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Villous atrophy with crypt hyperplasia in malignant histiocytosis of the nose. This article has been cited by other articles in PMC.Abstract Intestinal changes, mainly in the jejunum, were investigated in 13 cases of malignant histiocytosis at necropsy and who had presented as lethal midline granuloma. Villous atrophy with crypt hyperplasia was observed in all cases, and a proliferation of atypical histiocytes was observed in seven cases. In the remaining cases, histiocytes with normal morphology increased in number. These findings showed that a prolonged abnormal proliferation of histiocytes was present in the small intestine of these cases concurrently with the nasal lesions. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.7M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References. Images in this article Selected References These references are in PubMed. This may not be the complete list of references from this article.
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