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Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas
Frank Westermann, Daniel Muth, Axel Benner, Tobias Bauer, Kai-Oliver Henrich, André Oberthuer, Benedikt Brors, Tim Beissbarth, Jo Vandesompele, Filip Pattyn, Barbara Hero, Rainer König, Matthias Fischer, Manfred Schwab
Genome Biol. 2008; 9(10): R150. Published online 2008 October 13. doi: 10.1186/gb-2008-9-10-r150
PMCID:
PMC2760877
Abstract Full Text PDF–738K Supplementary Material

Is Cited by the Following 22 Articles in this Archive:

MiRNA-335 suppresses neuroblastoma cell invasiveness by direct targeting of multiple genes from the non-canonical TGF-β signalling pathway
Jennifer Lynch, Joanna Fay, Maria Meehan, Kenneth Bryan, Karen M. Watters, Derek M. Murphy, Raymond L. Stallings
Carcinogenesis. 2012 May; 33(5): 976–985. Published online 2012 March 1. doi: 10.1093/carcin/bgs114
PMCID:
PMC3334516
Free in PMC on 2013/05/01
Meta-analysis of 8q24 for seven cancers reveals a locus between NOV and ENPP2 associated with cancer development
Abra G Brisbin, Yan W Asmann, Honglin Song, Ya-Yu Tsai, Jeremiah A Aakre, Ping Yang, Robert B Jenkins, Paul Pharoah, Fredrick Schumacher, David V Conti, David J Duggan, Mark Jenkins, John Hopper, Steven Gallinger, Polly Newcomb, Graham Casey, Thomas A Sellers, Brooke L Fridley
BMC Med Genet. 2011; 12: 156. Published online 2011 December 5. doi: 10.1186/1471-2350-12-156
PMCID:
PMC3267702
Abstract Full Text PDF–650K Supplementary Material
miRNA Expression Profiling of the Murine TH-MYCN Neuroblastoma Model Reveals Similarities with Human Tumors and Identifies Novel Candidate MiRNAs
Marta Terrile, Kenneth Bryan, Lynsey Vaughan, Albert Hallsworth, Hannah Webber, Louis Chesler, Raymond L. Stallings
PLoS One. 2011; 6(12): e28356. Published online 2011 December 2. doi: 10.1371/journal.pone.0028356
PMCID:
PMC3229581
Abstract Full Text PDF–804K Supplementary Material
Identification of Cytotoxic Drugs That Selectively Target Tumor Cells with MYC Overexpression
Anna Frenzel, Hanna Zirath, Marina Vita, Ami Albihn, Marie Arsenian Henriksson
PLoS One. 2011; 6(11): e27988. Published online 2011 November 23. doi: 10.1371/journal.pone.0027988
PMCID:
PMC3223192
Abstract Full Text PDF–940K Supplementary Material
Enhancers regulate progression of development in mammalian cells
Anna-Lena Kranz, Roland Eils, Rainer König
Nucleic Acids Res. 2011 November; 39(20): 8689–8702. Published online 2011 July 23. doi: 10.1093/nar/gkr602
PMCID:
PMC3203619
Abstract Full Text PDF–4.2M Supplementary Material
Co-Localization of the Oncogenic Transcription Factor MYCN and the DNA Methyl Binding Protein MeCP2 at Genomic Sites in Neuroblastoma
Derek M. Murphy, Patrick G. Buckley, Sudipto Das, Karen M. Watters, Kenneth Bryan, Raymond L. Stallings
PLoS One. 2011; 6(6): e21436. Published online 2011 June 22. doi: 10.1371/journal.pone.0021436
PMCID:
PMC3120883
Abstract Full Text PDF–1.5M Supplementary Material
Tumour-suppressor microRNAs let-7 and mir-101 target the proto-oncogene MYCN and inhibit cell proliferation in MYCN-amplified neuroblastoma
J Buechner, E Tømte, B H Haug, J R Henriksen, C Løkke, T Flægstad, C Einvik
Br J Cancer. 2011 July 12; 105(2): 296–303. Published online 2011 June 7. doi: 10.1038/bjc.2011.220
PMCID:
PMC3142803
Free in PMC on 2012/07/12
Identification of Phosphoproteins as Possible Differentiation Markers in All-Trans-Retinoic Acid-Treated Neuroblastoma Cells
Giorgia Mandili, Cristina Marini, Franco Carta, Cristina Zanini, Mauro Prato, Amina Khadjavi, Franco Turrini, Giuliana Giribaldi
PLoS One. 2011; 6(5): e18254. Published online 2011 May 5. doi: 10.1371/journal.pone.0018254
PMCID:
PMC3088664
Abstract Full Text PDF–528K
Exon array analysis reveals neuroblastoma tumors have distinct alternative splicing patterns according to stage and MYCN amplification status
Xiang Guo, Qing-Rong Chen, Young K Song, Jun S Wei, Javed Khan
BMC Med Genomics. 2011; 4: 35. Published online 2011 April 18. doi: 10.1186/1755-8794-4-35
PMCID:
PMC3096898
Abstract Full Text PDF–851K Supplementary Material
A 6-gene signature identifies four molecular subgroups of neuroblastoma
Frida Abel, Daniel Dalevi, Maria Nethander, Rebecka Jörnsten, Katleen De Preter, Joëlle Vermeulen, Raymond Stallings, Per Kogner, John Maris, Staffan Nilsson
Cancer Cell Int. 2011; 11: 9. Published online 2011 April 14. doi: 10.1186/1475-2867-11-9
PMCID:
PMC3095533
Abstract Full Text PDF–3.9M Supplementary Material
MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival
E A Afanasyeva, P Mestdagh, C Kumps, J Vandesompele, V Ehemann, J Theissen, M Fischer, M Zapatka, B Brors, L Savelyeva, V Sagulenko, F Speleman, M Schwab, F Westermann
Cell Death Differ. 2011 June; 18(6): 974–984. Published online 2011 January 14. doi: 10.1038/cdd.2010.164
PMCID:
PMC3131937
Free in PMC on 2012/06/01
Conditional expression of retrovirally delivered anti-MYCN shRNA as an in vitro model system to study neuronal differentiation in MYCN-amplified neuroblastoma
Jørn R Henriksen, Bjørn Helge Haug, Jochen Buechner, Ellen Tømte, Cecilie Løkke, Trond Flaegstad, Christer Einvik
BMC Dev Biol. 2011; 11: 1. Published online 2011 January 3. doi: 10.1186/1471-213X-11-1
PMCID:
PMC3022612
Abstract Full Text PDF–1.5M Supplementary Material
Identification of the Rage-dependent gene regulatory network in a mouse model of skin inflammation
Astrid Riehl, Tobias Bauer, Benedikt Brors, Hauke Busch, Regina Mark, Julia Németh, Christoffer Gebhardt, Angelika Bierhaus, Peter Nawroth, Roland Eils, Rainer König, Peter Angel, Jochen Hess
BMC Genomics. 2010; 11: 537. Published online 2010 October 5. doi: 10.1186/1471-2164-11-537
PMCID:
PMC3091686
Abstract Full Text PDF–1.0M Supplementary Material
MicroRNA Mediates DNA De-methylation Events Triggered By Retinoic Acid During Neuroblastoma Cell Differentiation
Sudipto Das, Niamh Foley, Kenneth Bryan, Karen M Watters, Isabella Bray, Derek M Murphy, Patrick G Buckley, Raymond L Stallings
Cancer Res. Author manuscript; available in PMC 2011 October 15.
Published in final edited form as: Cancer Res. 2010 October 15; 70(20): 7874–7881. Published online 2010 September 14. doi: 10.1158/0008-5472.CAN-10-1534
PMCID:
PMC2955783
Abstract Full Text PDF–868K Supplementary Material
miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis
Li Ma, Jennifer Young, Harsha Prabhala, Elizabeth Pan, Pieter Mestdagh, Daniel Muth, Julie Teruya-Feldstein, Ferenc Reinhardt, Tamer T. Onder, Scott Valastyan, Frank Westermann, Frank Speleman, Jo Vandesompele, Robert A. Weinberg
Nat Cell Biol. Author manuscript; available in PMC 2010 September 1.
Published in final edited form as: Nat Cell Biol. 2010 March; 12(3): 247–256. Published online 2010 February 21. doi: 10.1038/ncb2024
PMCID:
PMC2845545
Abstract Full Text PDF–3.1M Supplementary Material
p53 is a Direct Transcriptional Target of MYCN in Neuroblastoma
Lindi Chen, Nunzio Iraci, Samuele Gherardi, Laura D. Gamble, Katrina M. Wood, Giovanni Perini, John Lunec, Deborah A. Tweddle
Cancer Res. Author manuscript; available in PMC 2010 August 15.
Published in final edited form as: Cancer Res. 2010 February 15; 70(4): 1377–1388. Published online 2010 February 9. doi: 10.1158/0008-5472.CAN-09-2598
PMCID:
PMC2875109
Abstract Full Text PDF–1.4M Supplementary Material
Myc proteins as therapeutic targets
WC Gustafson, WA Weiss
Oncogene. Author manuscript; available in PMC 2010 September 4.
Published in final edited form as: Oncogene. 2010 March 4; 29(9): 1249–1259. Published online 2010 January 25. doi: 10.1038/onc.2009.512
PMCID:
PMC2904682
Abstract Full Text PDF–522K
Global MYCN Transcription Factor Binding Analysis in Neuroblastoma Reveals Association with Distinct E-Box Motifs and Regions of DNA Hypermethylation
Derek M. Murphy, Patrick G. Buckley, Kenneth Bryan, Sudipto Das, Leah Alcock, Niamh H. Foley, Suzanne Prenter, Isabella Bray, Karen M. Watters, Desmond Higgins, Raymond L. Stallings
PLoS One. 2009; 4(12): e8154. Published online 2009 December 4. doi: 10.1371/journal.pone.0008154
PMCID:
PMC2781550
Abstract Full Text PDF–500K Supplementary Material
Molecular Pathways: Disrupting polyamine homeostasis as a therapeutic strategy for neuroblastoma
Nicholas F. Evageliou, Michael D. Hogarty
Clin Cancer Res. Author manuscript; available in PMC 2010 October 1.
Published in final edited form as: Clin Cancer Res. 2009 October 1; 15(19): 5956–5961. Published online 2009 September 29. doi: 10.1158/1078-0432.CCR-08-3213
PMCID:
PMC2923453
Abstract Full Text PDF–1.0M
Mdm2 Deficiency Suppresses MYCN-Driven Neuroblastoma Tumorigenesis In Vivo
Zaowen Chen, Yunfu Lin, Eveline Barbieri, Sue Burlingame, John Hicks, Andrew Ludwig, Jason M Shohet
Neoplasia. 2009 August; 11(8): 753–762.
PMCID:
PMC2713395
Abstract Full Text PDF–1.3M
The emerging molecular pathogenesis of neuroblastoma: implications for improved risk assessment and targeted therapy
Nadine Van Roy, Katleen De Preter, Jasmien Hoebeeck, Tom Van Maerken, Filip Pattyn, Pieter Mestdagh, Joëlle Vermeulen, Jo Vandesompele, Frank Speleman
Genome Med. 2009; 1(7): 74. Published online 2009 July 27. doi: 10.1186/gm74
PMCID:
PMC2717400
Abstract Full Text PDF–232K
A novel and universal method for microRNA RT-qPCR data normalization
Pieter Mestdagh, Pieter Van Vlierberghe, An De Weer, Daniel Muth, Frank Westermann, Frank Speleman, Jo Vandesompele
Genome Biol. 2009; 10(6): R64. Published online 2009 June 16. doi: 10.1186/gb-2009-10-6-r64
PMCID:
PMC2718498
Abstract Full Text PDF–292K Supplementary Material
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