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J Clin Pathol. 1983 June; 36(6): 670–673. | PMCID: PMC498348 |
Phenomenon of resistance to Augmentin associated with sensitivity to ampicillin: occurrence and explanation. W Brumfitt, J M Hamilton-Miller, S Dixson, R A Gargan, and A Gooding Abstract Ampicillin was found to be some tenfold more active than amoxycillin against Enterobacter cloacae. This finding explains the observation that some Ent cloacae strains are sensitive to ampicillin in the disc test but resistant to Augmentin. Ampicillin was also found to be more active than amoxycillin against Citrobacter freundii and Serratia marcescens. In view of these findings, the practice of using ampicillin discs to predict sensitivity to amoxycillin should be reconsidered. The use of both ampicillin and amoxycillin discs is appropriate if errors are to be avoided. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (733K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References. Images in this article Click on the image to see a larger version. These references are in PubMed. This may not be the complete list of references from this article. - Sutherland R, Croydon EA, Rolinson GN. Amoxycillin: a new semi-synthetic penicillin. Br Med J. 1972 Jul 1;3(5817):13–16. [PubMed]
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