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J Clin Pathol. 1975 July; 28(7): 531–539. | PMCID: PMC475765 |
Extraction of serum vitamin B12 for radio-isotopic and Lactobacillus leichmannii assay. J L Raven and M B Robson Abstract The protein precipitates discarded during the extraction process of the Lactobacillus leichmannii vitamin B12 assay have been shown to contain significant amounts of vitamin B12. This loss of vitamin B12 provide a satisfactory explanation for many of the descrepancies between the serum vitamin B12 values obtained by the L. leichmannii method and the radio-isotopic method of Raven et al (1969). It is possible to produce lower results by the method of Raven et al (1969)by incorporating into that method the L. leichmannii extraction process; it is also possible to produce higher results by the L. leichmannii method using a papain extraction process. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.3M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References. Images in this article Click on the image to see a larger version. These references are in PubMed. This may not be the complete list of references from this article. - Ardeman S, Chanarin I, Krafchik B, Singer W. Addisonian pernicious anaemia and intrinsic factor antibodies in thyroid disorders. Q J Med. 1966 Jul;35(139):421–431. [PubMed]
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