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J Bacteriol. 1970 Nov; 104(2): 910–921.
PMCID: PMC285075

Induction, Morphogenesis, and Germination of the Chlamydospore of Candida albicans


Early log phase yeast cells of Candida albicans transformed into suspensor cells and chlamydospores when streaked on washed agar without added nutrients. The transformation was apparently a result of endogenous metabolism since starved yeast cells did not form chlamydospores. Addition of glucose (5 mg/ml) to washed agar completely suppressed chlamydospore formation. Size of inoculum and age of inoculum markedly affected chlamydospore yield. Electron microscopy of thin sections revealed the chlamydospore wall to be double layered, the outer thin layer being continuous with the wall of the suspensor cell. A technique was devised to study germination of chlamydospores. Chlamydospores germinated by budding, and the fluorescent antibody technique was used to study the budding process.

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Selected References

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  • BARTNICKI-GARCIA S, NICKERSON WJ. Induction of yeast-like development in Mucor by carbon dioxide. J Bacteriol. 1962 Oct;84:829–840. [PMC free article] [PubMed]
  • Chung KL, Hawirko RZ, Isaac PK. Cell wall replication in Saccharomyces cerevisiae. Can J Microbiol. 1965 Dec;11(6):953–957. [PubMed]
  • Hayes AB. Chlamydospore production in Candida albicans. Mycopathol Mycol Appl. 1966 May 31;29(1):87–96. [PubMed]
  • LUFT JH. Improvements in epoxy resin embedding methods. J Biophys Biochem Cytol. 1961 Feb;9:409–414. [PMC free article] [PubMed]
  • NICKERSON WJ, MANKOWSKI Z. A polysaccharide medium of known composition favoring chlamydospore formation in Candida albicans. J Infect Dis. 1953 Jan-Feb;92(1):20–25. [PubMed]
  • RINDERKNECHT H. Ultra-rapid fluorescent labelling of proteins. Nature. 1962 Jan 13;193:167–168. [PubMed]
  • SENTHESHANMUGANATHAN S, NICKERSON WJ. Nutritional control of cellular form in Trigonopsis variabilis. J Gen Microbiol. 1962 Mar;27:437–449. [PubMed]
  • WRIGHT BE, ANDERSON ML. Protein and amino acid turnover during differentiation in the slime mold. I. Utilization of endogenous amino acids and proteins. Biochim Biophys Acta. 1960 Sep 9;43:62–66. [PubMed]

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