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Proc Natl Acad Sci U S A. Mar 1971; 68(3): 645–648.
PMCID: PMC389008

Serum Factor Requirements of Normal and Simian Virus 40-Transformed 3T3 Mouse Fibroblasts

Abstract

Evidence is presented to show the presence in normal rat serum of four different serum factors essential for growth of 3T3 or SV40-transformed 3T3 mouse fibroblasts: a factor that specifically promotes growth of normal 3T3 cells; two factors that specifically promote growth of transformed 3T3 cells; and a factor that sustains viability of both normal and transformed 3T3 cells in serum-free medium, probably without inducing growth of the cells. These factors are separated and partially purified.

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Selected References

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