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Comment Fame is a bubble, but not for some Gregory A Petsko PMCID: PMC522860 Opinion Predicting and validating microRNA targets Eric C Lai PMCID: PMC522861 Minireviews What's in a centromere? Jonathan C Lamb, James Theuri, and James A Birchler PMCID: PMC522862 Chemical genomics in yeast Charles Brenner PMCID: PMC522863 Protein Family Review The cyclooxygenases NV Chandrasekharan and Daniel L Simmons PMCID: PMC522864 Meeting Reports RNAi for research and therapy Michael A Goldman PMCID: PMC522865 Structural genomics and structural biology: compare and contrast John-Marc Chandonia, Thomas N Earnest, and Steven E Brenner PMCID: PMC522866 Celebrating 40 years of biochemistry in Europe Errol C Friedberg and Tomas Lindahl PMCID: PMC522867 Method Improving identification of differentially expressed genes in microarray studies using information from public databases Richard D Kim and Peter J Park PMCID: PMC522877 A catalog of human cDNA expression clones and its application to structural genomics Konrad Büssow, Claudia Quedenau, Volker Sievert, Janett Tischer, Christoph Scheich, Harald Seitz, Brigitte Hieke, Frank H Niesen, Frank Götz, Ulrich Harttig, and Hans Lehrach PMCID: PMC522878 Large-scale exploration of growth inhibition caused by overexpression of genomic fragments in Saccharomyces cerevisiae Jeanne Boyer, Gwenaël Badis, Cécile Fairhead, Emmanuel Talla, Florence Hantraye, Emmanuelle Fabre, Gilles Fischer, Christophe Hennequin, Romain Koszul, Ingrid Lafontaine, Odile Ozier-Kalogeropoulos, Miria Ricchetti, Guy-Franck Richard, Agnès Thierry, and Bernard Dujon PMCID: PMC522879 Research Computational identification of developmental enhancers: conservation and function of transcription factor binding-site clusters in Drosophila melanogaster and Drosophila pseudoobscura Benjamin P Berman, Barret D Pfeiffer, Todd R Laverty, Steven L Salzberg, Gerald M Rubin, Michael B Eisen, and Susan E Celniker PMCID: PMC522868 Global nucleosome occupancy in yeast Bradley E Bernstein, Chih Long Liu, Emily L Humphrey, Ethan O Perlstein, and Stuart L Schreiber PMCID: PMC522869 A first-draft human protein-interaction map Ben Lehner and Andrew G Fraser PMCID: PMC522870 Comprehensive analysis of pseudogenes in prokaryotes: widespread gene decay and failure of putative horizontally transferred genes Yang Liu, Paul M Harrison, Victor Kunin, and Mark Gerstein PMCID: PMC522871 Prediction and identification of Arabidopsis thaliana microRNAs and their mRNA targets Xiu-Jie Wang, José L Reyes, Nam-Hai Chua, and Terry Gaasterland PMCID: PMC522872 Discovery of estrogen receptor α target genes and response elements in breast tumor cells Chin-Yo Lin, Anders Ström, Vinsensius Berlian Vega, Say Li Kong, Ai Li Yeo, Jane S Thomsen, Wan Ching Chan, Balraj Doray, Dhinoth K Bangarusamy, Adaikalavan Ramasamy, Liza A Vergara, Suisheng Tang, Allen Chong, Vladimir B Bajic, Lance D Miller, Jan-Åke Gustafsson, and Edison T Liu PMCID: PMC522873 An Ambystoma mexicanum EST sequencing project: analysis of 17,352 expressed sequence tags from embryonic and regenerating blastema cDNA libraries Bianca Habermann, Anne-Gaelle Bebin, Stephan Herklotz, Michael Volkmer, Kay Eckelt, Kerstin Pehlke, Hans Henning Epperlein, Hans Konrad Schackert, Glenis Wiebe, and Elly M Tanaka PMCID: PMC522874 Microarray analysis of microRNA expression in the developing mammalian brain Eric A Miska, Ezequiel Alvarez-Saavedra, Matthew Townsend, Akira Yoshii, Nenad Šestan, Pasko Rakic, Martha Constantine-Paton, and H Robert Horvitz PMCID: PMC522875 Function-informed transcriptome analysis of Drosophila renal tubule Jing Wang, Laura Kean, Jingli Yang, Adrian K Allan, Shireen A Davies, Pawel Herzyk, and Julian AT Dow PMCID: PMC522876
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