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J Clin Pathol. Apr 1991; 44(4): 346–348.
PMCID: PMC496919

Strongyloides stercoralis hyperinfection in an HIV positive patient.


A 25 year old British man of previous good health presented with persistent generalised lymphadenopathy and was found to be human immunodeficiency virus (HIV) antibody positive. Three years later after weight loss and loose stools Strongyloides stercoralis was identified in the latter and successfully treated with thiabendazole. Shortly afterwards, a further episode again responded rapidly, but was swiftly followed by a final and fatal illness with severe debility and metabolic imbalance unresponsive to all treatment. Necropsy showed widespread and heavy strongyloidiasis with pulmonary haemorrhage, bronchopneumonia, and meningitis.

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Selected References

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  • Armignacco O, Capecchi A, De Mori P, Grillo LR. Strongyloides stercoralis hyperinfection and the acquired immunodeficiency syndrome. Am J Med. 1989 Feb;86(2):258–258. [PubMed]
  • Sprott V, Selby CD, Ispahani P, Toghill PJ. Indigenous strongyloidiasis in Nottingham. Br Med J (Clin Res Ed) 1987 Mar 21;294(6574):741–742. [PMC free article] [PubMed]
  • Petithory JC, Derouin F. AIDS and strongyloidiasis in Africa. Lancet. 1987 Apr 18;1(8538):921–921. [PubMed]
  • Hakim SZ, Genta RM. Fatal disseminated strongyloidiasis in a Vietnam War veteran. Arch Pathol Lab Med. 1986 Sep;110(9):809–812. [PubMed]

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