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J Neurol Neurosurg Psychiatry. 1996 December; 61(6): 632–635. | PMCID: PMC486662 |
Spinal cord MRI in multiple sclerosis with multicoil arrays: a comparison between fast spin echo and fast FLAIR. M Filippi, T A Yousry, H Alkadhi, M Stehling, M A Horsfield, and R Voltz Department of Neurology, Scientific Institute Ospedale San Raffaele, University of Milan, Italy. Abstract OBJECTIVES: To compare the sensitivity of fast spin echo (FSE) and of fast fluid attenuated inversion recovery (fast FLAIR) in detecting spinal cord lesions in multiple sclerosis. METHODS: With a 1.5 Tesla machine and a multicoil receiver array, FSE images (with two different pixel sizes) and fast FLAIR images of the spinal cord were obtained from 13 patients with multiple sclerosis. RESULTS: Twenty three lesions (10 cervical, 12 thoracic, and one lumbar) were found in seven patients (54%) using FSE with the larger pixel size. Seventeen lesions (seven cervical and 10 thoracic) were detected in the same seven patients using FSE with smaller pixel size. Nine lesions (five cervical and four thoracic) were found using fast FLAIR in six patients (46%). All the lesions found using fast FLAIR were detected using the other two techniques and all the lesions detected by FSE with smaller pixel size were detected using FSE and greater pixel size. CONCLUSION: Fast FLAIR sequences detect substantially fewer cord lesions in patients with multiple sclerosis. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.1M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References. Images in this article Click on the image to see a larger version. These references are in PubMed. This may not be the complete list of references from this article. - Kidd D, Thorpe JW, Thompson AJ, Kendall BE, Moseley IF, MacManus DG, McDonald WI, Miller DH. Spinal cord MRI using multi-array coils and fast spin echo. II. Findings in multiple sclerosis. Neurology. 1993 Dec;43(12):2632–2637. [PubMed]
- Thorpe JW, Kidd D, Kendall BE, Tofts PS, Barker GJ, Thompson AJ, MacManus DG, McDonald WI, Miller DH. Spinal cord MRI using multi-array coils and fast spin echo. I. Technical aspects and findings in healthy adults. Neurology. 1993 Dec;43(12):2625–2631. [PubMed]
- Rydberg JN, Hammond CA, Grimm RC, Erickson BJ, Jack CR, Jr, Huston J, 3rd, Riederer SJ. Initial clinical experience in MR imaging of the brain with a fast fluid-attenuated inversion-recovery pulse sequence. Radiology. 1994 Oct;193(1):173–180. [PubMed]
- Hashemi RH, Bradley WG, Jr, Chen DY, Jordan JE, Queralt JA, Cheng AE, Henrie JN. Suspected multiple sclerosis: MR imaging with a thin-section fast FLAIR pulse sequence. Radiology. 1995 Aug;196(2):505–510. [PubMed]
- Filippi M, Yousry T, Baratti C, Horsfield MA, Mammi S, Becker C, Voltz R, Spuler S, Campi A, Reiser MF, Comi G. Quantitative assessment of MRI lesion load in multiple sclerosis. A comparison of conventional spin-echo with fast fluid-attenuated inversion recovery. Brain. 1996 Aug;119 (:1349–1355. [PubMed]
- Thomas DJ, Pennock JM, Hajnal JV, Young IR, Bydder GM, Steiner RE. Magnetic resonance imaging of spinal cord in multiple sclerosis by fluid-attenuated inversion recovery. Lancet. 1993 Mar 6;341(8845):593–594. [PubMed]
- White SJ, Hajnal JV, Young IR, Bydder GM. Use of fluid-attenuated inversion-recovery pulse sequences for imaging the spinal cord. Magn Reson Med. 1992 Nov;28(1):153–162. [PubMed]
- Poser CM, Paty DW, Scheinberg L, McDonald WI, Davis FA, Ebers GC, Johnson KP, Sibley WA, Silberberg DH, Tourtellotte WW. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol. 1983 Mar;13(3):227–231. [PubMed]
- Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology. 1983 Nov;33(11):1444–1452. [PubMed]
- Filippi M, Horsfield MA, Tofts PS, Barkhof F, Thompson AJ, Miller DH. Quantitative assessment of MRI lesion load in monitoring the evolution of multiple sclerosis. Brain. 1995 Dec;118 (:1601–1612. [PubMed]
- Finelli DA, Hurst GC, Karaman BA, Simon JE, Duerk JL, Bellon EM. Use of magnetization transfer for improved contrast on gradient-echo MR images of the cervical spine. Radiology. 1994 Oct;193(1):165–171. [PubMed]
- Constable RT, Gore JC. The loss of small objects in variable TE imaging: implications for FSE, RARE, and EPI. Magn Reson Med. 1992 Nov;28(1):9–24. [PubMed]
- Rydberg JN, Riederer SJ, Rydberg CH, Jack CR. Contrast optimization of fluid-attenuated inversion recovery (FLAIR) imaging. Magn Reson Med. 1995 Dec;34(6):868–877. [PubMed]
- Ho PS, Yu SW, Czervionke LF, Sether LA, Wagner M, Pech P, Haughton VM. MR appearance of gray and white matter at the cervicomedullary region. AJNR Am J Neuroradiol. 1989 Sep–Oct;10(5):1051–1055. [PubMed]
- Baratti C, Barkhof F, Hoogenraad F, Valk J. Partially saturated fluid attenuated inversion recovery (FLAIR) sequences in multiple sclerosis: comparison with fully relaxed FLAIR and conventional spin-echo. Magn Reson Imaging. 1995;13(4):513–521. [PubMed]
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