pmc logo image
Logo of molpathJournal URL: http://www.pubmedcentral.nih.gov/tocrender.fcgi?journal=162&action=archive
Journal List > Mol Pathol > v.50(1); Feb 1997

Formats:
Mol Pathol. 1997 February; 50(1): 4–8.
PMCID: PMC379571
Copyright notice
Kaposi's sarcoma associated herpes virus (KSHV/HHV 8): epidemiology, molecular biology and tissue distribution.
J. J. O'Leary, M. M. Kennedy, and J. O. McGee
Nuffield Department of Pathology and Bacteriology, University of Oxford.
Small right arrow pointing to: This article has been cited by other articles in PMC.
Full text
Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.0M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.
 
icon of scanned page 4
4
icon of scanned page 5
5
icon of scanned page 6
6
icon of scanned page 7
7
icon of scanned page 8
8
 
Images in this article
Image
Image

Image
on p.4
Click on the image to see a larger version.
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
  • Rabkin CS, Bedi G, Musaba E, Sunkutu R, Mwansa N, Sidransky D, Biggar RJ. AIDS-related Kaposi's sarcoma is a clonal neoplasm. Clin Cancer Res. 1995 Mar;1(3):257–260. [PubMed]
  • Beral V. Epidemiology of Kaposi's sarcoma. Cancer Surv. 1991;10:5–22. [PubMed]
  • Chang Y, Cesarman E, Pessin MS, Lee F, Culpepper J, Knowles DM, Moore PS. Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science. 1994 Dec 16;266(5192):1865–1869. [PubMed]
  • Moore PS, Gao SJ, Dominguez G, Cesarman E, Lungu O, Knowles DM, Garber R, Pellett PE, McGeoch DJ, Chang Y. Primary characterization of a herpesvirus agent associated with Kaposi's sarcomae. J Virol. 1996 Jan;70(1):549–558. [PubMed]
  • O'Leary JJ. Seeking the cause of Kaposi's sarcoma. Nat Med. 1996 Aug;2(8):862–863. [PubMed]
  • Moore PS, Chang Y. Detection of herpesvirus-like DNA sequences in Kaposi's sarcoma in patients with and without HIV infection. N Engl J Med. 1995 May 4;332(18):1181–1185. [PubMed]
  • Collandre H, Ferris S, Grau O, Montagnier L, Blanchard A. Kaposi's sarcoma and new herpesvirus. Lancet. 1995 Apr 22;345(8956):1043–1043. [PubMed]
  • Boshoff C, Whitby D, Hatziioannou T, Fisher C, van der Walt J, Hatzakis A, Weiss R, Schulz T. Kaposi's-sarcoma-associated herpesvirus in HIV-negative Kaposi's sarcoma. Lancet. 1995 Apr 22;345(8956):1043–1044. [PubMed]
  • Schalling M, Ekman M, Kaaya EE, Linde A, Biberfeld P. A role for a new herpes virus (KSHV) in different forms of Kaposi's sarcoma. Nat Med. 1995 Jul;1(7):707–708. [PubMed]
  • Noel JC. Kaposi's sarcoma and KSHV. Lancet. 1995 Nov 18;346(8986):1359. [PubMed]
  • Cesarman E, Chang Y, Moore PS, Said JW, Knowles DM. Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas. N Engl J Med. 1995 May 4;332(18):1186–1191. [PubMed]
  • Soulier J, Grollet L, Oksenhendler E, Cacoub P, Cazals-Hatem D, Babinet P, d'Agay MF, Clauvel JP, Raphael M, Degos L, et al. Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease. Blood. 1995 Aug 15;86(4):1276–1280. [PubMed]
  • Ansari MQ, Dawson DB, Nador R, Rutherford C, Schneider NR, Latimer MJ, Picker L, Knowles DM, McKenna RW. Primary body cavity-based AIDS-related lymphomas. Am J Clin Pathol. 1996 Feb;105(2):221–229. [PubMed]
  • Lin JC, Lin SC, Mar EC, Pellett PE, Stamey FR, Stewart JA, Spira TJ. Is Kaposi's-sarcoma-associated herpesvirus detectable in semen of HIV-infected homosexual men? Lancet. 1995 Dec 16;346(8990):1601–1602. [PubMed]
  • Monini P, de Lellis L, Fabris M, Rigolin F, Cassai E. Kaposi's sarcoma-associated herpesvirus DNA sequences in prostate tissue and human semen. N Engl J Med. 1996 May 2;334(18):1168–1172. [PubMed]
  • Corbellino M, Bestetti G, Galli M, Parravicini C. Absence of HHV-8 in prostate and semen. N Engl J Med. 1996 Oct 17;335(16):1237–1239. [PubMed]
  • Tasaka T, Said JW, Koeffler HP. Absence of HHV-8 in prostate and semen. N Engl J Med. 1996 Oct 17;335(16):1237–1239. [PubMed]
  • Rady PL, Yen A, Rollefson JL, Orengo I, Bruce S, Hughes TK, Tyring SK. Herpesvirus-like DNA sequences in non-Kaposi's sarcoma skin lesions of transplant patients. Lancet. 1995 May 27;345(8961):1339–1340. [PubMed]
  • Boshoff C, Talbot S, Kennedy M, O'Leary J, Schulz T, Chang Y. HHV8 and skin cancers in immunosuppressed patients. Lancet. 1996 Feb 3;347(8997):338–339. [PubMed]
  • Dictor M, Rambech E, Way D, Witte M, Bendsöe N. Human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus) DNA in Kaposi's sarcoma lesions, AIDS Kaposi's sarcoma cell lines, endothelial Kaposi's sarcoma simulators, and the skin of immunosuppressed patients. Am J Pathol. 1996 Jun;148(6):2009–2016. [PubMed]
  • Boshoff C, Schulz TF, Kennedy MM, Graham AK, Fisher C, Thomas A, McGee JO, Weiss RA, O'Leary JJ. Kaposi's sarcoma-associated herpesvirus infects endothelial and spindle cells. Nat Med. 1995 Dec;1(12):1274–1278. [PubMed]
  • Li JJ, Huang YQ, Cockerell CJ, Friedman-Kien AE. Localization of human herpes-like virus type 8 in vascular endothelial cells and perivascular spindle-shaped cells of Kaposi's sarcoma lesions by in situ hybridization. Am J Pathol. 1996 Jun;148(6):1741–1748. [PubMed]
  • Whitby D, Howard MR, Tenant-Flowers M, Brink NS, Copas A, Boshoff C, Hatzioannou T, Suggett FE, Aldam DM, Denton AS, et al. Detection of Kaposi sarcoma associated herpesvirus in peripheral blood of HIV-infected individuals and progression to Kaposi's sarcoma. Lancet. 1995 Sep 23;346(8978):799–802. [PubMed]
  • Walter PR, Philippe E, Nguemby-Mbina C, Chamlian A. Kaposi's sarcoma: presence of herpes-type virus particles in a tumor specimen. Hum Pathol. 1984 Dec;15(12):1145–1146. [PubMed]
  • Nickoloff BJ, Foreman KE. Charting a new course through the chaos of KS (Kaposi's sarcoma). Am J Pathol. 1996 May;148(5):1323–1329. [PubMed]
  • Renne R, Zhong W, Herndier B, McGrath M, Abbey N, Kedes D, Ganem D. Lytic growth of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in culture. Nat Med. 1996 Mar;2(3):342–346. [PubMed]
  • Giraldo G, Beth E, Haguenau F. Herpes-type virus particles in tissue culture of Kaposi's sarcoma from different geographic regions. J Natl Cancer Inst. 1972 Dec;49(6):1509–1526. [PubMed]
  • Kedes DH, Operskalski E, Busch M, Kohn R, Flood J, Ganem D. The seroepidemiology of human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus): distribution of infection in KS risk groups and evidence for sexual transmission. Nat Med. 1996 Aug;2(8):918–924. [PubMed]
  • Gao SJ, Kingsley L, Li M, Zheng W, Parravicini C, Ziegler J, Newton R, Rinaldo CR, Saah A, Phair J, Detels R, Chang Y, Moore PS. KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi's sarcoma. Nat Med. 1996 Aug;2(8):925–928. [PubMed]
  • Gao SJ, Kingsley L, Hoover DR, Spira TJ, Rinaldo CR, Saah A, Phair J, Detels R, Parry P, Chang Y, Moore PS. Seroconversion to antibodies against Kaposi's sarcoma-associated herpesvirus-related latent nuclear antigens before the development of Kaposi's sarcoma. N Engl J Med. 1996 Jul 25;335(4):233–241. [PubMed]
  • Zhong W, Wang H, Herndier B, Ganem D. Restricted expression of Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genes in Kaposi sarcoma. Proc Natl Acad Sci U S A. 1996 Jun 25;93(13):6641–6646. [PubMed]
  • Stürzl M, Roth WK, Brockmeyer NH, Zietz C, Speiser B, Hofschneider PH. Expression of platelet-derived growth factor and its receptor in AIDS-related Kaposi sarcoma in vivo suggests paracrine and autocrine mechanisms of tumor maintenance. Proc Natl Acad Sci U S A. 1992 Aug 1;89(15):7046–7050. [PubMed]
  • Miles SA, Rezai AR, Salazar-González JF, Vander Meyden M, Stevens RH, Logan DM, Mitsuyasu RT, Taga T, Hirano T, Kishimoto T, et al. AIDS Kaposi sarcoma-derived cells produce and respond to interleukin 6. Proc Natl Acad Sci U S A. 1990 Jun;87(11):4068–4072. [PubMed]
  • Ensoli B, Gendelman R, Markham P, Fiorelli V, Colombini S, Raffeld M, Cafaro A, Chang HK, Brady JN, Gallo RC. Synergy between basic fibroblast growth factor and HIV-1 Tat protein in induction of Kaposi's sarcoma. Nature. 1994 Oct 20;371(6499):674–680. [PubMed]
  • Pammer J, Plettenberg A, Weninger W, Diller B, Mildner M, Uthman A, Issing W, Stürzl M, Tschachler E. CD40 antigen is expressed by endothelial cells and tumor cells in Kaposi's sarcoma. Am J Pathol. 1996 May;148(5):1387–1396. [PubMed]
  • Motokura T, Arnold A. Cyclins and oncogenesis. Biochim Biophys Acta. 1993 May 25;1155(1):63–78. [PubMed]
  • Nicholas J, Cameron KR, Honess RW. Herpesvirus saimiri encodes homologues of G protein-coupled receptors and cyclins. Nature. 1992 Jan 23;355(6358):362–365. [PubMed]
  • Chang Y, Moore PS, Talbot SJ, Boshoff CH, Zarkowska T, Godden-Kent, Paterson H, Weiss RA, Mittnacht S. Cyclin encoded by KS herpesvirus. Nature. 1996 Aug 1;382(6590):410–410. [PubMed]
  • Ambroziak JA, Blackbourn DJ, Herndier BG, Glogau RG, Gullett JH, McDonald AR, Lennette ET, Levy JA. Herpes-like sequences in HIV-infected and uninfected Kaposi's sarcoma patients. Science. 1995 Apr 28;268(5210):582–583. [PubMed]
  • Huang YQ, Li JJ, Kaplan MH, Poiesz B, Katabira E, Zhang WC, Feiner D, Friedman-Kien AE. Human herpesvirus-like nucleic acid in various forms of Kaposi's sarcoma. Lancet. 1995 Mar 25;345(8952):759–761. [PubMed]
  • European medicines in the 21st century. Lancet. 1995 Jan 7;345(8941):1–2. [PubMed]
  • Rady PL, Yen A, Martin RW, 3rd, Nedelcu I, Hughes TK, Tyring SK. Herpesvirus-like DNA sequences in classic Kaposi's sarcomas. J Med Virol. 1995 Oct;47(2):179–183. [PubMed]
  • Chang Y, Ziegler J, Wabinga H, Katangole-Mbidde E, Boshoff C, Schulz T, Whitby D, Maddalena D, Jaffe HW, Weiss RA, Moore PS. Kaposi's sarcoma-associated herpesvirus and Kaposi's sarcoma in Africa. Uganda Kaposi's Sarcoma Study Group. Arch Intern Med. 1996 Jan 22;156(2):202–204. [PubMed]
  • Moore PS, Kingsley LA, Holmberg SD, Spira T, Gupta P, Hoover DR, Parry JP, Conley LJ, Jaffe HW, Chang Y. Kaposi's sarcoma-associated herpesvirus infection prior to onset of Kaposi's sarcoma. AIDS. 1996 Feb;10(2):175–180. [PubMed]
  • Miller G, Rigsby MO, Heston L, Grogan E, Sun R, Metroka C, Levy JA, Gao SJ, Chang Y, Moore P. Antibodies to butyrate-inducible antigens of Kaposi's sarcoma-associated herpesvirus in patients with HIV-1 infection. N Engl J Med. 1996 May 16;334(20):1292–1297. [PubMed]
  • Lennette ET, Blackbourn DJ, Levy JA. Antibodies to human herpesvirus type 8 in the general population and in Kaposi's sarcoma patients. Lancet. 1996 Sep 28;348(9031):858–861. [PubMed]
  • HIV: a war still to be won. Lancet. 1996 Jul 6;348(9019):1. [PubMed]
Articles from Molecular Pathology : MP are provided here courtesy of
BMJ Group

PubMed articles by these authors

Links