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Nucleic Acids Res. Jun 11, 1979; 6(7): 2601–2610.
PMCID: PMC327874

A strategy of DNA sequencing employing computer programs.

Abstract

With modern fast sequencing techniques and suitable computer programs it is now possible to sequence whole genomes without the need of restriction maps. This paper describes computer programs that can be used to order both sequence gel readings and clones. A method of coding for uncertainties in gel readings is described. These programs are available on request.

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Selected References

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  • Maxam AM, Gilbert W. A new method for sequencing DNA. Proc Natl Acad Sci U S A. 1977 Feb;74(2):560–564. [PMC free article] [PubMed]
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  • Staden R. Further procedures for sequence analysis by computer. Nucleic Acids Res. 1978 Mar;5(3):1013–1016. [PMC free article] [PubMed]

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