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Journal List > Proc Natl Acad Sci U S A > v.93(1); Jan 9, 1996

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Proc Natl Acad Sci U S A. 1996 January 9; 93(1): 13–20.
PMCID: PMC40170
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Principles of protein-protein interactions.
S Jones and J M Thornton
Department of Biochemistry and Molecular Biology, University College, London, England.
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Abstract
This review examines protein complexes in the Brookhaven Protein Databank to gain a better understanding of the principles governing the interactions involved in protein-protein recognition. The factors that influence the formation of protein-protein complexes are explored in four different types of protein-protein complexes--homodimeric proteins, heterodimeric proteins, enzyme-inhibitor complexes, and antibody-protein complexes. The comparison between the complexes highlights differences that reflect their biological roles.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
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