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Journal List > Infect Immun > v.61(2); Feb 1993

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Infect Immun. 1993 February; 61(2): 781–784.
PMCID: PMC302795
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Opsonization of Treponema pallidum is mediated by immunoglobulin G antibodies induced only by pathogenic treponemes.
J M Shaffer, S A Baker-Zander, and S A Lukehart
Department of Medicine, University of Washington, Seattle 98195.
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Abstract
Rabbit antisera to Leptospira interrogans, Borrelia hermsii, and Treponema phagedenis biotype Reiter, reactive to shared spirochetal antigens, failed to enhance phagocytosis of Treponema pallidum by macrophages, while immunoglobulin G to Treponema pallidum subsp. pertenue and Treponema paraluiscuniculi promoted phagocytosis. Opsonic antibodies are directed to pathogen-restricted, not shared spirochetal, antigens.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
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