• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of brheartjLink to Publisher's site
Br Heart J. Aug 1985; 54(2): 179–183.
PMCID: PMC481875

Prevalence and clinical significance of aortic valve prolapse.

Abstract

The prevalence and clinical significance of aortic valve prolapse were determined prospectively in 2000 consecutive patients undergoing routine clinical cross sectional echocardiography. Two hundred and twelve patients were excluded because the aortic cusps were not adequately visualised. Aortic valve prolapse was defined as downward displacement of cuspal material below a line joining the points of attachment of the aortic valve leaflets. Twenty four cases of aortic valve prolapse (1.2%) were identified. The patients were aged 12-64 years and nine were women. All had underlying valvar heart disease and the commonest lesion (in 11 cases) was prolapse of the larger cusp in bicuspid valves. Aortic valve prolapse was seen in four patients with mitral valve prolapse (two with severe regurgitation), one of whom had marfanoid aortic root dilatation. The remaining examples of aortic prolapse were seen in patients with various disorders including one with pulmonary atresia, two with aortic root disease (one with dissection and one with idiopathic dilatation), and one case of severe mitral regurgitation. Valves destroyed by infective endocarditis were seen in two cases. Aortic valve prolapse may be detected in various cardiac disorders and does not imply the presence of aortic regurgitation, but when bicuspid aortic valves are present it may well be important in producing such regurgitation. Although aortic valve prolapse may be associated with severe forms of mitral valve prolapse, these patients rarely have aortic regurgitation.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.4M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Images in this article

Click on the image to see a larger version.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Carter JB, Sethi S, Lee GB, Edwards JE. Prolapse of semilunar cusps as causes of aortic insufficiency. Circulation. 1971 Jun;43(6):922–932. [PubMed]
  • Roberts WC, Morrow AG, McIntosh CL, Jones M, Epstein SE. Congenitally bicuspid aortic valve causing severe, pure aortic regurgitation without superimposed infective endocarditis. Analysis of 13 patients requiring aortic valve replacement. Am J Cardiol. 1981 Feb;47(2):206–209. [PubMed]
  • Read RC, Thal AP, Wendt VE. Symptomatic valvular myxomatous transformation (the floppy valve syndrome). A possible forme fruste of the Marfan syndrome. Circulation. 1965 Dec;32(6):897–910. [PubMed]
  • Morganroth J, Jones RH, Chen CC, Naito M. Two dimensional echocardiography in mitral, aortic and tricuspid valve prolapse. The clinical problem, cardiac nuclear imaging considerations and a proposed standard for diagnosis. Am J Cardiol. 1980 Dec 18;46(7):1164–1177. [PubMed]
  • Rodger JC, Morley P. Abnormal aortic valve echoes in mitral prolapse. Echocardiographic features of floppy aortic valve. Br Heart J. 1982 Apr;47(4):337–343. [PMC free article] [PubMed]
  • Becher H, Hanrath P, Bleifeld W, Bleese N. Correlation of echocardiographic and surgical findings in acute bacterial endocarditis. Eur Heart J. 1984 Oct;5 (Suppl 100):67–70. [PubMed]
  • Perloff JK. Evolving concepts of mitral-valve prolapse. N Engl J Med. 1982 Aug 5;307(6):369–370. [PubMed]
  • Stewart WJ, King ME, Gillam LD, Guyer DE, Weyman AE. Prevalence of aortic valve prolapse with bicuspid aortic valve and its relation to aortic regurgitation: a cross-sectional echocardiographic study. Am J Cardiol. 1984 Dec 1;54(10):1277–1282. [PubMed]
  • Leech G, Mills P, Leatham A. The diagnosis of a non-stenotic bicuspid aortic valve. Br Heart J. 1978 Sep;40(9):941–950. [PMC free article] [PubMed]
  • Fenoglio JJ, Jr, McAllister HA, Jr, DeCastro CM, Davia JE, Cheitlin MD. Congenital bicuspid aortic valve after age 20. Am J Cardiol. 1977 Feb;39(2):164–169. [PubMed]
  • Sahn DJ, Allen HD, Goldberg SJ, Friedman WF. Mitral valve prolapse in children: a problem defined by real-time cross-sectional echocardiography. Circulation. 1976 Apr;53(4):651–657. [PubMed]
  • Ogawa S, Hayashi J, Sasaki H, Tani M, Akaishi M, Mitamura H, Sano M, Hoshino T, Handa S, Nakamura Y. Evaluation of combined valvular prolapse syndrome by two-dimensional echocardiography. Circulation. 1982 Jan;65(1):174–180. [PubMed]
  • Rippe JM, Angoff G, Sloss LJ, Wynne J, Alpert JS. Multiple floppy valves: an echocardiographic syndrome. Am J Med. 1979 May;66(5):817–824. [PubMed]

Articles from British Heart Journal are provided here courtesy of BMJ Group

Formats:

Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...

Links

  • MedGen
    MedGen
    Related information in MedGen
  • PubMed
    PubMed
    PubMed citations for these articles

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...