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Proc Natl Acad Sci U S A. Dec 1973; 70(12 Pt 1-2): 3321–3323.
PMCID: PMC427228

Analysis of Gene Diversity in Subdivided Populations

Abstract

A method is presented by which the gene diversity (heterozygosity) of a subdivided population can be analyzed into its components, i.e., the gene diversities within and between subpopulations. This method is applicable to any population without regard to the number of alleles per locus, the pattern of evolutionary forces such as mutation, selection, and migration, and the reproductive method of the organism used. Measures of the absolute and relative magnitudes of gene differentiation among subpopulations are also proposed.

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Selected References

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  • Wright S. Isolation by Distance. Genetics. 1943 Mar;28(2):114–138. [PMC free article] [PubMed]
  • Nei M, Roychoudhury AK. Gene differences between Caucasian, Negro, and Japanese populations. Science. 1972 Aug 4;177(4047):434–436. [PubMed]

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