Logo of narLink to Publisher's site
Nucleic Acids Res. 1989 Jul 11; 17(13): 5273–5290.
PMCID: PMC318110

The isochore organization and the compositional distribution of homologous coding sequences in the nuclear genome of plants.


The isochore structure of the nuclear genome of angiosperms described by Salinas et al. (1) was confirmed by using a different experimental approach, namely by showing that the levels of coding sequences from both dicots and Gramineae are linearly correlated with GC levels of the corresponding flanking sequences. The compositional distribution of homologous coding sequences from several orders of dicots and from Gramineae were also studied and shown to mimick the compositional distributions previously seen (1) for coding sequences in general, most coding sequences from Gramineae being much higher than those of the dicots explored. These differences were even stronger for third codon positions and led to striking codon usages for many coding sequences especially in the case of Gramineae.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.3M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Salinas J, Matassi G, Montero LM, Bernardi G. Compositional compartmentalization and compositional patterns in the nuclear genomes of plants. Nucleic Acids Res. 1988 May 25;16(10):4269–4285. [PMC free article] [PubMed]
  • Bernardi G, Olofsson B, Filipski J, Zerial M, Salinas J, Cuny G, Meunier-Rotival M, Rodier F. The mosaic genome of warm-blooded vertebrates. Science. 1985 May 24;228(4702):953–958. [PubMed]
  • Gouy M, Milleret F, Mugnier C, Jacobzone M, Gautier C. ACNUC: a nucleic acid sequence data base and analysis system. Nucleic Acids Res. 1984 Jan 11;12(1 Pt 1):121–127. [PMC free article] [PubMed]
  • Sharp PM, Tuohy TM, Mosurski KR. Codon usage in yeast: cluster analysis clearly differentiates highly and lowly expressed genes. Nucleic Acids Res. 1986 Jul 11;14(13):5125–5143. [PMC free article] [PubMed]
  • Ingle J, Pearson GG, Sinclair J. Species distribution and properties of nuclear satellite DNA in higher plants. Nat New Biol. 1973 Apr 18;242(120):193–197. [PubMed]
  • Perrin P, Bernardi G. Directional fixation of mutations in vertebrate evolution. J Mol Evol. 1987;26(4):301–310. [PubMed]
  • Bernardi G, Mouchiroud D, Gautier C, Bernardi G. Compositional patterns in vertebrate genomes: conservation and change in evolution. J Mol Evol. 1988 Dec;28(1-2):7–18. [PubMed]
  • Ikemura T. Codon usage and tRNA content in unicellular and multicellular organisms. Mol Biol Evol. 1985 Jan;2(1):13–34. [PubMed]
  • Murray EE, Lotzer J, Eberle M. Codon usage in plant genes. Nucleic Acids Res. 1989 Jan 25;17(2):477–498. [PMC free article] [PubMed]
  • Grantham R, Gautier C, Gouy M. Codon frequencies in 119 individual genes confirm consistent choices of degenerate bases according to genome type. Nucleic Acids Res. 1980 May 10;8(9):1893–1912. [PMC free article] [PubMed]
  • Grantham R, Gautier C, Gouy M, Mercier R, Pavé A. Codon catalog usage and the genome hypothesis. Nucleic Acids Res. 1980 Jan 11;8(1):r49–r62. [PMC free article] [PubMed]
  • Grantham R, Gautier C, Gouy M, Jacobzone M, Mercier R. Codon catalog usage is a genome strategy modulated for gene expressivity. Nucleic Acids Res. 1981 Jan 10;9(1):r43–r74. [PMC free article] [PubMed]
  • Bernardi G, Bernardi G. Compositional constraints and genome evolution. J Mol Evol. 1986;24(1-2):1–11. [PubMed]
  • Antequera F, Bird AP. Unmethylated CpG islands associated with genes in higher plant DNA. EMBO J. 1988 Aug;7(8):2295–2299. [PMC free article] [PubMed]
  • Brinkmann H, Martinez P, Quigley F, Martin W, Cerff R. Endosymbiotic origin and codon bias of the nuclear gene for chloroplast glyceraldehyde-3-phosphate dehydrogenase from maize. J Mol Evol. 1987;26(4):320–328. [PubMed]

Articles from Nucleic Acids Research are provided here courtesy of Oxford University Press


Save items

Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...


  • PubMed
    PubMed citations for these articles
  • Substance
    PubChem chemical substance records that cite the current articles. These references are taken from those provided on submitted PubChem chemical substance records.

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...