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J Clin Invest. Jul 1961; 40(7): 1304–1314.
PMCID: PMC290843

URIC ACID PRODUCTION IN GOUT

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Selected References

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  • BENEDICT JD, FORSHAM PH, STETTEN D., Jr The metabolism of uric acid in the normal and gouty human studied with the aid of isotopic uric acid. J Biol Chem. 1949 Nov;181(1):183–193. [PubMed]
  • BISHOP C, GARNER W, TALBOTT JH. Pool size, turnover rate, and rapidity of equilibration of injected isotopic uric acid in normal and pathological subjects. J Clin Invest. 1951 Aug;30(8):879–888. [PMC free article] [PubMed]
  • BENEDICT JD, ROCHE M, YU TF, BIEN EJ, GUTMAN AB, STETTEN D., Jr Incorporation of glycine nitrogen into uric acid in normal and gouty man. Metabolism. 1952 Jan;1(1):3–12. [PubMed]
  • BENEDICT JD, YU TF, BIEN EJ, GUTMAN AB, STETTEN D., Jr A further study of the utilization of dietary glycine nitrogen for uric acid synthesis in gout. J Clin Invest. 1953 Aug;32(8):775–777. [PMC free article] [PubMed]
  • WYNGAARDEN JB. Overproduction of uric acid as the cause of hyperuricemia in primary gout. J Clin Invest. 1957 Oct;36(10):1508–1515. [PMC free article] [PubMed]
  • SEEGMILLER JE, LASTER L, LIDDLE LV. Failure to detect consistent overincorporation of glycine-1-C14 into uric acid in primary gout. Metabolism. 1958 Jul;7(4 Pt 1):376–377. [PubMed]
  • WYNGAARDEN JB. Normal glycine-C14-incorporation into uric acid in primary gout. Metabolism. 1958 Jul;7(4 Pt 1):374–375. [PubMed]
  • GUTMAN AB, YU TF, BLACK H, YALOW RS, BERSON SA. Incorporation of glycine-1-C14, glycine-2-C14 and glycine-N15 into uric acid in normal and gouty subjects. Am J Med. 1958 Dec;25(6):917–932. [PubMed]
  • LIDDLE L, SEEGMILLER JE, LASTER L. The enzymatic spectrophotometric method for determination of uric acid. J Lab Clin Med. 1959 Dec;54:903–913. [PubMed]
  • GRAYZEL AI, SEEGMILLER JE, LOVE E. Suppression of uric acid synthesis in the gouty human by the use of 6-diazo-5-oxo-L-norleucine. J Clin Invest. 1960 Mar;39:447–454. [PMC free article] [PubMed]
  • GUTMAN AB, YU TF. Renal function in gout; with a commentary on the renal regulation of urate excretion, and the role of the kidney in the pathogenesis of gout. Am J Med. 1957 Oct;23(4):600–622. [PubMed]
  • BENEDICT JD, FORSHAM PH, ROCHE M, SOLOWAY S, STETTEN D., Jr The effect of salicylates and adrenocorticotropic hormone upon the miscible pool of uric acid in gout. J Clin Invest. 1950 Aug;29(8):1104–1111. [PMC free article] [PubMed]
  • BENEDICT JD, KALINSKY HJ, SCARRONE LA, WERTBEIM AR, STETTEN D., Jr The origin of urinary creatine in progressive muscular dystrophy. J Clin Invest. 1955 Jan;34(1):141–145. [PMC free article] [PubMed]
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  • OREN BG, RICH M, BELLE MS. Chlorothiazide (diuril) as a hyperuricaci'emic agent. J Am Med Assoc. 1958 Dec 20;168(16):2128–2129. [PubMed]
  • ARONOFF A. Acute gouty arthritis precipitated by chlorothiazide. N Engl J Med. 1960 Apr 14;262:767–769. [PubMed]
  • HEALEY LA, MAGID GJ, DECKER JL. Uric acid retention due to hydrochlorothiazide. N Engl J Med. 1959 Dec 31;261:1358–1362. [PubMed]
  • CULLEN JH, LEVINE M, FIORE JM. Studies of hyperuricemia produced by pyrazinamide. Am J Med. 1957 Oct;23(4):587–595. [PubMed]
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  • YU TF, SIROTA JH, BERGER L, HALPERN M, GUTMAN AB. Effect of sodium lactate infusion on urate clearance in man. Proc Soc Exp Biol Med. 1957 Dec;96(3):809–813. [PubMed]
  • HANDLER JS. The role of lactic acid in the reduced excretion of uric acid in toxemia of pregnancy. J Clin Invest. 1960 Oct;39:1526–1532. [PMC free article] [PubMed]

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