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Infect Immun. Mar 1976; 13(3): 998–1000.
PMCID: PMC420707

Inhibition of lethality in endotoxin-challenged mice treated with zinc chloride.

Abstract

Zinc chloride protected against lethality in mice undergoing endotoxin shock.

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Selected References

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  • Chvapil M. New aspects in the biological role of zinc: a stabilizer of macromolecules and biological membranes. Life Sci. 1973 Oct 16;13(8):1041–1049. [PubMed]
  • Filkins JP. Hepatic lysosomes and the inactivation of endotoxin. J Reticuloendothel Soc. 1971 May;9(5):480–490. [PubMed]
  • GELLER P, MERRILL ER, JAWETZ E. Effects of cortisone and antibiotics on lethal action of endotoxins in mice. Proc Soc Exp Biol Med. 1954 Aug-Sep;86(4):716–719. [PubMed]
  • Ignarro LJ, Slywka J, Krassikoff N. Inhibition of lysosomal enzyme release by catecholamines: possible mediation by cyclic 3',5'-adenosine monophosphate. Life Sci I. 1971 Nov 15;10(22):1309–1315. [PubMed]
  • JANOFF A, WEISSMANN G, ZWEIOFACH BW, THOMAS L. Pathogenesis of experimental shock. IV. Studies on lysosomes in normal and tolerant animals subjected to lethal trauma and endotoxemia. J Exp Med. 1962 Oct 1;116:451–466. [PMC free article] [PubMed]
  • Ranadive NS, Sajnani AN, Alimurka K, Movat HZ. Release of basic proteins and lysosomal enzymes from neutrophil leukocytes of the rabbit. Int Arch Allergy Appl Immunol. 1973;45(6):880–898. [PubMed]
  • THAL AP, SARDESAI VM. SHOCK AND THE CIRCULATING POLYPEPTIDES. Am J Surg. 1965 Sep;110:308–312. [PubMed]
  • THOMAS L. POSSIBLE ROLE OF LEUCOCYTE GRANULES IN THE SHWARTZMAN AND ARTHUS REACTIONS. Proc Soc Exp Biol Med. 1964 Jan;115:235–240. [PubMed]
  • Warren HS, Ferguson WW, Wangensteen SL. Lysosomal enzyme release in canine endotoxin shock treated with methylprednisolone. Am Surg. 1973 Nov;39(11):608–618. [PubMed]
  • WEISSMANN G, THOMAS L. Studies on lysosomes. I. The effects of endotoxin, endotoxin tolerance, and cortisone on the release of acid hydrolases from a granular fraction of rabbit liver. J Exp Med. 1962 Oct 1;116:433–450. [PMC free article] [PubMed]

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