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Proc Natl Acad Sci U S A. Feb 1970; 65(2): 357–362.
PMCID: PMC282910

A Specific Complex between a Restriction Endonuclease and Its DNA Substrate*

Abstract

In the presence of Mg++, ATP, and S-adenosylmethionine, the DNA restriction endonuclease R·K forms a specific complex with its DNA substrate. The complex can be detected by its retention on nitrocellulose membranes.

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Selected References

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