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Antimicrob Agents Chemother. 1974 October; 6(4): 411–414. | PMCID: PMC444661 |
Activity of Tetracycline, Doxycycline, and Minocycline Against Methicillin-Susceptible and -Resistant Staphylococci J. N. Minuth, T. M. Holmes, and D. M. Musher Department of Medicine, Veterans Administration Hospital, Houston, Texas 77031 Baylor College of Medicine, Houston, Texas 77025 Abstract Tetracycline, doxycycline, and minocycline were evaluated for their antibacterial activity against methicillin-susceptible and -resistant isolates of Staphylococcus. At clinically achievable levels both doxycycline and minocycline were more active than tetracycline against methicillin-susceptible organisms. Tetracycline and doxycycline had no activity against methicillin-resistant staphylococci, whereas minocycline at 2 μg/ml inhibited six of 13 strains and, at 3 μg/ml, 10 of 13 strains. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (488K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References. These references are in PubMed. This may not be the complete list of references from this article. - Bach MC, Zinner SH, Wilcox C, Finland M. Efficacy of standard disc-diffusion test as applied to susceptibility of Staphylococcus aureus to tetracycline and minocycline. J Lab Clin Med. 1972 Feb;79(2):316–325. [PubMed]
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