• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of jclinpathJournal of Clinical PathologyCurrent TOCInstructions for authors
J Clin Pathol. May 1971; 24(4): 348–353.
PMCID: PMC476989

The pathology of parietal pleural plaques

Abstract

The incidence, morbid anatomy, histology, and relationship of hyaline pleural plaques to exposure to asbestos has been studied.

Plaques were found in 12·3% of 334 hospital necropsies (in an urban population in Glasgow, 41 cases). In 85·3% (35 cases) asbestos bodies were found in the lungs. There is evidence of a dose-response relationship between the number of asbestos bodies found in the lungs and the presence of pleural plaques.

The selective distribution of plaques within the pleural cavities suggests that mechanical factors play a part in their localization.

Histological examination contributed little to understanding the mechanism of plaque formation; that asbestos bodies have been detected in only a few cases suggest that their presence in the parietal pleura is not essential to plaque formation. The suggested mechanisms of plaque formation are discussed.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.4M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Images in this article

Click on the image to see a larger version.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Anjilvel L, Thurlbeck WM. The incidence of asbestos bodies in the lungs at random necropsies in Montreal. Can Med Assoc J. 1966 Dec 3;95(23):1179–1182. [PMC free article] [PubMed]
  • Anton HC. Multiple pleural plaques. Br J Radiol. 1967 Sep;40(477):685–690. [PubMed]
  • Anton HC. Multiple pleural plaques. II. Br J Radiol. 1968 May;41(485):341–348. [PubMed]
  • Ashcroft T. Asbestos bodies in routine necropsies on Tyneside: a pathological and social study. Br Med J. 1968 Mar 9;1(5592):614–618. [PMC free article] [PubMed]
  • CAUNA D, TOTTEN RS, GROSS P. ASBESTOS BODIES IN HUMAN LUNGS AT AUTOPSY. JAMA. 1965 May 3;192:371–373. [PubMed]
  • GILLMAN T, PENN J, BRONKS D, ROUX M. Abnormal elastic fibers; appearance in cutaneous carcinoma, irradiation injuries, and arterial and other degenerative connective tissue lesions in man. AMA Arch Pathol. 1955 Jun;59(6):733–749. [PubMed]
  • Hourihane DO, Lessof L, Richardson PC. Hyaline and calcified pleural plaques as an index of exposure to asbestos. Br Med J. 1966 Apr 30;1(5495):1069–1074. [PMC free article] [PubMed]
  • Hourihane DO, McCaughey WT. Pathological aspects of asbestosis. Postgrad Med J. 1966 Oct;42(492):613–622. [PMC free article] [PubMed]
  • LAWSON JP. PLEURAL CALCIFICATION AS A SIGN OF ASBESTOSIS; A REPORT OF THREE CASES. Clin Radiol. 1963 Oct;14:414–417. [PubMed]
  • Roberts GH. Asbestos bodies in lungs at necropsy. J Clin Pathol. 1967 Jul;20(4):570–573. [PMC free article] [PubMed]
  • Thomson JG, Graves WM., Jr Asbestos as an urban air contaminant. Arch Pathol. 1966 May;81(5):458–464. [PubMed]
  • THOMSON JG, KASCHULA RO, MACDONALD RR. Asbestos as a modern urban hazard. S Afr Med J. 1963 Jan 19;37:77–81. [PubMed]
  • WYERS H. Asbestosis. Postgrad Med J. 1949 Dec;25(290):631–illust. [PMC free article] [PubMed]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Group

Formats:

Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...

Links

  • MedGen
    MedGen
    Related information in MedGen
  • PubMed
    PubMed
    PubMed citations for these articles
  • Substance
    Substance
    PubChem Substance links

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...