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Journal List > J Clin Pathol > v.13(3); May 1960

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J Clin Pathol. 1960 May; 13(3): 246–248.
PMCID: PMC480060
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THE DETERMINATION OF SERUM IRON AFTER THE INTRAVENOUS INJECTION OF IRON-DEXTRAN
D. Webster
Department of Medicine and Geriatric Medicine, the General Hospital, Sunderland
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Abstract
A rapid technique for the determination of iron in serum, after the intravenous injection of iron-dextran, is presented.
Dithionite is used for the reduction of ferric to ferrous iron.
The use of a detergent solution enables protein precipitation to be omitted.
The iron reagent, 4: 7-diphenyl-1: 10-phenanthroline, and its ferrous complex are both soluble in the dilute detergent solution.
Lipaemic serum can be used without affecting the results.
The recovery of added ferric iron, as iron-dextran, is quantitative.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
  • MACKENZIE A, TINDLE J. Determination of plasma-volume using intravenous iron dextran. Lancet. 1959 Feb 14;1(7068):333–335. [PubMed]
  • TRINDER P. The improved determination of iron in serum. J Clin Pathol. 1956 May;9(2):170–172. [PubMed]
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