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Appl Microbiol. Sep 1972; 24(3): 384–388.
PMCID: PMC376528

Hydrodynamic Focusing and Electronic Cell-Sizing Techniques

Abstract

The technique of hydrodynamic focusing, used to improve the resolution of the Coulter counter for the sizing of bacteria, was examined. Latex particles of 0.26 μm3 to 6.7 μm3 volume were used to examine the characteristics of the system with and without hydrodynamic focusing. The system then was evaluated for sizing mixed bacterial populations as well as single populations. Possible applications are also discussed.

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Selected References

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  • Harvey RJ, Marr AG. Measurement of size distributions of bacterial cells. J Bacteriol. 1966 Oct;92(4):805–811. [PMC free article] [PubMed]
  • KUBITSCHEK HE. Electronic counting and sizing of bacteria. Nature. 1958 Jul 26;182(4630):234–235. [PubMed]

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