Logo of thijCurrent IssueSee also Cardiovascular Diseases Journal in PMCSubscribeSubmissionsTHI Journal Website
Tex Heart Inst J. 1991; 18(2): 127–131.
PMCID: PMC324980

Myopericarditis in Churg-Strauss Syndrome


Churg-Strauss syndrome is a disseminated vasculitis with multisystem involvement, characterized by necrotizing arteritis, eosinophilic infiltration, and extravascular granuloma formation. In as many as 60% of all cases, the heart may be affected. We describe a 30-year-old man in whom pericarditis was followed by the development of a large pericardial effusion, with evidence of impaired right and left ventricular function. The patient had a 5-year history of asthma. Early therapy with high-dose prednisolone and azathioprine led to resolution of the pericardial effusion and prevented a further reduction in biventricular function. (Texas Heart Institute Journal 1991;18:127-31)

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.1M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Images in this article

Click on the image to see a larger version.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • CHURG J, STRAUSS L. Allergic granulomatosis, allergic angiitis, and periarteritis nodosa. Am J Pathol. 1951 Mar-Apr;27(2):277–301. [PMC free article] [PubMed]
  • Lanham JG, Elkon KB, Pusey CD, Hughes GR. Systemic vasculitis with asthma and eosinophilia: a clinical approach to the Churg-Strauss syndrome. Medicine (Baltimore) 1984 Mar;63(2):65–81. [PubMed]
  • Chumbley LC, Harrison EG, Jr, DeRemee RA. Allergic granulomatosis and angiitis (Churg-Strauss syndrome). Report and analysis of 30 cases. Mayo Clin Proc. 1977 Aug;52(8):477–484. [PubMed]
  • Davison AG, Thompson PJ, Davies J, Corrin B, Turner-Warwick M. Prominent pericardial and myocardial lesions in the Churg-Strauss syndrome (allergic granulomatosis and angiitis). Thorax. 1983 Oct;38(10):793–795. [PMC free article] [PubMed]
  • Morgan JM, Raposo L, Gibson DG. Cardiac involvement in Churg-Strauss syndrome shown by echocardiography. Br Heart J. 1989 Dec;62(6):462–466. [PMC free article] [PubMed]
  • Thomson D, Chamsi-Pasha H, Hasleton P. Heart transplantation for Churg-Strauss syndrome. Br Heart J. 1989 Nov;62(5):409–410. [PMC free article] [PubMed]
  • Lie JT. The classification of vasculitis and a reappraisal of allergic granulomatosis and angiitis (Churg-Strauss syndrome). Mt Sinai J Med. 1986 Jun;53(6):429–439. [PubMed]
  • Lie JT, Bayardo RJ. Isolated eosinophilic coronary arteritis and eosinophilic myocarditis. A limited form of Churg-Strauss syndrome. Arch Pathol Lab Med. 1989 Feb;113(2):199–201. [PubMed]
  • Lanham JG, Cooke S, Davies J, Hughes GR. Endomyocardial complications of the Churg-Strauss syndrome. Postgrad Med J. 1985 Apr;61(714):341–344. [PMC free article] [PubMed]
  • Olsen EG, Spry CJ. Relation between eosinophilia and endomyocardial disease. Prog Cardiovasc Dis. 1985 Jan-Feb;27(4):241–254. [PubMed]
  • Tai PC, Spry CJ. Enzymes altering the binding capacity of human blood eosinophils for IgG antibody-coated erythrocytes (EA). Clin Exp Immunol. 1980 Apr;40(1):206–219. [PMC free article] [PubMed]
  • Pincus SH, Schooley WR, DiNapoli AM, Broder S. Metabolic heterogeneity of eosinophils from normal and hypereosinophilic patients. Blood. 1981 Dec;58(6):1175–1181. [PubMed]
  • Tai PC, Hayes DJ, Clark JB, Spry CJ. Toxic effects of human eosinophil products on isolated rat heart cells in vitro. Biochem J. 1982 Apr 15;204(1):75–80. [PMC free article] [PubMed]

Articles from Texas Heart Institute Journal are provided here courtesy of Texas Heart Institute


Related citations in PubMed

See reviews...See all...


  • MedGen
    Related information in MedGen
  • PubMed
    PubMed citations for these articles

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...