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Genomic-scale measurement of mRNA turnover and the mechanisms of action of the anti-cancer drug flavopiridol
Lloyd T Lam, Oxana K Pickeral, Amy C Peng, Andreas Rosenwald, Elaine M Hurt, Jena M Giltnane, Lauren M Averett, Hong Zhao, R Eric Davis, Mohan Sathyamoorthy, Larry M Wahl, Eric D Harris, Judy A Mikovits, Anne P Monks, Melinda G Hollingshead, Edward A Sausville, Louis M Staudt
Genome Biol. 2001; 2(10): research0041.1–research0041.11. Published online 2001 September 13.
PMCID:
PMC57796
Abstract Full Text PDF–415K Supplementary Material
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 Is Cited by the Following 31 Articles in this Archive:
Unstable Transcripts in Arabidopsis Allotetraploids Are Associated with Nonadditive Gene Expression in Response to Abiotic and Biotic Stresses
Eun-Deok Kim, Z. Jeffery Chen
PLoS One. 2011; 6(8): e24251. Published online 2011 August 29. doi: 10.1371/journal.pone.0024251
PMCID:
PMC3163679
Abstract Full Text PDF–2.0M Supplementary Material
Multiple platform assessment of the EGF dependent transcriptome by microarray and deep tag sequencing analysis
Franc Llorens, Manuela Hummel, Xavier Pastor, Anna Ferrer, Raquel Pluvinet, Ana Vivancos, Ester Castillo, Susana Iraola, Ana M Mosquera, Eva González, Juanjo Lozano, Matthew Ingham, Juliane C Dohm, Marc Noguera, Robert Kofler, Jose Antonio del Río, Mònica Bayés, Heinz Himmelbauer, Lauro Sumoy
BMC Genomics. 2011; 12: 326. Published online 2011 June 23. doi: 10.1186/1471-2164-12-326
PMCID:
PMC3141672
Abstract Full Text PDF–2.5M Supplementary Material
Global impact of RNA polymerase II elongation inhibition on alternative splicing regulation
Joanna Y. Ip, Dominic Schmidt, Qun Pan, Arun K. Ramani, Andrew G. Fraser, Duncan T. Odom, Benjamin J. Blencowe
Genome Res. 2011 March; 21(3): 390–401. doi: 10.1101/gr.111070.110
PMCID:
PMC3044853
Abstract Full Text PDF–1.5M
Dynamic transcriptome analysis measures rates of mRNA synthesis and decay in yeast
Christian Miller, Björn Schwalb, Kerstin Maier, Daniel Schulz, Sebastian Dümcke, Benedikt Zacher, Andreas Mayer, Jasmin Sydow, Lisa Marcinowski, Lars Dölken, Dietmar E Martin, Achim Tresch, Patrick Cramer
Mol Syst Biol. 2011; 7: 458. Published online 2011 January 4. doi: 10.1038/msb.2010.112
PMCID:
PMC3049410
Abstract Full Text PDF–3.5M Supplementary Material
Genome-wide analysis of mRNA decay patterns during early Drosophila development
Stefan Thomsen, Simon Anders, Sarath Chandra Janga, Wolfgang Huber, Claudio R Alonso
Genome Biol. 2010; 11(9): R93. Published online 2010 September 21. doi: 10.1186/gb-2010-11-9-r93
PMCID:
PMC2965385
Abstract Full Text PDF–4.1M Supplementary Material
mRNA Degradation Plays a Significant Role in the Program of Gene Expression Regulated by Phosphatidylinositol 3-Kinase Signaling
Julie R. Graham, Melissa C. Hendershott, Jolyon Terragni, Geoffrey M. Cooper
Mol Cell Biol. 2010 November; 30(22): 5295–5305. Published online 2010 September 20. doi: 10.1128/MCB.00303-10
PMCID:
PMC2976374
Abstract Full Text PDF–589K Supplementary Material
MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia
Sara C. Monroe, Stephanie Y. Jo, Daniel S. Sanders, Venkatesha Basrur, Kojo S. Elenitoba-Johnson, Robert K. Slany, Jay L. Hess
Exp Hematol. Author manuscript; available in PMC 2012 January 1.
Published in final edited form as: Exp Hematol. 2011 January; 39(1): 77–86.e1-5. Published online 2010 September 18. doi: 10.1016/j.exphem.2010.09.003
PMCID:
PMC3038424
Abstract Full Text PDF–755K Supplementary Material
mRNA degradation controls differentiation state-dependent differences in transcript and splice variant abundance
Peter A. C. 't Hoen, Michael Hirsch, Emile J. de Meijer, Renée X. de Menezes, Gert Jan van Ommen, Johan T. den Dunnen
Nucleic Acids Res. 2011 January; 39(2): 556–566. Published online 2010 September 17. doi: 10.1093/nar/gkq790
PMCID:
PMC3025562
Abstract Full Text PDF–581K Supplementary Material
Phase I clinical and pharmacokinetic study of a novel schedule of flavopiridol in relapsed or refractory acute leukemias
William Blum, Mitch A. Phelps, Rebecca B. Klisovic, Darlene M. Rozewski, Wenjun Ni, Katie A. Albanese, Brad Rovin, Cheryl Kefauver, Steven M. Devine, David M. Lucas, Amy Johnson, Larry J. Schaaf, John C. Byrd, Guido Marcucci, Michael R. Grever
Haematologica. 2010 July; 95(7): 1098–1105. Published online 2010 May 11. doi: 10.3324/haematol.2009.017103
PMCID:
PMC2895033
Abstract Full Text PDF–524K
Halogenated imidazole derivatives block RNA polymerase II elongation along mitogen inducible genes
Michal Mikula, Karolina Hanusek, Agnieszka Paziewska, Artur Dzwonek, Tymon Rubel, Karol Bomsztyk, Jerzy Ostrowski
BMC Mol Biol. 2010; 11: 4. Published online 2010 January 15. doi: 10.1186/1471-2199-11-4
PMCID:
PMC2824761
Abstract Full Text PDF–1.1M Supplementary Material
IL-3 and Oncogenic Abl Regulate the Myeloblast Transcriptome by Altering mRNA Stability
Jason Ernst, Louis Ghanem, Ziv Bar-Joseph, Michael McNamara, Jason Brown, Richard A. Steinman
PLoS One. 2009; 4(10): e7469. Published online 2009 October 15. doi: 10.1371/journal.pone.0007469
PMCID:
PMC2758590
Abstract Full Text PDF–429K Supplementary Material
Coordinated posttranscriptional mRNA population dynamics during T-cell activation
Neelanjan Mukherjee, Patrick J Lager, Matthew B Friedersdorf, Marshall A Thompson, Jack D Keene
Mol Syst Biol. 2009; 5: 288. Published online 2009 July 28. doi: 10.1038/msb.2009.44
PMCID:
PMC2724974
Abstract Full Text PDF–1.6M Supplementary Material
Clinical response and pharmacokinetics from a phase 1 study of an active dosing schedule of flavopiridol in relapsed chronic lymphocytic leukemia
Mitch A. Phelps, Thomas S. Lin, Amy J. Johnson, Eunju Hurh, Darlene M. Rozewski, Katherine L. Farley, Di Wu, Kristie A. Blum, Beth Fischer, Sarah M. Mitchell, Mollie E. Moran, Michelle Brooker-McEldowney, Nyla A. Heerema, David Jarjoura, Larry J. Schaaf, John C. Byrd, Michael R. Grever, James T. Dalton
Blood. 2009 March 19; 113(12): 2637–2645. Prepublished online 2008 November 3. doi: 10.1182/blood-2008-07-168583
PMCID:
PMC2661854
Abstract Full Text
Compensatory IKKα activation of classical NF-κB signaling during IKKβ inhibition identified by an RNA interference sensitization screen
Lloyd T. Lam, R. Eric Davis, Vu N. Ngo, Georg Lenz, George Wright, Weihong Xu, Hong Zhao, Xin Yu, Lenny Dang, Louis M. Staudt
Proc Natl Acad Sci U S A. 2008 December 30; 105(52): 20798–20803. Published online 2008 December 22. doi: 10.1073/pnas.0806491106
PMCID:
PMC2634958
Abstract Full Text PDF–468K Supplementary Material
Database for mRNA Half-Life of 19 977 Genes Obtained by DNA Microarray Analysis of Pluripotent and Differentiating Mouse Embryonic Stem Cells
Lioudmila V. Sharova, Alexei A. Sharov, Timur Nedorezov, Yulan Piao, Nabeebi Shaik, Minoru S.H. Ko
DNA Res. 2009 February; 16(1): 45–58. Published online 2008 November 11. doi: 10.1093/dnares/dsn030
PMCID:
PMC2644350
Abstract Full Text PDF–549K Supplementary Material
Cyclin T1-Dependent Genes in Activated CD4+ T and Macrophage Cell Lines Appear Enriched in HIV-1 Co-Factors
Wendong Yu, Rajesh Ramakrishnan, Yan Wang, Karen Chiang, Tzu-Ling Sung, Andrew P. Rice
PLoS ONE. 2008; 3(9): e3146. Published online 2008 September 5. doi: 10.1371/journal.pone.0003146
PMCID:
PMC2519787
Abstract Full Text PDF–461K Supplementary Material
Combinatorial anti-leukemic disruption of oxidative homeostasis and mitochondrial stability by the redox reactive thalidomide CPS49 and flavopiridol
Yun Ge, Jung S. Byun, Paola De Luca, Geraldine Gueron, Idalia Yabe, Sara G. Sadiq-Ali, William D. Figg, Jesse Quintero, Cynthia M. Haggerty, Quentin Q. Li, Adriana De Siervi, Kevin Gardner
Mol Pharmacol. Author manuscript; available in PMC 2009 November 18.
Published in final edited form as: Mol Pharmacol. 2008 September; 74(3): 872–883. Published online 2008 June 12. doi: 10.1124/mol.107.040808
PMCID:
PMC2778846
Abstract Full Text PDF–3.3M
Targeting MET transcription as a therapeutic strategy in multiple myeloma
Cornel J. Phillip, Christine M. Stellrecht, Ramadevi Nimmanapalli, Varsha Gandhi
Cancer Chemother Pharmacol. Author manuscript; available in PMC 2010 June 28.
Published in final edited form as: Cancer Chemother Pharmacol. 2009 March; 63(4): 587–597. Published online 2008 May 29. doi: 10.1007/s00280-008-0770-2
PMCID:
PMC2892885
Abstract Full Text PDF–599K Supplementary Material
CIRCADIAN CLOCK ASSOCIATED1 Transcript Stability and the Entrainment of the Circadian Clock in Arabidopsis
Esther Yakir, Dror Hilman, Miriam Hassidim, Rachel M. Green
Plant Physiol. 2007 November; 145(3): 925–932. doi: 10.1104/pp.107.103812
PMCID:
PMC2048808
Abstract Full Text PDF–306K Supplementary Material
Direct inhibition of CDK9 blocks HIV-1 replication without preventing T cell activation in primary human peripheral blood lymphocytes
Dominic Salerno, Muneer G. Hasham, Renée Marshall, Judit Garriga, Alexander Y. Tsygankov, Xavier Graña
Gene. Author manuscript; available in PMC 2008 December 15.
Published in final edited form as: Gene. 2007 December 15; 405(1-2): 65–78. Published online 2007 September 19. doi: 10.1016/j.gene.2007.09.010
PMCID:
PMC2222555
Abstract Full Text PDF–734K
Whole-genome analysis of mRNA decay in Plasmodium falciparum reveals a global lengthening of mRNA half-life during the intra-erythrocytic development cycle
Jennifer L Shock, Kael F Fischer, Joseph L DeRisi
Genome Biol. 2007; 8(7): R134. Published online 2007 August 7. doi: 10.1186/gb-2007-8-7-r134
PMCID:
PMC2323219
Abstract Full Text PDF–495K Supplementary Material
Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells
Stéphane Larochelle, Karl A. Merrick, Marie-Emilie Terret, Lara Wohlbold, Nora M. Barboza, Chao Zhang, Kevan M. Shokat, Prasad V. Jallepalli, Robert P. Fisher
Mol Cell. Author manuscript; available in PMC 2008 March 23.
Published in final edited form as: Mol Cell. 2007 March 23; 25(6): 839–850. doi: 10.1016/j.molcel.2007.02.003
PMCID:
PMC1858677
Abstract Full Text PDF–821K Supplementary Material
Cross platform microarray analysis for robust identification of differentially expressed genes
Roberta Bosotti, Giuseppe Locatelli, Sandra Healy, Emanuela Scacheri, Luca Sartori, Ciro Mercurio, Raffaele Calogero, Antonella Isacchi
BMC Bioinformatics. 2007; 8(Suppl 1): S5. Published online 2007 March 8. doi: 10.1186/1471-2105-8-S1-S5
PMCID:
PMC1885857
Abstract Full Text PDF–1.1M Supplementary Material
Synthesis and biologic properties of hydrophilic sapphyrins, a new class of tumor-selective inhibitors of gene expression
Zhong Wang, Philip S Lecane, Patricia Thiemann, Qing Fan, Cecilia Cortez, Xuan Ma, Danielle Tonev, Dale Miles, Louie Naumovski, Richard A Miller, Darren Magda, Dong-Gyu Cho, Jonathan L Sessler, Brian L Pike, Samantha M Yeligar, Mazen W Karaman, Joseph G Hacia
Mol Cancer. 2007; 6: 9. Published online 2007 January 19. doi: 10.1186/1476-4598-6-9
PMCID:
PMC1784109
Abstract Full Text PDF–501K Supplementary Material
Developmental regulators containing the I-mfa domain interact with T cyclins and Tat and modulate transcription
Qi Wang, Tara M. Young, Michael B. Mathews, Tsafi Pe’ery
J Mol Biol. Author manuscript; available in PMC 2007 May 14.
Published in final edited form as: J Mol Biol. 2007 March 30; 367(3): 630–646. Published online 2007 January 12. doi: 10.1016/j.jmb.2007.01.020
PMCID:
PMC1868487
Abstract Full Text PDF–2.1M
Transcriptional upregulation of p57 (Kip2) by the cyclin dependent kinase inhibitor BMS-387032 is E2F dependent and serves as a negative feedback loop limiting cytotoxicity
Yihong Ma, W. Douglas Cress
Oncogene. Author manuscript; available in PMC 2007 December 10.
Published in final edited form as: Oncogene. 2007 May 24; 26(24): 3532–3540. Published online 2006 December 18. doi: 10.1038/sj.onc.1210143
PMCID:
PMC2128050
Abstract Full Text PDF–1.5M
Induction of the HIV-1 Tat co-factor cyclin T1 during monocyte differentiation is required for the regulated expression of a large portion of cellular mRNAs
Wendong Yu, Yan Wang, Chad A Shaw, Xiao-Feng Qin, Andrew P Rice
Retrovirology. 2006; 3: 32. Published online 2006 June 9. doi: 10.1186/1742-4690-3-32
PMCID:
PMC1557533
Abstract Full Text PDF–1.4M
Profiling condition-specific, genome-wide regulation of mRNA stability in yeast
Barrett C. Foat, S. Sean Houshmandi, Wendy M. Olivas, Harmen J. Bussemaker
Proc Natl Acad Sci U S A. 2005 December 6; 102(49): 17675–17680. Published online 2005 November 29. doi: 10.1073/pnas.0503803102
PMCID:
PMC1295595
Abstract Full Text PDF–514K Supplementary Material
Transcription inhibition by flavopiridol: mechanism of chronic lymphocytic leukemia cell death
Rong Chen, Michael J. Keating, Varsha Gandhi, William Plunkett
Blood. 2005 October 1; 106(7): 2513–2519. Prepublished online 2005 June 21. doi: 10.1182/blood-2005-04-1678
PMCID:
PMC1895272
Abstract Full Text
Genome-wide analysis of mRNA decay in resting and activated primary human T lymphocytes
Arvind Raghavan, Rachel L. Ogilvie, Cavan Reilly, Michelle L. Abelson, Shalini Raghavan, Jayprakash Vasdewani, Mitchell Krathwohl, Paul R. Bohjanen
Nucleic Acids Res. 2002 December 15; 30(24): 5529–5538.
PMCID:
PMC140061
Abstract Full Text PDF–170K Supplementary Material
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