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J Clin Pathol. Jan 1995; 48(1): 84–85.
PMCID: PMC502270

Gastrointestinal haemorrhage from a jejunal gangliocytic paraganglioma.


A case of jejunal gangliocytic paraganglioma is reported in a 54 year old woman who presented with brisk melaena. The tumour was not encapsulated, involved the mucosa and submucosa, and was composed of epithelial nests, spindle cells, and ganglion cells. These cells were mixed, giving carcinoid-like, paraganglioma-like, and ganglioneuroma-like patterns in different areas of the tumour. The lesion was excised locally and recovery was uneventful. Only four previous cases have been reported at this site.

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Selected References

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  • Rice JM. Fetal susceptibility to viral and chemical carcinogens. Lab Invest. 1988 Jan;58(1):1–4. [PubMed]
  • Reed RJ, Caroca PJ, Jr, Harkin JC. Gangliocytic paraganglioma. Am J Surg Pathol. 1977 Sep;1(3):207–216. [PubMed]
  • Grouls V, Pickartz H, Reis HE. Gestieltes polypöses gangliozytisches Paragangliom der zuführenden Jejunumschlinge eines Billroth-II-Magens. Leber Magen Darm. 1987 Oct;17(5):327–333. [PubMed]

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