Logo of jcinvestThe Journal of Clinical InvestigationCurrent IssueArchiveSubscriptionAbout the Journal
J Clin Invest. Apr 1966; 45(4): 612–619.
PMCID: PMC292735

Renal gluconeogenesis in acidosis, alkalosis, and potassium deficiency: its possible role in regulation of renal ammonia production.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.1M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • LEONARD E, ORLOFF J. Regulation of ammonia excretion in the rat. Am J Physiol. 1955 Jul;182(1):131–138. [PubMed]
  • PITTS RF, DEHAAS J, KLEIN J. Relation of renal amino and amide nitrogen extraction to ammonia production. Am J Physiol. 1963 Feb;204:187–191. [PubMed]
  • OWEN EE, ROBINSON RR. Amino acid extraction and ammonia metabolism by the human kidney during the prolonged administration of ammonium chloride. J Clin Invest. 1963 Feb;42:263–276. [PMC free article] [PubMed]
  • DAVIES BMA, YUDKIN J. Studies in biochemical adaptation; the origin or urinary ammonia as indicated by the effect of chronic acidosis and alkalosis on some renal enzymes in the rat. Biochem J. 1952 Nov;52(3):407–412. [PMC free article] [PubMed]
  • GOLDSTEIN L, COPENHAVER JH., Jr Relation of glutaminase I activity to glutamic acid concentration in the rat kidney. Am J Physiol. 1960 Feb;198:227–229. [PubMed]
  • MOYED HS, UMBARGER HE. Regulation of biosynthetic pathways. Physiol Rev. 1962 Jul;42:444–466. [PubMed]
  • KREBS HA, BENNETT DA, DE GASQUET P, GASQUET P, GASCOYNE T, YOSHIDA T. Renal gluconeogenesis. The effect of diet on the gluconeogenic capacity of rat-kidney-cortex slices. Biochem J. 1963 Jan;86:22–27. [PMC free article] [PubMed]
  • IACOBELLIS M, MUNTWYLER E, GRIFFIN GE. Enzyme concentration changes in the kidneys of protein- and/or potassium-deficient rats. Am J Physiol. 1954 Sep;178(3):477–482. [PubMed]
  • GOLDSTEIN L. RELATION OF RENAL GLUTSMINE TRANSEMINASE-OMEGA-AMIDASE ACTIVITY TO AMMONIA EXCRETION IN THE RAT. Nature. 1964 Mar 21;201:1229–1230. [PubMed]
  • HUGGETT AS, NIXON DA. Use of glucose oxidase, peroxidase, and O-dianisidine in determination of blood and urinary glucose. Lancet. 1957 Aug 24;273(6991):368–370. [PubMed]
  • LANDAU BR. Gluconeogenesis and pyruvate metabolism in rat kidney, in vitro. Endocrinology. 1960 Dec;67:744–751. [PubMed]
  • FREEDMAN JK, POTTS AM. Repression of glutaminase I in the rat retina by administration of sodium-L-glutamate II. Invest Ophthalmol. 1963 Jun;2:252–258. [PubMed]
  • KLINGMAN JD, HANDLER P. Partial purification and properties of renal glutaminase. J Biol Chem. 1958 May;232(1):369–380. [PubMed]
  • DZURIK R, KRAJCI LAZARY B, NIEDERLAND TR. GLUCOSE METABOLISM IN RAT KIDNEY: INFLUENCE OF INSULIN AND ADRENALINE. J Physiol. 1963 Oct;168:782–786. [PMC free article] [PubMed]
  • McCANN WP, JUDE JR. The synthesis of glucose by the kidney. Bull Johns Hopkins Hosp. 1958 Aug;103(2):77–93. [PubMed]
  • SAGILD U, ANDERSEN V, ANDREASEN PB. Glucose tolerance and insulin responsiveness in experimental potassium depletion. Acta Med Scand. 1961 Mar;169:243–251. [PubMed]
  • COHEN JJ, WITTMANN E. Renal utilization and excretion of alpha-ketoglutarate in dog: effect of alkalosis. Am J Physiol. 1963 May;204:795–811. [PubMed]
  • UTTER MF. The role of CO2 fixation in carbohydrate utilization and synthesis. Ann N Y Acad Sci. 1959 Feb 6;72(12):451–461. [PubMed]
  • SELLECK BH, COHEN JJ. SPECIFIC LOCALIZATION OF ALPHA-KETOGLUTARATE UPTAKE TO DOG KIDNEY AND LIVER IN VIVO. Am J Physiol. 1965 Jan;208:24–37. [PubMed]
  • COHEN JJ. High respiratory quotient of dog kidney in vivo. Am J Physiol. 1960 Sep;199:560–568. [PubMed]

Articles from The Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

Formats:

Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...

Links

  • Compound
    Compound
    PubChem Compound links
  • PubMed
    PubMed
    PubMed citations for these articles
  • Substance
    Substance
    PubChem Substance links

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...