• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of jnnpsycJournal of Neurology, Neurosurgery and PsychiatryCurrent TOCInstructions for authors
J Neurol Neurosurg Psychiatry. Mar 1979; 42(3): 256–265.
PMCID: PMC490730

Mental aspects of temporal lobe epilepsy. Follow-up of 74 patients after resection of a temporal lobe.

Abstract

Psychiatric disorders were investigated in 74 patients with drug-resistant temporal lobe epilepsy (complex partial epilepsy). In all cases unilateral anterior temporal lobectomy had been performed during the period 1960-69. At follow-up in 1970-71, 45 patients were free from seizures, and in a further group of 15 patients seizure frequency had been substantially reduced. There were four postoperative deaths. Six patients were psychiatrically normal and had no history of any such disorder. Behavioural disturbances were observed in 55 patients. Before operation 11 patients displayed schizophrenia-like psychoses, and nine others became psychotic during follow-up. Fourteen patients attempted suicide on one or more occasions. Half the patients had diminished sexual drive. Improvement in psychiatric status was clearly correlated with relief from seizures and, in those cases with only a few or no seizures after operation, led directly to social rehabilitation. The presence or absence of a psychiatric disorder was not useful as a criterion for or against surgery.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.3M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Blumer D, Walker AE. Sexual behavior in temporal lobe epilepsy. A study of the effects of temporal lobectomy on sexual behavior. Arch Neurol. 1967 Jan;16(1):37–43. [PubMed]
  • CAVANAGH JB. On certain small tumours encountered in the temporal lobe. Brain. 1958 Sep;81(3):389–405. [PubMed]
  • CAVANAGH JB, MEYER A. Aetiological aspects of Ammon's horn sclerosis associated with temporal lobe epilepsy. Br Med J. 1956 Dec 15;2(5006):1403–1407. [PMC free article] [PubMed]
  • Falconer MA. The surgical treatment of temporal lobe epilepsy. Neurochirurgia (Stuttg) 1965 Sep;8(5):161–172. [PubMed]
  • Falconer MA. The significance of mesial temporal sclerosis (Ammon's horn sclerosis) in epilepsy. Guys Hosp Rep. 1968;117(1):1–12. [PubMed]
  • Falconer MA. The pathological substrate of temporal lobe epilepsy. Guys Hosp Rep. 1970;119(1):47–60. [PubMed]
  • Falconer MA. Mesial temporal (Ammon's horn) sclerosis as a common cause of epilepsy. Aetiology, treatment, and prevention. Lancet. 1974 Sep 28;2(7883):767–770. [PubMed]
  • FALCONER MA, CAVANAGH JB. Clinico-pathological considerations of temporal lobe epilepsy due to small focal lesions. A study of cases submitted to operation. Brain. 1959 Dec;82:483–504. [PubMed]
  • FALCONER MA, MEYER A, HILL D, MITCHELL W, POND DA. Treatment of temporal-lobe epilepsy by temporal lobectomy; a survey of findings and results. Lancet. 1955 Apr 23;268(6869):827–835. [PubMed]
  • FALCONER MA, SERAFETINIDES EA, CORSELLIS JA. ETIOLOGY AND PATHOGENESIS OF TEMPORAL LOBE EPILEPSY. Arch Neurol. 1964 Mar;10:233–248. [PubMed]
  • GREEN JR, DUISBERG REH, McGRATH WB. Focal epilepsy of psychomotor type; a preliminary report of observations on effect of surgical therapy. J Neurosurg. 1951 Mar;8(2):157–172. [PubMed]
  • JAMES IP. Temporal lobectomy for psychomotor epilepsy. J Ment Sci. 1960 Apr;106:543–558. [PubMed]
  • Jensen I. Temporal lobe epilepsy. Etiological factors and surgical results. Acta Neurol Scand. 1976 Feb;53(2):103–118. [PubMed]
  • Jensen I. Temporal lobe epilepsy: types of seizures, age, and surgical results. Acta Neurol Scand. 1976 May;53(5):335–357. [PubMed]
  • Jensen I. Temporal lobe epilepsy. With special reference to surgical results, neuropathology, and social conditions. Dan Med Bull. 1977 Dec;24(6):235–251. [PubMed]
  • Jensen I, Klinken L. Temporal lobe epilepsy and neuropathology. Histological findings in resected temporal lobes correlated to surgical results and clinical aspects. Acta Neurol Scand. 1976 Nov;54(5):391–414. [PubMed]
  • Jensen I, Seedorff HH. Temporal lobe epilepsy and neuro-ophthalmology. Ophthalmological findings in 74 temporal lobe resected patients. Acta Ophthalmol (Copenh) 1976 Dec;54(6):827–841. [PubMed]
  • Jensen I, Vaernet K. Temporal lobe epilepsy. Follow-up investigation of 74 temporal lobe resected patients. Acta Neurochir (Wien) 1977;37(3-4):173–200. [PubMed]
  • SANO K, MALAMUD N. Clinical significance of sclerosis of the cornu ammonis: ictal psychic phenomena. AMA Arch Neurol Psychiatry. 1953 Jul;70(1):40–53. [PubMed]
  • Serafetinides EA. Psychosocial aspects of neurosurgical management of epilepsy. Adv Neurol. 1975;8:323–331. [PubMed]
  • Taylor DC. Mental state and temporal lobe epilepsy. A correlative account of 100 patients treated surgically. Epilepsia. 1972 Dec;13(6):727–765. [PubMed]
  • Taylor DC, Falconer MA. Clinical, socio-economic, and psychological changes after temporal lobectomy for epilepsy. Br J Psychiatry. 1968 Oct;114(515):1247–1261. [PubMed]
  • Van Buren JM, Ajmone-Marsan C, Mutsuga N, Sadowsky D. Surgery of temporal lobe epilepsy. Adv Neurol. 1975;8:155–196. [PubMed]

Articles from Journal of Neurology, Neurosurgery, and Psychiatry are provided here courtesy of BMJ Group

Formats:

Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...

Links

  • MedGen
    MedGen
    Related information in MedGen
  • PubMed
    PubMed
    PubMed citations for these articles

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...