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Molecular monitoring of the Leu-164 mutation of dihydrofolate reductase in a highly sulfadoxine/pyrimethamine-resistant area in Africa
Edwin Ochong, Alexis Nzila, Serah Kimani, Gilbert Kokwaro, Theonest Mutabingwa, William Watkins, Kevin Marsh
Malar J. 2003; 2: 46. Published online 2003 December 15. doi: 10.1186/1475-2875-2-46
PMCID:
PMC317348
Abstract Full Text PDF–207K
 Is Cited by the Following 3 Articles in this Archive:
In Vitro Activity of Antifolate and Polymorphism in Dihydrofolate Reductase of Plasmodium falciparum Isolates from the Kenyan Coast: Emergence of Parasites with Ile-164-Leu Mutation
Steven M. Kiara, John Okombo, Victor Masseno, Leah Mwai, Isabella Ochola, Steffen Borrmann, Alexis Nzila
Antimicrob Agents Chemother. 2009 September; 53(9): 3793–3798. Published online 2009 June 15. doi: 10.1128/AAC.00308-09
PMCID:
PMC2737895
Abstract Full Text PDF–74K
Chloroquine resistance before and after its withdrawal in Kenya
Leah Mwai, Edwin Ochong, Abdi Abdirahman, Steven M Kiara, Steve Ward, Gilbert Kokwaro, Philip Sasi, Kevin Marsh, Steffen Borrmann, Margaret Mackinnon, Alexis Nzila
Malar J. 2009; 8: 106. Published online 2009 May 18. doi: 10.1186/1475-2875-8-106
PMCID:
PMC2694831
Abstract Full Text PDF–334K Supplementary Material
Plasmodium falciparum Strains Harboring Dihydrofolate Reductase with the I164L Mutation Are Absent in Malawi and Zambia Even under Antifolate Drug Pressure
Edwin Ochong, David J. Bell, David J. Johnson, Umberto D'Alessandro, Modest Mulenga, Sant Muangnoicharoen, Jean-Pierre Van Geertruyden, Peter A. Winstanley, Patrick G. Bray, Stephen A. Ward, Andrew Owen
Antimicrob Agents Chemother. 2008 November; 52(11): 3883–3888. Published online 2008 August 25. doi: 10.1128/AAC.00431-08
PMCID:
PMC2573156
Abstract Full Text PDF–380K
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