11287–11292. Published online Jul 21, 2014. doi: 10.1073/pnas.1406578111
PMCID:
PMC4128159

Biological Sciences

Applied Biological Sciences

Stationary nanoliter droplet array with a substrate of choice for single adherent/nonadherent cell incubation and analysis
Jonathan Shemesh, Tom Ben Arye, Jonathan Avesar, Joo H. Kang, Amir Fine, Michael Super, Amit Meller, Donald E. Ingber, Shulamit Levenberg
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11293–11298. Published online Jul 22, 2014. doi: 10.1073/pnas.1404472111
PMCID:
PMC4128147
Peng Xu, Lingyun Li, Fuming Zhang, Gregory Stephanopoulos, Mattheos Koffas
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11299–11304. Published online Jul 21, 2014. doi: 10.1073/pnas.1406401111
PMCID:
PMC4128127

Biochemistry

Sequence specificity of human telomerase
Robert Alexander Wu, Kathleen Collins
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11234–11235. Published online Jul 23, 2014. doi: 10.1073/pnas.1411276111
PMCID:
PMC4128130
Synthesis of bioactive protein hydrogels by genetically encoded SpyTag-SpyCatcher chemistry
Fei Sun, Wen-Bin Zhang, Alborz Mahdavi, Frances H. Arnold, David A. Tirrell
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11269–11274. Published online Jul 21, 2014. doi: 10.1073/pnas.1401291111
PMCID:
PMC4128157
John V. Bason, Martin G. Montgomery, Andrew G. W. Leslie, John E. Walker
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11305–11310. Published online Jul 21, 2014. doi: 10.1073/pnas.1411560111
PMCID:
PMC4128166
A self-regulating template in human telomerase
Andrew F. Brown, Joshua D. Podlevsky, Xiaodong Qi, Yinnan Chen, Mingyi Xie, Julian J.-L. Chen
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11311–11316. Published online Jun 30, 2014. doi: 10.1073/pnas.1402531111
PMCID:
PMC4128165
Impact of DNA3′pp5′G capping on repair reactions at DNA 3′ ends
Ushati Das, Mathieu Chauleau, Heather Ordonez, Stewart Shuman
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11317–11322. Published online Jul 21, 2014. doi: 10.1073/pnas.1409203111
PMCID:
PMC4128118
Method for identifying phosphorylated substrates of specific cyclin/cyclin-dependent kinase complexes
Yinyin Li, Frederick R. Cross, Brian T. Chait
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11323–11328. Published online Jul 21, 2014. doi: 10.1073/pnas.1409666111
PMCID:
PMC4128132
Encapsidated hepatitis B virus reverse transcriptase is poised on an ordered RNA lattice
Joseph Che-Yen Wang, David G. Nickens, Thomas B. Lentz, Daniel D. Loeb, Adam Zlotnick
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11329–11334. Published online Jul 17, 2014. doi: 10.1073/pnas.1321424111
PMCID:
PMC4128116
Residue level quantification of protein stability in living cells
William B. Monteith, Gary J. Pielak
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11335–11340. Published online Jul 21, 2014. doi: 10.1073/pnas.1406845111
PMCID:
PMC4128145
Lysine methylation-dependent binding of 53BP1 to the pRb tumor suppressor
Simon M. Carr, Shonagh Munro, Lykourgos-Panagiotis Zalmas, Oleg Fedorov, Catrine Johansson, Tobias Krojer, Cari A. Sagum, Mark T. Bedford, Udo Oppermann, Nicholas B. La Thangue
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11341–11346. Published online Jul 21, 2014. doi: 10.1073/pnas.1403737111
PMCID:
PMC4128150
Qianmin Wang, Alvaro H. Crevenna, Ines Kunze, Naoko Mizuno
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11347–11352. Published online Jul 24, 2014. doi: 10.1073/pnas.1403135111
PMCID:
PMC4128117
Phosphatidylinositol 4,5-bisphosphate triggers activation of focal adhesion kinase by inducing clustering and conformational changes
Guillermina M. Goñi, Carolina Epifano, Jasminka Boskovic, Marta Camacho-Artacho, Jing Zhou, Agnieszka Bronowska, M. Teresa Martín, Michael J. Eck, Leonor Kremer, Frauke Gräter, Francesco Luigi Gervasio, Mirna Perez-Moreno, Daniel Lietha
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): E3177–E3186. Published online Jul 21, 2014. doi: 10.1073/pnas.1317022111
PMCID:
PMC4128148
Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G
Evangelos Papadopoulos, Simon Jenni, Eihab Kabha, Khuloud J. Takrouri, Tingfang Yi, Nicola Salvi, Rafael E. Luna, Evripidis Gavathiotis, Poornachandran Mahalingam, Haribabu Arthanari, Ricard Rodriguez-Mias, Revital Yefidoff-Freedman, Bertal H. Aktas, Michael Chorev, Jose A. Halperin, Gerhard Wagner
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): E3187–E3195. Published online Jul 21, 2014. doi: 10.1073/pnas.1410250111
PMCID:
PMC4128100

Biophysics and Computational Biology

Predicting fruit fly’s sensing rate with insect flight simulations
Song Chang, Z. Jane Wang
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11246–11251. Published online Jul 21, 2014. doi: 10.1073/pnas.1314738111
PMCID:
PMC4128102
Helical motion of the cell body enhances Caulobacter crescentus motility
Bin Liu, Marco Gulino, Michael Morse, Jay X. Tang, Thomas R. Powers, Kenneth S. Breuer
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11252–11256. Published online Jul 22, 2014. doi: 10.1073/pnas.1407636111
PMCID:
PMC4128131
Modeling gating charge and voltage changes in response to charge separation in membrane proteins
Ilsoo Kim, Suman Chakrabarty, Peter Brzezinski, Arieh Warshel
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11353–11358. Published online Jul 21, 2014. doi: 10.1073/pnas.1411573111
PMCID:
PMC4128161
Sequence-resolved free energy profiles of stress-bearing vimentin intermediate filaments
Beatrice Ramm, Johannes Stigler, Michael Hinczewski, D. Thirumalai, Harald Herrmann, Günther Woehlke, Matthias Rief
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11359–11364. Published online Jul 21, 2014. doi: 10.1073/pnas.1403122111
PMCID:
PMC4128112
Side-chain conformation at the selectivity filter shapes the permeation free-energy landscape of an ion channel
Tyler J. Harpole, Claudio Grosman
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): E3196–E3205. Published online Jul 21, 2014. doi: 10.1073/pnas.1408950111
PMCID:
PMC4128128

Cell Biology

Blockade of oncogenic IκB kinase activity in diffuse large B-cell lymphoma by bromodomain and extraterminal domain protein inhibitors
Michele Ceribelli, Priscilla N. Kelly, Arthur L. Shaffer, George W. Wright, Wenming Xiao, Yibin Yang, Lesley A. Mathews Griner, Rajarshi Guha, Paul Shinn, Jonathan M. Keller, Dongbo Liu, Paresma R. Patel, Marc Ferrer, Shivangi Joshi, Sujata Nerle, Peter Sandy, Emmanuel Normant, Craig J. Thomas, Louis M. Staudt
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11365–11370. Published online Jul 21, 2014. doi: 10.1073/pnas.1411701111
PMCID:
PMC4128109
Devaraj Basavarajappa, Min Wan, Ana Lukic, Dieter Steinhilber, Bengt Samuelsson, Olof Rådmark
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11371–11376. Published online Jul 17, 2014. doi: 10.1073/pnas.1410983111
PMCID:
PMC4128154
Regulatory effects of SKAR in interferon α signaling and its role in the generation of type I IFN responses
Barbara Kroczynska, Swarna Mehrotra, Beata Majchrzak-Kita, Ahmet Dirim Arslan, Jessica K. Altman, Brady L. Stein, Brandon McMahon, Piotr Kozlowski, Philipp J. Kahle, Elizabeth A. Eklund, Eleanor N. Fish, Leonidas C. Platanias
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11377–11382. Published online Jul 21, 2014. doi: 10.1073/pnas.1405250111
PMCID:
PMC4128135

Developmental Biology

Control of axon–axon attraction by Semaphorin reverse signaling
Hsiao-Han Hsieh, Wen-Tzu Chang, Li Yu, Yong Rao
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11383–11388. Published online Jul 21, 2014. doi: 10.1073/pnas.1321433111
PMCID:
PMC4128134
Johannes Hartwig, Katsiaryna Tarbashevich, Jochen Seggewiß, Martin Stehling, Jan Bandemer, Cecilia Grimaldi, Azadeh Paksa, Theresa Groß-Thebing, Dana Meyen, Erez Raz
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11389–11394. Published online Jul 21, 2014. doi: 10.1073/pnas.1400043111
PMCID:
PMC4128164

Environmental Sciences

Metaproteomics reveals differential modes of metabolic coupling among ubiquitous oxygen minimum zone microbes
Alyse K. Hawley, Heather M. Brewer, Angela D. Norbeck, Ljiljana Paša-Tolić, Steven J. Hallam
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11395–11400. Published online Jul 22, 2014. doi: 10.1073/pnas.1322132111
PMCID:
PMC4128106

Evolution

Fast running restricts evolutionary change of the vertebral column in mammals
Frietson Galis, David R. Carrier, Joris van Alphen, Steven D. van der Mije, Tom J. M. Van Dooren, Johan A. J. Metz, Clara M. A. ten Broek
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11401–11406. Published online Jul 14, 2014. doi: 10.1073/pnas.1401392111
PMCID:
PMC4128151
Complete genome of a nonphotosynthetic cyanobacterium in a diatom reveals recent adaptations to an intracellular lifestyle
Takuro Nakayama, Ryoma Kamikawa, Goro Tanifuji, Yuichiro Kashiyama, Naohiko Ohkouchi, John M. Archibald, Yuji Inagaki
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11407–11412. Published online Jul 21, 2014. doi: 10.1073/pnas.1405222111
PMCID:
PMC4128115

Genetics

Single-particle tracking reveals that free ribosomal subunits are not excluded from the Escherichia coli nucleoid
Arash Sanamrad, Fredrik Persson, Ebba G. Lundius, David Fange, Arvid H. Gynnå, Johan Elf
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11413–11418. Published online Jul 23, 2014. doi: 10.1073/pnas.1411558111
PMCID:
PMC4128099

Immunology and Inflammation

Denervation protects limbs from inflammatory arthritis via an impact on the microvasculature
Lars Stangenberg, Dalia Burzyn, Bryce A. Binstadt, Ralph Weissleder, Umar Mahmood, Christophe Benoist, Diane Mathis
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11419–11424. Published online Jul 21, 2014. doi: 10.1073/pnas.1410854111
PMCID:
PMC4128122
Dick J. H. van den Boomen, Richard T. Timms, Guinevere L. Grice, Helen R. Stagg, Karsten Skødt, Gordon Dougan, James A. Nathan, Paul J. Lehner
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11425–11430. Published online Jul 16, 2014. doi: 10.1073/pnas.1409099111
PMCID:
PMC4128144
Adaptor protein DOK3 promotes plasma cell differentiation by regulating the expression of programmed cell death 1 ligands
Xijun Ou, Shengli Xu, Yan-Feng Li, Kong-Peng Lam
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11431–11436. Published online Jul 22, 2014. doi: 10.1073/pnas.1400539111
PMCID:
PMC4128136
Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages
Scott McComb, Erin Cessford, Norah A. Alturki, Julie Joseph, Bojan Shutinoski, Justyna B. Startek, Ana M. Gamero, Karen L. Mossman, Subash Sad
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): E3206–E3213. Published online Jul 21, 2014. doi: 10.1073/pnas.1407068111
PMCID:
PMC4128105
Pablo F. Céspedes, Susan M. Bueno, Bruno A. Ramírez, Roberto S. Gomez, Sebastián A. Riquelme, Christian E. Palavecino, Juan Pablo Mackern-Oberti, Jorge E. Mora, David Depoil, Catarina Sacristán, Michael Cammer, Alison Creneguy, Tuan H. Nguyen, Claudia A. Riedel, Michael L. Dustin, Alexis M. Kalergis
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): E3214–E3223. Published online Jul 23, 2014. doi: 10.1073/pnas.1400760111
PMCID:
PMC4128097
Toll-like receptor 9 signaling acts on multiple elements of the germinal center to enhance antibody responses
Derek C. Rookhuizen, Anthony L. DeFranco
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): E3224–E3233. Published online Jul 22, 2014. doi: 10.1073/pnas.1323985111
PMCID:
PMC4128120

Medical Sciences

RABbing cancer the wrong way
Prashant K. Khade, Paraskevi Giannakakou
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11230–11231. Published online Jul 22, 2014. doi: 10.1073/pnas.1410788111
PMCID:
PMC4128146
Comparative proteomic study reveals 17β-HSD13 as a pathogenic protein in nonalcoholic fatty liver disease
Wen Su, Yang Wang, Xiao Jia, Wenhan Wu, Linghai Li, Xiaodong Tian, Sha Li, Chunjiong Wang, Huamin Xu, Jiaqi Cao, Qifei Han, Shimeng Xu, Yong Chen, Yanfeng Zhong, Xiaoyan Zhang, Pingsheng Liu, Jan-Åke Gustafsson, Youfei Guan
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11437–11442. Published online Jul 15, 2014. doi: 10.1073/pnas.1410741111
PMCID:
PMC4128098
Transcriptional regulation of the sodium-coupled neutral amino acid transporter (SNAT2) by 17β-estradiol
Laura A. Velázquez-Villegas, Víctor Ortíz, Anders Ström, Nimbe Torres, David A. Engler, Risë Matsunami, David Ordaz-Rosado, Rocío García-Becerra, Adriana M. López-Barradas, Fernando Larrea, Jan-Åke Gustafsson, Armando R. Tovar
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11443–11448. Published online Jul 23, 2014. doi: 10.1073/pnas.1412099111
PMCID:
PMC4128162
Jonathan E. Zuckerman, Ismael Gritli, Anthony Tolcher, Jeremy D. Heidel, Dean Lim, Robert Morgan, Bartosz Chmielowski, Antoni Ribas, Mark E. Davis, Yun Yen
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11449–11454. Published online Jul 21, 2014. doi: 10.1073/pnas.1411393111
PMCID:
PMC4128111
Prolactin prevents hepatocellular carcinoma by restricting innate immune activation of c-Myc in mice
Hadley J. Hartwell, Keiko Y. Petrosky, James G. Fox, Nelson D. Horseman, Arlin B. Rogers
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11455–11460. Published online Jul 21, 2014. doi: 10.1073/pnas.1404267111
PMCID:
PMC4128121
RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection
Wenhui Hu, Rafal Kaminski, Fan Yang, Yonggang Zhang, Laura Cosentino, Fang Li, Biao Luo, David Alvarez-Carbonell, Yoelvis Garcia-Mesa, Jonathan Karn, Xianming Mo, Kamel Khalili
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11461–11466. Published online Jul 21, 2014. doi: 10.1073/pnas.1405186111
PMCID:
PMC4128125
PAPD5-mediated 3′ adenylation and subsequent degradation of miR-21 is disrupted in proliferative disease
Joost Boele, Helena Persson, Jay W. Shin, Yuri Ishizu, Inga S. Newie, Rolf Søkilde, Shannon M. Hawkins, Cristian Coarfa, Kazuhiro Ikeda, Ken-ichi Takayama, Kuniko Horie-Inoue, Yoshinari Ando, A. Maxwell Burroughs, Chihiro Sasaki, Chizuru Suzuki, Mizuho Sakai, Shintaro Aoki, Ayumi Ogawa, Akira Hasegawa, Marina Lizio, Kaoru Kaida, Bas Teusink, Piero Carninci, Harukazu Suzuki, Satoshi Inoue, Preethi H. Gunaratne, Carlos Rovira, Yoshihide Hayashizaki, Michiel J. L. de Hoon
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11467–11472. Published online Jul 21, 2014. doi: 10.1073/pnas.1317751111
PMCID:
PMC4128123
Peng-Chieh Chen, Jiani Yin, Hui-Wen Yu, Tao Yuan, Minerva Fernandez, Christina K. Yung, Quang M. Trinh, Vanya D. Peltekova, Jeffrey G. Reid, Erica Tworog-Dube, Margaret B. Morgan, Donna M. Muzny, Lincoln Stein, John D. McPherson, Amy E. Roberts, Richard A. Gibbs, Benjamin G. Neel, Raju Kucherlapati
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11473–11478. Published online Jul 21, 2014. doi: 10.1073/pnas.1324128111
PMCID:
PMC4128129
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
Ting Wang, Daniele M. Gilkes, Naoharu Takano, Lisha Xiang, Weibo Luo, Corey J. Bishop, Pallavi Chaturvedi, Jordan J. Green, Gregg L. Semenza
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): E3234–E3242. Published online Jun 17, 2014. doi: 10.1073/pnas.1410041111
PMCID:
PMC4128139

Microbiology

An obligately aerobic soil bacterium activates fermentative hydrogen production to survive reductive stress during hypoxia
Michael Berney, Chris Greening, Ralf Conrad, William R. Jacobs, Jr., Gregory M. Cook
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11479–11484. Published online Jul 21, 2014. doi: 10.1073/pnas.1407034111
PMCID:
PMC4128101
Sebastian Bubendorfer, Mihaly Koltai, Florian Rossmann, Victor Sourjik, Kai M. Thormann
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11485–11490. Published online Jul 21, 2014. doi: 10.1073/pnas.1405820111
PMCID:
PMC4128160
Evolutionary history of tuberculosis shaped by conserved mutations in the PhoPR virulence regulator
Jesús Gonzalo-Asensio, Wladimir Malaga, Alexandre Pawlik, Catherine Astarie-Dequeker, Charlotte Passemar, Flavie Moreau, Françoise Laval, Mamadou Daffé, Carlos Martin, Roland Brosch, Christophe Guilhot
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11491–11496. Published online Jul 21, 2014. doi: 10.1073/pnas.1406693111
PMCID:
PMC4128152
Energy conservation by oxidation of formate to carbon dioxide and hydrogen via a sodium ion current in a hyperthermophilic archaeon
Jae Kyu Lim, Florian Mayer, Sung Gyun Kang, Volker Müller
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11497–11502. Published online Jul 21, 2014. doi: 10.1073/pnas.1407056111
PMCID:
PMC4128143
A phage protein that inhibits the bacterial ATPase required for type IV pilus assembly
In-Young Chung, Hye-Jeong Jang, Hee-Won Bae, You-Hee Cho
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11503–11508. Published online Jul 21, 2014. doi: 10.1073/pnas.1403537111
PMCID:
PMC4128137
Genomics and host specialization of honey bee and bumble bee gut symbionts
Waldan K. Kwong, Philipp Engel, Hauke Koch, Nancy A. Moran
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11509–11514. Published online Jul 22, 2014. doi: 10.1073/pnas.1405838111
PMCID:
PMC4128107
Subpolar addition of new cell wall is directed by DivIVA in mycobacteria
Xavier Meniche, Renee Otten, M. Sloan Siegrist, Christina E. Baer, Kenan C. Murphy, Carolyn R. Bertozzi, Christopher M. Sassetti
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): E3243–E3251. Published online Jul 21, 2014. doi: 10.1073/pnas.1402158111
PMCID:
PMC4128124

Neuroscience

Patricia K. Kuhl, Rey R. Ramírez, Alexis Bosseler, Jo-Fu Lotus Lin, Toshiaki Imada
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11238–11245. Published online Jul 14, 2014. doi: 10.1073/pnas.1410963111
PMCID:
PMC4128155
Population of sensory neurons essential for asthmatic hyperreactivity of inflamed airways
Dimitri Tränkner, Nadeau Hahne, Ken Sugino, Mark A. Hoon, Charles Zuker
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11515–11520. Published online Jul 21, 2014. doi: 10.1073/pnas.1411032111
PMCID:
PMC4128113
Ataxia and Purkinje cell degeneration in mice lacking the CAMTA1 transcription factor
Chengzu Long, Chad E. Grueter, Kunhua Song, Song Qin, Xiaoxia Qi, Y. Megan Kong, John M. Shelton, James A. Richardson, Chun-Li Zhang, Rhonda Bassel-Duby, Eric N. Olson
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11521–11526. Published online Jul 21, 2014. doi: 10.1073/pnas.1411251111
PMCID:
PMC4128133
Satiety factor oleoylethanolamide recruits the brain histaminergic system to inhibit food intake
Gustavo Provensi, Roberto Coccurello, Hayato Umehara, Leonardo Munari, Giacomo Giacovazzo, Nicoletta Galeotti, Daniele Nosi, Silvana Gaetani, Adele Romano, Anna Moles, Patrizio Blandina, Maria Beatrice Passani
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11527–11532. Published online Jul 21, 2014. doi: 10.1073/pnas.1322016111
PMCID:
PMC4128140

Physiology

Intravital imaging of cardiac function at the single-cell level
Aaron D. Aguirre, Claudio Vinegoni, Matt Sebas, Ralph Weissleder
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11257–11262. Published online Jul 22, 2014. doi: 10.1073/pnas.1401316111
PMCID:
PMC4128110
Critical role of canonical transient receptor potential channel 7 in initiation of seizures
Kevin D. Phelan, U Thaung Shwe, Joel Abramowitz, Lutz Birnbaumer, Fang Zheng
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11533–11538. Published online Jul 21, 2014. doi: 10.1073/pnas.1411442111
PMCID:
PMC4128138

Plant Biology

Coordinated photomorphogenic UV-B signaling network captured by mathematical modeling
Xinhao Ouyang, Xi Huang, Xiao Jin, Zheng Chen, Panyu Yang, Hao Ge, Shigui Li, Xing Wang Deng
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11539–11544. Published online Jul 21, 2014. doi: 10.1073/pnas.1412050111
PMCID:
PMC4128142
Sulfenome mining in Arabidopsis thaliana
Cezary Waszczak, Salma Akter, Dominique Eeckhout, Geert Persiau, Khadija Wahni, Nandita Bodra, Inge Van Molle, Barbara De Smet, Didier Vertommen, Kris Gevaert, Geert De Jaeger, Marc Van Montagu, Joris Messens, Frank Van Breusegem
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11545–11550. Published online Jul 21, 2014. doi: 10.1073/pnas.1411607111
PMCID:
PMC4128149
Molecular genetic framework for protophloem formation
Antia Rodriguez-Villalon, Bojan Gujas, Yeon Hee Kang, Alice S. Breda, Pietro Cattaneo, Stephen Depuydt, Christian S. Hardtke
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11551–11556. Published online Jul 21, 2014. doi: 10.1073/pnas.1407337111
PMCID:
PMC4128119
Auxin transport sites are visualized in planta using fluorescent auxin analogs
Ken-ichiro Hayashi, Shouichi Nakamura, Shiho Fukunaga, Takeshi Nishimura, Mark K. Jenness, Angus S. Murphy, Hiroyasu Motose, Hiroshi Nozaki, Masahiko Furutani, Takashi Aoyama
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11557–11562. Published online Jul 21, 2014. doi: 10.1073/pnas.1408960111
PMCID:
PMC4128153
Carsten Rautengarten, Berit Ebert, Ignacio Moreno, Henry Temple, Thomas Herter, Bruce Link, Daniela Doñas-Cofré, Adrián Moreno, Susana Saéz-Aguayo, Francisca Blanco, Jennifer C. Mortimer, Alex Schultink, Wolf-Dieter Reiter, Paul Dupree, Markus Pauly, Joshua L. Heazlewood, Henrik V. Scheller, Ariel Orellana
Proc Natl Acad Sci U S A. Aug 5, 2014; 111(31): 11563–11568. Published online Jul 22, 2014. doi: 10.1073/pnas.1406073111
PMCID:
PMC4128141

Articles from Proceedings of the National Academy of Sciences of the United States of America are provided here courtesy of National Academy of Sciences