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Mol Cell Biol. Mar 1989; 9(3): 1368–1370.
PMCID: PMC362735

Acquisition and processing of a conditional dicentric chromosome in Saccharomyces cerevisiae.


The introduction of a conditional centromere into chromosome III of Saccharomyces cerevisiae provided an opportunity to evaluate phenotypic and karyotypic consequences in cells harboring dicentric chromosomes upon entry into mitosis. A mitotic pause ensued, and monocentric derivatives of chromosome III were generated at a high frequency.

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Selected References

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