• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of epidinfectJournal HomepageSubscribeSumbitJournal Homepage
Epidemiol Infect. Feb 2001; 126(1): 19–23.
PMCID: PMC2869668

P fimbriae and aerobactin as intestinal colonization factors for Escherichia coli in Pakistani infants.


The carriage rate of a range of virulence genes was compared between resident and transient Escherichia coli strains obtained from the rectal flora of 22 home-delivered Pakistani infants 0-6 months old. Genes for the following virulence factors were assessed using multiplex PCR: P, type 1 and S fimbriae, three P fimbrial adhesin varieties, Dr haemagglutinin, K1 and K5 capsule, haemolysin and aerobactin. The E. coli strains examined here differed from those previously obtained from hosts in Western Europe in a lower prevalence of genes for P, S and type 1 fimbriae, K1 capsule and haemolysin. Nevertheless, genes for P fimbriae, the class II variety of papG adhesin, and aerobactin were significantly more common among resident than transient strains, as previously observed in a Swedish study. The results suggest that P fimbriae and aerobactin, previously implicated as virulence factors for urinary tract infection, might contribute to persistence of E. coli in the normal intestinal microflora.

Full Text

The Full Text of this article is available as a PDF (138K).

Articles from Epidemiology and Infection are provided here courtesy of Cambridge University Press


Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...


Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...