• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of jbacterPermissionsJournals.ASM.orgJournalJB ArticleJournal InfoAuthorsReviewers
J Bacteriol. Nov 1962; 84(5): 902–910.
PMCID: PMC277988



Sugino, Yoshinobu (Osaka University, Osaka, Japan) and Yukinori Hirota. Conjugal fertility associated with resistance factor R in Escherichia coli. J. Bacteriol. 84:902–910. 1962.—The introduction of the contagious drug-resistance factor, R, into an F strain of Escherichia coli allows the R+F strain to mate with FR strains. The chromosome fragment transferred from the R+ cell is relatively large, comparable to the conjugation between F+ or Hfr male and F female bacteria. The complex R factor has been analyzed by transduction with phage Pl. Within the R factor, the fertility determinant is inseparable from the determinant responsible for its infectivity, but can be separated from the loci for drug resistance. R thus resembles the category of complex F factors (F-primes) previously analyzed.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.1M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • BHASKARAN K. Recombination of characters between mutant stocks of Vibrio cholerae, strain 162. J Gen Microbiol. 1960 Aug;23:47–54. [PubMed]
  • HARADA K, SUZUKI M, KAMEDA M, MITSUHASHI S. On the drug-resistance of enteric bacteria. 2) Transmission of the drug-resistance among Enterobacteriaceae. Jpn J Exp Med. 1960 Aug;30:289–299. [PubMed]
  • Hirota Y. THE EFFECT OF ACRIDINE DYES ON MATING TYPE FACTORS IN ESCHERICHIA COLI. Proc Natl Acad Sci U S A. 1960 Jan;46(1):57–64. [PMC free article] [PubMed]
  • HOLLOWAY BW, FARGIE B. Fertility factors and genetic linkage in Pseudomonas aeruginosa. J Bacteriol. 1960 Sep;80:362–368. [PMC free article] [PubMed]
  • Lederberg J. SIBLING RECOMBINANTS IN ZYGOTE PEDIGREES OF ESCHERICHIA COLI. Proc Natl Acad Sci U S A. 1957 Dec 15;43(12):1060–1065. [PMC free article] [PubMed]
  • Lederberg J, Cavalli LL, Lederberg EM. Sex Compatibility in Escherichia Coli. Genetics. 1952 Nov;37(6):720–730. [PMC free article] [PubMed]
  • LEDERBERG J, LEDERBERG EM, ZINDER ND, LIVELY ER. Recombination analysis of bacterial heredity. Cold Spring Harb Symp Quant Biol. 1951;16:413–443. [PubMed]
  • LEDERBERG J, LEDERBERG EM. Replica plating and indirect selection of bacterial mutants. J Bacteriol. 1952 Mar;63(3):399–406. [PMC free article] [PubMed]
  • LENNOX ES. Transduction of linked genetic characters of the host by bacteriophage P1. Virology. 1955 Jul;1(2):190–206. [PubMed]
  • LOEB T. Isolation of a bacteriophage specific for the F plus and Hfr mating types of Escherichia coli K-12. Science. 1960 Mar 25;131(3404):932–933. [PubMed]
  • MITSUHASHI S, HARADA K, KAMEDA M. Elimination of transmissible drug-resistance by treatment with acriflavin. Nature. 1961 Mar 18;189:947–947. [PubMed]
  • CLOWES RC. Colicine factors as fertility factors in bacteria: Escherichia coli K-12. Nature. 1961 Jun 10;190:988–989. [PubMed]
  • WATANABE T, FUKASAWA T. Episome-mediated transfer of drug resistance in Enterobacteriaceae. II. Elimination of resistance factors with acridine dyes. J Bacteriol. 1961 May;81:679–683. [PMC free article] [PubMed]
  • WATANABE T, FUKASAWA T. Episome-mediated transfer of drug resistance in Enterobacteriaceae. III. Transduotion of resistance factors. J Bacteriol. 1961 Aug;82:202–209. [PMC free article] [PubMed]
  • ZINDER ND. A bacteriophage specific for F- Salmonella strains. Science. 1961 Jun 30;133(3470):2069–2070. [PubMed]

Articles from Journal of Bacteriology are provided here courtesy of American Society for Microbiology (ASM)


Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...


Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...