Logo of jvirolPermissionsJournals.ASM.orgJournalJV ArticleJournal InfoAuthorsReviewers
J Virol. 1977 Sep; 23(3): 811–815.
PMCID: PMC515892

Correlation of virus polypeptide structure with attenuation of poliovirus type 1.


Several avirulent samples of poliovirus type 1 derived in the process attenuating the neurovirulent Mahoney strain show an altered virus capsid polypeptide, VP-1, on polyacrylamide gel electrophoresis of sodium dodecyl sulfate-disrupted virions.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (638K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Images in this article

Click on the image to see a larger version.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Beckman LD, Caliguiri LA, Lilly LS. Cleavage site alterations in poliovirus-specific precursor proteins. Virology. 1976 Aug;73(1):216–227. [PubMed]
  • HOLLAND JJ, McLAREN LC. Improved method for staining cell monolayers for virus plaque counts. J Bacteriol. 1959 Oct;78:596–597. [PMC free article] [PubMed]
  • Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 1970 Aug 15;227(5259):680–685. [PubMed]
  • LI CP, SCHAEFFER M. Isolation of a non-neurotropic variant of type I poliomyelitis virus. Proc Soc Exp Biol Med. 1954 Oct;87(1):148–153. [PubMed]
  • Phillips BA, Fennell R. Polypeptide composition of poliovirions, naturally occurring empty capsids, and 14S precursor particles. J Virol. 1973 Aug;12(2):291–299. [PMC free article] [PubMed]
  • Tattersall P, Cawte PJ, Shatkin AJ, Ward DC. Three structural polypeptides coded for by minite virus of mice, a parvovirus. J Virol. 1976 Oct;20(1):273–289. [PMC free article] [PubMed]

Articles from Journal of Virology are provided here courtesy of American Society for Microbiology (ASM)


Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...


  • MedGen
    Related information in MedGen
  • PubMed
    PubMed citations for these articles
  • Substance
    PubChem Substance links

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...