• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of iaiPermissionsJournals.ASM.orgJournalIAI ArticleJournal InfoAuthorsReviewers
Infect Immun. Nov 1980; 30(2): 547–553.
PMCID: PMC551346

Duck influenza lacking evidence of disease signs and immune response.

Abstract

Influenza viruses A/duck/Hokkaido/5/77 (Hav7N2), A/budgerigar/Hokkaido/1/77 (Hav4Nav1), A/Kumamoto/22/76 (H3N2), A/Aichi/2/68 (H3N2), and A/New Jersey/8/76 (Hsw1N1) were experimentally inoculated into Pekin ducks. Of these, the influenza viruses of duck and budgerigar origin replicated in the intestinal tract of the ducks. The infected ducks shed the virus in the feces to high titers, but did not show clinical signs of disease and scarcely produced detectable serum antibodies. Using immunofluorescent staining, we demonstrated that the target cells of the duck virus in ducks were the simple columnar epithelial cells which form crypts in the large intestines, especially in the colon. After primary infection, the birds resisted reinfection with the duck virus at least for 28 days, but from 46 days onward they were susceptible to reinfection. These infections were quickly restricted by a brisk secondary immune response, reflected in the rapid appearance of high titers of antibody after reinoculation. In contrat to the avian influenza viruses, the remaining three influenza viruses of human origin did not replicate in the intestinal tract but did cause a serum antibody response.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.0M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Images in this article

Click on the image to see a larger version.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Bahl AK, Pomeroy BS, Mangundimedjo S, Easterday BC. Isolation of type A influenza and Newcastle disease viruses from migratory waterfowl in the Mississippi flyway. J Am Vet Med Assoc. 1977 Nov 1;171(9):949–951. [PubMed]
  • Downie JC, Hinshaw V, Laver WG. The ecology of influenza. Isolation of type 'A' influenza viruses from Australian pelagic birds. Aust J Exp Biol Med Sci. 1977 Dec;55(6):635–643. [PubMed]
  • Gresíková M, Tůmová B, Stumpa A, Sekeyová M. Isolation of influenza virus from wild ducks (Anas platyrhynchos). Acta Virol. 1978 Jul;22(4):296–301. [PubMed]
  • Hinshaw VS, Webster RG, Rodriguez RJ. Influenza A viruses: combinations of hemagglutinin and neuraminidase subtypes isolated from animals and other sources. Brief review. Arch Virol. 1979;62(4):281–290. [PubMed]
  • Kawano J, Yanagawa R, Kida H. Site of replication of influenza virus A/budgerigar/Hokkaido/1/77 (Hav 4 Nav 1) in budgerigars. Zentralbl Bakteriol Orig A. 1979 Oct;245(1-2):1–7. [PubMed]
  • Kida H, Yanagawa R. Isolation and characterization of influenza a viruses from wild free-flying ducks in Hokkaido, Japan. Zentralbl Bakteriol Orig A. 1979 Jul;244(2-3):135–143. [PubMed]
  • Matsuoka Y, Kida H, Yanagowa R. Isolation of an influenza virus subtype Hav4Navl from a budgerigar. Microbiol Immunol. 1979;23(1):35–38. [PubMed]
  • Rosenberger JK, Krauss WC, Slemons RD. Isolation of Newcastle disease and type-A influenza viruses from migratory waterfowl in the Atlantic flyway. Avian Dis. 1974 Oct-Dec;18(4):610–613. [PubMed]
  • SEVER JL. Application of a microtechnique to viral serological investigations. J Immunol. 1962 Mar;88:320–329. [PubMed]
  • Shortridge KF, Butterfield WK, Webster RG, Campbell CH. Isolation and characterization of influenza A viruses from avian species in Hong Kong. Bull World Health Organ. 1977;55(1):15–20. [PMC free article] [PubMed]
  • Slemons RD, Easterday BC. Virus replication in the digestive tract of ducks exposed by aerosol to type-A influenza. Avian Dis. 1978 Jul-Sep;22(3):367–377. [PubMed]
  • Slemons RD, Johnson DC, Osborn JS, Hayes F. Type-A influenza viruses isolated from wild free-flying ducks in California. Avian Dis. 1974 Jan-Mar;18(1):119–124. [PubMed]
  • Webster RG, Morita M, Pridgen C, Tumova B. Ortho- and paramyxoviruses from migrating feral ducks: characterization of a new group of influenza A viruses. J Gen Virol. 1976 Aug;32(2):217–225. [PubMed]
  • Webster RG, Yakhno M, Hinshaw VS, Bean WJ, Murti KG. Intestinal influenza: replication and characterization of influenza viruses in ducks. Virology. 1978 Feb;84(2):268–278. [PubMed]

Articles from Infection and Immunity are provided here courtesy of American Society for Microbiology (ASM)

Formats:

Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...

Links

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...