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Indian J Surg. Apr 2009; 71(2): 73–77.
Published online May 2, 2009. doi:  10.1007/s12262-009-0020-9
PMCID: PMC3452607

The effect of Kombucha on post-operative intra-abdominal adhesion formation in rats



Peritoneal adhesions are fibrous bands of tissues formed between organs that are normally separated and/or between organs and the internal body wall after peritoneal injury. The aim of the study was to investigate the effect of intra-peritoneal administration of Kombucha on intra-peritoneal adhesions.

Materials and methods

Eighty Wistar rats were subjected to standardized lesion by scraping model and were randomly divided into two groups. Group I received no treatment, and Group II received 15 ml of Kombucha solution intra-peritoneally. On the post-operative 14th day adhesion intensity score, inflammatory cell reaction and number of adhesion bands were determined.


In the control group, there were no rats with grade 0 and I adhesions. In the group II, there were 26 rats (78.8%) with grade 0–2 adhesions. Adhesion intensity was significantly less in group II (P<0.0001). Number of adhesion bands was significantly less in group II (P<0.001).


It was concluded that intra-peritoneal administration of Kombucha might be useful for preventing peritoneal adhesions.

Keywords: Peritoneal adhesions, Kombucha, Prevention

Full Text

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
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