• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of jcmPermissionsJournals.ASM.orgJournalJCM ArticleJournal InfoAuthorsReviewers
J Clin Microbiol. Feb 1981; 13(2): 335–343.
PMCID: PMC273787

Phospholipase D activity of Corynebacterium pseudotuberculosis (Corynebacterium ovis) and Corynebacterium ulcerans, a distinctive marker within the genus Corynebacterium.

Abstract

A search has been made for corynebacterial phospholipase D, "ovis toxin," a sphingomyelinase (phosphatidylcholine phosphohydrolase, EC 3.1.4.4), among a wide variety of corynebacteria. Phospholipase D activity has been found in strains exhibiting the biochemical properties characteristic of Corynebacterium pseudotuberculosis or of Corynebacterium ulcerans and in no other species of Corynebacterium. Methods for the assay of phospholipase D as a sphingomyelinase and methods for screening for phospholipase D in the presence of Corynebacterium equi on washed sheep blood agar are discussed.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.0M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Barksdale L. Corynebacterium diphtheriae and its relatives. Bacteriol Rev. 1970 Dec;34(4):378–422. [PMC free article] [PubMed]
  • BARKSDALE WL, LI K, CUMMINS CS, HARRIS H. The mutation of Corynebacterium pyogenes to Corynebacterium haemolyticum. J Gen Microbiol. 1957 Jun;16(3):749–758. [PubMed]
  • Bernheimer AW, Avigad LS, Kim KS. Staphylococcal sphingomyelinase (beta-hemolysin). Ann N Y Acad Sci. 1974 Jul 31;236(0):292–306. [PubMed]
  • Bernheimer AW, Linder R, Avigad LS. Stepwise degradation of membrane sphingomyelin by corynebacterial phospholipases. Infect Immun. 1980 Jul;29(1):123–131. [PMC free article] [PubMed]
  • BERNHEIMER AW, SCHWARTZ LL. Isolation and composition of staphylococcal alpha toxin. J Gen Microbiol. 1963 Mar;30:455–468. [PubMed]
  • Brown J, Farnsworth R, Wannamaker LW, Johnson DW. CAMP factor of group B streptococci: production, assay, and neutralization by sera from immunized rabbits and experimentally infected cows. Infect Immun. 1974 Feb;9(2):377–383. [PMC free article] [PubMed]
  • FRASER G. Haemolytic activity of Corynebacterium ovis. Nature. 1961 Jan 21;189:246–246. [PubMed]
  • FRASER G. THE EFFECT ON ANIMAL ERYTHROCYTES OF COMBINATIONS OF DIFFUSIBLE SUBSTANCES PRODUCED BY BACTERIA. J Pathol Bacteriol. 1964 Jul;88:43–53. [PubMed]
  • Furness G, Evangelista AT. A diagnostic key employing biological reactions for differentiating pathogenic Corynebacterium genitalium (NSU corynebacteria) from commensals of the urogenital tract. Invest Urol. 1978 Jul;16(1):1–4. [PubMed]
  • Goel MC, Singh IP. Purification and characterization of Corynebacterium ovis exotoxin. J Comp Pathol. 1972 Jul;82(3):345–353. [PubMed]
  • HARTWIGK H. ANTIHAEMOLYSINBILDUNG BEIM TIER VORKOMMENDER BETA-HAEMOLYTISCHER CORYNEBAKTERIEN. Zentralbl Bakteriol Orig. 1963 Dec;191:274–280. [PubMed]
  • HENRIKSEN SD, GRELLAND R. Toxigenicity, serological reactions and relationships of the diphtheria-like Corynebacteria. J Pathol Bacteriol. 1952 Jul;64(3):503–511. [PubMed]
  • HOWARD DH, JANN GJ. The isolation and characterization of bacteriophage active against the diphtheria-like corynebacteria. J Bacteriol. 1954 Sep;68(3):316–319. [PMC free article] [PubMed]
  • Kumazawa N, Yanagawa R. DNA base compositions of the three types of Coryneb-acterium renale. Jpn J Vet Res. 1969 Dec;17(4):115–120. [PubMed]
  • Lampidis T, Barksdale L. Park-Williams number 8 strain of Corynebacterium diphtheriae. J Bacteriol. 1971 Jan;105(1):77–85. [PMC free article] [PubMed]
  • Lanéelle MA, Asselineau J. Glycolipids of brevibacterium vitarumen. Biochim Biophys Acta. 1976 Jan 18;486(1):205–208. [PubMed]
  • Linder R, Bernheimer AW. Effect on sphingomyelin-containing liposomes of phospholipase D from Corynebacterium ovis and the cytolysin from Stoichactis helianthus. Biochim Biophys Acta. 1978 Aug 25;530(2):236–246. [PubMed]
  • Linder R, Bernheimer AW, Kim KS. Interaction between sphingomyelin and a cytolysin from the sea anemone Stoichactis helianthus. Biochim Biophys Acta. 1977 Jun 16;467(3):290–300. [PubMed]
  • Lovell R, Zaki MM. Studies on growth products of Corynebacterium ovis. I. The exotoxin and its lethal action on white mice. Res Vet Sci. 1966 Jul;7(3):302–306. [PubMed]
  • Lovell R, Zaki MM. Studies on growth products of Corynebacterium ovis. II. Other activities and their relationship. Res Vet Sci. 1966 Jul;7(3):307–311. [PubMed]
  • Maximescu P, Oprişan A, Pop A, Potorac E. Further studies on Corynebacterium species capable of producing diphtheria toxin (C. diphtheriae, C. ulcerans, C. ovis). J Gen Microbiol. 1974 May;82(1):49–56. [PubMed]
  • Maximesco P, Pop A, Oprişan A, Potorac E. Relations biologiques entre Corynebacterium ulcerans, Corynebacterium ovis et Corynebacterium diphtheriae. (Etude expérimentale) Arch Roum Pathol Exp Microbiol. 1968 Dec;27(4):733–750. [PubMed]
  • Meitert E, Saragea A, Petrovici A, Ionescu M. Studies on the host phage systems of Corynebacterium hofmanni species. Arch Roum Pathol Exp Microbiol. 1972 Mar;31(1):31–37. [PubMed]
  • Nelson JB. Response of mice to Corynebacterium kutscheri on footpad injection. Lab Anim Sci. 1973 Jun;23(3):370–372. [PubMed]
  • PARSONS EI. Induction of toxigenicity in non-toxigenic strains of C. diphtheriae with bacteriophages derived from non-toxigenic strains. Proc Soc Exp Biol Med. 1955 Oct;90(1):91–93. [PubMed]
  • Saragea A, Maximescu P, Meitert E, Stuparu I, Vieru E, Petruş V, Bălteanu C. Incidenţa şi distribuţia geografică a tipurilor fagice DE Corynebacterium diphtheriae în dinamica procesului epidemic al difteriei în republica socialistă România. Microbiol Parazitol Epidemiol (Bucur) 1966 Jul-Aug;11(4):351–362. [PubMed]
  • Soucek A, Michalec C, Soucková A. Identification and characterization of a new enzyme of the group "phospholipase D" isolated from Corynebacterium ovis. Biochim Biophys Acta. 1971 Jan 13;227(1):116–128. [PubMed]
  • Soucek A, Soucková A. Toxicity of bacterial sphingomyelinases D. J Hyg Epidemiol Microbiol Immunol. 1974;18(3):327–335. [PubMed]
  • Soucek A, Soucková A, Patocka F. Inhibition of the activity of alpha-toxin of Clostridium perfringens by toxic filtrates of corynebacteria. J Hyg Epidemiol Microbiol Immunol. 1967;11(1):123–124. [PubMed]
  • Soucková A, Soucek A. Inhibition of the hemolytic action of and lysins of Staphylococcus pyogenes by Corynebacterium hemolyticum, C. ovis and C. ulcerans. Toxicon. 1972 Aug;10(5):501–509. [PubMed]
  • Soucková A, Soucek A. Two distinct toxic proteins in Corynebacterium ulcerans. J Hyg Epidemiol Microbiol Immunol. 1974;18(3):336–341. [PubMed]
  • Toshach S, Valentine A, Sigurdson S. Bacteriophage typing of Corynebacterium diphtheriae. J Infect Dis. 1977 Nov;136(5):655–660. [PubMed]
  • Welby-Gieusse M, Lanéelle MA, Asselineau J. Structure des acides corynomycoliqes de Corynebacterium hofmanii et leur implication biogénétique. Eur J Biochem. 1970 Mar 1;13(1):164–167. [PubMed]
  • Yanagawa R. A numerical taxonomic study of the strains of three types of Corynebacterium renale. Can J Microbiol. 1975 Jun;21(6):824–827. [PubMed]
  • ZAKI MM. PRODUCTION OF A SOLUBLE SUBSTANCE BY CORYNEBACTERIUM OVIS. Nature. 1965 Feb 27;205:928–929. [PubMed]

Articles from Journal of Clinical Microbiology are provided here courtesy of American Society for Microbiology (ASM)

Formats:

Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...

Links

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...