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Proc Natl Acad Sci U S A. 1982 Dec; 79(24): 7809–7813.
PMCID: PMC347438

Chromosomal localization of human leukocyte, fibroblast, and immune interferon genes by means of in situ hybridization


Recombinant plasmids containing cDNA inserts from human leukocyte interferon (IFN-α), fibroblast interferon (IFN-β), or immune interferon (INF-γ) genes were radiolabeled and hybridized in situ to human metaphase chromosome preparations. The results localized the human IFN-α and IFN-β genes to the short arm of chromosome 9(p21→pter) and localized the IFN-γ gene to the long arm of chromosome 12(q24.1).

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Selected References

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