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Logo of jclinpathJournal of Clinical PathologyCurrent TOCInstructions for authors
J Clin Pathol. Jan 1995; 48(1): 59–60.
PMCID: PMC502264

Pathologist variation in reporting cervical borderline epithelial abnormalities and cervical intraepithelial neoplasia.

Abstract

AIMS--To evaluate the interobserver variation in the diagnosis of cervical intraepithelial lesions, including the new category "borderline abnormalities of uncertain significance" (BAUS) which has not been tested before. METHODS--Biopsy specimens of 122 patients were reviewed by five histopathologists and the diagnoses subjected to kappa statistical analysis. RESULTS--There was poor interobserver agreement in all categories, particularly between BAUS and normal tissue. CONCLUSIONS--The current guidelines for the histological diagnosis of cervical intraepithelial neoplasia and BAUS are poorly reproducible.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Ismail SM, Colclough AB, Dinnen JS, Eakins D, Evans DM, Gradwell E, O'Sullivan JP, Summerell JM, Newcombe RG. Observer variation in histopathological diagnosis and grading of cervical intraepithelial neoplasia. BMJ. 1989 Mar 18;298(6675):707–710. [PMC free article] [PubMed]
  • Robertson AJ, Anderson JM, Beck JS, Burnett RA, Howatson SR, Lee FD, Lessells AM, McLaren KM, Moss SM, Simpson JG, et al. Observer variability in histopathological reporting of cervical biopsy specimens. J Clin Pathol. 1989 Mar;42(3):231–238. [PMC free article] [PubMed]
  • Buckley CH, Butler EB, Fox H. Cervical intraepithelial neoplasia. J Clin Pathol. 1982 Jan;35(1):1–13. [PMC free article] [PubMed]

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