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PMC full text:
Circ Res. Author manuscript; available in PMC 2011 Sep 3.
Published in final edited form as:
Circ Res. 2010 Sep 3; 107(5): 659–666.
Published online 2010 Jul 8. doi:  10.1161/CIRCRESAHA.110.220038

Figure 3

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Low–expressing IP3R2 DTG mice demonstrate enhanced cardiac hypertrophy only to Iso infusion and swimming. (A,B) HW/BW and myocyte cross-sectional areas from control (tTA) and IP3R2 DTG (line 4.9) mice 2 weeks after sham or TAC without Dox (induced). *P<0.05 versus sham, (C,D) HW/BW and myocyte cross-sectional areas in the indicated groups (DTG, line 4.9) of mice 2 weeks after Iso infusion or Veh, without Dox (induced). *P<0.05 versus Veh., P<0.05 versus tTA Iso. (E,F) HW/BW and myocyte cross-sectional areas for control (tTA) and IP3R2-DTG (line 4.9) mice 2 weeks after Iso/Veh infusion with Dox present in the drinking water (transgene off). (G,H) HW/BW after 3 weeks of swimming exercise in tTA or IP3R2 DTG (line 4.9 and line 3.11) without Dox (induced). * P<0.05 versus rest and P<0.05 versus tTA swim. Numbers in the bars indicate mice or samples analyzed.

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