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Journal List > Infect Immun > v.10(2); Aug 1974

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Infect Immun. 1974 August; 10(2): 409–410.
PMCID: PMC415015
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Enhanced Interferon Response to Murine Leukemia Virus by Ascorbic Acid
Benjamin V. Siegel
1Department of Pathology, University of Oregon Medical School, Portland, Oregon 97201
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Abstract
BALB/cJ mice, on an ad libitum regimen of 250 mg% l-ascorbate in their drinking water, displayed augmented levels of circulating interferon after stimulation with murine leukemia virus.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
  • Gresser I, Berman L, De Thé G, Brouty-Boyé D, Coppey J, Falcoff E. Interferon and murine leukemia. V. Effect of interferon preparations on the evolution of Rauscher disease in mice. J Natl Cancer Inst. 1968 Aug;41(2):505–522. [PubMed]
  • Gresser I, Coppey J, Falcoff E, Fontaine D. Interferon and murine leukemia. I. Inhibitory effect of interferon preparations on development of friend leukemia in mice. Proc Soc Exp Biol Med. 1967 Jan;124(1):84–91. [PubMed]
  • Klein M. THE MECHANISM OF THE VIRUCIDAL ACTION OF ASCORBIC ACID. Science. 1945 Jun 8;101(2632):587–589. [PubMed]
  • Schlegel JU, Pipkin GE, Nishimura R, Shultz GN. The role of ascorbic acid in the prevention of bladder tumor formation. J Urol. 1970 Feb;103(2):155–159. [PubMed]
  • Siegel BV, Brown M, Morton JI. Interferon induction in New Zealand black mice by murine leukemia virus. J Immunol. 1973 Aug;111(2):644–646. [PubMed]
  • Stewart WE, 2nd, Gosser LB, Lockart RZ., Jr Distinguishing characteristics of the interferon responses of primary and continuous mouse cell cultures. J Gen Virol. 1971 Oct;13(1):35–50. [PubMed]
  • WHEELOCK EF, DINGLE JH. OBSERVATIONS ON THE REPEATED ADMINISTRATION OF VIRUSES TO A PATIENT WITH ACUTE LEUKEMIA. A PRELIMINARY REPORT. N Engl J Med. 1964 Sep 24;271:645–651. [PubMed]
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