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BRCA1-deficient mammary tumor cells are dependent on EZH2 expression and sensitive to Polycomb Repressive Complex 2-inhibitor 3-deazaneplanocin A
Julian Puppe, Rinske Drost, Xiaoling Liu, Simon A Joosse, Bastiaan Evers, Paulien Cornelissen-Steijger, Petra Nederlof, Qiang Yu, Jos Jonkers, Maarten van Lohuizen, Alexandra M Pietersen
Breast Cancer Res. 2009; 11(4): R63. Published online 2009 August 26. doi: 10.1186/bcr2354
PMCID:
PMC2750125
Abstract Full Text PDF–2.2M Supplementary Material

Is Cited by the Following 13 Articles in this Archive:

EZH2 Methyltransferase and H3K27 Methylation in Breast Cancer
Kyung Hyun Yoo, Lothar Hennighausen
Int J Biol Sci. 2012; 8(1): 59–65. Published online 2011 November 18.
PMCID:
PMC3226033
Abstract Full Text PDF–696K
EZH2 Methyltransferase and H3K27 Methylation in Breast Cancer
Kyung Hyun Yoo, Lothar Hennighausen
Int J Biol Sci. 2012; 8(1): 59–65. Published online 2011 November 18.
PMCID:
PMC3226033
Abstract Full Text PDF–696K
(-)-Epigallocatechin-3-gallate and DZNep reduce polycomb protein level via a proteasome-dependent mechanism in skin cancer cells
Subhasree Roy Choudhury, Sivaprakasam Balasubramanian, Yap Ching Chew, Bingshe Han, Victor E. Marquez, Richard L. Eckert
Carcinogenesis. 2011 October; 32(10): 1525–1532. Published online 2011 July 27. doi: 10.1093/carcin/bgr171
PMCID:
PMC3179425
Free in PMC on 2012/10/01
Increased Risk for Distant Metastasis in Patients with Familial Early-Stage Breast Cancer and High EZH2 Expression
Sharon Hensley Alford, Katherine Toy, Sofia D. Merajver, Celina G. Kleer
Breast Cancer Res Treat. Author manuscript; available in PMC 2012 April 1.
Published in final edited form as: Breast Cancer Res Treat. 2012 April; 132(2): 429–437. Published online 2011 May 26. doi: 10.1007/s10549-011-1591-2
PMCID:
PMC3311223
Abstract Full Text PDF–1.6M Supplementary Material
Inhibition of Histone Lysine Methylation Enhances Expression of Cancer-Testis Genes in Lung Cancer Cells: Implications for Adoptive Immunotherapy of Cancer
Mahadev Rao, Nachimuthu Chinnasamy, Julie A. Hong, Yuwei Zhang, Mary Zhang, Sichuan Xi, Fang Liu, Victor E. Marquez, Richard A. Morgan, David S. Schrump
Cancer Res. Author manuscript; available in PMC 2012 June 15.
Published in final edited form as: Cancer Res. 2011 June 15; 71(12): 4192–4204. Published online 2011 May 5. doi: 10.1158/0008-5472.CAN-10-2442
PMCID:
PMC3116976
Free in PMC on 2012/06/15
Pharmacologic disruption of Polycomb Repressive Complex 2 inhibits tumorigenicity and tumor progression in prostate cancer
Francesco Crea, Elaine M Hurt, Lesley A Mathews, Stephanie M Cabarcas, Lei Sun, Victor E Marquez, Romano Danesi, William L Farrar
Mol Cancer. 2011; 10: 40. Published online 2011 April 18. doi: 10.1186/1476-4598-10-40
PMCID:
PMC3100246
Abstract Full Text PDF–1.3M Supplementary Material
Histone Methyltransferase EZH2 Induces Akt-Dependent Genomic Instability and BRCA1 Inhibition in Breast Cancer
Maria E. Gonzalez, Matthew L. DuPrie, Heather Krueger, Sofia D. Merajver, Alejandra C. Ventura, Kathy A. Toy, Celina G. Kleer
Cancer Res. Author manuscript; available in PMC 2012 March 15.
Published in final edited form as: Cancer Res. 2011 March 15; 71(6): 2360–2370. doi: 10.1158/0008-5472.CAN-10-1933
PMCID:
PMC3071296
Abstract Full Text PDF–2.1M Supplementary Material
EZH2 and ALDH-1 mark breast epithelium at risk for breast cancer development
Lakshmi P Kunju, Cynthia Cookingham, Kathy A. Toy, Wei Chen, Michael S. Sabel, Celina G. Kleer
Mod Pathol. Author manuscript; available in PMC 2012 June 1.
Published in final edited form as: Mod Pathol. 2011 June; 24(6): 786–793. Published online 2011 March 11. doi: 10.1038/modpathol.2011.8
PMCID:
PMC3106137
Free in PMC on 2012/06/01
BRCA1, PARP, and 53BP1: conditional synthetic lethality and synthetic viability
Amal Aly, Shridar Ganesan
J Mol Cell Biol. 2011 February; 3(1): 66–74. doi: 10.1093/jmcb/mjq055
PMCID:
PMC3030974
Abstract Full Text PDF–316K
BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair
Ismail Hassan Ismail, Christi Andrin, Darin McDonald, Michael J. Hendzel
J Cell Biol. 2010 October 4; 191(1): 45–60. doi: 10.1083/jcb.201003034
PMCID:
PMC2953429
Abstract Full Text PDF–3.4M Supplementary Material
Long-term stability of demethylation after transient exposure to 5-aza-2′-deoxycytidine correlates with sustained RNA polymerase II occupancy
Jacob D. Kagey, Priya Kapoor-Vazirani, Michael T. McCabe, Doris R. Powell, Paula M. Vertino
Mol Cancer Res. Author manuscript; available in PMC 2011 July 1.
Published in final edited form as: Mol Cancer Res. 2010 July; 8(7): 1048–1059. Published online 2010 June 29. doi: 10.1158/1541-7786.MCR-10-0189
PMCID:
PMC3086892
Abstract Full Text PDF–1.2M Supplementary Material
Nucleoside Drugs Induce Cellular Differentiation by Caspase-Dependent Degradation of Stem Cell Factors
Tanja Musch, Yuva Öz, Frank Lyko, Achim Breiling
PLoS One. 2010; 5(5): e10726. Published online 2010 May 19. doi: 10.1371/journal.pone.0010726
PMCID:
PMC2873290
Abstract Full Text PDF–1.5M Supplementary Material
Development of 'synthetic lethal' strategies to target BRCA1-deficient breast cancer
Max S Wicha
Breast Cancer Res. 2009; 11(5): 108. Published online 2009 September 23. doi: 10.1186/bcr2362
PMCID:
PMC2790845
Abstract Full Text PDF–48K
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